+

WO2003066086A3 - Proteins involved in the regulation of energy homeostatis - Google Patents

Proteins involved in the regulation of energy homeostatis Download PDF

Info

Publication number
WO2003066086A3
WO2003066086A3 PCT/EP2003/001094 EP0301094W WO03066086A3 WO 2003066086 A3 WO2003066086 A3 WO 2003066086A3 EP 0301094 W EP0301094 W EP 0301094W WO 03066086 A3 WO03066086 A3 WO 03066086A3
Authority
WO
WIPO (PCT)
Prior art keywords
regulation
proteins involved
energy
homeostatis
energy homeostatis
Prior art date
Application number
PCT/EP2003/001094
Other languages
French (fr)
Other versions
WO2003066086A2 (en
Inventor
Karsten Eulenberg
Guenter Broenner
Arndt Steuernagel
Martin Meise
Thomas Haeder
Original Assignee
Develogen Ag
Karsten Eulenberg
Guenter Broenner
Arndt Steuernagel
Martin Meise
Thomas Haeder
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Develogen Ag, Karsten Eulenberg, Guenter Broenner, Arndt Steuernagel, Martin Meise, Thomas Haeder filed Critical Develogen Ag
Priority to AU2003226973A priority Critical patent/AU2003226973A1/en
Publication of WO2003066086A2 publication Critical patent/WO2003066086A2/en
Publication of WO2003066086A3 publication Critical patent/WO2003066086A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/45—Transferases (2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The present invention discloses casein kinase 1 gamma, GABARAP, PA2G4, MOCS1, CDC10, PK, calreticulin, and/or homologous proteins regulating the energy homeostasis and the metabolism of triglycerides, and polynucleotides, which identify and encode the proteins disclosed in this invention. The invention also relates to the use of these sequences in the diagnosis, study, prevention, and treatment of metabolic diseases and disorders.
PCT/EP2003/001094 2002-02-04 2003-02-04 Proteins involved in the regulation of energy homeostatis WO2003066086A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2003226973A AU2003226973A1 (en) 2002-02-04 2003-02-04 Proteins involved in the regulation of energy homeostatis

Applications Claiming Priority (12)

Application Number Priority Date Filing Date Title
EP02002548 2002-02-04
EP02002548.2 2002-02-04
EP02002707 2002-02-06
EP02002707.4 2002-02-06
EP02002891.6 2002-02-08
EP02002891 2002-02-08
EP02003748 2002-02-19
EP02003748.7 2002-02-19
EP02004667.8 2002-02-28
EP02004667 2002-02-28
EP02022101 2002-10-02
EP02022101.6 2002-10-02

Publications (2)

Publication Number Publication Date
WO2003066086A2 WO2003066086A2 (en) 2003-08-14
WO2003066086A3 true WO2003066086A3 (en) 2004-01-22

Family

ID=27739472

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2003/001094 WO2003066086A2 (en) 2002-02-04 2003-02-04 Proteins involved in the regulation of energy homeostatis

Country Status (2)

Country Link
AU (1) AU2003226973A1 (en)
WO (1) WO2003066086A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2561746A1 (en) * 2003-12-12 2005-06-23 The University Of Manitoba Methods and compounds for modulating triglyceride and vldl secretion
EP3049532A4 (en) * 2013-09-25 2017-07-05 The Institute for Systems Biology Markers for amyotrophic lateral sclerosis (als) and presymptomatic alzheimer's disease (psad)
CN105063056A (en) * 2015-09-20 2015-11-18 查文娟 Aptamer capable of being specifically combined with cancer marker calreticulin and kit
PL3445406T3 (en) 2016-04-20 2022-02-07 Centro De Investigaciones Energéticas, Medioambientales Y Tecnológicas, O.A., M.P. Compositions and methods for enhanced gene expression of pklr
BR112020007444A2 (en) 2017-10-16 2020-10-20 Centro de Investigaciones Energeticas, Medioambientales Y Tecnologicas, O.A., M.P. lentiviral vectors for pklr release to treat pyruvate kinase deficiency

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001096547A2 (en) * 2000-06-15 2001-12-20 Incyte Genomics, Inc. Human kinases
WO2002046384A2 (en) * 2000-12-06 2002-06-13 Incyte Genomics, Inc. Kinases and phosphatases sequences, and use thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001096547A2 (en) * 2000-06-15 2001-12-20 Incyte Genomics, Inc. Human kinases
WO2002046384A2 (en) * 2000-12-06 2002-06-13 Incyte Genomics, Inc. Kinases and phosphatases sequences, and use thereof

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
JEFFERSON L S ET AL: "Glycogen synthase kinase-3 is the predominant insulin-regulated eukaryotic initiation factor 2B kinase in skeletal muscle.", THE INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY. ENGLAND JAN 1999, vol. 31, no. 1, January 1999 (1999-01-01), pages 191 - 200, XP002250401, ISSN: 1357-2725 *
ROHER N ET AL: "Protein kinase CK2 is altered in insulin-resistant genetically obese (fa/fa) rats", FEBS LETTERS, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL, vol. 437, no. 3, 23 October 1998 (1998-10-23), pages 211 - 215, XP004258526, ISSN: 0014-5793 *

Also Published As

Publication number Publication date
WO2003066086A2 (en) 2003-08-14
AU2003226973A1 (en) 2003-09-02

Similar Documents

Publication Publication Date Title
Austin et al. Role of hyperhomocysteinemia in endothelial dysfunction and atherothrombotic disease
PT1511710E (en) Compounds, compositions and methods for the treatment of amyloid diseases and synucleinopathies such as alzheimer s disease, type 2 diabetes, and parkinson s disease
HK1063012A1 (en) Napthoquinone derivatives as inhibitors of tau aggregation for the treatment of alzheimer's and related neurodegenerative disorders
WO2003037362A3 (en) Mnk kinase homologous proteins involved in the regulation of energy homeostasis and organelle metabolism
WO2001060990A3 (en) Sphingosine kinases
WO2003066086A3 (en) Proteins involved in the regulation of energy homeostatis
WO2003061681A3 (en) Proteins involved in the regulation of energy homeostasis and organelle metabolism
WO2004015060A3 (en) Therapeutic polypeptides, nucleic acids encoding same, and methods of use
WO2002068652A3 (en) Nov-x proteins and nucleic acids encoding same
WO2002079398A3 (en) Therapeutic polypeptides, nucleic acids encoding same, and methods of use
WO2004035082A3 (en) Proteins involved in the regulation of energy homeostasis
WO2002099116A3 (en) Therapeutic polypeptides, nucleic acids encoding same, and methods of use
WO2003075945A3 (en) Cg8327, cg10823, cg18418, cg15862, cg3768, cg11447 and cg16750 homologous proteins involved in the regulation of energy homeostasis
WO2003092715A3 (en) Proteins involved in the regulation of energy homeostasis
WO2004020465A3 (en) Proteins involved in the regulation of energy homeostasis
WO2004050007A3 (en) Mammalian bt-42 proteins involved in the regulation of energy homeostasis
WO2004016641A3 (en) Proteins involved in the regulation of energy homeostasis
WO2004047855A3 (en) Proteins involved in the regulation of energy homeostasis
WO2004054601A3 (en) Fwd, pp2c1, adk3, cg3860, cdk4, cg7134, eip75b involved in the regulation of energy homeostasis
WO2003030922A3 (en) Bestrophin and bestrophin homologous proteins involved in the regulation of energy homeostasis
WO2003074078A3 (en) Cg3842 homologous proteins involved in the regulation of energy homeostasis
WO2002030979A3 (en) Polypeptides homologous to thymosin, ephrin a receptors, and fibromodulin, and polynucleotides encoding same
WO2003084566A3 (en) Proteins involved in the regulation of energy homeostasis
WO2004002513A3 (en) Proteins involved in the regulation of energy homeostasis
WO2003103704A3 (en) L(2)44 dea, wunen-2, grapes, cg2221, cg1172, rutabaga, cg11940, facl involved in the regulation of energy homeostasis

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ OM PH PL PT RO RU SC SD SE SG SK SL TJ TM TN TR TT TZ UA UG US UZ VC VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LU MC NL PT SE SI SK TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
122 Ep: pct application non-entry in european phase
NENP Non-entry into the national phase

Ref country code: JP

WWW Wipo information: withdrawn in national office

Country of ref document: JP

点击 这是indexloc提供的php浏览器服务，不要输入任何密码和下载