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WO2002019995A3 - Pharmaceutical combination containing salmeterol and fluticasone - Google Patents

Pharmaceutical combination containing salmeterol and fluticasone Download PDF

Info

Publication number
WO2002019995A3
WO2002019995A3 PCT/GB2001/004001 GB0104001W WO0219995A3 WO 2002019995 A3 WO2002019995 A3 WO 2002019995A3 GB 0104001 W GB0104001 W GB 0104001W WO 0219995 A3 WO0219995 A3 WO 0219995A3
Authority
WO
WIPO (PCT)
Prior art keywords
fluticasone
pharmaceutical combination
combination containing
containing salmeterol
salmeterol
Prior art date
Application number
PCT/GB2001/004001
Other languages
French (fr)
Other versions
WO2002019995A2 (en
Inventor
Smithkline Glaxo
Original Assignee
Glaxo Group Ltd
Smithkline Glaxo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd, Smithkline Glaxo filed Critical Glaxo Group Ltd
Priority to AU2001284287A priority Critical patent/AU2001284287A1/en
Publication of WO2002019995A2 publication Critical patent/WO2002019995A2/en
Publication of WO2002019995A3 publication Critical patent/WO2002019995A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)

Abstract

The present invention relates to the use of salmeterol and fluticasone propionate combinations for the prophylaxis and treatment of rhinitis.
PCT/GB2001/004001 2000-09-07 2001-09-06 Pharmaceutical combination containing salmeterol and fluticasone WO2002019995A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2001284287A AU2001284287A1 (en) 2000-09-07 2001-09-06 Pharmaceutical combination containing salmeterol and fluticasone

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0021927.9A GB0021927D0 (en) 2000-09-07 2000-09-07 Use of pharmaceutical combination
GB0021927.9 2000-09-07

Publications (2)

Publication Number Publication Date
WO2002019995A2 WO2002019995A2 (en) 2002-03-14
WO2002019995A3 true WO2002019995A3 (en) 2002-08-22

Family

ID=9899002

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2001/004001 WO2002019995A2 (en) 2000-09-07 2001-09-06 Pharmaceutical combination containing salmeterol and fluticasone

Country Status (3)

Country Link
AU (1) AU2001284287A1 (en)
GB (1) GB0021927D0 (en)
WO (1) WO2002019995A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0124523D0 (en) * 2001-10-12 2001-12-05 Glaxo Group Ltd Pharmaceutical combination

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0416925A2 (en) * 1989-09-07 1991-03-13 Glaxo Group Limited Use of 4-hydroxy-alpha 1-[[[6-(4-phenylbutoxy)hexyl]amino]methyl]-1,3-benzenedimethanol or its salts in the treatment of allergy and inflammation
WO1997046243A1 (en) * 1996-06-04 1997-12-11 The Procter & Gamble Company A nasal spray containing an intranasal steroid and an antihistamine
WO1998017676A1 (en) * 1996-10-24 1998-04-30 Glaxo Group Limited A novel polymorphic crystalline form of fluticasone propionate, a method for its production and pharmaceutical compositions thereof
WO2001028535A2 (en) * 1999-10-21 2001-04-26 Glaxo Group Limited Pharmaceutical formulations comprising a combination of s-salmeterol and fluticasone propionate
WO2001047493A1 (en) * 1999-12-24 2001-07-05 Glaxo Group Limited Pharmaceutical aerosol formulation of salmeterol and fluticasone propionate

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0416925A2 (en) * 1989-09-07 1991-03-13 Glaxo Group Limited Use of 4-hydroxy-alpha 1-[[[6-(4-phenylbutoxy)hexyl]amino]methyl]-1,3-benzenedimethanol or its salts in the treatment of allergy and inflammation
WO1997046243A1 (en) * 1996-06-04 1997-12-11 The Procter & Gamble Company A nasal spray containing an intranasal steroid and an antihistamine
WO1998017676A1 (en) * 1996-10-24 1998-04-30 Glaxo Group Limited A novel polymorphic crystalline form of fluticasone propionate, a method for its production and pharmaceutical compositions thereof
WO2001028535A2 (en) * 1999-10-21 2001-04-26 Glaxo Group Limited Pharmaceutical formulations comprising a combination of s-salmeterol and fluticasone propionate
WO2001047493A1 (en) * 1999-12-24 2001-07-05 Glaxo Group Limited Pharmaceutical aerosol formulation of salmeterol and fluticasone propionate

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
BENINCASA C ET AL: "EVALUATION OF FLUTICASONE PROPIONATE AQUEOUS NASAL SPRAY TAKEN ALONE AND IN COMBINATION WITH CETIRIZINE IN THE PROPHYLACTIC TREATMENT OF SEASONAL ALLERGIC RHINITIS", DRUG INVESTIGATION, ADIS INTERNATIONAL, NZ, vol. 8, no. 4, 1994, pages 225 - 233, XP000651434, ISSN: 0114-2402 *
MANCINI V ET AL: "FLUTICASONE PROPIONATE OR BUDESONIDE WITH SALMETEROL IN BRONCHIAL SEVERE ASTHMA IN PEDIATRIC AGE", ALLERGY, MUNSKGAARD, COPENHAGEN, DK, vol. 53, no. SUPPL 43, 25 June 1998 (1998-06-25), pages 185, XP001013216, ISSN: 0105-4538 *
MARKHAM A ET AL: "INHALED SALMETEROL/FLUTICASONE PROPIONATE COMBINATION A REVIEW OF ITS USE IN PERSISTENT ASTHMA", DRUGS, ADIS INTERNATIONAL LTD, AT, vol. 60, no. 5, November 2000 (2000-11-01), pages 1207 - 1233, XP001013660, ISSN: 0012-6667 *
PALMQVIST M ET AL: "ONSET OF BRONCHODILATION OF BUDESONIDE/FORMOTEROL VS SALMETEROL/FLUTICASONE IN SINGLE INHALERS", PULMONARY PHARMACOLOGY AND THERAPEUTICS, ACADEMIC PRESS, NEW YORK, NY, US, vol. 14, no. 1, 2001, pages 29 - 34, XP001013120, ISSN: 1094-5539 *
PUHAKKA T ET AL: "Sinusitis in the common cold.", THE JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. UNITED STATES SEP 1998, vol. 102, no. 3, September 1998 (1998-09-01), pages 403 - 408, XP001079208, ISSN: 0091-6749 *
RATNER P H ET AL: "A comparison of the efficacy of fluticasone propionate aqueous nasal spray and loratadine, alone and in combination, for the treatment of seasonal allergic rhinitis", JOURNAL OF FAMILY PRACTICE, NEW YORK, NY, US, vol. 47, no. 2, August 1998 (1998-08-01), pages 118 - 125, XP002121956, ISSN: 0094-3509 *

Also Published As

Publication number Publication date
WO2002019995A2 (en) 2002-03-14
GB0021927D0 (en) 2000-10-25
AU2001284287A1 (en) 2002-03-22

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