WO2002011613A2 - Aspiration d'echantillons - Google Patents
Aspiration d'echantillons Download PDFInfo
- Publication number
- WO2002011613A2 WO2002011613A2 PCT/GB2001/003535 GB0103535W WO0211613A2 WO 2002011613 A2 WO2002011613 A2 WO 2002011613A2 GB 0103535 W GB0103535 W GB 0103535W WO 0211613 A2 WO0211613 A2 WO 0211613A2
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- source
- valve
- chamber
- suction
- sample
- Prior art date
Links
- 239000012530 fluid Substances 0.000 title description 5
- 238000007789 sealing Methods 0.000 claims description 6
- 230000006835 compression Effects 0.000 claims description 5
- 238000007906 compression Methods 0.000 claims description 5
- 239000012528 membrane Substances 0.000 claims description 4
- 230000002380 cytological effect Effects 0.000 abstract description 4
- 230000003902 lesion Effects 0.000 description 4
- 238000003384 imaging method Methods 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 210000005224 forefinger Anatomy 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 210000003813 thumb Anatomy 0.000 description 2
- 230000001154 acute effect Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 230000001413 cellular effect Effects 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 230000006641 stabilisation Effects 0.000 description 1
- 230000008685 targeting Effects 0.000 description 1
- 210000003462 vein Anatomy 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
- A61B10/02—Instruments for taking cell samples or for biopsy
- A61B10/0233—Pointed or sharp biopsy instruments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/150007—Details
- A61B5/150015—Source of blood
- A61B5/15003—Source of blood for venous or arterial blood
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/150007—Details
- A61B5/150206—Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
- A61B5/150221—Valves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/150007—Details
- A61B5/150374—Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
- A61B5/150381—Design of piercing elements
- A61B5/150389—Hollow piercing elements, e.g. canulas, needles, for piercing the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/150007—Details
- A61B5/150374—Details of piercing elements or protective means for preventing accidental injuries by such piercing elements
- A61B5/150381—Design of piercing elements
- A61B5/150503—Single-ended needles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/153—Devices specially adapted for taking samples of venous or arterial blood, e.g. with syringes
- A61B5/154—Devices using pre-evacuated means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
- A61B10/02—Instruments for taking cell samples or for biopsy
- A61B10/0233—Pointed or sharp biopsy instruments
- A61B10/0283—Pointed or sharp biopsy instruments with vacuum aspiration, e.g. caused by retractable plunger or by connected syringe
Definitions
- the present invention relates to apparatus for the aspiration of samples
- Such samples are used for example in cytological examination.
- hypodermic needle Typically this is achieved by the use of a hypodermic needle and
- the technique requires medical staff to insert the needle at the correct location
- sample of cellular material is drawn up (aspirated) into the needle.
- the material can be any material that can be used to release and the needle withdrawn from the patient.
- the material can be any material that can be used to release the needle withdrawn from the patient.
- the target is usually either a visible or palpable mass or lesion seen
- US-A-2460641 describes a system in which a previously evacuated flask is
- the present invention seeks to enable the single handed operation of a device
- the present invention therefore provides apparatus comprising a sample receiving chamber connectable to a source of suction via a valve within the chamber, and an externally accessible operating mechanism linked to the valve thereby to permit selective connection between the chamber and the source.
- the source of suction is preferably a previously evacuated vessel. This will ideally have a wall section made of a penetrable membrane such as rubber.
- a cannula or other sharp tipped conduit will thus be able to gain access to the vacuum.
- the evacuated vessel could be integrated into the apparatus if desired.
- the valve preferably comprises a resilient member normally biased to rest in a sealing fashion against an outlet of the source of suction.
- the operating mechanism is preferably operable by squeezing the apparatus.
- a suitable mechanism is a compressible portion of the apparatus within which at least one substantially rigid rod members is attached at one end to the interior of the compressible portion and at the other to the valve and disposed at an angle to the compression direction. This arrangement results in the valve being displaced when the compressible portion is compressed.
- a preferred arrangement is one in which the apparatus is elongate with an annular thinned region thereabout to enable local compression.
- the valve can be located within the chamber to selectively seal a conduit leading to the chamber from the source of suction.
- Figure 1 is a cross section through the example of the invention prior to use
- Figure 2 is a cross section corresponding to figure 1 , showing the example in use;
- Figure 3 is a cross section on Ill-Ill of figure 1 ;
- Figure 4 shows the manner of expulsion of a sample from the example.
- figure 1 shows an apparatus 10 according to the invention which comprises an elongate barrel 1 2.
- the barrel has an open rear end 14 and a front end 1 6 which tapers to a conventional fitting 1 8 for a hypodermic needle 8, such as a Luer fitting.
- a disposable reservoir 20 is pre-evacuated and in the form of a cylinder sized to fit within the barrel.
- One end of the reservoir is sealed with a membrane 22 which extends across that end and attaches to the outer face of the cylinder.
- Sealing fins 24 extend outwardly to take up the tolerance between the outside of the reservoir and the inside of the barrel.
- an interior wall 26 divides the interior of the barrel into a sample region 28 and a reservoir-receiving region 30.
- the interior wall 26 is solid except for a central flow passage 32 extending into the reservoir-receiving region 30 and ending in a spike 34.
- a valve member 36 is located in the sample region 28 and has a tapered tip adapted to fit into the flow passage 32 in a sealing manner.
- the valve member 36 is held in place by a plurality of substantially rigid rod members 38 which are attached at another end to internal faces of the barrel. These rod members are shown in more detail in figure 3 and form spokes about the valve member 36 in order to support it without preventing fluid flow in its vicinity.
- the rod members are disposed within the barrel 1 2 at an acute angle to the radial dimension.
- the barrel wall is locally thinned in the region 40 where the rod members 38 are attached. This allows the barrel to be compressed in this region, deflecting the rod members due to the angle between them and the radial compression direction. This lifts the valve member 36 from the flow passage 32.
- FIG. 1 A hypodermic needle 8 is fitted onto the fitting 1 8.
- the reservoir is pushed home onto the spike 34, piercing the membrane 22.
- the valve member 36 prevents loss of the vacuum within the reservoir.
- the operator holds the apparatus as in the manner of a pencil, with thumb and forefinger lying gently on the locally thinned region 40, and the hypodermic is inserted into the appropriate area of the patient.
- the operator squeezes with thumb and forefinger, lifting the valve member from the passage 32 and allowing fluid communication between the reservoir 20 and the sample region 28.
- This evacuates the sample region 28 and a sample from the patient is drawn in the manner of US 2,460,641 .
- the pressure on the thinned region 40 is relaxed allowing the valve member to return to the a sealing position on the passage 32. Flow then stops and the hypodermic can be removed from the patient.
- the hypodermic 8 can (if desired) be removed, and the reservoir is removed and re-inserted in the barrel in a reversed orientation as shown in figure 4.
- the rear end of the reservoir is for this purpose formed with a sealing ring 42 about its outer edge to seal against the interior of the barrel 1 2, and a recess 44 adapted to accommodate the spike 34 when fully home.
- a suitably positioned receptacle can then be employed to collect the sample.
- the present invention permits the extraction of a sample from a patient with only single-handed operation at all material times.
- the reservoir could be replaced with a switchable source of vacuum or gas.
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Molecular Biology (AREA)
- Pathology (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Public Health (AREA)
- Surgery (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Manufacturing & Machinery (AREA)
- Sampling And Sample Adjustment (AREA)
Abstract
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2001276523A AU2001276523A1 (en) | 2000-08-08 | 2001-08-06 | Aspiration of samples |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0019466A GB2368286A (en) | 2000-08-08 | 2000-08-08 | Aspirating sample collection device |
GB0019466.2 | 2000-08-08 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2002011613A2 true WO2002011613A2 (fr) | 2002-02-14 |
WO2002011613A3 WO2002011613A3 (fr) | 2002-04-11 |
Family
ID=9897216
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/GB2001/003535 WO2002011613A2 (fr) | 2000-08-08 | 2001-08-06 | Aspiration d'echantillons |
Country Status (3)
Country | Link |
---|---|
AU (1) | AU2001276523A1 (fr) |
GB (1) | GB2368286A (fr) |
WO (1) | WO2002011613A2 (fr) |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2008020439A2 (fr) | 2006-08-17 | 2008-02-21 | Sialo Technology Israel Ltd | Manche microscopique optique intégral |
WO2014185904A1 (fr) * | 2013-05-15 | 2014-11-20 | Becton, Dickinson And Company | Régulateurs de pression à vide destinés a être utilisés pendant une collecte de sang |
CN109069133A (zh) * | 2016-01-28 | 2018-12-21 | 陶乐发展有限公司 | 活检注射器 |
CN109777725A (zh) * | 2019-02-25 | 2019-05-21 | 珠海迪尔生物工程有限公司 | 一种自动转种式血液培养仪 |
US10888262B2 (en) | 2013-05-15 | 2021-01-12 | Becton, Dickinson And Company | Vacuum pressure regulators for use during blood collection |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0608046D0 (en) | 2006-04-25 | 2006-05-31 | Star Syringe Ltd | Syringe |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3906930A (en) * | 1973-03-23 | 1975-09-23 | Dr Luis A Guerra | Blood taking device |
US3939822A (en) * | 1974-08-14 | 1976-02-24 | Jack Markowitz | Disposable blood collection and filtering device |
US4073288A (en) * | 1976-06-21 | 1978-02-14 | Chapman Samuel L | Blood sampling syringe |
US4166450A (en) * | 1977-07-22 | 1979-09-04 | Metatech Corporation | Device and procedure for collecting a succession of intravenous blood samples |
DE2750454C3 (de) * | 1977-11-11 | 1981-01-08 | Walter Sorstedt Kunststoff-Spritzgusswerk, 5223 Nuembrecht | Vorrichtung zur Blutentnahme |
US4215702A (en) * | 1978-01-12 | 1980-08-05 | Patrick Ayer | Arterial blood extraction device |
US4326541A (en) * | 1980-03-24 | 1982-04-27 | Arnold M. Heyman | Blood sample taking device |
US4340068A (en) * | 1980-06-18 | 1982-07-20 | Becton, Dickinson And Company | Multiple sample needle with vein entry indicator |
US5097842A (en) * | 1990-07-23 | 1992-03-24 | Bonn Gina B | Device for withdrawing fluids |
US5368029A (en) * | 1992-04-16 | 1994-11-29 | Holcombe; David A. | Integral catheter and blood tester |
IES980225A2 (en) * | 1998-03-25 | 1999-10-20 | Provost | A device for acquiring body samples for analysis |
-
2000
- 2000-08-08 GB GB0019466A patent/GB2368286A/en not_active Withdrawn
-
2001
- 2001-08-06 WO PCT/GB2001/003535 patent/WO2002011613A2/fr active Application Filing
- 2001-08-06 AU AU2001276523A patent/AU2001276523A1/en not_active Abandoned
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2008020439A2 (fr) | 2006-08-17 | 2008-02-21 | Sialo Technology Israel Ltd | Manche microscopique optique intégral |
WO2014185904A1 (fr) * | 2013-05-15 | 2014-11-20 | Becton, Dickinson And Company | Régulateurs de pression à vide destinés a être utilisés pendant une collecte de sang |
CN105307707A (zh) * | 2013-05-15 | 2016-02-03 | 贝克顿·迪金森公司 | 在血液采集期间使用的真空压力调节器 |
US10357192B2 (en) | 2013-05-15 | 2019-07-23 | Becton, Dickinson And Company | Vacuum pressure regulators for use during blood collection |
US10888262B2 (en) | 2013-05-15 | 2021-01-12 | Becton, Dickinson And Company | Vacuum pressure regulators for use during blood collection |
CN109069133A (zh) * | 2016-01-28 | 2018-12-21 | 陶乐发展有限公司 | 活检注射器 |
CN109777725A (zh) * | 2019-02-25 | 2019-05-21 | 珠海迪尔生物工程有限公司 | 一种自动转种式血液培养仪 |
CN109777725B (zh) * | 2019-02-25 | 2023-12-01 | 珠海迪尔生物工程股份有限公司 | 一种自动转种式血液培养仪 |
Also Published As
Publication number | Publication date |
---|---|
WO2002011613A3 (fr) | 2002-04-11 |
GB2368286A (en) | 2002-05-01 |
GB0019466D0 (en) | 2000-09-27 |
AU2001276523A1 (en) | 2002-02-18 |
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