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WO2003094843A3 - Proteines d'adhesion cellulaire et a matrice extracellulaire - Google Patents

Proteines d'adhesion cellulaire et a matrice extracellulaire Download PDF

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Publication number
WO2003094843A3
WO2003094843A3 PCT/US2003/014076 US0314076W WO03094843A3 WO 2003094843 A3 WO2003094843 A3 WO 2003094843A3 US 0314076 W US0314076 W US 0314076W WO 03094843 A3 WO03094843 A3 WO 03094843A3
Authority
WO
WIPO (PCT)
Prior art keywords
extracellular matrix
cell adhesion
matrix proteins
cadecm
polynucleotides
Prior art date
Application number
PCT/US2003/014076
Other languages
English (en)
Other versions
WO2003094843A2 (fr
Inventor
Reena Khare
Vicki S Elliott
Joseph P Marquis
Jayalaxmi Ramkumar
Narinder K Chawla
Patricia M Mason
April J A Hafalia
Anita Swarnakar
Pei Jin
Shanya D Becha
Amy E Kable
Uyen K Tran
Mariah R Baughn
Neil Burford
Richard C Graul
Brooke M Emerling
William W Sprague
Jennifer A Griffin
Craig H Ison
Original Assignee
Incyte Corp
Reena Khare
Vicki S Elliott
Joseph P Marquis
Jayalaxmi Ramkumar
Narinder K Chawla
Patricia M Mason
April J A Hafalia
Anita Swarnakar
Pei Jin
Shanya D Becha
Amy E Kable
Uyen K Tran
Mariah R Baughn
Neil Burford
Richard C Graul
Brooke M Emerling
William W Sprague
Jennifer A Griffin
Craig H Ison
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Corp, Reena Khare, Vicki S Elliott, Joseph P Marquis, Jayalaxmi Ramkumar, Narinder K Chawla, Patricia M Mason, April J A Hafalia, Anita Swarnakar, Pei Jin, Shanya D Becha, Amy E Kable, Uyen K Tran, Mariah R Baughn, Neil Burford, Richard C Graul, Brooke M Emerling, William W Sprague, Jennifer A Griffin, Craig H Ison filed Critical Incyte Corp
Priority to AU2003228872A priority Critical patent/AU2003228872A1/en
Priority to US10/513,957 priority patent/US20070124581A1/en
Publication of WO2003094843A2 publication Critical patent/WO2003094843A2/fr
Publication of WO2003094843A3 publication Critical patent/WO2003094843A3/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Les différentes variantes de l'invention portent sur les protéines humaines CADECM (d'adhésion cellulaire et à matrice extracellulaire) et sur les polynucléotides qui les identifient et codent pour elles. Certaines de ces variantes portent sur des vecteurs d'expression, des cellules hôtes, des anticorps, des agonistes et des antagonistes. D'autres variantes portent sur des méthodes de traitement, diagnostic ou prévention de troubles associés à l'expression aberrante de CADECM.
PCT/US2003/014076 1992-05-17 2003-05-06 Proteines d'adhesion cellulaire et a matrice extracellulaire WO2003094843A2 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU2003228872A AU2003228872A1 (en) 2002-05-10 2003-05-06 Cell adhesion and extracellular matrix proteins
US10/513,957 US20070124581A1 (en) 1992-05-17 2003-05-06 Cell adhesion and extracellular matrix proteins

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US37984002P 2002-05-10 2002-05-10
US60/379,840 2002-05-10
US38129102P 2002-05-17 2002-05-17
US60/381,291 2002-05-17
US38318302P 2002-05-24 2002-05-24
US60/383,183 2002-05-24
US39414602P 2002-07-05 2002-07-05
US60/394,146 2002-07-05

Publications (2)

Publication Number Publication Date
WO2003094843A2 WO2003094843A2 (fr) 2003-11-20
WO2003094843A3 true WO2003094843A3 (fr) 2005-01-20

Family

ID=29424759

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2003/014076 WO2003094843A2 (fr) 1992-05-17 2003-05-06 Proteines d'adhesion cellulaire et a matrice extracellulaire

Country Status (2)

Country Link
AU (1) AU2003228872A1 (fr)
WO (1) WO2003094843A2 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2345256T3 (es) 2003-10-10 2010-09-20 Deutsches Krebsforschungszentrum Composiciones para diagnosis y terapia de enfermedades asociadas con la expresion aberrante de futrinas (r-espondinas) y/o wnt.
GB0520365D0 (en) * 2005-10-06 2005-11-16 Medical Res Council Crystal structure of CD44 and its use
WO2008012362A2 (fr) * 2006-07-27 2008-01-31 Oxford Genome Sciences (Uk) Ltd Nouvelles protéines isoformes et leur utilisation
PL2081586T5 (pl) 2006-10-20 2019-04-30 Deutsches Krebsforschungszentrum Stiftung Des Oeffentlichen Rechts Rspondyny jako modulatory angiogenezy i waskulogenezy

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002010449A2 (fr) * 2000-07-28 2002-02-07 Compugen Inc. Bibliotheque d'oligonucleotides destinee a detecter des transcrits d'arn et des variantes d'epissure qui garnissent un transcriptome
WO2002079404A2 (fr) * 2001-03-29 2002-10-10 Incyte Genomics, Inc. Proteines associees au cytosquelette

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002010449A2 (fr) * 2000-07-28 2002-02-07 Compugen Inc. Bibliotheque d'oligonucleotides destinee a detecter des transcrits d'arn et des variantes d'epissure qui garnissent un transcriptome
WO2002079404A2 (fr) * 2001-03-29 2002-10-10 Incyte Genomics, Inc. Proteines associees au cytosquelette

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
DAVIS ET AL.: "Molecular composition of the node of Ranvier: identification of ankyrinbinding cell adhesion molecules neurofascin (mucin+/third FNIII domain-) and NrCAM at nodal axon segments", J CELL BIOL., vol. 135, no. 5, December 1996 (1996-12-01), pages 1355 - 1367, XP002066829 *
DAVIS ET AL: "Ankyrin-binding proteins related to nervous system cell adhesion molecules: candidates to provide transmembrane and intercellular connections in adult brain", J CELL BIOL., vol. 121, no. 1, April 1993 (1993-04-01), pages 121 - 133, XP002982416 *
HORTSCH M.: "Structural and functional evolution of the L1 family: are four adhesion molecules better than one?", MOL CELL NEUROSCI., vol. 15, no. 1, January 2000 (2000-01-01), pages 1 - 10, XP002982417 *
HORTSCH M.: "The L1 family of neural cell adhesion molecules: old proteins performing new tricks", NEURON, vol. 17, no. 4, October 1996 (1996-10-01), pages 587 - 593, XP002982418 *

Also Published As

Publication number Publication date
AU2003228872A1 (en) 2003-11-11
AU2003228872A8 (en) 2003-11-11
WO2003094843A2 (fr) 2003-11-20

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