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WO2002018581A3 - Recepteur couple aux proteines g - Google Patents

Recepteur couple aux proteines g Download PDF

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Publication number
WO2002018581A3
WO2002018581A3 PCT/US2001/027058 US0127058W WO0218581A3 WO 2002018581 A3 WO2002018581 A3 WO 2002018581A3 US 0127058 W US0127058 W US 0127058W WO 0218581 A3 WO0218581 A3 WO 0218581A3
Authority
WO
WIPO (PCT)
Prior art keywords
protein coupled
coupled receptors
gcrec
provides
polynucleotides
Prior art date
Application number
PCT/US2001/027058
Other languages
English (en)
Other versions
WO2002018581A9 (fr
WO2002018581A2 (fr
Inventor
Ernestine A Lee
Mariah R Baughn
Deborah A Kallick
Li Ding
Catherine M Tribouley
Chandra S Arvizu
Yalda Azimzai
Richard C Graul
Farrah A Khan
Danniel B Nguyen
Liam Kearney
Janice Au-Young
Original Assignee
Incyte Genomics Inc
Ernestine A Lee
Mariah R Baughn
Deborah A Kallick
Li Ding
Catherine M Tribouley
Chandra S Arvizu
Yalda Azimzai
Richard C Graul
Farrah A Khan
Danniel B Nguyen
Liam Kearney
Janice Au-Young
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Genomics Inc, Ernestine A Lee, Mariah R Baughn, Deborah A Kallick, Li Ding, Catherine M Tribouley, Chandra S Arvizu, Yalda Azimzai, Richard C Graul, Farrah A Khan, Danniel B Nguyen, Liam Kearney, Janice Au-Young filed Critical Incyte Genomics Inc
Priority to EP01966420A priority Critical patent/EP1366152A2/fr
Priority to JP2002522488A priority patent/JP2004520012A/ja
Priority to US10/363,481 priority patent/US20040038343A1/en
Priority to AU2001286935A priority patent/AU2001286935A1/en
Priority to CA002419342A priority patent/CA2419342A1/fr
Publication of WO2002018581A2 publication Critical patent/WO2002018581A2/fr
Publication of WO2002018581A9 publication Critical patent/WO2002018581A9/fr
Publication of WO2002018581A3 publication Critical patent/WO2002018581A3/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/04—Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Urology & Nephrology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Neurosurgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Physics & Mathematics (AREA)
  • Neurology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Pathology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)

Abstract

L'invention se rapporte à un récepteur couplé aux protéines G d'origine humaine (GCREC) et à des polynucléotides qui identifient et codent ces récepteurs GCREC. L'invention se rapporte également à des vecteurs d'expression, des cellules hôtes, des anticorps, des agonistes et des antagonistes. L'invention se rapporte également à des méthodes permettant de diagnostiquer, de traiter ou de prévenir des troubles associés à une expression aberrante de ces récepteurs GCREC.
PCT/US2001/027058 2000-08-31 2001-08-30 Recepteur couple aux proteines g WO2002018581A2 (fr)

Priority Applications (5)

Application Number Priority Date Filing Date Title
EP01966420A EP1366152A2 (fr) 2000-08-31 2001-08-30 Recepteur couple aux proteines g
JP2002522488A JP2004520012A (ja) 2000-08-31 2001-08-30 Ｇタンパク質共役受容体
US10/363,481 US20040038343A1 (en) 2001-08-30 2001-08-30 G-protein coupled receptors
AU2001286935A AU2001286935A1 (en) 2000-08-31 2001-08-30 G-protein coupled receptors
CA002419342A CA2419342A1 (fr) 2000-08-31 2001-08-30 Recepteur couple aux proteines g

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US22987100P 2000-08-31 2000-08-31
US60/229,871 2000-08-31
US23224300P 2000-09-13 2000-09-13
US60/232,243 2000-09-13
US24480600P 2000-10-31 2000-10-31
US60/244,806 2000-10-31

Publications (3)

Publication Number Publication Date
WO2002018581A2 WO2002018581A2 (fr) 2002-03-07
WO2002018581A9 WO2002018581A9 (fr) 2002-05-30
WO2002018581A3 true WO2002018581A3 (fr) 2003-07-10

Family

ID=27398018

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/027058 WO2002018581A2 (fr) 2000-08-31 2001-08-30 Recepteur couple aux proteines g

Country Status (5)

Country Link
EP (1) EP1366152A2 (fr)
JP (1) JP2004520012A (fr)
AU (1) AU2001286935A1 (fr)
CA (1) CA2419342A1 (fr)
WO (1) WO2002018581A2 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7803982B2 (en) 2001-04-20 2010-09-28 The Mount Sinai School Of Medicine Of New York University T1R3 transgenic animals, cells and related methods

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5891720A (en) * 1997-04-17 1999-04-06 Millennium Pharmaceuticals, Inc. Isolated DNA encoding a novel human G-protein coupled receptor
WO2000023588A2 (fr) * 1998-10-16 2000-04-27 Millennium Pharmaceuticals, Inc. Recepteurs couples a la proteine g
WO2001027158A2 (fr) * 1999-10-08 2001-04-19 Digiscents Sequences de recepteurs olfactifs

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5891720A (en) * 1997-04-17 1999-04-06 Millennium Pharmaceuticals, Inc. Isolated DNA encoding a novel human G-protein coupled receptor
WO2000023588A2 (fr) * 1998-10-16 2000-04-27 Millennium Pharmaceuticals, Inc. Recepteurs couples a la proteine g
WO2001027158A2 (fr) * 1999-10-08 2001-04-19 Digiscents Sequences de recepteurs olfactifs

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
BUERKI K: "CONCEPTS, POTENTIALS AND METHODS FOR CONSTRUCTING TRANSGENIC CELL AND ANIMALS", ARCHIVES OF TOXICOLOGY SUPPLEMENTS, SPRINGER VERLAG, DE, vol. 17, 1995, pages 3 - 7, XP000984880, ISSN: 0171-9750 *
DATABASE EMBL [online] 28 June 2000 (2000-06-28), "Homo sapiens genomic DNA, chromosome 1q22-q23, CD1 region, section 2/4", XP002220570, Database accession no. AP002533 *
DATABASE SWALL [online] 17 March 1992 (1992-03-17), "H.sapiens HGMP07J gene for olfactory receptor", XP002220571, Database accession no. X64995 *
PARMENTIER M ET AL: "EXPRESSION OF MEMBERS OF THE PUTATIVE OLFACTORY RECEPTOR GENE FAMILY IN MAMMALIAN GERM CELLS", NATURE, MACMILLAN JOURNALS LTD. LONDON, GB, vol. 355, X64995, 30 January 1992 (1992-01-30), pages 453 - 455, XP002029936, ISSN: 0028-0836 *

Also Published As

Publication number Publication date
JP2004520012A (ja) 2004-07-08
WO2002018581A9 (fr) 2002-05-30
WO2002018581A2 (fr) 2002-03-07
CA2419342A1 (fr) 2002-03-07
EP1366152A2 (fr) 2003-12-03
AU2001286935A1 (en) 2002-03-13

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