WO2003040334A3 - Methods for the identification of inhibitors of 4-coumarate-coa ligase expression or activity in plants - Google Patents
Methods for the identification of inhibitors of 4-coumarate-coa ligase expression or activity in plants Download PDFInfo
- Publication number
- WO2003040334A3 WO2003040334A3 PCT/US2002/035596 US0235596W WO03040334A3 WO 2003040334 A3 WO2003040334 A3 WO 2003040334A3 US 0235596 W US0235596 W US 0235596W WO 03040334 A3 WO03040334 A3 WO 03040334A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- identification
- activity
- methods
- coumarate
- expression
- Prior art date
Links
- 108010016192 4-coumarate-CoA ligase Proteins 0.000 title abstract 8
- 230000014509 gene expression Effects 0.000 title abstract 4
- 239000003112 inhibitor Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 230000012010 growth Effects 0.000 abstract 2
- 239000004009 herbicide Substances 0.000 abstract 2
- 101150029435 4CL gene Proteins 0.000 abstract 1
- 241000196324 Embryophyta Species 0.000 abstract 1
- 230000005764 inhibitory process Effects 0.000 abstract 1
- 230000008635 plant growth Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/93—Ligases (6)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
- C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
- C12N15/8274—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for herbicide resistance
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/25—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving enzymes not classifiable in groups C12Q1/26 - C12Q1/66
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/02—Screening involving studying the effect of compounds C on the interaction between interacting molecules A and B (e.g. A = enzyme and B = substrate for A, or A = receptor and B = ligand for the receptor)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/04—Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Cell Biology (AREA)
- Immunology (AREA)
- Plant Pathology (AREA)
- Medicinal Chemistry (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2002361590A AU2002361590A1 (en) | 2001-11-08 | 2002-11-06 | Methods for the identification of inhibitors of 4-coumarate-coa ligase expression or activity in plants |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US33795501P | 2001-11-08 | 2001-11-08 | |
US60/337,955 | 2001-11-08 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2003040334A2 WO2003040334A2 (en) | 2003-05-15 |
WO2003040334A3 true WO2003040334A3 (en) | 2003-11-20 |
Family
ID=23322753
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2002/035596 WO2003040334A2 (en) | 2001-11-08 | 2002-11-06 | Methods for the identification of inhibitors of 4-coumarate-coa ligase expression or activity in plants |
Country Status (2)
Country | Link |
---|---|
AU (1) | AU2002361590A1 (en) |
WO (1) | WO2003040334A2 (en) |
-
2002
- 2002-11-06 AU AU2002361590A patent/AU2002361590A1/en not_active Abandoned
- 2002-11-06 WO PCT/US2002/035596 patent/WO2003040334A2/en not_active Application Discontinuation
Non-Patent Citations (3)
Title |
---|
DATABASE PROTEIN [online] 18 August 2000 (2000-08-18), RIEGER M. ET AL., XP002963640, accession no. NCBI Database accession no. (T46131) * |
EHLTING J. ET AL.: "Three 4-coumarate: coenzyme a ligases in arabidopsis thaliana represent two evolutionarily divergent classes in angiosperms", THE PLANT JOURNAL, vol. 19, no. 1, 1999, pages 9 - 20, XP002963639 * |
VOO K.S. ET AL.: "4-Coumarate: coenzyme a ligase from loblolly pine xylem, isolation, characterization and complementary DNA cloning", PLANT PHYSIOLOGY, vol. 108, 1995, pages 85 - 97, XP002194496 * |
Also Published As
Publication number | Publication date |
---|---|
WO2003040334A2 (en) | 2003-05-15 |
AU2002361590A1 (en) | 2003-05-19 |
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