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WO2003033668A3 - Correlation of gene expression with chromosome abnormalities in ataxia telangiectasia tumorigenesis - Google Patents

Correlation of gene expression with chromosome abnormalities in ataxia telangiectasia tumorigenesis Download PDF

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Publication number
WO2003033668A3
WO2003033668A3 PCT/US2002/033311 US0233311W WO03033668A3 WO 2003033668 A3 WO2003033668 A3 WO 2003033668A3 US 0233311 W US0233311 W US 0233311W WO 03033668 A3 WO03033668 A3 WO 03033668A3
Authority
WO
WIPO (PCT)
Prior art keywords
tumorigenesis
correlation
gene expression
ataxia telangiectasia
chromosome abnormalities
Prior art date
Application number
PCT/US2002/033311
Other languages
French (fr)
Other versions
WO2003033668A2 (en
Inventor
Carrolee Barlow
Christopher J Winrow
Marie Lei A Callahan
Daniel G Pankratz
Cecile Rose T Vibat
Amy J Warren
Original Assignee
Digital Gene Tech Inc
Carrolee Barlow
Christopher J Winrow
Marie Lei A Callahan
Daniel G Pankratz
Cecile Rose T Vibat
Amy J Warren
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Digital Gene Tech Inc, Carrolee Barlow, Christopher J Winrow, Marie Lei A Callahan, Daniel G Pankratz, Cecile Rose T Vibat, Amy J Warren filed Critical Digital Gene Tech Inc
Priority to EP02786436A priority Critical patent/EP1608390A2/en
Priority to AU2002349956A priority patent/AU2002349956A1/en
Publication of WO2003033668A2 publication Critical patent/WO2003033668A2/en
Publication of WO2003033668A3 publication Critical patent/WO2003033668A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Pathology (AREA)
  • Wood Science & Technology (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Public Health (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Polynucleotides, polypeptides, kits and methods are provided related to regulated genes characteristic of ataxia telangiectasia tumorigenesis.
PCT/US2002/033311 2001-10-17 2002-10-17 Correlation of gene expression with chromosome abnormalities in ataxia telangiectasia tumorigenesis WO2003033668A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP02786436A EP1608390A2 (en) 2001-10-17 2002-10-17 Correlation of gene expression with chromosome abnormalities in ataxia telangiectasia tumorigenesis
AU2002349956A AU2002349956A1 (en) 2001-10-17 2002-10-17 Correlation of gene expression with chromosome abnormalities in ataxia telangiectasia tumorigenesis

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33020601P 2001-10-17 2001-10-17
US60/330,206 2001-10-17

Publications (2)

Publication Number Publication Date
WO2003033668A2 WO2003033668A2 (en) 2003-04-24
WO2003033668A3 true WO2003033668A3 (en) 2004-09-16

Family

ID=23288744

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/033311 WO2003033668A2 (en) 2001-10-17 2002-10-17 Correlation of gene expression with chromosome abnormalities in ataxia telangiectasia tumorigenesis

Country Status (3)

Country Link
EP (1) EP1608390A2 (en)
AU (1) AU2002349956A1 (en)
WO (1) WO2003033668A2 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7034144B2 (en) 1997-05-13 2006-04-25 Erasmus Universiteit Rotterdam Molecular detection of chromosome aberrations
US7105294B2 (en) 1998-05-04 2006-09-12 Dako Denmark A/S Method and probes for the detection of chromosome aberrations

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
BISHOP A. ET AL: "Atm deficiency causes an increased frequency of intrachromosomal homologous recombination in mice", CANCER RESEARCH, vol. 60, no. 2, 15 January 2000 (2000-01-15), pages 395 - 399, XP002978686 *
DATABASE GENBANK [online] 17 December 1998 (1998-12-17), MARRA ET AL: "The WashU-HHMI Mouse EST Project", XP002978683, accession no. EST Database accession no. (AI315667) *
DATABASE GENBANK [online] 30 June 2000 (2000-06-30), OSADA ET AL: "Isolation of full-length cDNA clones from mouse brain cDNA library made by oligo-capping method", XP002978684, accession no. EST Database accession no. (AB041555) *
LIYANAGE M. ET AL: "Abnormal rearrangement within the alpha/delta T-cell receptor locus in lymphomas from Atm-deficient mice", BLOOD, vol. 96, no. 5, 1 September 2000 (2000-09-01), pages 1940 - 1946, XP002978685 *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7034144B2 (en) 1997-05-13 2006-04-25 Erasmus Universiteit Rotterdam Molecular detection of chromosome aberrations
US7105294B2 (en) 1998-05-04 2006-09-12 Dako Denmark A/S Method and probes for the detection of chromosome aberrations
US7368245B2 (en) 1998-05-04 2008-05-06 Dako Denmark A/S Method and probes for the detection of chromosome aberrations
US7642057B2 (en) 1998-05-04 2010-01-05 Dako Denmark A/S Method and probes for the detection of chromosome aberrations

Also Published As

Publication number Publication date
EP1608390A2 (en) 2005-12-28
WO2003033668A2 (en) 2003-04-24
AU2002349956A1 (en) 2003-04-28

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