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WO2003029261A3 - Polymeres de glycosaminoglycane et procedes de preparation et d'utilisation de ces derniers - Google Patents

Polymeres de glycosaminoglycane et procedes de preparation et d'utilisation de ces derniers Download PDF

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Publication number
WO2003029261A3
WO2003029261A3 PCT/US2002/022386 US0222386W WO03029261A3 WO 2003029261 A3 WO2003029261 A3 WO 2003029261A3 US 0222386 W US0222386 W US 0222386W WO 03029261 A3 WO03029261 A3 WO 03029261A3
Authority
WO
WIPO (PCT)
Prior art keywords
making
methods
same
glycosaminoglycan polymers
polymer grafting
Prior art date
Application number
PCT/US2002/022386
Other languages
English (en)
Other versions
WO2003029261A9 (fr
WO2003029261A2 (fr
Inventor
Paul L Deangelis
Original Assignee
Paul L Deangelis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/142,143 external-priority patent/US7307159B2/en
Application filed by Paul L Deangelis filed Critical Paul L Deangelis
Priority to AU2002361549A priority Critical patent/AU2002361549A1/en
Priority to EP02797026A priority patent/EP1470235A4/fr
Publication of WO2003029261A2 publication Critical patent/WO2003029261A2/fr
Publication of WO2003029261A9 publication Critical patent/WO2003029261A9/fr
Publication of WO2003029261A3 publication Critical patent/WO2003029261A3/fr

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/06Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/04Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

La présente invention concerne une méthodologie de greffe polymère par une synthase de polysaccharide et, plus particulièrement, la greffe polymère effectuée à l'aide de synthases de hyaluronate ou de chondroïtine ou d'héparine/héparosane issues de Pasteurella multocida, qu'on effectue afin de créer une variété d'oligosaccharides de glycosaminoglycane ayant une structure de sucre naturelle ou chimérique ou bien hybride.
PCT/US2002/022386 2001-07-13 2002-07-12 Polymeres de glycosaminoglycane et procedes de preparation et d'utilisation de ces derniers WO2003029261A2 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU2002361549A AU2002361549A1 (en) 2001-07-13 2002-07-12 Glycosaminoglycan polymers and methods of making and using same
EP02797026A EP1470235A4 (fr) 2001-07-13 2002-07-12 Polymeres de glycosaminoglycane et procedes de preparation et d'utilisation de ces derniers

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US30526301P 2001-07-13 2001-07-13
US60/305,263 2001-07-13
US34549701P 2001-11-09 2001-11-09
US60/345,497 2001-11-09
US35064202P 2002-01-22 2002-01-22
US60/350,642 2002-01-22
US10/142,143 2002-05-08
US10/142,143 US7307159B2 (en) 2001-05-08 2002-05-08 Heparin/heparosan synthase from P. multocida and methods of making and using same

Publications (3)

Publication Number Publication Date
WO2003029261A2 WO2003029261A2 (fr) 2003-04-10
WO2003029261A9 WO2003029261A9 (fr) 2004-06-10
WO2003029261A3 true WO2003029261A3 (fr) 2004-08-12

Family

ID=32398225

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/022386 WO2003029261A2 (fr) 2001-07-13 2002-07-12 Polymeres de glycosaminoglycane et procedes de preparation et d'utilisation de ces derniers

Country Status (3)

Country Link
EP (1) EP1470235A4 (fr)
AU (1) AU2002361549A1 (fr)
WO (1) WO2003029261A2 (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7307159B2 (en) 2001-05-08 2007-12-11 The Board Of Regents Of The University Of Oklahoma Heparin/heparosan synthase from P. multocida and methods of making and using same
US8088604B2 (en) 1998-04-02 2012-01-03 The Board Of Regents Of The University Of Oklahoma Production of defined monodisperse heparosan polymers and unnatural polymers with polysaccharide synthases
US8580290B2 (en) 2001-05-08 2013-11-12 The Board Of Regents Of The University Of Oklahoma Heparosan-based biomaterials and coatings and methods of production and use thereof
US9687559B2 (en) 2008-03-19 2017-06-27 The Board Of Regents Of The University Of Oklahoma Heparosan polymers and methods of making and using same for the enhancement of therapeutics
US9925209B2 (en) 2008-03-19 2018-03-27 The Board Of Regents Of The University Of Oklahoma Heparosan-polypeptide and heparosan-polynucleotide drug conjugates and methods of making and using same
ES2661593T3 (es) 2010-03-01 2018-04-02 Seikagaku Corporation Composiciones y métodos para producción bacteriana de condroitina
EP2831237B1 (fr) 2012-03-30 2017-11-29 The Board of Regents of the University of Oklahoma Polymères d'héparosane de poids moléculaire élevé et procédés de production et d'utilisation de ceux-ci
KR20220110798A (ko) * 2019-12-02 2022-08-09 아반트 미츠 컴퍼니 리미티드 시험관내 세포 배양에 의한 고기 제조 방법

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002529064A (ja) * 1998-11-11 2002-09-10 ザ ボード オブ リージェンツ オブ ザ ユニヴァーシティー オブ オクラホマ 多糖類シンターゼによるポリマーグラフティング
AU2001253805B2 (en) * 2000-04-25 2006-08-03 De Angelis, Paul L Chondroitin synthase gene and methods of making and using same

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DEANGELIS ET AL: "Identification and Molecular Cloning of a Chondroitin Synthase from Pasteurella Multocida Type F", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 275, no. 31, 4 August 2000 (2000-08-04), pages 24124 - 24129, XP002163608 *
See also references of EP1470235A4 *

Also Published As

Publication number Publication date
WO2003029261A9 (fr) 2004-06-10
WO2003029261A2 (fr) 2003-04-10
AU2002361549A1 (en) 2003-04-14
EP1470235A4 (fr) 2008-05-21
EP1470235A2 (fr) 2004-10-27

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