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WO2002032944A3 - Basb208 nucleotide and amino acid sequences from haemophilus influenzae - Google Patents

Basb208 nucleotide and amino acid sequences from haemophilus influenzae Download PDF

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Publication number
WO2002032944A3
WO2002032944A3 PCT/EP2001/011557 EP0111557W WO0232944A3 WO 2002032944 A3 WO2002032944 A3 WO 2002032944A3 EP 0111557 W EP0111557 W EP 0111557W WO 0232944 A3 WO0232944 A3 WO 0232944A3
Authority
WO
WIPO (PCT)
Prior art keywords
basb208
haemophilus influenzae
nucleotide
amino acid
acid sequences
Prior art date
Application number
PCT/EP2001/011557
Other languages
French (fr)
Other versions
WO2002032944A2 (en
Inventor
Joelle Thonnard
Original Assignee
Smithkline Beecham Biolog
Joelle Thonnard
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Biolog, Joelle Thonnard filed Critical Smithkline Beecham Biolog
Priority to EP01983528A priority Critical patent/EP1326886A2/en
Priority to CA002425362A priority patent/CA2425362A1/en
Priority to AU2002215011A priority patent/AU2002215011A1/en
Publication of WO2002032944A2 publication Critical patent/WO2002032944A2/en
Publication of WO2002032944A3 publication Critical patent/WO2002032944A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
    • C07K16/1242—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Pasteurellaceae (F), e.g. Haemophilus influenza
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/285—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pasteurellaceae (F), e.g. Haemophilus influenza
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Communicable Diseases (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pulmonology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

BASB208 polypeptides from Haemophilus influenzae (and polynucleotides encoding BASB208 polypeptides) are disclosed. Methods for producing such polypeptides by recombinant techniques are also disclosed, as well as diagnostic, prophylactic and therapeutic uses of such polypeptides and polynucleotides.
PCT/EP2001/011557 2000-10-17 2001-10-05 Basb208 nucleotide and amino acid sequences from haemophilus influenzae WO2002032944A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP01983528A EP1326886A2 (en) 2000-10-17 2001-10-05 Basb208 nucleotide and amino acid sequences from haemophilus influenzae
CA002425362A CA2425362A1 (en) 2000-10-17 2001-10-05 Basb208 nucleotide and amino acid sequences from haemophilus influenzae
AU2002215011A AU2002215011A1 (en) 2000-10-17 2001-10-05 Basb208 nucleotide and amino acid sequences from haemophilus influenzae

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0025493.8 2000-10-17
GBGB0025493.8A GB0025493D0 (en) 2000-10-17 2000-10-17 Novel compounds

Publications (2)

Publication Number Publication Date
WO2002032944A2 WO2002032944A2 (en) 2002-04-25
WO2002032944A3 true WO2002032944A3 (en) 2002-11-14

Family

ID=9901505

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2001/011557 WO2002032944A2 (en) 2000-10-17 2001-10-05 Basb208 nucleotide and amino acid sequences from haemophilus influenzae

Country Status (5)

Country Link
EP (1) EP1326886A2 (en)
AU (1) AU2002215011A1 (en)
CA (1) CA2425362A1 (en)
GB (1) GB0025493D0 (en)
WO (1) WO2002032944A2 (en)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996033275A1 (en) * 1995-04-20 1996-10-24 Board Of Regents, The University Of Texas System H. INFLUENZAE HxuB AND HxuC GENES, PROTEINS AND METHODS OF USE
WO1999064067A2 (en) * 1998-06-11 1999-12-16 Smithkline Beecham Biologicals S.A. Vaccine
WO2000050599A1 (en) * 1999-02-24 2000-08-31 Smithkline Beecham Biologicals S.A. Haemophilus antigen

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996033275A1 (en) * 1995-04-20 1996-10-24 Board Of Regents, The University Of Texas System H. INFLUENZAE HxuB AND HxuC GENES, PROTEINS AND METHODS OF USE
WO1999064067A2 (en) * 1998-06-11 1999-12-16 Smithkline Beecham Biologicals S.A. Vaccine
WO2000050599A1 (en) * 1999-02-24 2000-08-31 Smithkline Beecham Biologicals S.A. Haemophilus antigen

Non-Patent Citations (10)

* Cited by examiner, † Cited by third party
Title
BAKALETZ L O ET AL: "Protection against development of otitis media induced by nontypeable Haemophilus influenzae by both active and passive immunization in a chinchilla model of virus-bacterium superinfection", INFECTION AND IMMUNITY, AMERICAN SOCIETY FOR MICROBIOLOGY. WASHINGTON, US, vol. 67, no. 6, June 1999 (1999-06-01), pages 2746 - 2762, XP002171132, ISSN: 0019-9567 *
BARENKAMP S J ET AL: "IDENTIFICATION OF A SECOND FAMILY OF HIGH MOLECULAR WEIGHT ADHESIONPROTEINS EXPRESSED BY NONTYPABLE HAEMOPHILUS INFLUENZAE (NTHI)", PEDIATRIC RESEARCH, WILLIAMS AND WILKINS, BALTIMORE, MD,, US, 7 May 1995 (1995-05-07), pages 170A, XP000579256, ISSN: 0031-3998 *
BARENKAMP S J: "CLONING AND EXPRESSION OF GENES FOR NONTYPABLE HAEMOPHILUS INFLUENZAE (NTHI) HIGH MOLECULAR WEIGHT (HMW) OUTER MEMBRANE PROTEINS WHICH ARE TARGETS OF BACTERICIDAL ANTIBODY", PEDIATRIC RESEARCH, WILLIAMS AND WILKINS, BALTIMORE, MD,, US, vol. 27, no. 4, 1990, pages 166A, XP000562288, ISSN: 0031-3998 *
BARENKAMP S J: "DNA SEQUENCE ANALYSIS OF GENES FOR NONTYPABLE HAEMOPHILUS INFLUENZAE (NTHI) HIGH MOLECULAR WEIGTH (HMW) OUTER MEMBRANE PROTEINS WHICH ARE TARGETS OF BACTERICIDAL ANTIBODY,", PEDIATRIC RESEARCH, WILLIAMS AND WILKINS, BALTIMORE, MD,, US, vol. 29, no. 4, 1991, pages 167A, XP000562287, ISSN: 0031-3998 *
BARENKAMP S J: "IMMUNIZATION WITH HIGH MOLECULAR WEIGHT (HMW) PROTEINS PROTECTS CHINCHILLAS AGAINST EXPERIMENTAL NONTYPABLE HAEMOPHILUS INFLUENZAE (NTHI) OTITIS MEDIA (OM)", PEDIATRIC RESEARCH, WILLIAMS AND WILKINS, BALTIMORE, MD,, US, vol. 33, no. 4, 1 April 1993 (1993-04-01), pages 162A, XP000561534, ISSN: 0031-3998 *
DATABASE EMBL [online] EMBL; 9 August 1995 (1995-08-09), XP002207129, retrieved from EBI Database accession no. HI32823 *
DATABASE SWISS-PROT [online] EMBL; 1 November 1997 (1997-11-01), XP002207128, retrieved from EBI Database accession no. Q57201 *
FLEISCHMANN ET AL, SCIENCE, vol. 269, 28 July 1995 (1995-07-28), pages 496 - 512, XP000517090 *
FLEISCHMANN ET AL: "Whole-Genome Random Sequencing and Assembly of Haemophilus influenzae Rd", SCIENCE, vol. 269, 28 July 1995 (1995-07-28), pages 496 - 512, XP000517090 *
LANGEN HANNO ET AL: "Two-dimensional map of the proteome of Haemophilus influenzae.", ELECTROPHORESIS., vol. 21, no. 2, January 2000 (2000-01-01), pages 411 - 429, XP001085261, ISSN: 0173-0835 *

Also Published As

Publication number Publication date
CA2425362A1 (en) 2002-04-25
WO2002032944A2 (en) 2002-04-25
GB0025493D0 (en) 2000-11-29
EP1326886A2 (en) 2003-07-16
AU2002215011A1 (en) 2002-04-29

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