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WO2002013967A3 - Mecanisme d'alignement de microreseaux - Google Patents

Mecanisme d'alignement de microreseaux Download PDF

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Publication number
WO2002013967A3
WO2002013967A3 PCT/US2001/024844 US0124844W WO0213967A3 WO 2002013967 A3 WO2002013967 A3 WO 2002013967A3 US 0124844 W US0124844 W US 0124844W WO 0213967 A3 WO0213967 A3 WO 0213967A3
Authority
WO
WIPO (PCT)
Prior art keywords
registration
workpiece
arm
roller
alignment mechanism
Prior art date
Application number
PCT/US2001/024844
Other languages
English (en)
Other versions
WO2002013967A2 (fr
Inventor
Eric J Rollins
Joeben Bevirt
Joshua N Guyot
Original Assignee
Incyte Genomics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Genomics Inc filed Critical Incyte Genomics Inc
Priority to AU2001281179A priority Critical patent/AU2001281179A1/en
Publication of WO2002013967A2 publication Critical patent/WO2002013967A2/fr
Publication of WO2002013967A3 publication Critical patent/WO2002013967A3/fr

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L9/00—Supporting devices; Holding devices
    • B01L9/52—Supports specially adapted for flat sample carriers, e.g. for plates, slides, chips
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/34—Microscope slides, e.g. mounting specimens on microscope slides
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00497—Features relating to the solid phase supports
    • B01J2219/00527—Sheets
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00497—Features relating to the solid phase supports
    • B01J2219/00527—Sheets
    • B01J2219/00533—Sheets essentially rectangular
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00596—Solid-phase processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00659—Two-dimensional arrays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00677—Ex-situ synthesis followed by deposition on the substrate
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/0068—Means for controlling the apparatus of the process
    • B01J2219/00686—Automatic
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/0068—Means for controlling the apparatus of the process
    • B01J2219/00686—Automatic
    • B01J2219/00689—Automatic using computers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/0068—Means for controlling the apparatus of the process
    • B01J2219/00686—Automatic
    • B01J2219/00691—Automatic using robots
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0822—Slides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00029—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
    • G01N2035/00099—Characterised by type of test elements
    • G01N2035/00158—Elements containing microarrays, i.e. "biochip"
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04—Details of the conveyor system
    • G01N2035/0474—Details of actuating means for conveyors or pipettes
    • G01N2035/0491—Position sensing, encoding; closed-loop control
    • G01N2035/0494—Detecting or compensating piositioning errors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Nanotechnology (AREA)
  • Optics & Photonics (AREA)
  • Clinical Laboratory Science (AREA)
  • Composite Materials (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • Materials Engineering (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Jigs For Machine Tools (AREA)
  • Specific Conveyance Elements (AREA)

Abstract

La présente invention concerne un mécanisme d'alignement permettant d'aligner une pièce à usiner telle qu'une microplaquette de microscope pour une machine de traitement de microréseaux. Le mécanisme d'alignement comprend une base de support fixe, un bras de commande et un élément de support à rouleaux. Le bras de commande est fixé de manière coulissante à la base de support et il comprend un actionneur et un bras de positionnement. Le bras de positionnement présente une première surface de positionnement et une seconde surface de positionnement. L'élément de support à rouleaux est également fixé de manière coulissante à la base de support et il comprend une portion de corps principale, un premier rouleau et un second rouleau. Le bras de commande peut faire coulisser le bras de positionnement et l'élément de support à rouleaux vers la pièce à usiner, de sorte que le premier rouleau presse le premier bord de la pièce à usiner contre la première surface de positionnement du bras de positionnement et le second rouleau presse le second bord de la pièce à usiner contre la seconde surface de positionnement du bras de positionnement. Afin d'aligner encore la pièce à usiner dans une troisième position, la pièce à usiner est pourvue d'une surface inférieure et le bras de positionnement présente une troisième surface de positionnement et une multitude de ressorts. La présente invention concerne un procédé intégré dans un dispositif de traitement de microréseaux permettant d'aligner une pièce à usiner.
PCT/US2001/024844 2000-08-11 2001-08-08 Mecanisme d'alignement de microreseaux WO2002013967A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2001281179A AU2001281179A1 (en) 2000-08-11 2001-08-08 Microarray alignment mechanism

Applications Claiming Priority (16)

Application Number Priority Date Filing Date Title
US22433800P 2000-08-11 2000-08-11
US22433700P 2000-08-11 2000-08-11
US22433500P 2000-08-11 2000-08-11
US22433600P 2000-08-11 2000-08-11
US60/224,338 2000-08-11
US60/224,337 2000-08-11
US60/224,335 2000-08-11
US60/224,336 2000-08-11
US63973300A 2000-08-15 2000-08-15
US63973200A 2000-08-15 2000-08-15
US63973400A 2000-08-15 2000-08-15
US63973100A 2000-08-15 2000-08-15
US09/639,734 2000-08-15
US09/638,733 2000-08-15
US09/639,731 2000-08-15
US09/639,732 2000-08-15

Publications (2)

Publication Number Publication Date
WO2002013967A2 WO2002013967A2 (fr) 2002-02-21
WO2002013967A3 true WO2002013967A3 (fr) 2002-08-08

Family

ID=27575221

Family Applications (4)

Application Number Title Priority Date Filing Date
PCT/US2001/024844 WO2002013967A2 (fr) 2000-08-11 2001-08-08 Mecanisme d'alignement de microreseaux
PCT/US2001/024850 WO2002014877A2 (fr) 2000-08-11 2001-08-08 Unite de recuperation de microreseaux
PCT/US2001/024994 WO2002014531A2 (fr) 2000-08-11 2001-08-09 Plateau a jeu ordonne de microdepots
PCT/US2001/024996 WO2002013968A2 (fr) 2000-08-11 2001-08-09 Unite de pose pour un jeu ordonne de microdepots

Family Applications After (3)

Application Number Title Priority Date Filing Date
PCT/US2001/024850 WO2002014877A2 (fr) 2000-08-11 2001-08-08 Unite de recuperation de microreseaux
PCT/US2001/024994 WO2002014531A2 (fr) 2000-08-11 2001-08-09 Plateau a jeu ordonne de microdepots
PCT/US2001/024996 WO2002013968A2 (fr) 2000-08-11 2001-08-09 Unite de pose pour un jeu ordonne de microdepots

Country Status (2)

Country Link
AU (4) AU2001281179A1 (fr)
WO (4) WO2002013967A2 (fr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6955788B2 (en) 2001-09-07 2005-10-18 Affymetrix, Inc. Apparatus and method for aligning microarray printing head
DE10261533A1 (de) * 2002-12-23 2004-07-15 BioChip Technologies GmbH Gesellschaft für Entwicklung und Produktion von Detektionssystemen Vorrichtung und Verfahren zum Halten von Objektträgern
JP2006126204A (ja) * 2004-10-29 2006-05-18 Affymetrix Inc ポリマーアレイを製造するための自動化方法
HUP0700404A2 (en) * 2007-06-08 2009-03-30 3D Histech Kft Catch frame for slide and slide feeding unit
US10509216B2 (en) 2012-12-26 2019-12-17 Ventana Medical Systems, Inc. Specimen processing systems and methods for aligning slides
US10746752B2 (en) 2009-11-13 2020-08-18 Ventana Medical Systems, Inc. Opposables and automated specimen processing systems with opposables
WO2014102184A2 (fr) * 2012-12-26 2014-07-03 Ventana Medical Systems, Inc. Systèmes de traitement d'échantillon et procédés d'alignement de lames porte-objets
CN102010817B (zh) * 2010-08-06 2013-05-22 博奥生物有限公司 一种微阵列芯片扫描仪的芯片自动装载装置
CN104053979B (zh) * 2011-11-16 2018-03-27 莱卡生物系统墨尔本私人有限公司 用于处理设置在基板上的生物样本的设备和自动方法
AU2012339620B2 (en) * 2011-11-16 2016-01-28 Leica Biosystems Melbourne Pty Ltd An automated system and method of treating tissue samples on slides
US9989448B2 (en) 2012-12-26 2018-06-05 Ventana Medical Systems, Inc. Specimen processing systems and methods for holding slides
US11274998B2 (en) 2012-12-26 2022-03-15 Ventana Medical Systems, Inc. Specimen processing systems and methods for holding slides
CN104007274B (zh) * 2014-06-04 2016-02-03 上海宏莘科技发展有限公司 夹脱型数码式全自动智能取样机
DE102016125691B4 (de) * 2016-12-23 2018-10-25 Leica Microsystems Cms Gmbh Halterung für einen Objektträger, Mikroskop und Verfahren zum Steuern eines Mikroskops
JP7126809B2 (ja) * 2017-04-13 2022-08-29 浜松ホトニクス株式会社 画像取得装置及び画像取得方法

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WO1992004651A1 (fr) * 1990-09-12 1992-03-19 Medical Research Council Pince pour lame porte-objet de microscope
US5592289A (en) * 1995-01-09 1997-01-07 Molecular Dynamics Self-aligning mechanism for positioning analyte receptacles
US5658802A (en) * 1995-09-07 1997-08-19 Microfab Technologies, Inc. Method and apparatus for making miniaturized diagnostic arrays
US5659421A (en) * 1995-07-05 1997-08-19 Neuromedical Systems, Inc. Slide positioning and holding device
DE19906422A1 (de) * 1998-11-20 2000-05-31 Leica Microsystems Halter für Objektträger

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Publication number Priority date Publication date Assignee Title
WO1992004651A1 (fr) * 1990-09-12 1992-03-19 Medical Research Council Pince pour lame porte-objet de microscope
US5592289A (en) * 1995-01-09 1997-01-07 Molecular Dynamics Self-aligning mechanism for positioning analyte receptacles
US5659421A (en) * 1995-07-05 1997-08-19 Neuromedical Systems, Inc. Slide positioning and holding device
US5658802A (en) * 1995-09-07 1997-08-19 Microfab Technologies, Inc. Method and apparatus for making miniaturized diagnostic arrays
DE19906422A1 (de) * 1998-11-20 2000-05-31 Leica Microsystems Halter für Objektträger

Also Published As

Publication number Publication date
AU2001281179A1 (en) 2002-02-25
WO2002013967A2 (fr) 2002-02-21
WO2002013968A3 (fr) 2003-01-16
AU2001281182A1 (en) 2002-02-25
WO2002013968A2 (fr) 2002-02-21
WO2002014877A2 (fr) 2002-02-21
WO2002014531A2 (fr) 2002-02-21
WO2002014877A3 (fr) 2003-01-03
AU2001279251A1 (en) 2002-02-25
WO2002014531A3 (fr) 2003-01-16
AU2001281217A1 (en) 2002-02-25

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