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WO2003035683A3 - Surfactant protein-d and atherosclerosis - Google Patents

Surfactant protein-d and atherosclerosis Download PDF

Info

Publication number
WO2003035683A3
WO2003035683A3 PCT/DK2002/000711 DK0200711W WO03035683A3 WO 2003035683 A3 WO2003035683 A3 WO 2003035683A3 DK 0200711 W DK0200711 W DK 0200711W WO 03035683 A3 WO03035683 A3 WO 03035683A3
Authority
WO
WIPO (PCT)
Prior art keywords
atherosclerosis
surfactant protein
vitro
assay
detect
Prior art date
Application number
PCT/DK2002/000711
Other languages
French (fr)
Other versions
WO2003035683A8 (en
WO2003035683A2 (en
Inventor
Uffe Holmskov
Grith Lykke Soerensen
Jens Madsen
Ida Tornoe
Original Assignee
Uffe Holmskov
Grith Lykke Soerensen
Jens Madsen
Ida Tornoe
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Uffe Holmskov, Grith Lykke Soerensen, Jens Madsen, Ida Tornoe filed Critical Uffe Holmskov
Priority to AU2002350409A priority Critical patent/AU2002350409A1/en
Publication of WO2003035683A2 publication Critical patent/WO2003035683A2/en
Publication of WO2003035683A3 publication Critical patent/WO2003035683A3/en
Publication of WO2003035683A8 publication Critical patent/WO2003035683A8/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/785—Alveolar surfactant peptides; Pulmonary surfactant peptides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54386—Analytical elements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/785—Alveolar surfactant peptides; Pulmonary surfactant peptides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/32—Cardiovascular disorders
    • G01N2800/323—Arteriosclerosis, Stenosis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/50—Determining the risk of developing a disease

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pulmonology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The invention describes a novel form of surfactant protein D (SP-D). It discloses a specific in vitro SP-D assay and a method to detect an increased risk for the development of atherosclerosis.
PCT/DK2002/000711 2001-10-26 2002-10-25 Surfactant protein-d and atherosclerosis WO2003035683A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002350409A AU2002350409A1 (en) 2001-10-26 2002-10-25 Surfactant protein-d and atherosclerosis

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US33066401P 2001-10-26 2001-10-26
US60/330,664 2001-10-26
US34237201P 2001-12-27 2001-12-27
US60/342,372 2001-12-27

Publications (3)

Publication Number Publication Date
WO2003035683A2 WO2003035683A2 (en) 2003-05-01
WO2003035683A3 true WO2003035683A3 (en) 2004-03-04
WO2003035683A8 WO2003035683A8 (en) 2004-04-08

Family

ID=26987389

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/DK2002/000711 WO2003035683A2 (en) 2001-10-26 2002-10-25 Surfactant protein-d and atherosclerosis

Country Status (2)

Country Link
AU (1) AU2002350409A1 (en)
WO (1) WO2003035683A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20200081438A (en) 2017-10-31 2020-07-07 웨스턴 온콜리틱스 리미티드 Platform oncolytic vector for systemic delivery
AU2022265689A1 (en) 2021-04-30 2023-10-19 Kalivir Immunotherapeutics, Inc. Oncolytic viruses for modified mhc expression
CA3221664A1 (en) * 2021-06-17 2022-12-22 Stephen Howard Thorne Tnfsf-l fusion proteins and uses thereof

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997035619A1 (en) * 1996-03-28 1997-10-02 Genitrix, L.L.C. Opsonin-enhanced cells, and methods of modulating an immune response to an antigen
WO1999050286A2 (en) * 1998-03-31 1999-10-07 University Of Cincinnati Antioxidant peptides derived from apolipoprotein a-iv
WO2000055180A2 (en) * 1999-03-12 2000-09-21 Human Genome Sciences, Inc. Human lung cancer associated gene sequences and polypeptides
WO2002006301A2 (en) * 2000-06-30 2002-01-24 University Of Cincinnati Peptides with antioxidant and antimicrobial properties

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997035619A1 (en) * 1996-03-28 1997-10-02 Genitrix, L.L.C. Opsonin-enhanced cells, and methods of modulating an immune response to an antigen
WO1999050286A2 (en) * 1998-03-31 1999-10-07 University Of Cincinnati Antioxidant peptides derived from apolipoprotein a-iv
WO2000055180A2 (en) * 1999-03-12 2000-09-21 Human Genome Sciences, Inc. Human lung cancer associated gene sequences and polypeptides
WO2000055173A1 (en) * 1999-03-12 2000-09-21 Human Genome Sciences, Inc. Human breast and ovarian cancer associated gene sequences and polypeptides
WO2002006301A2 (en) * 2000-06-30 2002-01-24 University Of Cincinnati Peptides with antioxidant and antimicrobial properties

Non-Patent Citations (8)

* Cited by examiner, † Cited by third party
Title
BRIDGES J P ET AL: "Pulmonary surfactant proteins A and D are potent endogenous inhibitors of lipid peroxidation and oxidative cellular injury.", THE JOURNAL OF BIOLOGICAL CHEMISTRY. UNITED STATES 8 DEC 2000, vol. 275, no. 49, 8 December 2000 (2000-12-08), pages 38848 - 38855, XP002235424, ISSN: 0021-9258 *
DATABASE EMBL [online] 12 July 1999 (1999-07-12), XP002235563, retrieved from EBI Database accession no. AI820677 *
DATABASE EMBL [online] 12 November 1992 (1992-11-12), XP002235562, retrieved from EBI Database accession no. HSSPD03 *
DATABASE EMBL [online] 14 March 2001 (2001-03-14), XP002902883, retrieved from EBI Database accession no. AAB58124 *
DATABASE EMBL [online] 2 August 1999 (1999-08-02), XP002235564, retrieved from EBI Database accession no. AI924488 *
DATABASE EMBL [online] 21 May 2002 (2002-05-21), XP002902884, retrieved from EBI Database accession no. AAU76474 *
DATABASE EMBL [online] 21 May 2002 (2002-05-21), XP002902885, retrieved from EBI Database accession no. AAU76475 *
SHUICHI KAMADA ET AL: "A sandwich enzyme immunoassay for pulmonary surfactant protein D and measurement of its blood levels in drowning victims", FORENSIC SCIENCE INTERNATIONAL, vol. 109, 2000, pages 51 - 63, XP002264884 *

Also Published As

Publication number Publication date
AU2002350409A1 (en) 2003-05-06
WO2003035683A8 (en) 2004-04-08
WO2003035683A2 (en) 2003-05-01

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