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WO2003014152A3 - Proteines de liaison - Google Patents

Proteines de liaison Download PDF

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Publication number
WO2003014152A3
WO2003014152A3 PCT/IB2002/003645 IB0203645W WO03014152A3 WO 2003014152 A3 WO2003014152 A3 WO 2003014152A3 IB 0203645 W IB0203645 W IB 0203645W WO 03014152 A3 WO03014152 A3 WO 03014152A3
Authority
WO
WIPO (PCT)
Prior art keywords
phosphatidylinositol
phosphate
binding proteins
proteins
vivo
Prior art date
Application number
PCT/IB2002/003645
Other languages
English (en)
Other versions
WO2003014152A2 (fr
Inventor
Stephen Cohen
Aurelio Teleman
Original Assignee
European Molecular Biology Lab Embl
Stephen Cohen
Aurelio Teleman
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by European Molecular Biology Lab Embl, Stephen Cohen, Aurelio Teleman filed Critical European Molecular Biology Lab Embl
Priority to AU2002328115A priority Critical patent/AU2002328115A1/en
Publication of WO2003014152A2 publication Critical patent/WO2003014152A2/fr
Publication of WO2003014152A3 publication Critical patent/WO2003014152A3/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)

Abstract

L'invention concerne des protéines qui se lient au phosphatidylinositol 5-phosphate (PI(5)P). L'invention concerne également l'utilisation de ces protéines pour mesurer et visualiser le PI(5)P in vivo et in vitro et comme outils pour étudier le rôle du PI(5)P in vivo.
PCT/IB2002/003645 2001-08-09 2002-08-08 Proteines de liaison WO2003014152A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002328115A AU2002328115A1 (en) 2001-08-09 2002-08-08 Phosphatidylinositol 5-phosphate-binding proteins

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0119446.3 2001-08-09
GBGB0119446.3A GB0119446D0 (en) 2001-08-09 2001-08-09 Binding proteins

Publications (2)

Publication Number Publication Date
WO2003014152A2 WO2003014152A2 (fr) 2003-02-20
WO2003014152A3 true WO2003014152A3 (fr) 2003-12-04

Family

ID=9920104

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2002/003645 WO2003014152A2 (fr) 2001-08-09 2002-08-08 Proteines de liaison

Country Status (3)

Country Link
AU (1) AU2002328115A1 (fr)
GB (1) GB0119446D0 (fr)
WO (1) WO2003014152A2 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4612360B2 (ja) * 2004-08-24 2011-01-12 独立行政法人科学技術振興機構 イノシトールリン脂質可視化プローブ遺伝子導入モデル動物
EP1754487A1 (fr) * 2005-07-27 2007-02-21 The European Molecular Biology Laboratory Modulateurs de la protéine Melted et leur utilisation

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
ADAMS M ET AL: "Melt protein", SWALL, XP002235337 *
MORRIS J B ET AL: "Thrombin stimulation of platelets causes an increase in phosphatidylinositol 5-phosphate revealed by mass assay", FEBS LETTERS, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL, vol. 475, no. 1, 9 June 2000 (2000-06-09), pages 57 - 60, XP004337233, ISSN: 0014-5793 *
SHISHEVA ASSIA: "PIKfyve: The road to PtdIns 5-P and PtdIns 3,5-P2.", CELL BIOLOGY INTERNATIONAL, vol. 25, no. 12, 2001, 2001, pages 1201 - 1206, XP002245798, ISSN: 1065-6995 *

Also Published As

Publication number Publication date
WO2003014152A2 (fr) 2003-02-20
AU2002328115A1 (en) 2003-02-24
GB0119446D0 (en) 2001-10-03

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