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WO2003061718A3 - Articles medicaux a surfaces enzymatiques pour traitement localise - Google Patents

Articles medicaux a surfaces enzymatiques pour traitement localise Download PDF

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Publication number
WO2003061718A3
WO2003061718A3 PCT/US2003/002020 US0302020W WO03061718A3 WO 2003061718 A3 WO2003061718 A3 WO 2003061718A3 US 0302020 W US0302020 W US 0302020W WO 03061718 A3 WO03061718 A3 WO 03061718A3
Authority
WO
WIPO (PCT)
Prior art keywords
enzymes
enzymatic
medical article
medical articles
localized therapy
Prior art date
Application number
PCT/US2003/002020
Other languages
English (en)
Other versions
WO2003061718A2 (fr
Inventor
Douglas C Shepard
Original Assignee
Scimed Life Systems Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scimed Life Systems Inc filed Critical Scimed Life Systems Inc
Priority to EP03732067A priority Critical patent/EP1478412A2/fr
Priority to CA002478773A priority patent/CA2478773A1/fr
Priority to AU2003210630A priority patent/AU2003210630A1/en
Priority to JP2003561659A priority patent/JP2005532840A/ja
Publication of WO2003061718A2 publication Critical patent/WO2003061718A2/fr
Publication of WO2003061718A3 publication Critical patent/WO2003061718A3/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/227—Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/38—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Materials Engineering (AREA)
  • Dermatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Materials For Medical Uses (AREA)
  • Surgical Instruments (AREA)

Abstract

L'invention concerne un article médical enzymatiquement actif comprenant un article médical et une enzyme disposée au niveau ou au voisinage d'une surface de l'article médical de façon que cet article médical présente une surface enzymatiquement active. Par exemple, cette enzyme est choisie dans le groupe constitué par des enzymes protéases, des enzymes glycosidases, des enzymes dégradant les esters de cholestérol, des enzymes convertissant l'hydrocortisone en cortisone, des enzymes dégradant l'oxalate, ainsi que des enzymes produisant du NO à partir de l'arginine.
PCT/US2003/002020 2002-01-24 2003-01-23 Articles medicaux a surfaces enzymatiques pour traitement localise WO2003061718A2 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
EP03732067A EP1478412A2 (fr) 2002-01-24 2003-01-23 Articles medicaux a surfaces enzymatiques pour traitement localise
CA002478773A CA2478773A1 (fr) 2002-01-24 2003-01-23 Articles medicaux a surfaces enzymatiques pour traitement localise
AU2003210630A AU2003210630A1 (en) 2002-01-24 2003-01-23 Medical articles having enzymatic surfaces for localized therapy
JP2003561659A JP2005532840A (ja) 2002-01-24 2003-01-23 局所的治療のための酵素表面を有する医療器具

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/057,596 US7407668B2 (en) 2002-01-24 2002-01-24 Medical articles having enzymatic surfaces for localized therapy
US10/057,596 2002-01-24

Publications (2)

Publication Number Publication Date
WO2003061718A2 WO2003061718A2 (fr) 2003-07-31
WO2003061718A3 true WO2003061718A3 (fr) 2003-12-04

Family

ID=22011582

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2003/002020 WO2003061718A2 (fr) 2002-01-24 2003-01-23 Articles medicaux a surfaces enzymatiques pour traitement localise

Country Status (6)

Country Link
US (2) US7407668B2 (fr)
EP (1) EP1478412A2 (fr)
JP (1) JP2005532840A (fr)
AU (1) AU2003210630A1 (fr)
CA (1) CA2478773A1 (fr)
WO (1) WO2003061718A2 (fr)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8486389B2 (en) 1997-05-23 2013-07-16 Oxthera, Inc. Compositions and methods for treating or preventing oxalate-related disease
US7569342B2 (en) 1997-12-10 2009-08-04 Sierra Molecular Corp. Removal of molecular assay interferences
US9114199B2 (en) * 2003-07-31 2015-08-25 Boston Scientific Scimed, Inc. Implantable or insertable medical devices containing acrylic copolymer for controlled delivery of therapeutic agent
US7320675B2 (en) 2003-08-21 2008-01-22 Cardiac Pacemakers, Inc. Method and apparatus for modulating cellular metabolism during post-ischemia or heart failure
JP2007508121A (ja) * 2003-10-14 2007-04-05 キューブ メディカル エーエス 血管形成術用バルーン
CA2448995A1 (fr) * 2003-11-12 2005-05-12 James Keenan Dispositif et methode pour attirer les cellules malades et les substances etrangeres
US7840263B2 (en) * 2004-02-27 2010-11-23 Cardiac Pacemakers, Inc. Method and apparatus for device controlled gene expression
EP1750782A1 (fr) * 2004-04-29 2007-02-14 Cube Medical A/S Ballonnet a utiliser dans l'angioplastie, comportant une couche exterieure de nanofibres
EP1755655A4 (fr) * 2004-05-07 2011-03-30 Oxthera Inc Procedes et compositions de reduction des concentrations d'oxalate
US7764995B2 (en) * 2004-06-07 2010-07-27 Cardiac Pacemakers, Inc. Method and apparatus to modulate cellular regeneration post myocardial infarct
US7729761B2 (en) 2004-07-14 2010-06-01 Cardiac Pacemakers, Inc. Method and apparatus for controlled gene or protein delivery
US7621906B2 (en) * 2004-08-25 2009-11-24 Cardiac Pacemakers, Inc. Method and apparatus to deliver drug and pacing therapy for treatment of cardiac disorders
PL1962873T3 (pl) * 2005-12-14 2014-03-31 Oxthera Intellectual Property Ab Kompozycje farmaceutyczne zawierające bakterie zmniejszające ilość szczawianu
CN101405022A (zh) * 2005-12-16 2009-04-08 奥克斯赛拉公司 用于减少草酸盐的组合物和方法
WO2010014541A2 (fr) * 2008-07-28 2010-02-04 Alnara Pharmaceuticals, Inc. Compositions et procédé pour le traitement de l'hypercholestérolémie
BRPI0900858A2 (pt) * 2009-04-23 2011-05-03 Clinica De Andrologia E Urologia Vera Cruz Ltda composição farmacêutica carreadora de substáncias ativas
CN115607738B (zh) * 2022-10-31 2023-07-14 中国人民解放军陆军军医大学 基于仿生内皮细胞抗血栓功能的心血管植入物及其制备方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4378435A (en) * 1979-10-27 1983-03-29 Unitika, Ltd. Process for providing enzyme activity to a solid surface

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3826678A (en) * 1972-06-06 1974-07-30 Atomic Energy Commission Method for preparation of biocompatible and biofunctional materials and product thereof
US4277560A (en) * 1978-10-24 1981-07-07 Technicon Instruments Corporation Enzyme immunoassays using immobilized reagents in a flowing stream
US4525456A (en) * 1982-11-08 1985-06-25 Uop Inc. Support matrix and immobilized enzyme system
JPS59204601A (ja) * 1983-05-09 1984-11-20 Unitika Ltd 生理活性を有する成形体の製造方法
GB2150833B (en) * 1983-12-08 1987-04-15 Ceskoslovenska Akademie Ved Proteolytic wounds dressing
US4757014A (en) * 1985-11-08 1988-07-12 Minnesota Mining And Manufacturing Company Immobilization of biologically active protein on a polymeric fibrous support
IL78826A (en) * 1986-05-19 1991-05-12 Yissum Res Dev Co Precursor composition for the preparation of a biodegradable implant for the sustained release of an active material and such implants prepared therefrom
US4885250A (en) * 1987-03-02 1989-12-05 E. I. Du Pont De Nemours And Company Enzyme immobilization and bioaffinity separations with perfluorocarbon polymer-based supports
JPH05310868A (ja) * 1992-05-11 1993-11-22 Japan Synthetic Rubber Co Ltd 医療材用組成物
NO931809L (no) * 1993-05-19 1994-11-21 Norsk Hydro As Hemofilter
US5505713A (en) * 1994-04-01 1996-04-09 Minimed Inc. Indwelling catheter with stable enzyme coating
US6043098A (en) * 1994-05-17 2000-03-28 Spallholz; Julian E. Method for the preparation of free radical pharmaceuticals, diagnostics and devices using selenium conjugates
US5759836A (en) * 1995-03-27 1998-06-02 Hospital For Joint Diseases Osteoarthritis-associated inducable isoform of nitric oxide synthetase
US6033719A (en) * 1996-04-25 2000-03-07 Medtronic, Inc. Method for covalent attachment of biomolecules to surfaces of medical devices
US5741331A (en) * 1996-07-29 1998-04-21 Corvita Corporation Biostable elastomeric polymers having quaternary carbons
JPH10328293A (ja) * 1997-06-04 1998-12-15 Unitika Ltd 医療用具及びその製造方法
US6177282B1 (en) * 1997-08-12 2001-01-23 Mcintyre John A. Antigens embedded in thermoplastic
US6569688B2 (en) * 1997-08-26 2003-05-27 Technion Research & Development Foundation Ltd. Intravascular apparatus method
US6024918A (en) * 1998-03-13 2000-02-15 Medtronic, Inc. Method for attachment of biomolecules to surfaces of medical devices

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4378435A (en) * 1979-10-27 1983-03-29 Unitika, Ltd. Process for providing enzyme activity to a solid surface

Also Published As

Publication number Publication date
JP2005532840A (ja) 2005-11-04
US20030138415A1 (en) 2003-07-24
AU2003210630A1 (en) 2003-09-02
WO2003061718A2 (fr) 2003-07-31
EP1478412A2 (fr) 2004-11-24
US7407668B2 (en) 2008-08-05
US20080292678A1 (en) 2008-11-27
CA2478773A1 (fr) 2003-07-31

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