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WO2003008582A1 - Nouvelle proteine d'origine humaine se liant avec la sphingosine kinase et polynucleotide codant pour cette proteine - Google Patents

Nouvelle proteine d'origine humaine se liant avec la sphingosine kinase et polynucleotide codant pour cette proteine Download PDF

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Publication number
WO2003008582A1
WO2003008582A1 PCT/JP2002/007352 JP0207352W WO03008582A1 WO 2003008582 A1 WO2003008582 A1 WO 2003008582A1 JP 0207352 W JP0207352 W JP 0207352W WO 03008582 A1 WO03008582 A1 WO 03008582A1
Authority
WO
WIPO (PCT)
Prior art keywords
protein
sphingosine kinase
polynucleotide encoding
novel human
kinase
Prior art date
Application number
PCT/JP2002/007352
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English (en)
Japanese (ja)
Inventor
Shun-Ichi Nakamura
Taro Okada
Original Assignee
The New Industry Research Organization
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The New Industry Research Organization filed Critical The New Industry Research Organization
Priority to JP2003514898A priority Critical patent/JP4491567B2/ja
Publication of WO2003008582A1 publication Critical patent/WO2003008582A1/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

L'invention concerne une nouvelle protéine : RPK118, isolée dans le cerveau humain, qui se lie avec la sphingosine kinase 1. On estime que cette protéine se lie avec la sphingosine kinase 1 du côté C-terminal du domaine P-kinase et transporte la sphingosine kinase 1 jusqu'à un site spécifique à l'intérieur d'une cellule via le domaine PX et le domaine ESP, et sert ainsi de protéine de tri.
PCT/JP2002/007352 2001-07-19 2002-07-19 Nouvelle proteine d'origine humaine se liant avec la sphingosine kinase et polynucleotide codant pour cette proteine WO2003008582A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2003514898A JP4491567B2 (ja) 2001-07-19 2002-07-19 ヒト由来のスフィンゴシン・キナーゼ１に結合する新規タンパク質、及び当該タンパク質をコードするポリヌクレオチド

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2001-220516 2001-07-19
JP2001220516 2001-07-19

Publications (1)

Publication Number Publication Date
WO2003008582A1 true WO2003008582A1 (fr) 2003-01-30

Family

ID=19054325

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2002/007352 WO2003008582A1 (fr) 2001-07-19 2002-07-19 Nouvelle proteine d'origine humaine se liant avec la sphingosine kinase et polynucleotide codant pour cette proteine

Country Status (2)

Country Link
JP (1) JP4491567B2 (fr)
WO (1) WO2003008582A1 (fr)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997033909A2 (fr) * 1996-03-15 1997-09-18 Corixa Corporation Composes et methodes d'immunotherapie et d'immunodiagnostic pour le cancer de la prostate
WO1999057144A2 (fr) * 1998-05-05 1999-11-11 Incyte Pharmaceuticals, Inc. Molecules de regulateur de transcription humaine
WO2000073469A2 (fr) * 1999-05-28 2000-12-07 Sugen, Inc. Proteines kinases
WO2002006330A2 (fr) * 2000-07-18 2002-01-24 Millennium Pharmaceuticals, Inc. Nouvelles molecules humaines de proteines kinases, 13237,18480,2245 ou 16228, et utilisations correspondantes

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997033909A2 (fr) * 1996-03-15 1997-09-18 Corixa Corporation Composes et methodes d'immunotherapie et d'immunodiagnostic pour le cancer de la prostate
WO1999057144A2 (fr) * 1998-05-05 1999-11-11 Incyte Pharmaceuticals, Inc. Molecules de regulateur de transcription humaine
WO2000073469A2 (fr) * 1999-05-28 2000-12-07 Sugen, Inc. Proteines kinases
WO2002006330A2 (fr) * 2000-07-18 2002-01-24 Millennium Pharmaceuticals, Inc. Nouvelles molecules humaines de proteines kinases, 13237,18480,2245 ou 16228, et utilisations correspondantes

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
COMPLETE CDS, 4 March 2002 (2002-03-04) *
DATABASE BIOSIS [online] HAYASHI S. ET AL.: "Identification and characterization of RPK118, a novel sphingosine kinase-1-binding protein", XP002958920, Database accession no. 2002:535465 *
DATABASE GENBANK [online] GUO J.H. ET AL.: "Homo sapiens RSK-like protein (RPK118) mRNA", XP002958921, Database accession no. (AF477978) *
J. BIOL. CHEM., vol. 277, no. 36, 6 September 2002 (2002-09-06), pages 33319 - 33324 *
KOHAMA T. ET AL.: "Molecular cloning and functional characterization of murine sphingosine kinase", J. BIOL. CHEM., vol. 273, no. 37, 11 September 1998 (1998-09-11), pages 23722 - 23728, XP002150781 *
ZHANG H. ET AL.: "Cloning, characterization and chromosome mapping of RPS6KC1, a novel putative member of the ribosome protein S6 kinase family, to chromosome 12q21-q13.1", GENOMICS, vol. 61, no. 3, 1 November 1999 (1999-11-01), pages 314 - 318, XP002165840 *

Also Published As

Publication number Publication date
JP4491567B2 (ja) 2010-06-30
JPWO2003008582A1 (ja) 2004-11-11

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