+

WO2003102164A3 - Cancer-linked gene as target for chemotherapy - Google Patents

Cancer-linked gene as target for chemotherapy

Info

Publication number
WO2003102164A3
WO2003102164A3 PCT/US2003/017920 US0317920W WO03102164A3 WO 2003102164 A3 WO2003102164 A3 WO 2003102164A3 US 0317920 W US0317920 W US 0317920W WO 03102164 A3 WO03102164 A3 WO 03102164A3
Authority
WO
WIPO (PCT)
Prior art keywords
cancer
target
disclosed
chemotherapy
linked gene
Prior art date
Application number
PCT/US2003/017920
Other languages
French (fr)
Other versions
WO2003102164A2 (en
Inventor
Martin Shea
Reinhard Ebner
Original Assignee
Avalon Pharmaceuticals
Martin Shea
Reinhard Ebner
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Avalon Pharmaceuticals, Martin Shea, Reinhard Ebner filed Critical Avalon Pharmaceuticals
Priority to AU2003240572A priority Critical patent/AU2003240572A1/en
Publication of WO2003102164A2 publication Critical patent/WO2003102164A2/en
Publication of WO2003102164A3 publication Critical patent/WO2003102164A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Cancer-linked gene sequences, and derived amino acid sequences, are disclosed along with processes for assaying potential antitumor agents based on their modulation of the expression of these cancer-linked genes. Also disclosed are antibodies that react with the disclosed polypeptides and methods of using the antibodies to treat cancerous conditions, such as by using the antibody to target cancerous cells in vivo for purposes of delivering therapeutic agents thereto. Also described are methods of diagnosing using the gene sequences.
PCT/US2003/017920 2002-05-30 2003-05-29 Cancer-linked gene as target for chemotherapy WO2003102164A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2003240572A AU2003240572A1 (en) 2002-05-30 2003-05-29 Cancer-linked gene as target for chemotherapy

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US38436702P 2002-05-30 2002-05-30
US60/384,367 2002-05-30

Publications (2)

Publication Number Publication Date
WO2003102164A2 WO2003102164A2 (en) 2003-12-11
WO2003102164A3 true WO2003102164A3 (en) 2005-04-21

Family

ID=29712020

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2003/017920 WO2003102164A2 (en) 2002-05-30 2003-05-29 Cancer-linked gene as target for chemotherapy

Country Status (2)

Country Link
AU (1) AU2003240572A1 (en)
WO (1) WO2003102164A2 (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000058473A2 (en) * 1999-03-31 2000-10-05 Curagen Corporation Nucleic acids including open reading frames encoding polypeptides; 'orfx'

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000058473A2 (en) * 1999-03-31 2000-10-05 Curagen Corporation Nucleic acids including open reading frames encoding polypeptides; 'orfx'

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
DATABASE GENBANK [online] 29 January 2002 (2002-01-29), KIKUNO R. ET AL: "Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro", XP002903261, Database accession no. (AB028982) *
DATABASE GENBANK [online] 8 February 2001 (2001-02-08), SHIMKETS RA ET AL: "Novel nucleic acids and peptides derived from open reading frame X, useful for treating e.g. cancers, proliferative disorders, neurodegenerative disorders and cardiovascular disease", XP002903260, Database accession no. (AAC76569) *
DNA RES., vol. 6, no. 3, 1999, pages 197 - 205 *
HAMPE ET AL: "The genes for the human VPS10 domain-containing receptors are large and contain many small exons", HUMAN GENETICS, vol. 108, no. 6, 2001, pages 529 - 536, XP002294173 *
KIKUNO R. ET AL: "Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro", DNA RESEARCH, vol. 6, no. 3, 1999, pages 197 - 205, XP002952960 *

Also Published As

Publication number Publication date
WO2003102164A2 (en) 2003-12-11
AU2003240572A8 (en) 2003-12-19
AU2003240572A1 (en) 2003-12-19

Similar Documents

Publication Publication Date Title
WO2003097803A3 (en) Cancer-linked gene as target for chemotherapy
WO2003101400A3 (en) Cancer-linked gene as target for chemotherapy
WO2003105758A3 (en) Cancer-linked gene as target for chemotherapy
WO2003104399A3 (en) Cancer-linked gene as target for chemotherapy
WO2008020596A3 (en) Treating or preventing cancers over-expressing reg4 or kiaa0101
WO2007113648A3 (en) Ctla4 antibody combination therapy
WO2004046342A3 (en) Novel gene targets and ligands that bind thereto for treatment and diagnosis of carcinomas
WO2005077091A3 (en) Nicotinamide riboside kinase compositions and methods for using the same
WO2004031231A3 (en) Genes and polypeptides relating to prostate cancers
WO2003066663A3 (en) Peptides for recognition and targeting of glial cell tumors
WO2004078215A3 (en) Use of antibody conjugated deoxycytidine kinase for adept
WO2004037198A3 (en) Antibody-mediated induction of tumor cell death
WO2003076579A3 (en) Cancer-linked gene as target for chemotherapy
WO2002031198A3 (en) Cancer-linked genes as targets for chemotherapy
WO2003104401A3 (en) Cancer-linked gene as target for chemotherapy
WO2003104438A3 (en) Cancer-linked gene as target for chemotherapy
WO2003097802A3 (en) Cancer-linked gene as target for chemotherapy
WO2004033485A3 (en) Nucleic acid supported protein complementation
WO2004026238A8 (en) Immunotherapeutic compositions and methods for the treatment of moderately to well-differentiated cancers
WO2005062788A3 (en) Prostate specific proteins expressed in cancer and methods of use thereof
WO2003076587A3 (en) Cancer-linked gene as target for chemotherapy
WO2005035724A3 (en) Cancer-linked genes as targets for chemotherapy
WO2003105783A3 (en) Cancer-linked gene as target for chemotherapy
WO2005019475A3 (en) Hypoxia-inducible protein 2 (hig2), a novel therapeutic potential target of renal cell carcinoma (rcc)
WO2003097801A3 (en) Cancer-linked gene as target for chemotherapy

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NI NO NZ OM PH PL PT RO RU SC SD SE SG SK SL TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LU MC NL PT RO SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
122 Ep: pct application non-entry in european phase
NENP Non-entry into the national phase

Ref country code: JP

WWW Wipo information: withdrawn in national office

Country of ref document: JP

点击 这是indexloc提供的php浏览器服务，不要输入任何密码和下载