WO2003041499A2 - Composes bactericides bases sur des complexes chelateurs - metaux et composition desinfectante - Google Patents
Composes bactericides bases sur des complexes chelateurs - metaux et composition desinfectante Download PDFInfo
- Publication number
- WO2003041499A2 WO2003041499A2 PCT/RU2002/000484 RU0200484W WO03041499A2 WO 2003041499 A2 WO2003041499 A2 WO 2003041499A2 RU 0200484 W RU0200484 W RU 0200484W WO 03041499 A2 WO03041499 A2 WO 03041499A2
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- WIPO (PCT)
- Prior art keywords
- ligand
- acid
- disinfectant
- complex
- bactericides
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- BCKXLBQYZLBQEK-KVVVOXFISA-M Sodium oleate Chemical compound [Na+].CCCCCCCC\C=C/CCCCCCCC([O-])=O BCKXLBQYZLBQEK-KVVVOXFISA-M 0.000 description 1
- 241000272534 Struthio camelus Species 0.000 description 1
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- PVRBHFSNIJZPHQ-UHFFFAOYSA-N acetic acid;n'-(2-aminoethyl)ethane-1,2-diamine Chemical compound CC(O)=O.CC(O)=O.CC(O)=O.CC(O)=O.NCCNCCN PVRBHFSNIJZPHQ-UHFFFAOYSA-N 0.000 description 1
- 239000011149 active material Substances 0.000 description 1
- 229910052783 alkali metal Inorganic materials 0.000 description 1
- 150000001340 alkali metals Chemical class 0.000 description 1
- 229910052784 alkaline earth metal Inorganic materials 0.000 description 1
- 150000001342 alkaline earth metals Chemical class 0.000 description 1
- 125000003545 alkoxy group Chemical group 0.000 description 1
- 125000000217 alkyl group Chemical group 0.000 description 1
- 229940064004 antiseptic throat preparations Drugs 0.000 description 1
- 235000009582 asparagine Nutrition 0.000 description 1
- 229960001230 asparagine Drugs 0.000 description 1
- PRORZGWHZXZQMV-UHFFFAOYSA-N azane;nitric acid Chemical compound N.O[N+]([O-])=O PRORZGWHZXZQMV-UHFFFAOYSA-N 0.000 description 1
- FVCHPLIQTBSXKX-UHFFFAOYSA-N azanium;2-[2-[bis(carboxymethyl)amino]ethyl-(carboxymethyl)amino]acetate Chemical class N.OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O FVCHPLIQTBSXKX-UHFFFAOYSA-N 0.000 description 1
- 239000002585 base Substances 0.000 description 1
- 238000003339 best practice Methods 0.000 description 1
- 230000003115 biocidal effect Effects 0.000 description 1
- 235000010633 broth Nutrition 0.000 description 1
- 125000004181 carboxyalkyl group Chemical group 0.000 description 1
- 239000005018 casein Substances 0.000 description 1
- BECPQYXYKAMYBN-UHFFFAOYSA-N casein, tech. Chemical compound NCCCCC(C(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(CC(C)C)N=C(O)C(CCC(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(C(C)O)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(COP(O)(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(N)CC1=CC=CC=C1 BECPQYXYKAMYBN-UHFFFAOYSA-N 0.000 description 1
- 235000021240 caseins Nutrition 0.000 description 1
- XMLNCADGRIEXPK-KUMOIWDRSA-M chembl2146143 Chemical compound [Br-].O([C@H]1C[C@H]2CC[C@@H](C1)[N+]2(C)C)C(=O)C(CO)C1=CC=CC=C1 XMLNCADGRIEXPK-KUMOIWDRSA-M 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- NEHMKBQYUWJMIP-NJFSPNSNSA-N chloro(114C)methane Chemical compound [14CH3]Cl NEHMKBQYUWJMIP-NJFSPNSNSA-N 0.000 description 1
- 230000007882 cirrhosis Effects 0.000 description 1
- 208000019425 cirrhosis of liver Diseases 0.000 description 1
- 239000000571 coke Substances 0.000 description 1
- 230000002860 competitive effect Effects 0.000 description 1
- 150000004695 complexes Chemical class 0.000 description 1
- 238000013329 compounding Methods 0.000 description 1
- 239000012141 concentrate Substances 0.000 description 1
- 235000008504 concentrate Nutrition 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- VVYPIVJZLVJPGU-UHFFFAOYSA-L copper;2-aminoacetate Chemical compound [Cu+2].NCC([O-])=O.NCC([O-])=O VVYPIVJZLVJPGU-UHFFFAOYSA-L 0.000 description 1
- 235000018417 cysteine Nutrition 0.000 description 1
- XUJNEKJLAYXESH-UHFFFAOYSA-N cysteine Natural products SCC(N)C(O)=O XUJNEKJLAYXESH-UHFFFAOYSA-N 0.000 description 1
- 229960003067 cystine Drugs 0.000 description 1
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- 239000008367 deionised water Substances 0.000 description 1
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- 231100000676 disease causative agent Toxicity 0.000 description 1
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- ZSFDBVJMDCMTBM-UHFFFAOYSA-N ethane-1,2-diamine;phosphoric acid Chemical compound NCCN.OP(O)(O)=O ZSFDBVJMDCMTBM-UHFFFAOYSA-N 0.000 description 1
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- 239000000284 extract Substances 0.000 description 1
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- 102000034240 fibrous proteins Human genes 0.000 description 1
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- 238000013467 fragmentation Methods 0.000 description 1
- 238000006062 fragmentation reaction Methods 0.000 description 1
- 239000007789 gas Substances 0.000 description 1
- 235000013922 glutamic acid Nutrition 0.000 description 1
- 239000004220 glutamic acid Substances 0.000 description 1
- 235000011187 glycerol Nutrition 0.000 description 1
- 229960005150 glycerol Drugs 0.000 description 1
- 231100001261 hazardous Toxicity 0.000 description 1
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- 231100000283 hepatitis Toxicity 0.000 description 1
- 229910052739 hydrogen Inorganic materials 0.000 description 1
- 239000001257 hydrogen Substances 0.000 description 1
- 125000004435 hydrogen atom Chemical class [H]* 0.000 description 1
- WQYVRQLZKVEZGA-UHFFFAOYSA-N hypochlorite Chemical class Cl[O-] WQYVRQLZKVEZGA-UHFFFAOYSA-N 0.000 description 1
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- 230000000968 intestinal effect Effects 0.000 description 1
- 238000011835 investigation Methods 0.000 description 1
- 229910052742 iron Inorganic materials 0.000 description 1
- 239000004571 lime Substances 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 238000011068 loading method Methods 0.000 description 1
- 229940037627 magnesium lauryl sulfate Drugs 0.000 description 1
- HBNDBUATLJAUQM-UHFFFAOYSA-L magnesium;dodecyl sulfate Chemical compound [Mg+2].CCCCCCCCCCCCOS([O-])(=O)=O.CCCCCCCCCCCCOS([O-])(=O)=O HBNDBUATLJAUQM-UHFFFAOYSA-L 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 235000013372 meat Nutrition 0.000 description 1
- 229940050176 methyl chloride Drugs 0.000 description 1
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- 150000002894 organic compounds Chemical class 0.000 description 1
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- 239000002245 particle Substances 0.000 description 1
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- 229910052698 phosphorus Inorganic materials 0.000 description 1
- 239000011574 phosphorus Substances 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 230000000241 respiratory effect Effects 0.000 description 1
- 210000002345 respiratory system Anatomy 0.000 description 1
- 229910052709 silver Inorganic materials 0.000 description 1
- 239000004332 silver Substances 0.000 description 1
- 230000036556 skin irritation Effects 0.000 description 1
- 231100000475 skin irritation Toxicity 0.000 description 1
- WXMKPNITSTVMEF-UHFFFAOYSA-M sodium benzoate Chemical compound [Na+].[O-]C(=O)C1=CC=CC=C1 WXMKPNITSTVMEF-UHFFFAOYSA-M 0.000 description 1
- 239000004299 sodium benzoate Substances 0.000 description 1
- 235000010234 sodium benzoate Nutrition 0.000 description 1
- 159000000000 sodium salts Chemical class 0.000 description 1
- 230000000087 stabilizing effect Effects 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 230000003637 steroidlike Effects 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 125000001424 substituent group Chemical group 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 150000003871 sulfonates Chemical class 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
- 239000012209 synthetic fiber Substances 0.000 description 1
- 229920002994 synthetic fiber Polymers 0.000 description 1
- 229960002180 tetracycline Drugs 0.000 description 1
- 229930101283 tetracycline Natural products 0.000 description 1
- 235000019364 tetracycline Nutrition 0.000 description 1
- 150000003522 tetracyclines Chemical class 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 210000000115 thoracic cavity Anatomy 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 230000007704 transition Effects 0.000 description 1
- OUYCCCASQSFEME-UHFFFAOYSA-N tyrosine Natural products OC(=O)C(N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-UHFFFAOYSA-N 0.000 description 1
- 230000003253 viricidal effect Effects 0.000 description 1
- 230000003612 virological effect Effects 0.000 description 1
- 230000004584 weight gain Effects 0.000 description 1
- 235000019786 weight gain Nutrition 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N59/00—Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
- A01N59/16—Heavy metals; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
Definitions
- the invention relates to bactericidal substances and com pacts
- the quicker may be used as an antibacterial product.
- the company can be used in agriculture, in medicine, in
- the proposed offer may be used in
- CIRCUITS are compounds and compounds containing an “active” substance, such as
- the developed countries are the sodium salt of diethylisocyanate,
- Chloride (copyright certificate of the USSR ⁇ ° 1616898, 1990; copyright
- L 5 for white and brown pigs equal to 760 and 900 mg / kg, respectively.
- Disinfectants having a bactericidal effect are also described.
- Compound of metals is a bactericide, which is a hazard
- Composition including a compound of a metal with ⁇ -amino acid and
- the antimicrobial combination includes
- Obtained in an acidic environment is a mixture of metal and ⁇ -amino acid, as well as
- such a strong best-selling agent is like EDA, in full
- the product is a disinfectant that contains harmful substances
- EDA ethylenediaminetetoacetic acid
- sodium benzoate sodium benzoate
- Selective agents may be, for example, ethylenediaminetetoacetic acid (EDA), its salts,
- ⁇ the analogue is also referred to as the bactericide described above,
- bactericidal preparations including
- Bacteria vary between 5-30 minutes.
- Compounds are metal compounds, such as
- ammonia-acid complexes ammonia-nitrate and acetate
- the metal is based on the blocking of amino acid groups of the protein Businesses and fragmentation systems of microorganisms. In the first stage
- the molar ligand is replaced by an amino acid group protein, which
- the metal is based on the substitution of an amine group with a strong group
- the proposed bactericides are produced in an alkaline, rather than acid, complex.
- composition of basic and acidic centers aminogroups, carboxyalkyl-,
- alkylsulfonic-, alkylsulfonic groups alkylsulfonic groups.
- preferable compounds having a ligand alpha-amino acids having a ligand alpha-amino acids
- Fragments such as glycine, iminodiacetic and nitrous acetic
- the desired ligand uses bi-or multiple ligands
- anhydrous amino acids or imiodic acids including: anhydrous amino acids or imiodic acids, or
- alkylenediamine-polyacetic acids as well as substituted in the ⁇ -position ⁇
- the proposed bactericide contains in its composition:
- a metal one of the following: copper (II), zinc,
- Improving groups in particular, such as:
- leucine leucine, isoleucine, phenylalanine, tyrosine, ⁇ lina, ⁇ sy ⁇ lina, serine,
- cysteine cysteine
- cystine methinine
- liver asparagine
- the location of the large group is very flexible.
- the task that is being addressed is the proposed disinfection rate on
- a chelate complex In the case of a chelate complex, a chelate complex is used.
- the distributor uses distilled water.
- the proposed offer is a disinfectant.
- a prefabricated metal compound including fifteen
- a domestic ligand that possesses a natural source of foreign food that possesses a natural source of foreign food.
- the domestic ligand which possesses a good source of foreign food, is
- a beautiful ligand can be used by one of the bi 16
- solid ligands such as the anions of natural amino acids
- Residues of amino acid fragments without an amine-rich group Residues of amino acid fragments without an amine-rich group
- the domestic ligand which possesses a good source of foreign food, is
- a preferable ligand may be used by one of the other options.
- tropionine tropin, valine, alanine, glycine, arginine, histidine, or their mixture
- cetylpyridinium halides cetylpyridinium halides.
- the disinfecting equipment is available in the IV class of safety. Doses
- the proposed bacteria bacterium is in its own right.
- ammonia mono-, di- and ⁇ iethanolamines and ⁇ . ⁇ .
- the resulting bactericidal com pounds have ⁇ > 7.0.
- bactericidal exposures are those that interact (mixing)
- the ethylenediaminetaceous acid complex of zinc is known from the following
- alkylpyridinium in particular the halogenides of cetylpyridinium and
- Pulmonary disease ( ⁇ - ⁇ ) 0.5% - 95%
- cetylpyridinium and cetylmethylammonium are examples of cetylpyridinium and cetylmethylammonium.
- Bactericides on the basis of healthy metallurgical complexes may be
- the resulting bactericidal complexes have ⁇ > 7.0.
- the ligands used are suitable for the manufacture of materials
- Flask is poured with 1.22 cm of 25% ammonia solution of 15 ml of water and
- the number of microbodies in the extractor hood was 10 - 10
- bactericidal preparation is an example of
- the reactive activity is dominated by healthy complexes of metals and
- the perfect complex is due to the loading of the amine nitrogen atom. 25
- Bactericides on the basis of chelated metallocomplexes of metals can be used
- the flask is filled with 6.1 cm 3 of 25% ammonia solution of 25 ml of water and
- the mixture is mixed with 0.75 cm of a 25% ammonia solution in water. ⁇
- the Chemically Integrated Metal Compound which contains a ligand that is commercially available, has a good foreign water content of 30
- Example 8 Mix the ingredients as described in Example 2 in Example 8.
- the yellow complex compound of the metal containing a ligand that is commercially available, has a friendly foreign water 2 28
- ammonia of copper glycine showed a significant high activity in
- the device is intended for the disinfection of basic forms and species of the pathogen
- pathogens such as:
- viruses hepatitis, herpes, hypertrophy
- the application interval was as follows: -20 ° ⁇ to + 40 ° ⁇ ⁇
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Inorganic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Toxicology (AREA)
- Veterinary Medicine (AREA)
- Agronomy & Crop Science (AREA)
- Medicinal Chemistry (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2002363782A AU2002363782A1 (en) | 2001-11-12 | 2002-11-11 | Bactericides based on metal-chelate complexes and disinfecting composition |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
RU2001130337/15A RU2229897C2 (ru) | 2001-11-12 | 2001-11-12 | Бактерициды на основе хелатных комплексов металлов |
RU2001130337 | 2001-11-12 | ||
RU2002119628 | 2002-07-24 | ||
RU2002119628/13A RU2226109C1 (ru) | 2002-07-24 | 2002-07-24 | Дезинфицирующее средство (варианты) |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2003041499A2 true WO2003041499A2 (fr) | 2003-05-22 |
WO2003041499A3 WO2003041499A3 (fr) | 2003-09-18 |
Family
ID=26654104
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/RU2002/000484 WO2003041499A2 (fr) | 2001-11-12 | 2002-11-11 | Composes bactericides bases sur des complexes chelateurs - metaux et composition desinfectante |
Country Status (2)
Country | Link |
---|---|
AU (1) | AU2002363782A1 (fr) |
WO (1) | WO2003041499A2 (fr) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2005044287A1 (fr) * | 2003-11-11 | 2005-05-19 | Veckis Industries Ltd. | Composition desinfectante et ses procedes de fabrication et d'exploitation |
WO2006116983A3 (fr) * | 2005-04-30 | 2007-06-21 | Multibind Biotec Gmbh | Solutions de decontamination et leur utilisation pour denaturer, modifier, degrader, rendre solubles et eliminer des proteines, molecules d'acide nucleique et micro-organismes |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5198208A (en) * | 1987-07-16 | 1993-03-30 | Nycomed Imaging As | Aminopolycarboxylic acids and derivatives thereof |
RU2061497C1 (ru) * | 1992-04-26 | 1996-06-10 | Вадим Анатольевич Максимец | Дезинфицирующая композиция |
WO1997006237A1 (fr) * | 1995-08-09 | 1997-02-20 | The Procter & Gamble Company | Compositions de nettoyage et de sterilisation comportant un agent electrolytique renforçant la sterilisation |
DE19646759C2 (de) * | 1996-11-04 | 2003-01-09 | Schuelke & Mayr Gmbh | Verwendung eines optischen Aufhellers in einem Desinfektionsmittel |
JP3853985B2 (ja) * | 1998-08-03 | 2006-12-06 | 有限会社 健康百二十才 | 鉄イオン含有殺菌液 |
-
2002
- 2002-11-11 WO PCT/RU2002/000484 patent/WO2003041499A2/fr not_active Application Discontinuation
- 2002-11-11 AU AU2002363782A patent/AU2002363782A1/en not_active Abandoned
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2005044287A1 (fr) * | 2003-11-11 | 2005-05-19 | Veckis Industries Ltd. | Composition desinfectante et ses procedes de fabrication et d'exploitation |
JP2007510712A (ja) * | 2003-11-11 | 2007-04-26 | ベッキス インダストリーズ リミテッド | 殺菌組成物ならびにその作製方法および使用方法 |
WO2006116983A3 (fr) * | 2005-04-30 | 2007-06-21 | Multibind Biotec Gmbh | Solutions de decontamination et leur utilisation pour denaturer, modifier, degrader, rendre solubles et eliminer des proteines, molecules d'acide nucleique et micro-organismes |
US10980239B2 (en) | 2005-04-30 | 2021-04-20 | Multibind Biotec Gmbh | Decontamination solution and its use for denaturation, modification, degradation, solubilisation and removal of proteins, nucleic acid molecules and microorganisms |
Also Published As
Publication number | Publication date |
---|---|
AU2002363782A1 (en) | 2003-05-26 |
WO2003041499A3 (fr) | 2003-09-18 |
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