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WO2004073845A3 - Lyophilisation avec agitation - Google Patents

Lyophilisation avec agitation Download PDF

Info

Publication number
WO2004073845A3
WO2004073845A3 PCT/IB2004/001994 IB2004001994W WO2004073845A3 WO 2004073845 A3 WO2004073845 A3 WO 2004073845A3 IB 2004001994 W IB2004001994 W IB 2004001994W WO 2004073845 A3 WO2004073845 A3 WO 2004073845A3
Authority
WO
WIPO (PCT)
Prior art keywords
freeze drying
vessel
new
substances
stirred freeze
Prior art date
Application number
PCT/IB2004/001994
Other languages
English (en)
Other versions
WO2004073845A2 (fr
Inventor
Der Wel Peter Gerardus Van
Original Assignee
Hosokawa Micron Bv
Der Wel Peter Gerardus Van
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hosokawa Micron Bv, Der Wel Peter Gerardus Van filed Critical Hosokawa Micron Bv
Priority to AT04710955T priority Critical patent/ATE541171T1/de
Priority to EP04710955A priority patent/EP1601919B1/fr
Publication of WO2004073845A2 publication Critical patent/WO2004073845A2/fr
Publication of WO2004073845A3 publication Critical patent/WO2004073845A3/fr

Links

Classifications

    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26—DRYING
    • F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B5/00—Drying solid materials or objects by processes not involving the application of heat
    • F26B5/04—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum
    • F26B5/06—Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F26—DRYING
    • F26B—DRYING SOLID MATERIALS OR OBJECTS BY REMOVING LIQUID THEREFROM
    • F26B11/00—Machines or apparatus for drying solid materials or objects with movement which is non-progressive
    • F26B11/12—Machines or apparatus for drying solid materials or objects with movement which is non-progressive in stationary drums or other mainly-closed receptacles with moving stirring devices
    • F26B11/14—Machines or apparatus for drying solid materials or objects with movement which is non-progressive in stationary drums or other mainly-closed receptacles with moving stirring devices the stirring device moving in a horizontal or slightly-inclined plane

Landscapes

  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Drying Of Solid Materials (AREA)

Abstract

L'invention concerne un procédé et un dispositif pour lyophiliser des solutions et des liquides contenant des substances solides. Selon l'invention, on utilise une cuve (1) en forme de cône renversé dans laquelle un organe mélangeur rotatif (3) est mis en mouvement, un interstice réduit étant ménagé entre cet organe et la paroi (2) de la cuve. Le procédé selon l'invention permet d'obtenir de façon avantageuse des produits à écoulement fluide. Il permet également d'obtenir de nouveaux mélanges homogènes de taille moléculaire comprenant au moins deux substances, ces mélanges pouvant être utilisés de façon remarquable dans l'industrie des nouveaux matériaux.
PCT/IB2004/001994 2003-02-13 2004-02-13 Lyophilisation avec agitation WO2004073845A2 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AT04710955T ATE541171T1 (de) 2003-02-13 2004-02-13 Gerührte gefriertrocknung
EP04710955A EP1601919B1 (fr) 2003-02-13 2004-02-13 Lyophilisation avec agitation

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NL1022668 2003-02-13
NL1022668A NL1022668C2 (nl) 2003-02-13 2003-02-13 Geroerd vriesdrogen.

Publications (2)

Publication Number Publication Date
WO2004073845A2 WO2004073845A2 (fr) 2004-09-02
WO2004073845A3 true WO2004073845A3 (fr) 2005-03-24

Family

ID=32906714

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2004/001994 WO2004073845A2 (fr) 2003-02-13 2004-02-13 Lyophilisation avec agitation

Country Status (4)

Country Link
EP (1) EP1601919B1 (fr)
AT (1) ATE541171T1 (fr)
NL (1) NL1022668C2 (fr)
WO (1) WO2004073845A2 (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007129340A1 (fr) * 2006-05-10 2007-11-15 Comber S.R.L. Séchoir à base conique
US9945611B2 (en) 2010-08-04 2018-04-17 Ima Life North America Inc. Bulk freeze drying using spray freezing and agitated drying
BR112013002675B1 (pt) 2010-08-04 2020-11-24 Ima Life North America Inc. sistemas e método de liofilização para liofilizar produto a granel
WO2012087232A1 (fr) * 2010-12-23 2012-06-28 Biotage Ab Appareil et procédé pour lyophilisation en film mince
CN106705574A (zh) * 2015-11-17 2017-05-24 上海东富龙科技股份有限公司 一种固体制剂制造设备和方法
CN108955165A (zh) * 2018-07-03 2018-12-07 南京拉艾夫医药科技有限公司 一种左卡尼汀原料药生产工艺的立式烘干机
JP2020085347A (ja) * 2018-11-26 2020-06-04 株式会社アーステクニカ フリーズドライ製品の製造方法及びフリーズドライシステム
NL2026893B1 (en) 2020-11-13 2022-06-30 Hosokawa Micron B V Freeze dryer and method for freeze drying
CN115451687A (zh) * 2022-11-08 2022-12-09 常州力马干燥科技有限公司 快速干燥电池原料装置

Citations (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1382926A (fr) * 1963-04-13 1964-12-24 Leybold Hochvakuum Anlagen Procédé de séchage sous congélation
US3352024A (en) * 1965-01-21 1967-11-14 Commw Scient Ind Res Org Freeze-drying process
GB1190314A (en) * 1967-07-27 1970-05-06 Nautamix Patent Ag A Method of Stirring material and a Device Therefor
GB1206066A (en) * 1968-05-11 1970-09-23 Leybold Heraeus Verwaltung Apparatus for continuously freeze-drying granular materials
US4245399A (en) * 1978-04-26 1981-01-20 Schering Aktiengesellschaft Material dryer with air and screw agitator
EP0042588A2 (fr) * 1980-06-19 1981-12-30 Bolz, Alfred, sen. Mélangeur conique à vis
US4501318A (en) * 1982-09-29 1985-02-26 Hebrank William H Heat recovery and air preheating apparatus
US4515483A (en) * 1982-08-16 1985-05-07 Schering Aktiengesellschaft Apparatus for removing substances from the inner walls of vessels
US4608764A (en) * 1984-05-19 1986-09-02 Glatt Maschinen-Und Apparatebau Ag Process of drying a particulate material and apparatus for implementing the process
US5230162A (en) * 1992-06-26 1993-07-27 Oyler Jr James R Systems and methods for the deliquification of liquid-containing substances by flash sublimation
US5336616A (en) * 1990-09-12 1994-08-09 Lifecell Corporation Method for processing and preserving collagen-based tissues for transplantation
EP0822000A1 (fr) * 1996-08-02 1998-02-04 Carlo Desinano Appareil d'agitation pour collecter des pigments principales utilisés pour la fabrication de peintures

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5948144A (en) 1997-10-07 1999-09-07 Genetics Institute, Inc. Lyophilizer system
JP2001263942A (ja) 2000-03-16 2001-09-26 Okawara Mfg Co Ltd 円錐型混合乾燥機

Patent Citations (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1382926A (fr) * 1963-04-13 1964-12-24 Leybold Hochvakuum Anlagen Procédé de séchage sous congélation
US3352024A (en) * 1965-01-21 1967-11-14 Commw Scient Ind Res Org Freeze-drying process
GB1190314A (en) * 1967-07-27 1970-05-06 Nautamix Patent Ag A Method of Stirring material and a Device Therefor
GB1206066A (en) * 1968-05-11 1970-09-23 Leybold Heraeus Verwaltung Apparatus for continuously freeze-drying granular materials
US4245399A (en) * 1978-04-26 1981-01-20 Schering Aktiengesellschaft Material dryer with air and screw agitator
EP0042588A2 (fr) * 1980-06-19 1981-12-30 Bolz, Alfred, sen. Mélangeur conique à vis
US4515483A (en) * 1982-08-16 1985-05-07 Schering Aktiengesellschaft Apparatus for removing substances from the inner walls of vessels
US4501318A (en) * 1982-09-29 1985-02-26 Hebrank William H Heat recovery and air preheating apparatus
US4608764A (en) * 1984-05-19 1986-09-02 Glatt Maschinen-Und Apparatebau Ag Process of drying a particulate material and apparatus for implementing the process
US5336616A (en) * 1990-09-12 1994-08-09 Lifecell Corporation Method for processing and preserving collagen-based tissues for transplantation
US5230162A (en) * 1992-06-26 1993-07-27 Oyler Jr James R Systems and methods for the deliquification of liquid-containing substances by flash sublimation
EP0822000A1 (fr) * 1996-08-02 1998-02-04 Carlo Desinano Appareil d'agitation pour collecter des pigments principales utilisés pour la fabrication de peintures

Also Published As

Publication number Publication date
EP1601919A2 (fr) 2005-12-07
WO2004073845A2 (fr) 2004-09-02
ATE541171T1 (de) 2012-01-15
EP1601919B1 (fr) 2012-01-11
NL1022668C2 (nl) 2004-08-16

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