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WO2003066804A3 - Thermus scotoductus nucleic acid polymerases - Google Patents

Thermus scotoductus nucleic acid polymerases Download PDF

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Publication number
WO2003066804A3
WO2003066804A3 PCT/US2002/029102 US0229102W WO03066804A3 WO 2003066804 A3 WO2003066804 A3 WO 2003066804A3 US 0229102 W US0229102 W US 0229102W WO 03066804 A3 WO03066804 A3 WO 03066804A3
Authority
WO
WIPO (PCT)
Prior art keywords
nucleic acid
thermus scotoductus
acid polymerases
scotoductus
thermus
Prior art date
Application number
PCT/US2002/029102
Other languages
French (fr)
Other versions
WO2003066804A2 (en
Inventor
Elena V Bolchakova
James E Rozzelle
Original Assignee
Applera Corp
Elena V Bolchakova
James E Rozzelle
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Applera Corp, Elena V Bolchakova, James E Rozzelle filed Critical Applera Corp
Priority to JP2003566155A priority Critical patent/JP2005516611A/en
Priority to AU2002366438A priority patent/AU2002366438A1/en
Priority to EP02805994A priority patent/EP1466013A4/en
Priority to CA002459718A priority patent/CA2459718A1/en
Publication of WO2003066804A2 publication Critical patent/WO2003066804A2/en
Priority to US10/799,369 priority patent/US20050042629A1/en
Publication of WO2003066804A3 publication Critical patent/WO2003066804A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1241—Nucleotidyltransferases (2.7.7)
    • C12N9/1252—DNA-directed DNA polymerase (2.7.7.7), i.e. DNA replicase

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

The invention provides nucleic acids and polypeptides for a nucleic acid polymerase from a thermophilic organism, Thermus scotoductus. The invention also provides methods for using these nucleic acids and polypeptides.
PCT/US2002/029102 2001-09-14 2002-09-13 Thermus scotoductus nucleic acid polymerases WO2003066804A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
JP2003566155A JP2005516611A (en) 2001-09-14 2002-09-13 THERMUSSCOTODUCTUS NUCLEIC ACID POLYMERASE
AU2002366438A AU2002366438A1 (en) 2001-09-14 2002-09-13 Thermus scotoductus nucleic acid polymerases
EP02805994A EP1466013A4 (en) 2001-09-14 2002-09-13 Thermus scotoductus nucleic acid polymerases
CA002459718A CA2459718A1 (en) 2001-09-14 2002-09-13 Thermus scotoductus nucleic acid polymerases
US10/799,369 US20050042629A1 (en) 2002-09-13 2004-03-12 Thermus scotoductus nucleic acid polymerases

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US32221801P 2001-09-14 2001-09-14
US60/322,218 2001-09-14
US33448901P 2001-11-30 2001-11-30
US60/334,489 2001-11-30

Publications (2)

Publication Number Publication Date
WO2003066804A2 WO2003066804A2 (en) 2003-08-14
WO2003066804A3 true WO2003066804A3 (en) 2004-08-12

Family

ID=27737292

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/029102 WO2003066804A2 (en) 2001-09-14 2002-09-13 Thermus scotoductus nucleic acid polymerases

Country Status (5)

Country Link
EP (1) EP1466013A4 (en)
JP (1) JP2005516611A (en)
AU (1) AU2002366438A1 (en)
CA (1) CA2459718A1 (en)
WO (1) WO2003066804A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9587264B2 (en) 2001-09-14 2017-03-07 Applied Biosystems, Llc Thermus scotoductus nucleic acid polymerases

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2283789C (en) 1997-03-12 2005-07-05 The Perkin-Elmer Corporation Dna polymerases having improved labeled nucleotide incorporation properties
AU2002346498A1 (en) 2001-11-30 2003-06-17 Applera Corporation Thermus brockianus nucleic acid polymerases
CA2544841C (en) * 2003-11-03 2014-03-25 Medical Research Council Pola dna polymerases capable of abasic site bypass
JP4568571B2 (en) * 2004-10-06 2010-10-27 ユニバーサル・バイオ・リサーチ株式会社 Thermostable or thermoactive DNA polymerase and DNA encoding the same
US20060292578A1 (en) 2005-06-28 2006-12-28 Weidong Zheng DNA polymerase blends and mutant DNA polymerases
WO2007076464A2 (en) * 2005-12-22 2007-07-05 Ge Healthcare Bio-Sciences Corp. Thermostable dna polymerase from thermus filiformis
WO2007076461A1 (en) * 2005-12-22 2007-07-05 Ge Healthcare Bio-Sciences Corp. Thermostable dna polymerase from thermus scotoductus
US8685688B2 (en) * 2009-09-21 2014-04-01 University Of The Free State Isolation of a protein responsible for uranium (VI) reduction
EP2697372B1 (en) 2011-04-11 2015-12-16 Roche Diagnostics GmbH Dna polymerases with improved activity
EP2788480B1 (en) 2011-12-08 2019-01-16 Roche Diagnostics GmbH Dna polymerases with improved activity
CA2858264C (en) 2011-12-08 2018-01-02 F. Hoffmann-La Roche Ag Dna polymerases with improved activity
WO2013083263A1 (en) 2011-12-08 2013-06-13 Roche Diagnostics Gmbh Dna polymerases with improved activity

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5541311A (en) * 1992-12-07 1996-07-30 Third Wave Technologies, Inc. Nucleic acid encoding synthesis-deficient thermostable DNA polymerase
US6635463B2 (en) * 2000-05-24 2003-10-21 Third Wave Technologies, Inc. Enzymes for the detection of nucleic acid sequences

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2410072C (en) * 2000-05-24 2011-07-19 Third Wave Technologies, Inc. Polymerase cleavage agents and detection of rna

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5541311A (en) * 1992-12-07 1996-07-30 Third Wave Technologies, Inc. Nucleic acid encoding synthesis-deficient thermostable DNA polymerase
US6635463B2 (en) * 2000-05-24 2003-10-21 Third Wave Technologies, Inc. Enzymes for the detection of nucleic acid sequences

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP1466013A4 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9587264B2 (en) 2001-09-14 2017-03-07 Applied Biosystems, Llc Thermus scotoductus nucleic acid polymerases

Also Published As

Publication number Publication date
JP2005516611A (en) 2005-06-09
AU2002366438A1 (en) 2003-09-02
WO2003066804A2 (en) 2003-08-14
EP1466013A4 (en) 2006-09-06
EP1466013A2 (en) 2004-10-13
CA2459718A1 (en) 2003-08-14

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