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WO2003012079A1 - Procede permettant la culture a densite elevee de cellules, et dispositif de culture faisant intervenir une feuille d'apatite, et module de culture cellulaire - Google Patents

Procede permettant la culture a densite elevee de cellules, et dispositif de culture faisant intervenir une feuille d'apatite, et module de culture cellulaire Download PDF

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Publication number
WO2003012079A1
WO2003012079A1 PCT/JP2002/007766 JP0207766W WO03012079A1 WO 2003012079 A1 WO2003012079 A1 WO 2003012079A1 JP 0207766 W JP0207766 W JP 0207766W WO 03012079 A1 WO03012079 A1 WO 03012079A1
Authority
WO
WIPO (PCT)
Prior art keywords
cell culture
module
sheet
apatite sheet
apatite
Prior art date
Application number
PCT/JP2002/007766
Other languages
English (en)
Japanese (ja)
Inventor
Sanetaka Shirahata
Hironobu Kawakatsu
Hiroshi Kanegae
Original Assignee
Astec Co., Ltd.
Fukuoka Prefecture
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astec Co., Ltd., Fukuoka Prefecture filed Critical Astec Co., Ltd.
Publication of WO2003012079A1 publication Critical patent/WO2003012079A1/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/14—Scaffolds; Matrices
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/10—Mineral substrates
    • C12N2533/18—Calcium salts, e.g. apatite, Mineral components from bones, teeth, shells

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

La présente invention a pour objet un procédé de culture à densité élevée de cellules faisant intervenir une feuille d'apatite et un dispositif de culture destiné à être utilisé dans le cadre dudit procédé. Un module de culture cellulaire utilisant une feuille d'apatite en tant que lit de culture cellulaire a été mis au point pour la première fois. Dans ce module, une substance est introduite à travers le lit de culture cellulaire à feuille d'apatite intégré dans le module, et les cellules prolifèrent ainsi dans la feuille. A savoir, la structure à cellules ouvertes caractéristique des fibres de la feuille d'apatite est utilisée dans ce procédé.
PCT/JP2002/007766 2001-07-31 2002-07-30 Procede permettant la culture a densite elevee de cellules, et dispositif de culture faisant intervenir une feuille d'apatite, et module de culture cellulaire WO2003012079A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2001232821A JP2003047461A (ja) 2001-07-31 2001-07-31 アパタイトシ−トを用いた細胞の高密度細胞培養法及び培養装置、細胞培養モジュール
JP2001-232821 2001-07-31

Publications (1)

Publication Number Publication Date
WO2003012079A1 true WO2003012079A1 (fr) 2003-02-13

Family

ID=19064676

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2002/007766 WO2003012079A1 (fr) 2001-07-31 2002-07-30 Procede permettant la culture a densite elevee de cellules, et dispositif de culture faisant intervenir une feuille d'apatite, et module de culture cellulaire

Country Status (2)

Country Link
JP (1) JP2003047461A (fr)
WO (1) WO2003012079A1 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2416777A (en) * 2004-07-28 2006-02-08 Pentax Corp Cell culture apparatus
US7563608B2 (en) 2002-08-12 2009-07-21 Hoya Corporation Method for manufacturing a sintered compact for use as a cell culture base

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4540905B2 (ja) 2001-11-13 2010-09-08 Ｈｏｙａ株式会社 焼結体の製造方法
JP4756816B2 (ja) * 2003-03-10 2011-08-24 株式会社アドバンス 骨再生補綴物の製造方法
JP4820979B2 (ja) * 2004-10-12 2011-11-24 国立大学法人広島大学 細胞培養装置
JP4671365B2 (ja) * 2005-02-15 2011-04-13 学校法人北里研究所 高密度培養組織の製造方法及び高密度培養組織
JP2008199897A (ja) * 2005-05-16 2008-09-04 Applied Cell Biotechnologies Inc 細胞培養用基材及び細胞培養方法
JP4045289B2 (ja) * 2006-04-12 2008-02-13 株式会社エーシーバイオテクノロジーズ コラーゲン類生産方法及びコラーゲン類
JP2008194029A (ja) * 2007-01-19 2008-08-28 Tosoh Corp 細胞融合装置及びそれを用いた細胞融合方法
ES2647294T3 (es) * 2007-12-27 2017-12-20 Baxalta GmbH Procedimientos de cultivo celular
CN111139216B (zh) * 2018-11-01 2024-09-03 上海药明生物技术有限公司 高通量、自动化的细胞连续培养方法及其应用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6128385A (ja) * 1984-07-17 1986-02-08 Hitachi Ltd 動物細胞の培養方法および装置

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6128385A (ja) * 1984-07-17 1986-02-08 Hitachi Ltd 動物細胞の培養方法および装置

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
HIRONOBU KAWAKATSU ET AL.: "Saibo baiyodoko apataito sheet no tokusei oyobi sheet o shiyoshita CHO-K1 saibo no seichi baiyo", FIBER, vol. 56, no. 4, 2000, pages 205 - 209, XP002957378 *
HIRONOBU KAWAKATSU: "Saibo baiyodoko to shite no apatite sheet", THE SOCIETY OF FIBER SCIENCE AND TECHNOLOGY, JAPAN, SYMPOSIUM YOKOSHU, vol. 1999, 1999, pages S120, XP002957379 *
KAWAKATSU H. ET AL.: "Hydroxyapatite-pulp composite fiber sheet bed: A new material for the immobilization of CHO-K1 cells", CYTOTECHNOLOGY, vol. 35, no. 1, January 2001 (2001-01-01), pages 65 - 72, XP002957377 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7563608B2 (en) 2002-08-12 2009-07-21 Hoya Corporation Method for manufacturing a sintered compact for use as a cell culture base
GB2416777A (en) * 2004-07-28 2006-02-08 Pentax Corp Cell culture apparatus

Also Published As

Publication number Publication date
JP2003047461A (ja) 2003-02-18

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