WO2003016544A1 - Procede d'elaboration d'acide 1,4-dihydroxy-2-naphtoique - Google Patents
Procede d'elaboration d'acide 1,4-dihydroxy-2-naphtoique Download PDFInfo
- Publication number
- WO2003016544A1 WO2003016544A1 PCT/JP2002/008010 JP0208010W WO03016544A1 WO 2003016544 A1 WO2003016544 A1 WO 2003016544A1 JP 0208010 W JP0208010 W JP 0208010W WO 03016544 A1 WO03016544 A1 WO 03016544A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- dihydroxy
- naphthoic acid
- producing
- composition
- unpleasantness
- Prior art date
Links
- VOJUXHHACRXLTD-UHFFFAOYSA-N 1,4-dihydroxy-2-naphthoic acid Chemical compound C1=CC=CC2=C(O)C(C(=O)O)=CC(O)=C21 VOJUXHHACRXLTD-UHFFFAOYSA-N 0.000 title abstract 6
- 239000000203 mixture Substances 0.000 abstract 2
- 241000894006 Bacteria Species 0.000 abstract 1
- 208000029725 Metabolic bone disease Diseases 0.000 abstract 1
- 241000186429 Propionibacterium Species 0.000 abstract 1
- 230000003187 abdominal effect Effects 0.000 abstract 1
- 239000008267 milk Substances 0.000 abstract 1
- 210000004080 milk Anatomy 0.000 abstract 1
- 235000013336 milk Nutrition 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/42—Hydroxy-carboxylic acids
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Nutrition Science (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Polymers & Plastics (AREA)
- Mycology (AREA)
- Food Science & Technology (AREA)
- Epidemiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Priority Applications (10)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2002323899A AU2002323899B2 (en) | 2001-08-10 | 2002-08-06 | Process for producing 1,4-dihydroxy -2-naphthoic acid |
NZ531192A NZ531192A (en) | 2001-08-10 | 2002-08-06 | Process for producing 1,4-dihydroxy-2-naphthoic acid and compositions made therefrom for regulating intestinal function |
KR1020047001743A KR100899615B1 (ko) | 2001-08-10 | 2002-08-06 | 1,4-디히드록시-2-나프토산의 제조방법 |
JP2003521851A JP4070721B2 (ja) | 2001-08-10 | 2002-08-06 | 1,4−ジヒドロキシ−2−ナフトエ酸の製造法 |
CA2457055A CA2457055C (en) | 2001-08-10 | 2002-08-06 | Process for producing 1,4-dihydroxy-2-naphthoic acid |
US10/486,421 US7374915B2 (en) | 2001-08-10 | 2002-08-06 | Process for producing 1,4-dihydroxy-2-naphthoic acid |
EP02755845A EP1416052B8 (en) | 2001-08-10 | 2002-08-06 | Process for producing 1,4-dihydroxy-2-naphthoic acid |
US12/100,075 US7629155B2 (en) | 2001-08-10 | 2008-04-09 | Process for producing 1,4-dihydroxy-2-naphthoic acid |
US12/543,814 US7834061B2 (en) | 2001-08-10 | 2009-08-19 | Process for producing 1,4-dihydroxy-2-naphthoic acid |
US12/877,471 US8110607B2 (en) | 2001-08-10 | 2010-09-08 | Process for producing 1,4-dihydroxy-2-naphthoic acid |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2001-244475 | 2001-08-10 | ||
JP2001244475 | 2001-08-10 |
Related Child Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US10486421 A-371-Of-International | 2002-08-06 | ||
US12/100,075 Division US7629155B2 (en) | 2001-08-10 | 2008-04-09 | Process for producing 1,4-dihydroxy-2-naphthoic acid |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2003016544A1 true WO2003016544A1 (fr) | 2003-02-27 |
Family
ID=19074394
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/JP2002/008010 WO2003016544A1 (fr) | 2001-08-10 | 2002-08-06 | Procede d'elaboration d'acide 1,4-dihydroxy-2-naphtoique |
Country Status (9)
Country | Link |
---|---|
US (4) | US7374915B2 (ja) |
EP (1) | EP1416052B8 (ja) |
JP (1) | JP4070721B2 (ja) |
KR (1) | KR100899615B1 (ja) |
CN (2) | CN1820741A (ja) |
AU (1) | AU2002323899B2 (ja) |
CA (1) | CA2457055C (ja) |
NZ (1) | NZ531192A (ja) |
WO (1) | WO2003016544A1 (ja) |
Cited By (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2004085364A1 (ja) * | 2003-03-26 | 2004-10-07 | Meiji Dairies Corporation | 1,4−ジヒドロキシ−2−ナフトエ酸の安定化方法 |
WO2005033323A1 (ja) * | 2003-10-01 | 2005-04-14 | Meiji Dairies Corporation | 1,4−ジヒドロキシ−2−ナフトエ酸の製造法 |
WO2005072718A1 (ja) * | 2004-01-28 | 2005-08-11 | Kurume University | 乳清発酵物を含有する医薬組成物 |
JP2005225794A (ja) * | 2004-02-12 | 2005-08-25 | Meiji Milk Prod Co Ltd | 1,4−ジヒドロキシ−2−ナフトエ酸の安定化剤 |
WO2005099725A1 (ja) * | 2004-04-13 | 2005-10-27 | Meiji Dairies Corporation | 炎症性腸疾患予防および/または治療剤 |
WO2006098447A1 (ja) * | 2005-03-18 | 2006-09-21 | Meiji Feed. Co., Ltd. | ビフィズス菌増殖促進成分を含有する飼料組成物及びその使用方法 |
WO2008088008A1 (ja) | 2007-01-17 | 2008-07-24 | Meiji Dairies Corporation | 消化管機能異常症予防及び/又は治療剤 |
WO2009107380A1 (ja) | 2008-02-29 | 2009-09-03 | 明治乳業株式会社 | 抗アレルギー剤 |
WO2014163031A1 (ja) * | 2013-04-01 | 2014-10-09 | 株式会社明治 | 即効性の整腸剤 |
JP2016020339A (ja) * | 2014-06-16 | 2016-02-04 | 学校法人産業医科大学 | 1,4−ジヒドロキシ−2−ナフトエ酸誘導体 |
JP2016164144A (ja) * | 2010-05-21 | 2016-09-08 | 株式会社明治 | 皮膚状態の改善用組成物 |
KR20170022343A (ko) | 2015-08-20 | 2017-03-02 | 김태웅 | 유산균 발효액, 플로랄 워터 및 생약 추출물을 기반으로 하는 피부 알레르기의 예방, 개선제 |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2002323899B2 (en) | 2001-08-10 | 2007-06-28 | Meiji Dairies Corporation | Process for producing 1,4-dihydroxy -2-naphthoic acid |
US7241809B2 (en) * | 2003-12-22 | 2007-07-10 | Meiji Dairies Corporation | Method for treating inflammatory bowel diseases |
US8093301B2 (en) | 2005-08-26 | 2012-01-10 | Meiji Co., Ltd. | Anti-allergic agent |
KR20100087078A (ko) * | 2007-11-27 | 2010-08-03 | 메이지뉴교오가부시기가이샤 | 유산균의 생잔성 향상제 및 생잔성 향상 방법, 및 식품 조성물 |
US8715644B2 (en) * | 2008-05-26 | 2014-05-06 | Compagnie Gervais Danone | Method for decreasing borborygmi by administering a bifidobacterium bacteria |
FR2960001A1 (fr) | 2010-05-12 | 2011-11-18 | Univ Rennes | Vecteur recombinant pour la production et la secretion de sequences d'acides amines d'interet par les bacteries propioniques et ses applications |
KR101342791B1 (ko) | 2012-08-16 | 2013-12-19 | 주식회사 제이케이뉴트라 | 1,4-디히드록시-2-나프토산 생산능을 가지는 락토바실러스 카제이 lp1 균주 및 이의 이용 |
US11179427B2 (en) | 2013-01-21 | 2021-11-23 | Eth Zurich | Baby food composition comprising viable propionic acid-producing bacteria |
EP2829274A1 (en) | 2013-07-25 | 2015-01-28 | Institut National De La Recherche Agronomique | Vectors for producing and secreting substance of interest by bacteria and applications thereof |
WO2016183535A1 (en) | 2015-05-14 | 2016-11-17 | University Of Puerto Rico | Methods for restoring microbiota of newborns |
WO2017117142A1 (en) | 2015-12-28 | 2017-07-06 | New York University | Device and method of restoring microbiota of newborns |
KR102127108B1 (ko) * | 2018-06-26 | 2020-06-26 | 고려대학교산학협력단 | 프로피오니바크테리움 후레우덴레이키, 이의 배양액 또는 이의 사균체를 유효성분으로 함유하는 골질환의 예방 또는 치료용 조성물 |
Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0898677A (ja) * | 1994-04-26 | 1996-04-16 | Meiji Milk Prod Co Ltd | ビフィズス菌増殖促進組成物 |
JPH0975095A (ja) * | 1995-09-14 | 1997-03-25 | Unitika Ltd | 2,4−ジヒドロキシ−3−ナフトエ酸の製造方法 |
JPH1014589A (ja) * | 1996-07-08 | 1998-01-20 | Unitika Ltd | キャンディダ・リポリティカhna−110株及び2,6−ジヒドロキシ−3−ナフトエ酸の製造方法 |
JPH11228424A (ja) * | 1998-02-06 | 1999-08-24 | Kyodo Milk Ind Co Ltd | ビフィズス菌活性化物質とビフィズス菌活性増殖剤とそれを含有する食品 |
JP2000086525A (ja) * | 1998-09-16 | 2000-03-28 | Morishita Jintan Kk | カプセル配合打錠剤 |
JP2000256201A (ja) * | 1999-03-02 | 2000-09-19 | Meiji Milk Prod Co Ltd | ビフィズス菌によるオリゴ糖利用能改善剤 |
WO2001028547A1 (fr) * | 1999-10-19 | 2001-04-26 | Meiji Milk Products Co., Ltd | Produits alimentaires utiles dans la prevention et l'amelioration de maladies du metabolisme osseux et medicaments preventifs/therapeutiques pour des maladies du metabolisme osseux comprenant ces produits alimentaires |
JP2001169749A (ja) * | 1999-12-21 | 2001-06-26 | Nitto Yakuhin Kogyo Kk | 生菌組成物 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5935910B2 (ja) | 1981-02-02 | 1984-08-31 | 株式会社日本触媒 | 1,4−ジヒドロオキシ−2−ナフトエ酸の製造方法 |
JPS59186942A (ja) | 1983-04-07 | 1984-10-23 | Kawasaki Kasei Chem Ltd | 粗製1,4−ジヒドロキシ−2−ナフトエ酸又はその塩の精製法 |
JPS60104037A (ja) * | 1983-11-10 | 1985-06-08 | Kawasaki Kasei Chem Ltd | 1,4−ジヒドロキシ−2−ナフトエ酸の製造方法 |
AU2002323899B2 (en) | 2001-08-10 | 2007-06-28 | Meiji Dairies Corporation | Process for producing 1,4-dihydroxy -2-naphthoic acid |
-
2002
- 2002-08-06 AU AU2002323899A patent/AU2002323899B2/en not_active Expired
- 2002-08-06 JP JP2003521851A patent/JP4070721B2/ja not_active Expired - Fee Related
- 2002-08-06 EP EP02755845A patent/EP1416052B8/en not_active Expired - Lifetime
- 2002-08-06 NZ NZ531192A patent/NZ531192A/en not_active IP Right Cessation
- 2002-08-06 CN CNA200510136146XA patent/CN1820741A/zh active Pending
- 2002-08-06 WO PCT/JP2002/008010 patent/WO2003016544A1/ja active IP Right Grant
- 2002-08-06 KR KR1020047001743A patent/KR100899615B1/ko not_active Expired - Lifetime
- 2002-08-06 US US10/486,421 patent/US7374915B2/en not_active Expired - Lifetime
- 2002-08-06 CA CA2457055A patent/CA2457055C/en not_active Expired - Lifetime
- 2002-08-06 CN CNB028155807A patent/CN1312285C/zh not_active Expired - Lifetime
-
2008
- 2008-04-09 US US12/100,075 patent/US7629155B2/en not_active Expired - Lifetime
-
2009
- 2009-08-19 US US12/543,814 patent/US7834061B2/en not_active Expired - Lifetime
-
2010
- 2010-09-08 US US12/877,471 patent/US8110607B2/en not_active Expired - Fee Related
Patent Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0898677A (ja) * | 1994-04-26 | 1996-04-16 | Meiji Milk Prod Co Ltd | ビフィズス菌増殖促進組成物 |
JPH0975095A (ja) * | 1995-09-14 | 1997-03-25 | Unitika Ltd | 2,4−ジヒドロキシ−3−ナフトエ酸の製造方法 |
JPH1014589A (ja) * | 1996-07-08 | 1998-01-20 | Unitika Ltd | キャンディダ・リポリティカhna−110株及び2,6−ジヒドロキシ−3−ナフトエ酸の製造方法 |
JPH11228424A (ja) * | 1998-02-06 | 1999-08-24 | Kyodo Milk Ind Co Ltd | ビフィズス菌活性化物質とビフィズス菌活性増殖剤とそれを含有する食品 |
JP2000086525A (ja) * | 1998-09-16 | 2000-03-28 | Morishita Jintan Kk | カプセル配合打錠剤 |
JP2000256201A (ja) * | 1999-03-02 | 2000-09-19 | Meiji Milk Prod Co Ltd | ビフィズス菌によるオリゴ糖利用能改善剤 |
WO2001028547A1 (fr) * | 1999-10-19 | 2001-04-26 | Meiji Milk Products Co., Ltd | Produits alimentaires utiles dans la prevention et l'amelioration de maladies du metabolisme osseux et medicaments preventifs/therapeutiques pour des maladies du metabolisme osseux comprenant ces produits alimentaires |
JP2001169749A (ja) * | 1999-12-21 | 2001-06-26 | Nitto Yakuhin Kogyo Kk | 生菌組成物 |
Non-Patent Citations (2)
Title |
---|
KANEKO T. AND NODA K.: "Bifidogenic growth stimulator produces by propionic acid bacteria", JAPANESE JOURNAL OF DAIRY AND FOOD SCIENCE, vol. 45, no. 4, 1995, pages 83 - 91, XP002957396 * |
MEGANATHAN R. ET AL.: "Menaquinone (vitamin K2) bio-synthesis: conversion of omicron-succinylbenzoic acid to 1,4-dihydroxy-2-naphthoic acid by mycobacterium phylei enzymes", J. BACTERIOL., vol. 140, no. 1, October 1979 (1979-10-01), pages 92 - 98, XP002957395 * |
Cited By (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2010233577A (ja) * | 2003-03-26 | 2010-10-21 | Meiji Milk Prod Co Ltd | 1,4−ジヒドロキシ−2−ナフトエ酸(dhna)を含有する飲食品の製造方法 |
CN1764627B (zh) * | 2003-03-26 | 2016-05-25 | 株式会社明治 | 稳定1,4-二羟基-2-萘甲酸的方法 |
WO2004085364A1 (ja) * | 2003-03-26 | 2004-10-07 | Meiji Dairies Corporation | 1,4−ジヒドロキシ−2−ナフトエ酸の安定化方法 |
US8277860B2 (en) | 2003-03-26 | 2012-10-02 | Meiji Co., Ltd. | Method of stabilizing 1,4-dihydroxy-2-naphthoic acid |
KR101003344B1 (ko) * | 2003-03-26 | 2010-12-23 | 메이지 데어리스 코포레이션 | 1,4-디히드록시-2-나프토산의 안정화 방법 |
JPWO2004085364A1 (ja) * | 2003-03-26 | 2006-06-29 | 明治乳業株式会社 | 1,4−ジヒドロキシ−2−ナフトエ酸の安定化方法 |
JP4579158B2 (ja) * | 2003-03-26 | 2010-11-10 | 明治乳業株式会社 | 1,4−ジヒドロキシ−2−ナフトエ酸の安定化方法 |
US8758842B2 (en) | 2003-10-01 | 2014-06-24 | Meiji Co., Ltd. | Process for producing 1,4-dihydroxy-2-naphthoic acid |
EP2463376A3 (en) * | 2003-10-01 | 2013-01-30 | Meiji Co, Ltd. | Food and beverages for treating metabolic osteopathy |
EP2463375A2 (en) | 2003-10-01 | 2012-06-13 | Meiji Co., Ltd. | Food and beverages for treating abdominal discomfort |
WO2005033323A1 (ja) * | 2003-10-01 | 2005-04-14 | Meiji Dairies Corporation | 1,4−ジヒドロキシ−2−ナフトエ酸の製造法 |
CN100422337C (zh) * | 2003-10-01 | 2008-10-01 | 明治乳业株式会社 | 1,4-二羟基-2-萘甲酸的制造方法 |
US7507563B2 (en) | 2003-10-01 | 2009-03-24 | Meiji Dairies Corporation | Process for producing 1, 4-dihydroxy-2-naphthoic acid |
EP2463376A2 (en) | 2003-10-01 | 2012-06-13 | Meiji Co, Ltd. | Food and beverages for treating metabolic osteopathy |
KR101116244B1 (ko) * | 2003-10-01 | 2012-03-09 | 가부시키가이샤 메이지 | 1,4-디히드록시-2-나프토산의 제조법 |
JPWO2005033323A1 (ja) * | 2003-10-01 | 2007-11-15 | 明治乳業株式会社 | 1,4−ジヒドロキシ−2−ナフトエ酸の製造法 |
EP2463375A3 (en) * | 2003-10-01 | 2013-01-30 | Meiji Co., Ltd. | Food and beverages for treating abdominal discomfort |
JP4613132B2 (ja) * | 2003-10-01 | 2011-01-12 | 明治乳業株式会社 | 1,4−ジヒドロキシ−2−ナフトエ酸の製造法 |
WO2005072718A1 (ja) * | 2004-01-28 | 2005-08-11 | Kurume University | 乳清発酵物を含有する医薬組成物 |
JP4507065B2 (ja) * | 2004-02-12 | 2010-07-21 | 明治乳業株式会社 | 1,4−ジヒドロキシ−2−ナフトエ酸の安定化剤 |
JP2005225794A (ja) * | 2004-02-12 | 2005-08-25 | Meiji Milk Prod Co Ltd | 1,4−ジヒドロキシ−2−ナフトエ酸の安定化剤 |
WO2005099725A1 (ja) * | 2004-04-13 | 2005-10-27 | Meiji Dairies Corporation | 炎症性腸疾患予防および/または治療剤 |
US8025911B2 (en) | 2004-04-13 | 2011-09-27 | Meiji Dairies Corporation | Preventive and/or remedy for inflammatory bowel diseases |
JPWO2005099725A1 (ja) * | 2004-04-13 | 2008-03-06 | 明治乳業株式会社 | 炎症性腸疾患予防および/または治療剤 |
US8241684B2 (en) | 2004-04-13 | 2012-08-14 | Meiji Co., Ltd. | Preventive and/or therapeutic agent for inflammatory bowel diseases |
JP2006254841A (ja) * | 2005-03-18 | 2006-09-28 | Meiji Shiryo Kk | ビフィズス菌増殖促進成分を含有する飼料組成物とその使用方法 |
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US9675647B2 (en) | 2007-01-17 | 2017-06-13 | Meiji Co., Ltd. | Prophylactic and/or therapeutic agent for functional gastrointestinal disorders |
WO2009107380A1 (ja) | 2008-02-29 | 2009-09-03 | 明治乳業株式会社 | 抗アレルギー剤 |
JP2016164144A (ja) * | 2010-05-21 | 2016-09-08 | 株式会社明治 | 皮膚状態の改善用組成物 |
WO2014163031A1 (ja) * | 2013-04-01 | 2014-10-09 | 株式会社明治 | 即効性の整腸剤 |
JPWO2014163031A1 (ja) * | 2013-04-01 | 2017-02-16 | 株式会社明治 | 即効性の整腸剤 |
JP2016020339A (ja) * | 2014-06-16 | 2016-02-04 | 学校法人産業医科大学 | 1,4−ジヒドロキシ−2−ナフトエ酸誘導体 |
JP2020010703A (ja) * | 2014-06-16 | 2020-01-23 | 学校法人産業医科大学 | 1,4−ジヒドロキシ−2−ナフトエ酸誘導体 |
KR20170022343A (ko) | 2015-08-20 | 2017-03-02 | 김태웅 | 유산균 발효액, 플로랄 워터 및 생약 추출물을 기반으로 하는 피부 알레르기의 예방, 개선제 |
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Publication number | Publication date |
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US7374915B2 (en) | 2008-05-20 |
KR100899615B1 (ko) | 2009-05-27 |
JP4070721B2 (ja) | 2008-04-02 |
NZ531192A (en) | 2005-07-29 |
CA2457055A1 (en) | 2003-02-27 |
EP1416052B1 (en) | 2012-09-12 |
KR20040032886A (ko) | 2004-04-17 |
AU2002323899B9 (en) | 2003-03-03 |
EP1416052B8 (en) | 2013-01-09 |
JPWO2003016544A1 (ja) | 2004-12-02 |
US20110009491A1 (en) | 2011-01-13 |
US7834061B2 (en) | 2010-11-16 |
US7629155B2 (en) | 2009-12-08 |
CN1820741A (zh) | 2006-08-23 |
US20040241815A1 (en) | 2004-12-02 |
CA2457055C (en) | 2013-10-08 |
CN1312285C (zh) | 2007-04-25 |
EP1416052A4 (en) | 2005-10-12 |
EP1416052A1 (en) | 2004-05-06 |
US8110607B2 (en) | 2012-02-07 |
US20090312425A1 (en) | 2009-12-17 |
CN1539019A (zh) | 2004-10-20 |
US20080194688A1 (en) | 2008-08-14 |
AU2002323899B2 (en) | 2007-06-28 |
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