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WO2004055509A3 - Optical detection alignment coupling apparatus - Google Patents

Optical detection alignment coupling apparatus Download PDF

Info

Publication number
WO2004055509A3
WO2004055509A3 PCT/US2003/039971 US0339971W WO2004055509A3 WO 2004055509 A3 WO2004055509 A3 WO 2004055509A3 US 0339971 W US0339971 W US 0339971W WO 2004055509 A3 WO2004055509 A3 WO 2004055509A3
Authority
WO
WIPO (PCT)
Prior art keywords
optical detection
coupling apparatus
alignment coupling
detection alignment
capillary column
Prior art date
Application number
PCT/US2003/039971
Other languages
French (fr)
Other versions
WO2004055509A2 (en
Inventor
Varouj Amirkhanian
Paul Mooney
Original Assignee
Biocal Technology Inc
Varouj Amirkhanian
Paul Mooney
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/319,803 external-priority patent/US7250099B2/en
Application filed by Biocal Technology Inc, Varouj Amirkhanian, Paul Mooney filed Critical Biocal Technology Inc
Priority to AU2003302998A priority Critical patent/AU2003302998A1/en
Priority to US10/823,382 priority patent/US7622083B2/en
Publication of WO2004055509A2 publication Critical patent/WO2004055509A2/en
Publication of WO2004055509A3 publication Critical patent/WO2004055509A3/en
Priority to US10/973,828 priority patent/US7846315B2/en
Priority to US11/022,313 priority patent/US8114349B2/en
Priority to US11/152,030 priority patent/US7691247B2/en
Priority to US12/624,363 priority patent/US8092762B2/en
Priority to US12/754,533 priority patent/US8597485B2/en
Priority to US12/961,362 priority patent/US8460531B2/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44704—Details; Accessories
    • G01N27/44717—Arrangements for investigating the separated zones, e.g. localising zones
    • G01N27/44721—Arrangements for investigating the separated zones, e.g. localising zones by optical means
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N2021/6463—Optics
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N2021/6484—Optical fibres
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/08—Optical fibres; light guides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)

Abstract

An apparatus for aligning a capillary column with one or more excitation fibers and with one or more optical lens elements for Capillary Electrophoresis. The apparatus includes two identical blocks having a plurality of grooves for positioning and aligning the capillary column with the one or more excitation fibers, and a plurality of lens seats for optically coupling the lens elements with the capillary column. Each block includes a male and female part of mating the two identical blocks together.
PCT/US2003/039971 2002-01-28 2003-12-15 Optical detection alignment coupling apparatus WO2004055509A2 (en)

Priority Applications (8)

Application Number Priority Date Filing Date Title
AU2003302998A AU2003302998A1 (en) 2002-12-13 2003-12-15 Optical detection alignment coupling apparatus
US10/823,382 US7622083B2 (en) 2002-01-28 2004-04-12 Multi-capillary electrophoresis cartridge interface mechanism
US10/973,828 US7846315B2 (en) 2002-01-28 2004-10-25 Integrated bio-analysis and sample preparation system
US11/022,313 US8114349B2 (en) 2002-01-28 2004-12-23 Bio-analysis cartridge tracking and protection mechanism
US11/152,030 US7691247B2 (en) 2002-12-13 2005-06-13 Optical detection alignment coupling apparatus
US12/624,363 US8092762B2 (en) 2002-01-28 2009-11-23 Multi-capillary electrophoresis cartridge interface mechanism
US12/754,533 US8597485B2 (en) 2002-12-13 2010-04-05 Optical detection alignment coupling apparatus
US12/961,362 US8460531B2 (en) 2002-01-28 2010-12-06 Integrated bio-analysis and sample preparation system

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US10/319,803 2002-12-13
US10/319,803 US7250099B2 (en) 2002-12-13 2002-12-13 Optical detection alignment coupling apparatus
US46248103P 2003-04-11 2003-04-11
US60/462,481 2003-04-11

Related Parent Applications (2)

Application Number Title Priority Date Filing Date
US10/319,803 Continuation-In-Part US7250099B2 (en) 2002-01-28 2002-12-13 Optical detection alignment coupling apparatus
US10/823,382 Continuation-In-Part US7622083B2 (en) 2002-01-28 2004-04-12 Multi-capillary electrophoresis cartridge interface mechanism

Related Child Applications (5)

Application Number Title Priority Date Filing Date
US10/319,803 Continuation-In-Part US7250099B2 (en) 2002-01-28 2002-12-13 Optical detection alignment coupling apparatus
US10/823,382 Continuation-In-Part US7622083B2 (en) 2002-01-28 2004-04-12 Multi-capillary electrophoresis cartridge interface mechanism
US10/973,828 Continuation-In-Part US7846315B2 (en) 2002-01-28 2004-10-25 Integrated bio-analysis and sample preparation system
US11/022,313 Continuation-In-Part US8114349B2 (en) 2002-01-28 2004-12-23 Bio-analysis cartridge tracking and protection mechanism
US11/152,030 Continuation US7691247B2 (en) 2002-12-13 2005-06-13 Optical detection alignment coupling apparatus

Publications (2)

Publication Number Publication Date
WO2004055509A2 WO2004055509A2 (en) 2004-07-01
WO2004055509A3 true WO2004055509A3 (en) 2004-08-05

Family

ID=32599672

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2003/039971 WO2004055509A2 (en) 2002-01-28 2003-12-15 Optical detection alignment coupling apparatus

Country Status (2)

Country Link
AU (1) AU2003302998A1 (en)
WO (1) WO2004055509A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7093831B2 (en) 2017-07-19 2022-06-30 ペルキネルマー ヘルス サイエンシーズ， インコーポレイテッド Systems and methods for high-speed wide-field illumination scanning for in vivo fluorescence tomography of small animals

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1526372A3 (en) * 2004-11-02 2005-05-04 Agilent Technologies, Inc. Microfluidic system with adjustment for an optical detection
WO2006127590A2 (en) * 2005-05-20 2006-11-30 The Government Of The United States As Represented By The Secretary Of The Department Of Health And Human Services Microfluidic detection cell for stimulated radiation measurements
WO2010091400A2 (en) 2009-02-09 2010-08-12 Frederic Zenhausern Improvements in and relating to analysis
EP2672264A1 (en) 2012-06-06 2013-12-11 Qiagen Instruments AG Cartridge for a bio separation instrument, a method for calibrating a bio separation instrument, and a bio separation instrument

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5903348A (en) * 1997-03-12 1999-05-11 Nz Applied Technologies, Inc. System and method for molecular sample measurements
WO2002059589A2 (en) * 2001-01-26 2002-08-01 Biocal Technology, Inc. Multi-channel bio-separation cartridge
CA2348359A1 (en) * 2001-05-24 2002-11-24 David R. Rolston Ferrule for an array of optical fibers and connector structure including this ferrule

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5903348A (en) * 1997-03-12 1999-05-11 Nz Applied Technologies, Inc. System and method for molecular sample measurements
WO2002059589A2 (en) * 2001-01-26 2002-08-01 Biocal Technology, Inc. Multi-channel bio-separation cartridge
CA2348359A1 (en) * 2001-05-24 2002-11-24 David R. Rolston Ferrule for an array of optical fibers and connector structure including this ferrule

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7093831B2 (en) 2017-07-19 2022-06-30 ペルキネルマー ヘルス サイエンシーズ， インコーポレイテッド Systems and methods for high-speed wide-field illumination scanning for in vivo fluorescence tomography of small animals

Also Published As

Publication number Publication date
WO2004055509A2 (en) 2004-07-01
AU2003302998A1 (en) 2004-07-09
AU2003302998A8 (en) 2004-07-09

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