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WO2004047799A3 - Pellets containing non-aqueous fluids and the process for their preparation - Google Patents

Pellets containing non-aqueous fluids and the process for their preparation Download PDF

Info

Publication number
WO2004047799A3
WO2004047799A3 PCT/SI2003/000042 SI0300042W WO2004047799A3 WO 2004047799 A3 WO2004047799 A3 WO 2004047799A3 SI 0300042 W SI0300042 W SI 0300042W WO 2004047799 A3 WO2004047799 A3 WO 2004047799A3
Authority
WO
WIPO (PCT)
Prior art keywords
preparation
containing non
aqueous fluids
pellets containing
polyhydroxy alcohol
Prior art date
Application number
PCT/SI2003/000042
Other languages
French (fr)
Other versions
WO2004047799A2 (en
Inventor
Judita Sirca
Stanko Srcic
Rok Dreu
Original Assignee
Lek Pharmaceuticals
Judita Sirca
Stanko Srcic
Rok Dreu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lek Pharmaceuticals, Judita Sirca, Stanko Srcic, Rok Dreu filed Critical Lek Pharmaceuticals
Priority to AU2003302380A priority Critical patent/AU2003302380A1/en
Publication of WO2004047799A2 publication Critical patent/WO2004047799A2/en
Publication of WO2004047799A3 publication Critical patent/WO2004047799A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0026—Blood substitute; Oxygen transporting formulations; Plasma extender
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Pellets characterized in that an agglomerating fluid used for their preparation is liquid polyhydroxy alcohol which may be in a mixture with water or another pharmaceutically acceptable solvent which is more easily volatile than said polyhydroxy alcohol and further characterized in that said agglomerating fluid completely or partly remains in a finished pharmaceutical dosage form.
PCT/SI2003/000042 2002-11-27 2003-11-25 Pellets containing non-aqueous fluids and the process for their preparation WO2004047799A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2003302380A AU2003302380A1 (en) 2002-11-27 2003-11-25 Pellets containing non-aqueous fluids and the process for their preparation

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SIP200200286 2002-11-27
SI200200286A SI21353A (en) 2002-11-27 2002-11-27 Pellet-containing anhydrous liquids and process of their preparation

Publications (2)

Publication Number Publication Date
WO2004047799A2 WO2004047799A2 (en) 2004-06-10
WO2004047799A3 true WO2004047799A3 (en) 2004-09-10

Family

ID=32391127

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/SI2003/000042 WO2004047799A2 (en) 2002-11-27 2003-11-25 Pellets containing non-aqueous fluids and the process for their preparation

Country Status (3)

Country Link
AU (1) AU2003302380A1 (en)
SI (1) SI21353A (en)
WO (1) WO2004047799A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009067684A1 (en) * 2007-11-21 2009-05-28 Capricorn Pharma Inc. Modified release niacin formulations

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6290990B1 (en) * 1994-04-18 2001-09-18 Basf Aktiengesellschaft Slow-release matrix pellets and the production thereof
US20020123503A1 (en) * 2000-12-21 2002-09-05 Malcolm Ross Cabergoline pharmaceutical compositions and methods of use thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6290990B1 (en) * 1994-04-18 2001-09-18 Basf Aktiengesellschaft Slow-release matrix pellets and the production thereof
US20020123503A1 (en) * 2000-12-21 2002-09-05 Malcolm Ross Cabergoline pharmaceutical compositions and methods of use thereof

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; 15 May 2002 (2002-05-15), BOUTELL S ET AL: "The influence of liquid binder on the liquid mobility and preparation of spherical granules by the process of extrusion/spheronization", XP002283561, Database accession no. PREV200200362166 *
INTERNATIONAL JOURNAL OF PHARMACEUTICS (KIDLINGTON), vol. 238, no. 1-2, 15 May 2002 (2002-05-15), pages 61 - 76, ISSN: 0378-5173 *
LWA M F L ET AL: "EFFECT OF COMMON CLASSES OF EXCIPIENTS ON EXTRUSION-SPHERONIZATION", JOURNAL OF MICROENCAPSULATION, TAYLOR AND FRANCIS INC. LONDON, GB, vol. 14, no. 5, 1 September 1997 (1997-09-01), pages 647 - 657, XP000659520, ISSN: 0265-2048 *

Also Published As

Publication number Publication date
WO2004047799A2 (en) 2004-06-10
SI21353A (en) 2004-06-30
AU2003302380A8 (en) 2004-06-18
AU2003302380A1 (en) 2004-06-18

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