WO2004044589A3 - Agents diagnostiques et therapeutiques destines a des maladies associees au recepteur 3 couple a une proteine g sphingolipide de differenciation endotheliale humain (edg3) - Google Patents
Agents diagnostiques et therapeutiques destines a des maladies associees au recepteur 3 couple a une proteine g sphingolipide de differenciation endotheliale humain (edg3) Download PDFInfo
- Publication number
- WO2004044589A3 WO2004044589A3 PCT/EP2003/012120 EP0312120W WO2004044589A3 WO 2004044589 A3 WO2004044589 A3 WO 2004044589A3 EP 0312120 W EP0312120 W EP 0312120W WO 2004044589 A3 WO2004044589 A3 WO 2004044589A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- diseases
- edg3
- sphingolipid
- therapeutics
- diagnostics
- Prior art date
Links
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 7
- 201000010099 disease Diseases 0.000 title abstract 3
- 108020001289 G protein-coupled receptor 3 Proteins 0.000 title 1
- 102100033047 G-protein coupled receptor 3 Human genes 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 230000009762 endothelial cell differentiation Effects 0.000 title 1
- 150000003408 sphingolipids Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 208000024172 Cardiovascular disease Diseases 0.000 abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 2
- 201000011510 cancer Diseases 0.000 abstract 2
- 210000003169 central nervous system Anatomy 0.000 abstract 2
- 208000035475 disorder Diseases 0.000 abstract 2
- 208000014951 hematologic disease Diseases 0.000 abstract 2
- 230000002093 peripheral effect Effects 0.000 abstract 2
- 210000001428 peripheral nervous system Anatomy 0.000 abstract 2
- 101100255990 Homo sapiens S1PR3 gene Proteins 0.000 abstract 1
- 101000693269 Homo sapiens Sphingosine 1-phosphate receptor 3 Proteins 0.000 abstract 1
- 102100025747 Sphingosine 1-phosphate receptor 3 Human genes 0.000 abstract 1
- 238000003556 assay Methods 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Endocrinology (AREA)
- Food Science & Technology (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2003287976A AU2003287976A1 (en) | 2002-11-13 | 2003-10-31 | Diagnostics and therapeutics for diseases associated with human endothelial differentiation, sphingolipid g-protein-coupled receptor 3 (edg3) |
EP03779825A EP1597582A2 (fr) | 2002-11-13 | 2003-10-31 | Agents diagnostiques et therapeutiques destines a des maladies associees au recepteur 3 couple a une proteine g sphingolipide de differenciation endotheliale humain (edg3) |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP02025501 | 2002-11-13 | ||
EP02025501.4 | 2002-11-13 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2004044589A2 WO2004044589A2 (fr) | 2004-05-27 |
WO2004044589A3 true WO2004044589A3 (fr) | 2004-06-17 |
Family
ID=32309334
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP2003/012120 WO2004044589A2 (fr) | 2002-11-13 | 2003-10-31 | Agents diagnostiques et therapeutiques destines a des maladies associees au recepteur 3 couple a une proteine g sphingolipide de differenciation endotheliale humain (edg3) |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP1597582A2 (fr) |
AU (1) | AU2003287976A1 (fr) |
WO (1) | WO2004044589A2 (fr) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20120071448A1 (en) * | 2009-05-05 | 2012-03-22 | Allergan, Inc. | S1P3 Receptor Inhibitors for Treating Conditions of the Eye |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6130067A (en) * | 1998-05-20 | 2000-10-10 | Smithkline Beecham Corporation | Human EDG3sb gene |
-
2003
- 2003-10-31 EP EP03779825A patent/EP1597582A2/fr not_active Withdrawn
- 2003-10-31 WO PCT/EP2003/012120 patent/WO2004044589A2/fr not_active Application Discontinuation
- 2003-10-31 AU AU2003287976A patent/AU2003287976A1/en not_active Abandoned
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6130067A (en) * | 1998-05-20 | 2000-10-10 | Smithkline Beecham Corporation | Human EDG3sb gene |
Non-Patent Citations (5)
Title |
---|
DATABASE EMBL 20 May 2001 (2001-05-20), Database accession no. AR112475 * |
MAZURAI D. ET AL: "Cell type-specific localization of human cardiac S1P receptors", JOURNAL OF HISTOCHEMISTRY AND CYTOCHEMISTRY, vol. 50, no. 5, May 2002 (2002-05-01), pages 661 - 669, XP009029256 * |
PYNE S ET AL: "REVIEW ARTICLE SPHINGOSINE 1-PHOSPHATE SIGNALLING IN MAMMALIAN CELLS", BIOCHEMICAL JOURNAL, THE BIOCHEMICAL SOCIETY, LONDON, GB, vol. 349, 2000, pages 385 - 402, XP000939036, ISSN: 0264-6021 * |
RACKE K ET AL: "Potential role of EDG receptors and lysophospholipids as their endogenous ligands in the respiratory tract", PULMONARY PHARMACOLOGY AND THERAPEUTICS, vol. 13, no. 3, 2000, &, pages 99 - 114, XP002277298, ISSN: 1094-5539 * |
ZHANG G ET AL: "Comparative analysis of three murine G-protein coupled receptors activated by sphingosine-1-phosphate", GENE, ELSEVIER BIOMEDICAL PRESS. AMSTERDAM, NL, vol. 227, no. 1, 4 February 1999 (1999-02-04), pages 89 - 99, XP004155772, ISSN: 0378-1119 * |
Also Published As
Publication number | Publication date |
---|---|
AU2003287976A1 (en) | 2004-06-03 |
EP1597582A2 (fr) | 2005-11-23 |
WO2004044589A2 (fr) | 2004-05-27 |
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