WO2003011126A1 - Appareil et procedes d'analyse de tissus organiques - Google Patents
Appareil et procedes d'analyse de tissus organiques Download PDFInfo
- Publication number
- WO2003011126A1 WO2003011126A1 PCT/GB2002/003221 GB0203221W WO03011126A1 WO 2003011126 A1 WO2003011126 A1 WO 2003011126A1 GB 0203221 W GB0203221 W GB 0203221W WO 03011126 A1 WO03011126 A1 WO 03011126A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- analysis
- electromagnetic radiation
- bodily tissue
- guiding system
- tissue
- Prior art date
Links
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- 238000004624 confocal microscopy Methods 0.000 claims abstract description 7
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- 238000004477 FT-NIR spectroscopy Methods 0.000 claims description 2
- 238000001499 laser induced fluorescence spectroscopy Methods 0.000 claims description 2
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
Definitions
- ultrasound techniques there are a large number of analytical techniques which have been utilised, with varying degrees of success, for in vivo clinical monitoring. For example, there is considerable interest in medical applications of ultrasound and photoacoustic waves. This is because, in contrast to mterrogating techniques such as X-ray imaging and scintigraphy, ultrasound offers the possibility of interrogating a subject with no harmful side effects. Ultrasound imaging of cardiac structures, the vascular systems, the foetus and uterus, abdominal organs such as the liver, kidneys and gall bladder is known. Additionally, ultrasound measurements of the eye are known. It should be noted that, in addition to applications which are concerned solely with the generation of images, ultrasound techniques can provide information, albeit limited information, about the nature of the tissue being interrogated. Principally, such information relates to the elasticity of the interrogated tissue. However, it is not possible to provide detailed information concerning the state of the tissue under interrogation.
- the means for making clinically relevant measurements may use fluorescence microscopy.
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Medical Informatics (AREA)
- Biophysics (AREA)
- Pathology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Abstract
L'invention concerne un appareil d'analyse de tissus organiques comprenant: un moyen (10) permettant d'effectuer des mesures cliniquement pertinentes de ces tissus organiques à l'aide d'au moins deux techniques d'analyse sélectionnées parmi l'analyse photoacoustique, la spectroscopie par fluorescence; la spectroscopie Raman; la spectroscopie à rayonnement infrarouge; la microscopie confocale optique et la chromacité optique. Ce moyen (10) qui permet d'effectuer des mesures cliniquement pertinentes comprend une pluralité de sources de lumière (12, 14) qui délivrent un rayonnement électromagnétique servant à l'application des techniques d'analyse. Cet appareil comprend également un système guide de lumière (16, 18) qui est couplé à chaque source de lumière (12, 14) et permet d'orienter le rayonnement électromagnétique de chaque source de lumière vers le tissu organique tout en analysant sensiblement le long d'un passage commun de telle manière que le rayonnement électromagnétique provenant des sources de lumière (12, 14) émerge du système guide de lumière (16, 18) au niveau d'un point commun.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0118224A GB0118224D0 (en) | 2001-07-26 | 2001-07-26 | Apparatus and methods for analysing bodily tissue |
| GB0118224.5 | 2001-07-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| WO2003011126A1 true WO2003011126A1 (fr) | 2003-02-13 |
Family
ID=9919227
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/GB2002/003221 WO2003011126A1 (fr) | 2001-07-26 | 2002-07-15 | Appareil et procedes d'analyse de tissus organiques |
Country Status (2)
| Country | Link |
|---|---|
| GB (1) | GB0118224D0 (fr) |
| WO (1) | WO2003011126A1 (fr) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005104932A1 (fr) * | 2004-04-30 | 2005-11-10 | Koninklijke Philips Electronics N. V. | Tete de sonde utile pour l'analyse spectroscopique d'un fluide |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5293872A (en) * | 1991-04-03 | 1994-03-15 | Alfano Robert R | Method for distinguishing between calcified atherosclerotic tissue and fibrous atherosclerotic tissue or normal cardiovascular tissue using Raman spectroscopy |
| US5348002A (en) * | 1992-04-23 | 1994-09-20 | Sirraya, Inc. | Method and apparatus for material analysis |
| WO1999027848A1 (fr) * | 1997-12-02 | 1999-06-10 | Abbott Laboratories | Detecteur multiplex et procede d'utilisation |
-
2001
- 2001-07-26 GB GB0118224A patent/GB0118224D0/en not_active Ceased
-
2002
- 2002-07-15 WO PCT/GB2002/003221 patent/WO2003011126A1/fr not_active Application Discontinuation
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5293872A (en) * | 1991-04-03 | 1994-03-15 | Alfano Robert R | Method for distinguishing between calcified atherosclerotic tissue and fibrous atherosclerotic tissue or normal cardiovascular tissue using Raman spectroscopy |
| US5348002A (en) * | 1992-04-23 | 1994-09-20 | Sirraya, Inc. | Method and apparatus for material analysis |
| WO1999027848A1 (fr) * | 1997-12-02 | 1999-06-10 | Abbott Laboratories | Detecteur multiplex et procede d'utilisation |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005104932A1 (fr) * | 2004-04-30 | 2005-11-10 | Koninklijke Philips Electronics N. V. | Tete de sonde utile pour l'analyse spectroscopique d'un fluide |
| JP2007535356A (ja) * | 2004-04-30 | 2007-12-06 | コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ | 流体の分光分析に対するプローブヘッド |
| US8406835B2 (en) | 2004-04-30 | 2013-03-26 | Koninklijke Philips Electronics N.V. | Probe head for spectroscopic analysis of a fluid |
Also Published As
| Publication number | Publication date |
|---|---|
| GB0118224D0 (en) | 2001-09-19 |
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