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WO2002034113A3 - Procedes et instruments destines au traitement de pseudarthrose - Google Patents

Procedes et instruments destines au traitement de pseudarthrose Download PDF

Info

Publication number
WO2002034113A3
WO2002034113A3 PCT/US2001/045479 US0145479W WO0234113A3 WO 2002034113 A3 WO2002034113 A3 WO 2002034113A3 US 0145479 W US0145479 W US 0145479W WO 0234113 A3 WO0234113 A3 WO 0234113A3
Authority
WO
WIPO (PCT)
Prior art keywords
pseudoarthrosis
instruments
drill
methods
treating
Prior art date
Application number
PCT/US2001/045479
Other languages
English (en)
Other versions
WO2002034113A2 (fr
Inventor
William F Mckay
Original Assignee
Sdgi Holdings Inc
William F Mckay
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sdgi Holdings Inc, William F Mckay filed Critical Sdgi Holdings Inc
Priority to CA002426402A priority Critical patent/CA2426402A1/fr
Priority to EP01988541A priority patent/EP1335771A4/fr
Priority to JP2002537173A priority patent/JP2004512078A/ja
Priority to AU2006902A priority patent/AU2006902A/xx
Priority to US10/399,836 priority patent/US8002775B2/en
Priority to AU2002220069A priority patent/AU2002220069B2/en
Publication of WO2002034113A2 publication Critical patent/WO2002034113A2/fr
Publication of WO2002034113A3 publication Critical patent/WO2002034113A3/fr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/44Joints for the spine, e.g. vertebrae, spinal discs
    • A61F2/4455Joints for the spine, e.g. vertebrae, spinal discs for the fusion of spinal bodies, e.g. intervertebral fusion of adjacent spinal bodies, e.g. fusion cages
    • A61F2/446Joints for the spine, e.g. vertebrae, spinal discs for the fusion of spinal bodies, e.g. intervertebral fusion of adjacent spinal bodies, e.g. fusion cages having a circular or elliptical cross-section substantially parallel to the axis of the spine, e.g. cylinders or frustocones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/46Special tools for implanting artificial joints
    • A61F2/4601Special tools for implanting artificial joints for introducing bone substitute, for implanting bone graft implants or for compacting them in the bone cavity
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2/44Joints for the spine, e.g. vertebrae, spinal discs
    • A61F2/442Intervertebral or spinal discs, e.g. resilient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/28Bones
    • A61F2002/2817Bone stimulation by chemical reactions or by osteogenic or biological products for enhancing ossification, e.g. by bone morphogenetic or morphogenic proteins [BMP] or by transforming growth factors [TGF]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30108Shapes
    • A61F2002/30199Three-dimensional shapes
    • A61F2002/30224Three-dimensional shapes cylindrical
    • A61F2002/30235Three-dimensional shapes cylindrical tubular, e.g. sleeves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30316The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
    • A61F2002/30535Special structural features of bone or joint prostheses not otherwise provided for
    • A61F2002/30593Special structural features of bone or joint prostheses not otherwise provided for hollow
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30667Features concerning an interaction with the environment or a particular use of the prosthesis
    • A61F2002/30677Means for introducing or releasing pharmaceutical products, e.g. antibiotics, into the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0063Three-dimensional shapes
    • A61F2230/0069Three-dimensional shapes cylindrical
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/252Polypeptides, proteins, e.g. glycoproteins, lipoproteins, cytokines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/412Tissue-regenerating or healing or proliferative agents
    • A61L2300/414Growth factors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/64Animal cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Transplantation (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Vascular Medicine (AREA)
  • Neurology (AREA)
  • Cardiology (AREA)
  • Dermatology (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Materials For Medical Uses (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Surgical Instruments (AREA)

Abstract

L'invention concerne des procédés, des instruments et des nécessaires de traitement de pseudarthrose vertébrale. Dans une réalisation, un procédé consiste à administrer à un emplacement de pseudarthrose vertébrale une quantité efficace d'une composition ostéo-inductrice comprenant une composition ostéo-inductrice sur un support acceptable sur le plan pharmaceutique. Dans d'autres réalisations, des forets à canule (10, 10', 10'') et des assemblages d'instruments chirurgicaux (50, 50') comprennent un foret et une seringue (60) et (60') dans lesquels la seringue possède une extrémité distale qui est engagée en conjonction avec une extrémité proximale du foret. Le foret et d'autres instruments, assemblages d'instruments, et des nécessaires qui en sont formés peuvent avantageusement être utilisés dans un procédé de traitement de pseudarthrose.
PCT/US2001/045479 2000-10-24 2001-10-24 Procedes et instruments destines au traitement de pseudarthrose WO2002034113A2 (fr)

Priority Applications (6)

Application Number Priority Date Filing Date Title
CA002426402A CA2426402A1 (fr) 2000-10-24 2001-10-24 Procedes et instruments destines au traitement de pseudarthrose
EP01988541A EP1335771A4 (fr) 2000-10-24 2001-10-24 Procedes et instruments destines au traitement de pseudarthrose
JP2002537173A JP2004512078A (ja) 2000-10-24 2001-10-24 偽関節症を治療する方法及び器具
AU2006902A AU2006902A (en) 2000-10-24 2001-10-24 Methods and instruments for treating pseudoarthrosis
US10/399,836 US8002775B2 (en) 2001-10-24 2001-10-24 Methods and instruments for treating pseudoarthrosis
AU2002220069A AU2002220069B2 (en) 2000-10-24 2001-10-24 Methods and instruments for treating pseudoarthrosis

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24295000P 2000-10-24 2000-10-24
US60/242,950 2000-10-24

Publications (2)

Publication Number Publication Date
WO2002034113A2 WO2002034113A2 (fr) 2002-05-02
WO2002034113A3 true WO2002034113A3 (fr) 2002-10-24

Family

ID=22916758

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/045479 WO2002034113A2 (fr) 2000-10-24 2001-10-24 Procedes et instruments destines au traitement de pseudarthrose

Country Status (5)

Country Link
EP (1) EP1335771A4 (fr)
JP (1) JP2004512078A (fr)
AU (2) AU2002220069B2 (fr)
CA (1) CA2426402A1 (fr)
WO (1) WO2002034113A2 (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020114795A1 (en) 2000-12-22 2002-08-22 Thorne Kevin J. Composition and process for bone growth and repair
US8002775B2 (en) 2001-10-24 2011-08-23 Warsaw Orthopedic, Inc. Methods and instruments for treating pseudoarthrosis
JP2005524710A (ja) * 2002-05-06 2005-08-18 ジェネンテック・インコーポレーテッド 骨欠陥の治療へのvegfの用途
FR2860422A1 (fr) * 2003-10-02 2005-04-08 Emmanuel Berque Dispositif d'application de substances adherentes biocompatible a clapet interne
WO2006102417A2 (fr) * 2005-03-22 2006-09-28 Warsaw Orthopedic, Inc. Mecanismes d'osteoinduction a l'aide d'une proteine de mineralisation lim-1 (lmp-1)
US7850656B2 (en) 2005-04-29 2010-12-14 Warsaw Orthopedic, Inc. Devices and methods for delivering medical agents
US8083722B2 (en) 2005-04-29 2011-12-27 Warsaw Orthopedic, Inc Instrumentation for injection of therapeutic fluid into joints
WO2010040076A2 (fr) * 2008-10-02 2010-04-08 Trans1, Inc. Procédé et appareil destinés à l’insertion de greffe osseuse
JP5272279B2 (ja) * 2010-03-09 2013-08-28 国立大学法人神戸大学 棘突起間インプラント
IT201900003947A1 (it) * 2019-03-19 2020-09-19 Mt Ortho S R L Granulo in materiale metallico biocompatibile per vertebroplastica.

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5824087A (en) * 1994-04-11 1998-10-20 Aberdeen University And Plasma Biotal Limited Bone regeneration
US6300127B1 (en) * 1997-07-30 2001-10-09 Emory University Bone mineralization proteins, DNA, vectors, expression systems

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4013080A (en) * 1974-10-03 1977-03-22 Froning Edward C Cannula connector and direction indicator means for injection system
JPS58155867A (ja) * 1982-03-12 1983-09-16 テルモ株式会社 穿刺針および穿刺針付医療用容器
US6241734B1 (en) * 1998-08-14 2001-06-05 Kyphon, Inc. Systems and methods for placing materials into bone
JP3424049B2 (ja) * 1994-03-09 2003-07-07 山之内製薬株式会社 骨形成用移植体
JP3125579B2 (ja) * 1994-05-24 2001-01-22 三菱マテリアル株式会社 生体用セメント充填装置
US5584839A (en) * 1994-12-12 1996-12-17 Gieringer; Robert E. Intraarticular drill guide and arthroscopic methods
US5676976A (en) * 1995-05-19 1997-10-14 Etex Corporation Synthesis of reactive amorphous calcium phosphates
US6039762A (en) * 1995-06-07 2000-03-21 Sdgi Holdings, Inc. Reinforced bone graft substitutes
US5779708A (en) * 1996-08-15 1998-07-14 Cyberdent, Inc. Intraosseous drug delivery device and method
AU742748B2 (en) * 1996-10-16 2002-01-10 Etex Corporation Method of preparing a poorly crystalline calcium phosphate and methods of its use
IL128261A0 (en) * 1999-01-27 1999-11-30 Disc O Tech Medical Tech Ltd Expandable element
JPH11313674A (ja) * 1998-04-30 1999-11-16 Hoechst Marion Roussel Kk ヒトbmp−4プロモーターおよびこれを用いた骨関連物質の探索法
AU3498300A (en) * 1999-02-22 2000-09-14 Peter A. Guagliano Method of treating an intervertebral disk

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5824087A (en) * 1994-04-11 1998-10-20 Aberdeen University And Plasma Biotal Limited Bone regeneration
US6300127B1 (en) * 1997-07-30 2001-10-09 Emory University Bone mineralization proteins, DNA, vectors, expression systems

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP1335771A4 *

Also Published As

Publication number Publication date
EP1335771A2 (fr) 2003-08-20
CA2426402A1 (fr) 2002-05-02
AU2006902A (en) 2002-05-06
JP2004512078A (ja) 2004-04-22
EP1335771A4 (fr) 2006-06-07
WO2002034113A2 (fr) 2002-05-02
AU2002220069B2 (en) 2005-12-15

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