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WO2002016588A3 - 15985, a human serine/threonine protein kinase family membe r and uses thereof - Google Patents

15985, a human serine/threonine protein kinase family membe r and uses thereof Download PDF

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Publication number
WO2002016588A3
WO2002016588A3 PCT/US2001/026052 US0126052W WO0216588A3 WO 2002016588 A3 WO2002016588 A3 WO 2002016588A3 US 0126052 W US0126052 W US 0126052W WO 0216588 A3 WO0216588 A3 WO 0216588A3
Authority
WO
WIPO (PCT)
Prior art keywords
protein kinase
nucleic acid
kinase family
threonine protein
acid molecules
Prior art date
Application number
PCT/US2001/026052
Other languages
French (fr)
Other versions
WO2002016588A2 (en
Inventor
Rosana Kapeller-Libermann
Original Assignee
Millennium Pharm Inc
Rosana Kapeller-Libermann
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Millennium Pharm Inc, Rosana Kapeller-Libermann filed Critical Millennium Pharm Inc
Priority to AU2001286575A priority Critical patent/AU2001286575A1/en
Priority to EP01966031A priority patent/EP1320592A2/en
Publication of WO2002016588A2 publication Critical patent/WO2002016588A2/en
Priority to US10/170,789 priority patent/US7070947B2/en
Publication of WO2002016588A3 publication Critical patent/WO2002016588A3/en
Priority to US11/151,601 priority patent/US7198930B2/en
Priority to US11/636,948 priority patent/US7282360B2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)

Abstract

The invention provides isolated nucleic acids molecules, designated 15985 nucleic acid molecules, which encode novel serine/threonine protein kinase family members. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 15985 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a 15985 gene has been introduced or disrupted. The invention still further provides isolated 15985 proteins, fusion proteins, antigenic peptides and anti-15985 antibodies. Diagnostic methods utilizing compositions of the invention are also provided.
PCT/US2001/026052 2000-02-29 2001-08-21 15985, a human serine/threonine protein kinase family membe r and uses thereof WO2002016588A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
AU2001286575A AU2001286575A1 (en) 2000-08-21 2001-08-21 15985, a human serine/threonine protein kinase family member and uses thereof
EP01966031A EP1320592A2 (en) 2000-08-21 2001-08-21 "15985", a human serine/threonine protein kinase family member and uses thereof
US10/170,789 US7070947B2 (en) 2000-02-29 2002-06-13 Human protein kinase, phosphatase, and protease family members and uses thereof
US11/151,601 US7198930B2 (en) 2000-02-29 2005-06-13 Human protein kinase, phosphatase, and protease family members and uses thereof
US11/636,948 US7282360B2 (en) 2000-02-29 2006-12-11 Human protein kinase, phosphatase, and protease family members and uses thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US22674000P 2000-08-21 2000-08-21
US60/226,740 2000-08-21

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US10/170,789 Continuation-In-Part US7070947B2 (en) 2000-02-29 2002-06-13 Human protein kinase, phosphatase, and protease family members and uses thereof

Publications (2)

Publication Number Publication Date
WO2002016588A2 WO2002016588A2 (en) 2002-02-28
WO2002016588A3 true WO2002016588A3 (en) 2003-01-30

Family

ID=22850205

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/026052 WO2002016588A2 (en) 2000-02-29 2001-08-21 15985, a human serine/threonine protein kinase family membe r and uses thereof

Country Status (4)

Country Link
US (1) US20020192204A1 (en)
EP (1) EP1320592A2 (en)
AU (1) AU2001286575A1 (en)
WO (1) WO2002016588A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6476210B2 (en) * 2000-10-12 2002-11-05 Lexicon Genetics Incorporated Human kinases and polynucleotides encoding the same
US7198930B2 (en) * 2000-02-29 2007-04-03 Millennium Pharmaceuticals, Inc. Human protein kinase, phosphatase, and protease family members and uses thereof
US20040253669A1 (en) * 2001-08-22 2004-12-16 Yonghong Xiao Regulation of human dcamkl1-like serine/threonine protein kinase

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999015635A1 (en) * 1997-09-19 1999-04-01 Zeneca Limited Human ste20-like stress activated serine/threonine kinase
WO2000015770A2 (en) * 1998-09-16 2000-03-23 Incyte Pharmaceuticals, Inc. Human serine/threonine protein kinases
WO2000073469A2 (en) * 1999-05-28 2000-12-07 Sugen, Inc. Protein kinases
WO2002031129A2 (en) * 2000-10-12 2002-04-18 Lexicon Genetics Incorporated Human kinases and polynucleotides encoding the same

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999015635A1 (en) * 1997-09-19 1999-04-01 Zeneca Limited Human ste20-like stress activated serine/threonine kinase
WO2000015770A2 (en) * 1998-09-16 2000-03-23 Incyte Pharmaceuticals, Inc. Human serine/threonine protein kinases
WO2000073469A2 (en) * 1999-05-28 2000-12-07 Sugen, Inc. Protein kinases
WO2002031129A2 (en) * 2000-10-12 2002-04-18 Lexicon Genetics Incorporated Human kinases and polynucleotides encoding the same

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL [online] XP002209717, retrieved from EBI Database accession no. O15075 *
NAGASE T ET AL.: "PREDICTION OF THE CODING SEQUENCES OF UNIDENTIFIED HUMAN GENES VII. THE COMPLETE SEQUENCES OF 100 NEW CDNA CLONES FROM BRAIN WHICHCAN CODE FOR LARGE PROTEINS IN VITRO", DNA RESEARCH, UNIVERSAL ACADEMY PRESS, JP, vol. 4, 1997, pages 141 - 150, XP001052821 *

Also Published As

Publication number Publication date
AU2001286575A1 (en) 2002-03-04
WO2002016588A2 (en) 2002-02-28
EP1320592A2 (en) 2003-06-25
US20020192204A1 (en) 2002-12-19

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