WO2004081576A3 - Association de proteines polymorphes d'ancrage de kinase a des phenotypes cardiaques et procedes correspondants - Google Patents
Association de proteines polymorphes d'ancrage de kinase a des phenotypes cardiaques et procedes correspondants Download PDFInfo
- Publication number
- WO2004081576A3 WO2004081576A3 PCT/US2004/006740 US2004006740W WO2004081576A3 WO 2004081576 A3 WO2004081576 A3 WO 2004081576A3 US 2004006740 W US2004006740 W US 2004006740W WO 2004081576 A3 WO2004081576 A3 WO 2004081576A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- methods
- association
- polymorphic
- kinase anchor
- related methods
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 4
- 102000004169 proteins and genes Human genes 0.000 title abstract 2
- 108090000623 proteins and genes Proteins 0.000 title abstract 2
- 108091000080 Phosphotransferase Proteins 0.000 title 1
- 230000000747 cardiac effect Effects 0.000 title 1
- 102000020233 phosphotransferase Human genes 0.000 title 1
- 102000014022 A Kinase Anchor Proteins Human genes 0.000 abstract 4
- 108010011122 A Kinase Anchor Proteins Proteins 0.000 abstract 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 102000039446 nucleic acids Human genes 0.000 abstract 2
- 108020004707 nucleic acids Proteins 0.000 abstract 2
- 150000007523 nucleic acids Chemical class 0.000 abstract 2
- 208000024172 Cardiovascular disease Diseases 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 230000019491 signal transduction Effects 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6872—Intracellular protein regulatory factors and their receptors, e.g. including ion channels
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
La présente invention a trait à des protéines polymorphes d'ancrage de la kinase A et des acides nucléiques codant pour ces protéines. L'invention a également trait à des procédés de détection de protéines polymorphes d'ancrage de la kinase A et des acides nucléiques codant pour les protéines polymorphes d'ancrage de la kinase A, et des trousses destinés à être utilisées dans les procédés de détection. L'invention a trait en outre à des procédés d'identification de sujets atteints ou à risque de développer des maladies ou troubles, tels que ceux liés à la transduction de signal et/ou de maladie cardio-vasculaire. Enfin, l'invention a trait à des procédés de détermination de la susceptibilité à la morbidité et/ou la mortalité accrue ou prématurée.
Priority Applications (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP04718045A EP1601972A2 (fr) | 2003-03-07 | 2004-03-05 | Association de proteines polymorphes d'ancrage de kinase a des phenotypes cardiaques et procedes correspondants |
| AU2004219665A AU2004219665A1 (en) | 2003-03-07 | 2004-03-05 | Association of polymorphic kinase anchor proteins with cardiac phenotypes and related methods |
| US10/548,336 US20070141570A1 (en) | 2003-03-07 | 2004-03-05 | Association of polymorphic kinase anchor proteins with cardiac phenotypes and related methods |
| CA002518238A CA2518238A1 (fr) | 2003-03-07 | 2004-03-05 | Association de proteines polymorphes d'ancrage de kinase a des phenotypes cardiaques et procedes correspondants |
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US45335003P | 2003-03-07 | 2003-03-07 | |
| US45321503P | 2003-03-07 | 2003-03-07 | |
| US45320803P | 2003-03-07 | 2003-03-07 | |
| US60/453,350 | 2003-03-07 | ||
| US60/453,208 | 2003-03-07 | ||
| US60/453,215 | 2003-03-07 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| WO2004081576A2 WO2004081576A2 (fr) | 2004-09-23 |
| WO2004081576A3 true WO2004081576A3 (fr) | 2005-02-24 |
Family
ID=32995983
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/US2004/006740 WO2004081576A2 (fr) | 2003-03-07 | 2004-03-05 | Association de proteines polymorphes d'ancrage de kinase a des phenotypes cardiaques et procedes correspondants |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP1601972A2 (fr) |
| AU (1) | AU2004219665A1 (fr) |
| CA (1) | CA2518238A1 (fr) |
| WO (1) | WO2004081576A2 (fr) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8003317B2 (en) | 2003-07-31 | 2011-08-23 | Sequenom, Inc. | Methods for high level multiplexed polymerase chain reactions and homogeneous mass extension reactions |
| WO2011053134A2 (fr) * | 2009-10-26 | 2011-05-05 | Academisch Medisch Centrum Bij De Universiteit Van Amsterdam | Détermination du risque génétique de fibrillation ventriculaire |
| GB201208775D0 (en) | 2012-05-18 | 2012-07-04 | Uni I Oslo | Chemical compounds |
| GB201320506D0 (en) | 2013-11-26 | 2014-01-01 | Uni I Oslo | Cyclic amino compounds for the use in the treatment of cardiac disorders |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001027857A2 (fr) * | 1999-10-13 | 2001-04-19 | Sequenom, Inc. | Methodes de generation de bases de donnees et bases de donnees pour l'identification de marqueurs genetiques polymorphes |
| WO2002004489A2 (fr) * | 2000-07-10 | 2002-01-17 | Sequenom, Inc. | Proteines polymorphiques d'ancrage de kinase et acides nucleiques codant pour ces memes proteines |
-
2004
- 2004-03-05 AU AU2004219665A patent/AU2004219665A1/en not_active Abandoned
- 2004-03-05 WO PCT/US2004/006740 patent/WO2004081576A2/fr active Application Filing
- 2004-03-05 CA CA002518238A patent/CA2518238A1/fr not_active Abandoned
- 2004-03-05 EP EP04718045A patent/EP1601972A2/fr not_active Withdrawn
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001027857A2 (fr) * | 1999-10-13 | 2001-04-19 | Sequenom, Inc. | Methodes de generation de bases de donnees et bases de donnees pour l'identification de marqueurs genetiques polymorphes |
| WO2002004489A2 (fr) * | 2000-07-10 | 2002-01-17 | Sequenom, Inc. | Proteines polymorphiques d'ancrage de kinase et acides nucleiques codant pour ces memes proteines |
Non-Patent Citations (4)
| Title |
|---|
| CONG M. ET AL.: "Regulation of membrane targeting of the G protein-coupled receptor kinase 2 by protein kinase A and its anchoring protein AKAP79.", J. BIOL. CHEM., vol. 276, no. 18, 4 May 2001 (2001-05-04), pages 15192 - 15199, XP002305229 * |
| KAMMERER S. ET AL.: "Amino acid variant in the kinase binding domain of dual-specific A kinase-anchoring protein 2: a disease susceptibility polymorphism.", PROC. NATL. ACAD. SCI. USA, vol. 100, no. 7, 1 April 2003 (2003-04-01), pages 4066 - 4071, XP002294160 * |
| SHIH M. ET AL.: "Dynamic complexes of beta2-adrenergic receptors with protein kinases and phosphatases and the role of gravin.", J. BIOL. CHEM., vol. 274, no. 3, 15 January 1999 (1999-01-15), pages 1588 - 1595, XP002305230 * |
| SNAPIR A. ET AL.: "Effects of common polymorphisms in the alpha1A-, alpha2B-, beta1- and beta2-adrenoreceptors on haemodynamic responses to adrenaline.", CLIN. SCI., vol. 104, 9 January 2003 (2003-01-09), pages 509 - 520, XP002294159 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CA2518238A1 (fr) | 2004-09-23 |
| AU2004219665A1 (en) | 2004-09-23 |
| EP1601972A2 (fr) | 2005-12-07 |
| WO2004081576A2 (fr) | 2004-09-23 |
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