WO2004060358A3 - Procede d'encapsulation d'un principe actif liposoluble par preparation d'une emulsion pit et emulsion obtenue - Google Patents
Procede d'encapsulation d'un principe actif liposoluble par preparation d'une emulsion pit et emulsion obtenue Download PDFInfo
- Publication number
- WO2004060358A3 WO2004060358A3 PCT/FR2003/003900 FR0303900W WO2004060358A3 WO 2004060358 A3 WO2004060358 A3 WO 2004060358A3 FR 0303900 W FR0303900 W FR 0303900W WO 2004060358 A3 WO2004060358 A3 WO 2004060358A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- emulsion
- temperature
- soluble substance
- encapsulating
- preparing
- Prior art date
Links
- 239000000839 emulsion Substances 0.000 title abstract 7
- 238000000034 method Methods 0.000 title abstract 4
- 239000000126 substance Substances 0.000 title abstract 3
- 239000012071 phase Substances 0.000 abstract 7
- 239000008346 aqueous phase Substances 0.000 abstract 2
- 239000002088 nanocapsule Substances 0.000 abstract 2
- 238000010791 quenching Methods 0.000 abstract 1
- 230000000171 quenching effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/16—Emollients or protectives, e.g. against radiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Dispersion Chemistry (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Dermatology (AREA)
- Toxicology (AREA)
- Nutrition Science (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Cosmetics (AREA)
- Medicinal Preparation (AREA)
- Colloid Chemistry (AREA)
- Manufacturing Of Micro-Capsules (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Procédé d'encapsulation d'un principe actif liposoluble dans des nanocapsules par préparation d'une émulsion caractérisé en ce que : a) on dispose d'une phase aqueuse et d'une phase grasse, b) on élève la température des deux phases jusqu'à une température supérieure à la température d'inversion de phase, c) on effectue le mélange des deux phases, d) on incorpore le principe actif liposoluble dans la phase liposoluble, e) on laisse la température s'abaisser jusqu'à la température d'inversion de phase, f) dès que l'inversion de phase est effective et que l'émulsion est en phase continue aqueuse on trempe l'émulsion obtenue pour abaisser sa température et émulsion susceptible d'être obtenue par le procédé caractérisée en ce que la taille des nanocapsules est inférieure en moyenne à 300 nm.
Priority Applications (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2003303610A AU2003303610B2 (en) | 2002-12-26 | 2003-12-24 | Method of encapsulating an active lipid-soluble substance by preparing a PIT emulsion and emulsion obtained |
| EP03814493A EP1578404A2 (fr) | 2002-12-26 | 2003-12-24 | Procede d encapsulation d'un principe actif liposoluble par preparation d' une emulsion pit et emulsion obtenue |
| JP2004564309A JP2006517141A (ja) | 2002-12-26 | 2003-12-24 | Ｐｉｔエマルジョンを作成することにより脂溶性活性成分のカプセルを形成する方法及びそのエマルジョン |
| CA002513273A CA2513273A1 (fr) | 2002-12-26 | 2003-12-24 | Procede d'encapsulation d'un principe actif liposoluble par preparation d'une emulsion pit et emulsion obtenue |
| US10/537,811 US20060134222A1 (en) | 2002-12-26 | 2003-12-24 | Process for encapsulating an active lipid-soluble substance by preparing a pit emulsion and emulsion obtained |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0216723A FR2849379B1 (fr) | 2002-12-26 | 2002-12-26 | Encapsulation d'actifs liposolubles |
| FR02/16723 | 2002-12-26 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| WO2004060358A2 WO2004060358A2 (fr) | 2004-07-22 |
| WO2004060358A3 true WO2004060358A3 (fr) | 2005-07-21 |
Family
ID=32480214
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/FR2003/003900 WO2004060358A2 (fr) | 2002-12-26 | 2003-12-24 | Procede d'encapsulation d'un principe actif liposoluble par preparation d'une emulsion pit et emulsion obtenue |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20060134222A1 (fr) |
| EP (1) | EP1578404A2 (fr) |
| JP (1) | JP2006517141A (fr) |
| CN (1) | CN100402019C (fr) |
| AU (1) | AU2003303610B2 (fr) |
| CA (1) | CA2513273A1 (fr) |
| FR (1) | FR2849379B1 (fr) |
| WO (1) | WO2004060358A2 (fr) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2003239845A1 (en) * | 2003-05-07 | 2004-11-26 | Ifac Gmbh And Co.Kg | Compositions for the targetted release of fragrances and aromas |
| KR20110096132A (ko) * | 2008-11-26 | 2011-08-29 | 리포프로틴 테크놀로지스, 인코포레이티드 | 레스베라트롤의 향상된 생활성 제제 |
| BE1020154A5 (nl) | 2012-03-22 | 2013-05-07 | Omega Pharma Innovation & Dev Nv | Samenstelling voor de behandeling van pediculose en overeenkomstig productiewerkwijze. |
| KR101645440B1 (ko) * | 2014-07-23 | 2016-08-05 | 코스맥스 주식회사 | 다량의 유분을 포함하면서 피부개선효과가 우수한 하이드로겔 마스크의 제조방법 및 이를 통하여 제조된 하이드로겔 조성물 |
| CN109330914B (zh) * | 2018-11-28 | 2022-02-01 | 广州艾卓生物科技有限公司 | 一种纳米神经酰胺乳液及其制备工艺和应用 |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5756110A (en) * | 1994-02-09 | 1998-05-26 | Societe L'oreal S.A. | Method for preparing storage-stable, ultrafine oil-in-water emulsion nanopigmented sunscreen/cosmetic compositions |
| WO2000071676A1 (fr) * | 1999-05-25 | 2000-11-30 | Cognis Deutschland Gmbh | Utilisation d'emulsions pit dans des procedes de fermentation |
| EP1093795A1 (fr) * | 1999-10-18 | 2001-04-25 | Beiersdorf AG | Filtres solaires cosmétiques ou dermatologiques sous forme de macro-émulsions ou micro-émulsions de type H/E contenant un ou plusieurs agents filmogènes sélectés parmi les copolymères de polyvinylpyrrolidone |
| WO2001064328A1 (fr) * | 2000-03-02 | 2001-09-07 | Mainelab | Nanocapsules lipidiques, procede de preparation et utilisation comme medicament |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5079322A (en) * | 1990-05-30 | 1992-01-07 | The Dow Chemical Company | Multifunctional cyclobutarene peroxide polymerization initiators |
-
2002
- 2002-12-26 FR FR0216723A patent/FR2849379B1/fr not_active Expired - Fee Related
-
2003
- 2003-12-24 US US10/537,811 patent/US20060134222A1/en not_active Abandoned
- 2003-12-24 CA CA002513273A patent/CA2513273A1/fr not_active Abandoned
- 2003-12-24 EP EP03814493A patent/EP1578404A2/fr not_active Withdrawn
- 2003-12-24 CN CNB2003801077299A patent/CN100402019C/zh not_active Expired - Fee Related
- 2003-12-24 JP JP2004564309A patent/JP2006517141A/ja active Pending
- 2003-12-24 WO PCT/FR2003/003900 patent/WO2004060358A2/fr active Application Filing
- 2003-12-24 AU AU2003303610A patent/AU2003303610B2/en not_active Expired - Fee Related
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5756110A (en) * | 1994-02-09 | 1998-05-26 | Societe L'oreal S.A. | Method for preparing storage-stable, ultrafine oil-in-water emulsion nanopigmented sunscreen/cosmetic compositions |
| WO2000071676A1 (fr) * | 1999-05-25 | 2000-11-30 | Cognis Deutschland Gmbh | Utilisation d'emulsions pit dans des procedes de fermentation |
| EP1093795A1 (fr) * | 1999-10-18 | 2001-04-25 | Beiersdorf AG | Filtres solaires cosmétiques ou dermatologiques sous forme de macro-émulsions ou micro-émulsions de type H/E contenant un ou plusieurs agents filmogènes sélectés parmi les copolymères de polyvinylpyrrolidone |
| WO2001064328A1 (fr) * | 2000-03-02 | 2001-09-07 | Mainelab | Nanocapsules lipidiques, procede de preparation et utilisation comme medicament |
Also Published As
| Publication number | Publication date |
|---|---|
| EP1578404A2 (fr) | 2005-09-28 |
| CN1731986A (zh) | 2006-02-08 |
| FR2849379A1 (fr) | 2004-07-02 |
| AU2003303610A1 (en) | 2004-07-29 |
| US20060134222A1 (en) | 2006-06-22 |
| CN100402019C (zh) | 2008-07-16 |
| JP2006517141A (ja) | 2006-07-20 |
| FR2849379B1 (fr) | 2005-02-11 |
| CA2513273A1 (fr) | 2004-07-22 |
| WO2004060358A2 (fr) | 2004-07-22 |
| AU2003303610B2 (en) | 2009-01-08 |
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