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WO2003011859A3 - Derives oxazolidinones utilises en tant qu'agents antibacteriens - Google Patents

Derives oxazolidinones utilises en tant qu'agents antibacteriens Download PDF

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Publication number
WO2003011859A3
WO2003011859A3 PCT/GB2002/003404 GB0203404W WO03011859A3 WO 2003011859 A3 WO2003011859 A3 WO 2003011859A3 GB 0203404 W GB0203404 W GB 0203404W WO 03011859 A3 WO03011859 A3 WO 03011859A3
Authority
WO
WIPO (PCT)
Prior art keywords
alkyl
antibacterial agents
substituted
oxazolidinone derivatives
group
Prior art date
Application number
PCT/GB2002/003404
Other languages
English (en)
Other versions
WO2003011859A2 (fr
Inventor
Yusuf Khwaja Hamied
Vithal Madhvarao Kulkarni
Original Assignee
Cipla Ltd
Yusuf Khwaja Hamied
Vithal Madhvarao Kulkarni
Wain Christopher Paul
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cipla Ltd, Yusuf Khwaja Hamied, Vithal Madhvarao Kulkarni, Wain Christopher Paul filed Critical Cipla Ltd
Publication of WO2003011859A2 publication Critical patent/WO2003011859A2/fr
Publication of WO2003011859A3 publication Critical patent/WO2003011859A3/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'invention concerne des composés d'oxazolidine représentés par la formule générale suivante, dans laquelle R1 comprend au moins un groupe phényle substitué ou non et au moins un groupe hétérocyclique insaturé substitué ou non, possédant au moins deux hétéroatomes ; et R2 représente un groupe imide, alkylidène, alkyle, halogène, alcanoyloxy, phosphate, arylsulphonate substitué ou ammonium, un hétérocycle saturé ou insaturé, H, OR3, N3 ou NHR4, R3=H, alkyle C¿1?-C4, SO2(C1-C4)alkyle ; R?4¿=H, alkyle C¿1?-C4, C(=O)(C1-C4)alkyle.
PCT/GB2002/003404 2001-07-27 2002-07-25 Derives oxazolidinones utilises en tant qu'agents antibacteriens WO2003011859A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0118407.6 2001-07-27
GBGB0118407.6A GB0118407D0 (en) 2001-07-27 2001-07-27 Oxazolidinone derivatives as antibacterial agents

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US10/719,232 Continuation US6908013B2 (en) 2001-05-25 2003-11-20 Tamper-evident device

Publications (2)

Publication Number Publication Date
WO2003011859A2 WO2003011859A2 (fr) 2003-02-13
WO2003011859A3 true WO2003011859A3 (fr) 2003-04-03

Family

ID=9919346

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2002/003404 WO2003011859A2 (fr) 2001-07-27 2002-07-25 Derives oxazolidinones utilises en tant qu'agents antibacteriens

Country Status (2)

Country Link
GB (1) GB0118407D0 (fr)
WO (1) WO2003011859A2 (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
YU52403A (sh) 2000-12-26 2006-03-03 Dr.Reddy's Research Foundation Heterociklična jedinjenja koja imaju antibakterijsko dejstvo, postupak za njihovo dobijanje i farmaceutske smeše koje ih sadrže
US7160912B2 (en) 2000-12-26 2007-01-09 Dr.Reddy's Laboratories Ltd. Heterocyclic compounds having antibacterial activity: process for their preparation and pharmaceutical compositions containing them
US7396847B2 (en) 2001-09-11 2008-07-08 Astrazeneca Ab Oxazolidinone and/or isoxazoline as antibacterial agents
EP2181993A1 (fr) 2006-03-31 2010-05-05 Research Foundation Itsuu Laboratory Dérivés d'oxazolidinone antimicrobiens
US7538107B2 (en) 2006-08-15 2009-05-26 Wyeth Oxazinan-2-one derivatives useful as PR modulators
TW200815428A (en) 2006-08-15 2008-04-01 Wyeth Corp Oxazolidone derivatives as PR modulators
WO2008021338A2 (fr) 2006-08-15 2008-02-21 Wyeth Dérivés d'oxazolidone tricycliques utiles en tant que modulateurs du récepteur de la progestérone
US7649007B2 (en) 2006-08-15 2010-01-19 Wyeth Llc Oxazolidine derivatives as PR modulators
US7652018B2 (en) 2006-08-15 2010-01-26 Wyeth Llc Imidazolidin-2-one derivatives useful as PR modulators
EP2669283A1 (fr) 2007-10-02 2013-12-04 Shionogi&Co., Ltd. Dérivé dýoxazolidinone doté dýune bague hétéro composée de 7 éléments
CN116423599B (zh) * 2023-05-29 2024-06-25 德华兔宝宝装饰新材股份有限公司 抗菌阻燃木单板及其制备方法

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0359418A1 (fr) * 1988-09-15 1990-03-21 The Upjohn Company 5-Indolinyl-5-bêta amidométhyloxazolidines-2-one, 3-(phényl condensé)-5 bêta amidométhyloxazolidines-2-ones et 3-phényl-azoté-5 bêta amidométhyloxazolidine 2-one
EP0693491A1 (fr) * 1994-07-20 1996-01-24 Bayer Ag Oxazolidinones substituées par un groupe hétéroaryle à 5 chaínons comme médicament anti-bactérien
WO1997021708A1 (fr) * 1995-12-13 1997-06-19 Pharmacia & Upjohn Company Derives de 4-pyrimidinyl- ou 4-pyrazinyl-piperazinyl-phenyl-oxazolidinone, leur preparation et leur emploi comme agents antibacteriens
WO1999002525A1 (fr) * 1997-07-11 1999-01-21 Pharmacia & Upjohn Company Agents antibacteriens de type phenyloxazolidinones de thiadiazolyle et d'oxadiazolyle

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0359418A1 (fr) * 1988-09-15 1990-03-21 The Upjohn Company 5-Indolinyl-5-bêta amidométhyloxazolidines-2-one, 3-(phényl condensé)-5 bêta amidométhyloxazolidines-2-ones et 3-phényl-azoté-5 bêta amidométhyloxazolidine 2-one
EP0693491A1 (fr) * 1994-07-20 1996-01-24 Bayer Ag Oxazolidinones substituées par un groupe hétéroaryle à 5 chaínons comme médicament anti-bactérien
WO1997021708A1 (fr) * 1995-12-13 1997-06-19 Pharmacia & Upjohn Company Derives de 4-pyrimidinyl- ou 4-pyrazinyl-piperazinyl-phenyl-oxazolidinone, leur preparation et leur emploi comme agents antibacteriens
WO1999002525A1 (fr) * 1997-07-11 1999-01-21 Pharmacia & Upjohn Company Agents antibacteriens de type phenyloxazolidinones de thiadiazolyle et d'oxadiazolyle

Also Published As

Publication number Publication date
GB0118407D0 (en) 2001-09-19
WO2003011859A2 (fr) 2003-02-13

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