+

WO2003035233A1 - Dispositif de separation, systeme d'analyse, procede de separation et procede pour produire un dispositif de separation - Google Patents

Dispositif de separation, systeme d'analyse, procede de separation et procede pour produire un dispositif de separation Download PDF

Info

Publication number
WO2003035233A1
WO2003035233A1 PCT/JP2002/011144 JP0211144W WO03035233A1 WO 2003035233 A1 WO2003035233 A1 WO 2003035233A1 JP 0211144 W JP0211144 W JP 0211144W WO 03035233 A1 WO03035233 A1 WO 03035233A1
Authority
WO
WIPO (PCT)
Prior art keywords
separating device
separation
separation method
manufacture
analysis system
Prior art date
Application number
PCT/JP2002/011144
Other languages
English (en)
French (fr)
Inventor
Kazuhiro Iida
Noriyuki Iguchi
Masakazu Baba
Hiroko Someya
Hisao Kawaura
Toru Sano
Toshikazu Sakamoto
Original Assignee
Nec Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nec Corporation filed Critical Nec Corporation
Priority to CA002465099A priority Critical patent/CA2465099A1/en
Priority to EP02775403A priority patent/EP1457251A4/en
Priority to US10/493,660 priority patent/US20040256318A1/en
Priority to KR10-2004-7006178A priority patent/KR20040048996A/ko
Publication of WO2003035233A1 publication Critical patent/WO2003035233A1/ja

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D69/00—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D67/00—Processes specially adapted for manufacturing semi-permeable membranes for separation processes or apparatus
    • B01D67/0002—Organic membrane manufacture
    • B01D67/0006—Organic membrane manufacture by chemical reactions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D57/00—Separation, other than separation of solids, not fully covered by a single other group or subclass, e.g. B03C
    • B01D57/02—Separation, other than separation of solids, not fully covered by a single other group or subclass, e.g. B03C by electrophoresis
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/14—Ultrafiltration; Microfiltration
    • B01D61/18—Apparatus therefor
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/24—Dialysis ; Membrane extraction
    • B01D61/28—Apparatus therefor
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D67/00—Processes specially adapted for manufacturing semi-permeable membranes for separation processes or apparatus
    • B01D67/0002—Organic membrane manufacture
    • B01D67/0023—Organic membrane manufacture by inducing porosity into non porous precursor membranes
    • B01D67/0032—Organic membrane manufacture by inducing porosity into non porous precursor membranes by elimination of segments of the precursor, e.g. nucleation-track membranes, lithography or laser methods
    • B01D67/0034—Organic membrane manufacture by inducing porosity into non porous precursor membranes by elimination of segments of the precursor, e.g. nucleation-track membranes, lithography or laser methods by micromachining techniques, e.g. using masking and etching steps, photolithography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D67/00—Processes specially adapted for manufacturing semi-permeable membranes for separation processes or apparatus
    • B01D67/0039—Inorganic membrane manufacture
    • B01D67/0053—Inorganic membrane manufacture by inducing porosity into non porous precursor membranes
    • B01D67/0058—Inorganic membrane manufacture by inducing porosity into non porous precursor membranes by selective elimination of components, e.g. by leaching
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D67/00—Processes specially adapted for manufacturing semi-permeable membranes for separation processes or apparatus
    • B01D67/0039—Inorganic membrane manufacture
    • B01D67/0053—Inorganic membrane manufacture by inducing porosity into non porous precursor membranes
    • B01D67/006—Inorganic membrane manufacture by inducing porosity into non porous precursor membranes by elimination of segments of the precursor, e.g. nucleation-track membranes, lithography or laser methods
    • B01D67/0065—Inorganic membrane manufacture by inducing porosity into non porous precursor membranes by elimination of segments of the precursor, e.g. nucleation-track membranes, lithography or laser methods by anodic oxidation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D67/00—Processes specially adapted for manufacturing semi-permeable membranes for separation processes or apparatus
    • B01D67/0081—After-treatment of organic or inorganic membranes
    • B01D67/0088—Physical treatment with compounds, e.g. swelling, coating or impregnation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D67/00—Processes specially adapted for manufacturing semi-permeable membranes for separation processes or apparatus
    • B01D67/0081—After-treatment of organic or inorganic membranes
    • B01D67/0093—Chemical modification
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D69/00—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor
    • B01D69/02—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor characterised by their properties
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D71/00—Semi-permeable membranes for separation processes or apparatus characterised by the material; Manufacturing processes specially adapted therefor
    • B01D71/02—Inorganic material
    • B01D71/0213—Silicon
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D71/00—Semi-permeable membranes for separation processes or apparatus characterised by the material; Manufacturing processes specially adapted therefor
    • B01D71/02—Inorganic material
    • B01D71/024—Oxides
    • B01D71/025—Aluminium oxide
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D71/00—Semi-permeable membranes for separation processes or apparatus characterised by the material; Manufacturing processes specially adapted therefor
    • B01D71/02—Inorganic material
    • B01D71/024—Oxides
    • B01D71/027—Silicium oxide
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502753—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by bulk separation arrangements on lab-on-a-chip devices, e.g. for filtration or centrifugation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502761—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads, for physically stretching molecules
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2323/00—Details relating to membrane preparation
    • B01D2323/34—Use of radiation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2325/00—Details relating to properties of membranes
    • B01D2325/36—Hydrophilic membranes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2325/00—Details relating to properties of membranes
    • B01D2325/38—Hydrophobic membranes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/10—Integrating sample preparation and analysis in single entity, e.g. lab-on-a-chip concept
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0681—Filter
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/40—Concentrating samples
    • G01N1/4077—Concentrating samples by other techniques involving separation of suspended solids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/38—Diluting, dispersing or mixing samples
    • G01N2001/383—Diluting, dispersing or mixing samples collecting and diluting in a flow of liquid
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/60—Construction of the column
    • G01N30/6052—Construction of the column body
    • G01N30/6069—Construction of the column body with compartments or bed substructure
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/60—Construction of the column
    • G01N30/6095—Micromachined or nanomachined, e.g. micro- or nanosize

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Manufacturing & Machinery (AREA)
  • Water Supply & Treatment (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Optics & Photonics (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Fluid Mechanics (AREA)
  • Urology & Nephrology (AREA)
  • Electrochemistry (AREA)
  • Environmental & Geological Engineering (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Electrostatic Separation (AREA)
  • Separation Of Solids By Using Liquids Or Pneumatic Power (AREA)
PCT/JP2002/011144 2001-10-26 2002-10-28 Dispositif de separation, systeme d'analyse, procede de separation et procede pour produire un dispositif de separation WO2003035233A1 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
CA002465099A CA2465099A1 (en) 2001-10-26 2002-10-28 Separation device, analysis system, separation method, and method of manufacturing the separation device
EP02775403A EP1457251A4 (en) 2001-10-26 2002-10-28 SEPARATION DEVICE, ANALYSIS SYSTEM, SEPARATION METHOD, AND METHOD FOR PRODUCING SEPARATION DEVICE
US10/493,660 US20040256318A1 (en) 2001-10-26 2002-10-28 Separating device, analysis system separation method and method of manufacture of separating device
KR10-2004-7006178A KR20040048996A (ko) 2001-10-26 2002-10-28 분리장치, 분석 시스템, 분리방법 및 분리장치의 제조방법

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
JP2001328747 2001-10-26
JP2001/328747 2001-10-26
JP2002/140814 2002-05-15
JP2002140814 2002-05-15
JP2002/291465 2002-10-03
JP2002291465A JP2004042012A (ja) 2001-10-26 2002-10-03 分離装置、分析システム、分離方法および分離装置の製造方法

Publications (1)

Publication Number Publication Date
WO2003035233A1 true WO2003035233A1 (fr) 2003-05-01

Family

ID=27347737

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2002/011144 WO2003035233A1 (fr) 2001-10-26 2002-10-28 Dispositif de separation, systeme d'analyse, procede de separation et procede pour produire un dispositif de separation

Country Status (7)

Country Link
US (1) US20040256318A1 (ja)
EP (1) EP1457251A4 (ja)
JP (1) JP2004042012A (ja)
KR (1) KR20040048996A (ja)
CN (1) CN1575198A (ja)
CA (1) CA2465099A1 (ja)
WO (1) WO2003035233A1 (ja)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL1024250C2 (nl) * 2003-09-09 2005-03-10 Fluxxion B V Vervaardiging van een microzeef, en microzeef en inrichting met een microzeef.
WO2005062037A2 (en) * 2003-12-17 2005-07-07 Intel Corporation Sieving media from planar arrays of nanoscale grooves, method of making the same, and method of using the same
US11906490B2 (en) * 2018-08-09 2024-02-20 Kookmin University Industry Academy Cooperation Foundation Micro gas chromatography system

Families Citing this family (59)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003013692A1 (fr) * 2001-08-03 2003-02-20 Nec Corporation Appareil de separation et procede de fabrication d'un appareil de separation
US20060177350A1 (en) * 2003-03-19 2006-08-10 Nec Corporation Microchip, sampling method, sample separating method, sample analyzing method, and sample recovering method
DE10313201A1 (de) * 2003-03-21 2004-10-07 Steag Microparts Gmbh Mikrostrukturierte Trennvorrichtung und mikrofluidisches Verfahren zum Abtrennen von flüssigen Bestandteilen aus einer Flüssigkeit, die Partikel enthält
JP2005007352A (ja) * 2003-06-20 2005-01-13 Sharp Corp 粒子の分離方法及び分離装置並びに検出装置
JP4619728B2 (ja) * 2004-09-02 2011-01-26 株式会社エンプラス 試料分析装置
US20090010673A1 (en) * 2005-01-25 2009-01-08 Nec Corporation Filter and method of manufacturing the same
EP1848986A4 (en) * 2005-01-25 2009-07-29 Massachusetts Inst Technology DEVICE FOR ELECTROKINETIC CONCENTRATION AND USE METHOD THEREFOR
KR100691528B1 (ko) * 2005-06-09 2007-03-09 강원대학교산학협력단 단백질 칩 분석용 표면 플라즈몬 주사 현미경 장치
JP2007175684A (ja) * 2005-12-26 2007-07-12 Minoru Seki 微粒子の濃縮・分級のための流路構造および方法
CN101410753A (zh) * 2006-03-29 2009-04-15 陶氏康宁公司 使用软光刻法形成纳米级特征的方法
JP2007309741A (ja) * 2006-05-17 2007-11-29 Olympus Corp 血液分離方法および血液分離装置
EP2040843B1 (en) * 2006-06-01 2020-02-26 The Trustees of Princeton University Apparatus for continuous particle separation
WO2008063135A1 (en) * 2006-11-24 2008-05-29 Agency For Science, Technology And Research Apparatus for processing a sample in a liquid droplet and method of using the same
KR100818290B1 (ko) * 2006-12-11 2008-03-31 삼성전자주식회사 성분 분리 장치 및 성분 분리 방법
US20090321364A1 (en) * 2007-04-20 2009-12-31 Cambrios Technologies Corporation Systems and methods for filtering nanowires
JP5018879B2 (ja) * 2007-05-15 2012-09-05 パナソニック株式会社 成分分離デバイス
KR20100087130A (ko) * 2007-09-26 2010-08-03 메사추세츠 인스티튜트 오브 테크놀로지 전기역학적 농축 장치 및 그의 사용 방법
US8075468B2 (en) 2008-02-27 2011-12-13 Fenwal, Inc. Systems and methods for mid-processing calculation of blood composition
US8685258B2 (en) 2008-02-27 2014-04-01 Fenwal, Inc. Systems and methods for conveying multiple blood components to a recipient
JP2010071857A (ja) * 2008-09-19 2010-04-02 Sekisui Chem Co Ltd 血漿分離装置
JP5141919B2 (ja) * 2009-09-08 2013-02-13 セイコーエプソン株式会社 細胞処理デバイス、細胞処理カートリッジおよび体液処理システム
EP2316565A1 (en) * 2009-10-26 2011-05-04 Fei Company A micro-reactor for observing particles in a fluid
JP5624629B2 (ja) * 2009-12-23 2014-11-12 サイトベラ，インコーポレイテッド 粒子を濾過するためのシステム及び方法
DE102010032203A1 (de) * 2010-07-26 2012-01-26 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Verfahren und Vorrichtung zur passiven Trennung und Sortierung von Tropfen, insbesondere in einem mikrofluidischen System, durch Verwendung von nicht-optischen Markern für Reaktionen innerhalb der Tropfen
US8480978B2 (en) * 2010-08-12 2013-07-09 University Of Southern California Microfluidic fluid separator and related methods
WO2012025343A1 (en) * 2010-08-24 2012-03-01 Unilever Nv Water purification device comprising a gravity- fed filter
KR101260455B1 (ko) * 2011-07-21 2013-05-07 포항공과대학교 산학협력단 극소수성 표면 가공 방법 및 극소수성 표면을 가지는 증발기
KR101211862B1 (ko) 2012-04-30 2012-12-12 한국기계연구원 자기장을 이용하는 자가 세포 추출장치 및 이를 이용하는 방법
US20150191772A1 (en) * 2012-06-29 2015-07-09 Danmarks Tekniske Universitet Method of charging a test carrier and a test carrier
US10603419B2 (en) * 2013-01-11 2020-03-31 The Charles Stark Draper Laboratories, Inc. Systems and methods for increasing convective clearance of undesired particles in a microfluidic device
US10478543B2 (en) * 2013-01-11 2019-11-19 The Charles Stark Draper Laboratory, Inc. Systems and methods for increasing convective clearance of undesired particles in a microfluidic device
US10342909B2 (en) * 2013-01-11 2019-07-09 The Charles Stark Draper Laboratory Inc. Systems and methods for increasing convective clearance of undesired particles in a microfluidic device
US20150375228A1 (en) * 2013-03-15 2015-12-31 The Regents Of The University Of California Devices for sorting cells in a sample and methods for use thereof
KR20150014781A (ko) 2013-07-30 2015-02-09 삼성전자주식회사 유체를 여과하기 위한 장치 및 그를 이용한 입자를 분리하는 방법
NO342032B1 (no) 2013-10-25 2018-03-12 Trilobite Innovation As Fluidraffineringsanordning og -sammenstilling
KR102365795B1 (ko) * 2014-01-20 2022-02-21 핼시언 바이오메디컬, 인코퍼레이티드 입자의 분리 및 농축
AU2015271807A1 (en) * 2014-06-02 2017-01-05 University Of Maryland, College Park Device and methods of using device for separation of bacteria from complex samples
JP6543927B2 (ja) * 2014-12-22 2019-07-17 株式会社リコー 液滴形成装置
US10376898B2 (en) 2015-06-12 2019-08-13 Dow Global Technologies Llc Method for manufacturing high aspect ratio silver nanowires
US10081020B2 (en) 2015-06-12 2018-09-25 Dow Global Technologies Llc Hydrothermal method for manufacturing filtered silver nanowires
JP6620504B2 (ja) * 2015-10-16 2019-12-18 ウシオ電機株式会社 吸光度測定装置および吸光度測定方法
JP6729027B2 (ja) * 2016-06-15 2020-07-22 ウシオ電機株式会社 マイクロ流路チップ
JP6729026B2 (ja) * 2016-06-15 2020-07-22 ウシオ電機株式会社 マイクロ流路チップおよび検体濃度測定装置
WO2018013135A1 (en) 2016-07-15 2018-01-18 Hewlett-Packard Development Company, L.P. Microfluidic filtering system
US11904294B2 (en) * 2018-01-15 2024-02-20 Panasonic Intellectual Property Management Co., Ltd. Concentration device
WO2019138784A1 (ja) * 2018-01-15 2019-07-18 パナソニックＩｐマネジメント株式会社 濃縮デバイス及び濃縮・分離装置
KR102019664B1 (ko) * 2018-04-18 2019-09-09 포항공과대학교 산학협력단 이동 속도 차이를 이용한 세포 구분 방법, 이를 수행하기 위한 장치
CN108745428B (zh) * 2018-06-05 2020-11-27 合肥工业大学 一种多通道三维微流控纸芯片及其制备方法
CN112867566A (zh) 2018-10-23 2021-05-28 三叶虫创新股份有限公司 流体提纯装置
WO2020102533A1 (en) * 2018-11-15 2020-05-22 Massachusetts Institute Of Technology Multi-dimensional double spiral device and methods of use thereof
CN113164953B (zh) * 2018-11-21 2023-07-21 Bvw控股公司 微结构化区分装置
JP7287622B2 (ja) * 2018-12-14 2023-06-06 オルガノ株式会社 水質測定装置、および水質測定方法
JP7417294B2 (ja) * 2019-04-04 2024-01-18 国立大学法人千葉大学 クロスフローろ過装置
CN112574851B (zh) * 2019-09-30 2022-10-11 上海傲睿科技有限公司 一种单细胞筛选器、筛选组件、筛选方法及应用
JP2021060239A (ja) * 2019-10-04 2021-04-15 国立研究開発法人産業技術総合研究所 濃縮装置
CN111207988B (zh) * 2020-02-18 2021-08-27 中南大学 一种基于微流体的矿浆监测装置
CN113624831B (zh) * 2021-08-05 2024-05-10 广东农工商职业技术学院 一种分离富集沉积物有机氮并测定同位素和含量的方法
WO2023041948A1 (en) * 2021-09-15 2023-03-23 Fundación Para La Investigación Médica Aplicada Device suitable for exchanging a liquid medium and selecting particles in a mixture
CN114656093B (zh) * 2022-04-22 2023-04-07 倍杰特集团股份有限公司 一种焦化废水零排放预处理装置及方法

Citations (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5329994A (en) * 1976-09-01 1978-03-20 Kuraray Co Ltd Continuous reaction using enzymes or microorganisms
JPS6332478A (ja) * 1986-07-28 1988-02-12 Natl Food Res Inst 酵素反応装置
JPH0523547A (ja) * 1991-07-19 1993-02-02 Nissin Electric Co Ltd 溶液濃縮装置
JPH06254362A (ja) * 1993-03-09 1994-09-13 Rengo Co Ltd 分離膜
EP0701857A1 (en) * 1994-09-14 1996-03-20 Bend Research, Inc. Membrane dehydration of vaporous feeds by countercurrent condensable sweep
WO1996012540A1 (en) * 1994-10-22 1996-05-02 Central Research Laboratories Limited Method and apparatus for diffusive transfer between immiscible fluids
JPH1085568A (ja) * 1996-09-10 1998-04-07 Tonen Corp ガス分離装置
JPH10296060A (ja) * 1997-04-25 1998-11-10 Japan Organo Co Ltd 分離膜の汚染防止方法
JPH10318982A (ja) * 1997-05-22 1998-12-04 Olympus Optical Co Ltd 電気泳動装置
WO1999050436A1 (en) * 1998-03-31 1999-10-07 Roche Diagnostics Gmbh Method of preparing polypeptides in cell-free system and device for its realization
JP2000105219A (ja) * 1998-09-30 2000-04-11 Sanyo Electric Co Ltd 核酸電気泳動装置
JP2000262871A (ja) * 1999-01-11 2000-09-26 Kawamura Inst Of Chem Res 微小膜分離デバイス及びその製造方法
JP2000298109A (ja) * 1999-04-13 2000-10-24 Kanagawa Acad Of Sci & Technol マイクロチャンネル構造体

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2607393B1 (fr) * 1986-11-28 1997-01-24 Hospal Ind Rein artificiel a taux d'echanges moderes
WO1997000121A1 (en) * 1995-06-16 1997-01-03 The University Of Washington Tangential flow planar microfabricated fluid filter
US6090251A (en) * 1997-06-06 2000-07-18 Caliper Technologies, Inc. Microfabricated structures for facilitating fluid introduction into microfluidic devices
US6766817B2 (en) * 2001-07-25 2004-07-27 Tubarc Technologies, Llc Fluid conduction utilizing a reversible unsaturated siphon with tubarc porosity action
US7743928B2 (en) * 2002-09-07 2010-06-29 Timothy Crowley Integrated apparatus and methods for treating liquids

Patent Citations (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5329994A (en) * 1976-09-01 1978-03-20 Kuraray Co Ltd Continuous reaction using enzymes or microorganisms
JPS6332478A (ja) * 1986-07-28 1988-02-12 Natl Food Res Inst 酵素反応装置
JPH0523547A (ja) * 1991-07-19 1993-02-02 Nissin Electric Co Ltd 溶液濃縮装置
JPH06254362A (ja) * 1993-03-09 1994-09-13 Rengo Co Ltd 分離膜
EP0701857A1 (en) * 1994-09-14 1996-03-20 Bend Research, Inc. Membrane dehydration of vaporous feeds by countercurrent condensable sweep
WO1996012540A1 (en) * 1994-10-22 1996-05-02 Central Research Laboratories Limited Method and apparatus for diffusive transfer between immiscible fluids
JPH1085568A (ja) * 1996-09-10 1998-04-07 Tonen Corp ガス分離装置
JPH10296060A (ja) * 1997-04-25 1998-11-10 Japan Organo Co Ltd 分離膜の汚染防止方法
JPH10318982A (ja) * 1997-05-22 1998-12-04 Olympus Optical Co Ltd 電気泳動装置
WO1999050436A1 (en) * 1998-03-31 1999-10-07 Roche Diagnostics Gmbh Method of preparing polypeptides in cell-free system and device for its realization
JP2000105219A (ja) * 1998-09-30 2000-04-11 Sanyo Electric Co Ltd 核酸電気泳動装置
JP2000262871A (ja) * 1999-01-11 2000-09-26 Kawamura Inst Of Chem Res 微小膜分離デバイス及びその製造方法
JP2000298109A (ja) * 1999-04-13 2000-10-24 Kanagawa Acad Of Sci & Technol マイクロチャンネル構造体

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP1457251A4 *

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL1024250C2 (nl) * 2003-09-09 2005-03-10 Fluxxion B V Vervaardiging van een microzeef, en microzeef en inrichting met een microzeef.
WO2005023404A3 (en) * 2003-09-09 2005-05-19 Fluxxion B V Manufacture of a microsieve and apparatus comprising a microsieve
WO2005062037A2 (en) * 2003-12-17 2005-07-07 Intel Corporation Sieving media from planar arrays of nanoscale grooves, method of making the same, and method of using the same
WO2005062037A3 (en) * 2003-12-17 2005-10-27 Intel Corp Sieving media from planar arrays of nanoscale grooves, method of making the same, and method of using the same
US7906026B2 (en) 2003-12-17 2011-03-15 Intel Corporation Sieving media from planar arrays of nanoscale grooves, method of making and method of using the same
US11906490B2 (en) * 2018-08-09 2024-02-20 Kookmin University Industry Academy Cooperation Foundation Micro gas chromatography system

Also Published As

Publication number Publication date
CA2465099A1 (en) 2003-05-01
EP1457251A4 (en) 2005-10-19
JP2004042012A (ja) 2004-02-12
CN1575198A (zh) 2005-02-02
US20040256318A1 (en) 2004-12-23
EP1457251A1 (en) 2004-09-15
KR20040048996A (ko) 2004-06-10

Similar Documents

Publication Publication Date Title
WO2003035233A1 (fr) Dispositif de separation, systeme d'analyse, procede de separation et procede pour produire un dispositif de separation
CN101506647B (zh) 电动浓缩设备及其使用方法
DE602004024186D1 (de) Isolierung und anreicherung fötaler zellen
EP4477758A3 (en) Analysis of multiple analytes using a single assay
WO2004064972A3 (en) Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions
WO2003077851A3 (en) Compounds and methods for analyzing the proteome
EP2053406A3 (en) Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions
AU2002320507A1 (en) Microfluidic devices and systems for separating components of a mixture
WO2008052138A3 (en) Inline-injection microdevice and microfabricated integrated dna analysis system using same
WO2003070898A3 (en) Selective extraction of dna from groups of cells
WO2007065025A3 (en) Method of dna analysis using micro/nanochannel
WO2001071732A3 (en) Porous ferro- or ferrimagnetic glass particles for isolating molecules
WO2002079490A3 (en) Bio-barcodes based on oligonucleotide-modified particles
CA2095591A1 (en) Device and method for moving a target-bearing solid through a liquid for detection while being contained
WO2003019172A3 (en) Apparatus and method for separating an analyte
WO2007035585A3 (en) Systems and methods for enrichment of analytes
WO2003052141A3 (en) High troughput analysis and detection of multiple target sequences using circular probes
WO2019143943A3 (en) Composition and method for concentration and enrichment of nucleic acids
DK1187840T3 (da) Fremgangsmåder til DNA-oprensning
WO2005045075A3 (en) Sample preparation methods and devices
ATE307649T1 (de) Kontinuierliches verfahren zur trennung von stoffen nach molekülgrösse
WO2001059460A3 (en) Mapping of differential display of proteins
WO2007024825A3 (en) Immunoaffinity separation and analysis compositions and methods
WO2005083426A3 (en) Method, chip, device and integrated system for detection biological particles
WO2003056335A3 (de) Mikrovertiefungsarray zur grössenabhängigen sortierung oder separation von in einer strömenden flüssigkeit suspendierten zellen und verfahren zur untersuchung der funktionellen aktivität von einzelzellen

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A1

Designated state(s): CA CN KR US

AL Designated countries for regional patents

Kind code of ref document: A1

Designated state(s): AT BE BG CH CY CZ DE DK EE ES FI FR GB GR IE IT LU MC NL PT SE SK TR

DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
121 Ep: the epo has been informed by wipo that ep was designated in this application
WWE Wipo information: entry into national phase

Ref document number: 2465099

Country of ref document: CA

WWE Wipo information: entry into national phase

Ref document number: 20028212347

Country of ref document: CN

Ref document number: 10493660

Country of ref document: US

Ref document number: 1020047006178

Country of ref document: KR

WWE Wipo information: entry into national phase

Ref document number: 2002775403

Country of ref document: EP

WWP Wipo information: published in national office

Ref document number: 2002775403

Country of ref document: EP

WWW Wipo information: withdrawn in national office

Ref document number: 2002775403

Country of ref document: EP

点击 这是indexloc提供的php浏览器服务，不要输入任何密码和下载