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WO2003035862A3 - Regulation of human arginase signature-containing protein - Google Patents

Regulation of human arginase signature-containing protein Download PDF

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Publication number
WO2003035862A3
WO2003035862A3 PCT/EP2002/011947 EP0211947W WO03035862A3 WO 2003035862 A3 WO2003035862 A3 WO 2003035862A3 EP 0211947 W EP0211947 W EP 0211947W WO 03035862 A3 WO03035862 A3 WO 03035862A3
Authority
WO
WIPO (PCT)
Prior art keywords
signature
containing protein
human arginase
regulation
reagents
Prior art date
Application number
PCT/EP2002/011947
Other languages
French (fr)
Other versions
WO2003035862A2 (en
Inventor
Timothy J Smith
Original Assignee
Bayer Healthcare Ag
Timothy J Smith
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Healthcare Ag, Timothy J Smith filed Critical Bayer Healthcare Ag
Publication of WO2003035862A2 publication Critical patent/WO2003035862A2/en
Publication of WO2003035862A3 publication Critical patent/WO2003035862A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Reagents that regulate human arginase signature-containing protein and reagents which bind to human arginase signature-containing protein gene products can play a role in preventing, ameliorating, or correcting dysfunctions or diseases including, but not limited to, cardiovascular disorders.
PCT/EP2002/011947 2001-10-26 2002-10-25 Regulation of human arginase signature-containing protein WO2003035862A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33062001P 2001-10-26 2001-10-26
US60/330,620 2001-10-26

Publications (2)

Publication Number Publication Date
WO2003035862A2 WO2003035862A2 (en) 2003-05-01
WO2003035862A3 true WO2003035862A3 (en) 2003-12-24

Family

ID=23290550

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2002/011947 WO2003035862A2 (en) 2001-10-26 2002-10-25 Regulation of human arginase signature-containing protein

Country Status (1)

Country Link
WO (1) WO2003035862A2 (en)

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL [online] 11 November 2000 (2000-11-11), "Homo sapiens mRNA for KIAA1173 protein, complete cds", XP002246960, retrieved from EBI Database accession no. AB042554 *
DATABASE EMBL [online] 13 February 2002 (2002-02-13), DRMANAC ET AL: "New isolated polynucleotide...", XP002246986, retrieved from EBI Database accession no. ABG04239 *
DATABASE SWISS-PROT [online] EBI; July 1998 (1998-07-01), "Arginase family signature 1", XP002246961, Database accession no. PS00147 *
DATABASE SWISS-PROT [online] EBI; July 1998 (1998-07-01), "Arginase family signature 2", XP002246962, Database accession no. PS00148 *
DATABASE SWISS-PROT [online] EBI; July 1998 (1998-07-01), "Arginase family signature 3", XP002246963, Database accession no. PS01053 *
LI ET AL: "Regulatory role of arginase I and II in nitric oxide, polyamine, and proline syntheses in endothelial cells", AM J PHYSIOL ENDOCRINOL METAB, vol. 280, January 2001 (2001-01-01), pages E75 - E82, XP002246959 *

Also Published As

Publication number Publication date
WO2003035862A2 (en) 2003-05-01

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