WO2002008427A1 - A NOVEL POLYPEPTIDE- HUMAN Na+/K+ PUMP 9.57 AND THE POLYNUCLEOTIDE ENCODING SAID POLYPEPTIDE - Google Patents
A NOVEL POLYPEPTIDE- HUMAN Na+/K+ PUMP 9.57 AND THE POLYNUCLEOTIDE ENCODING SAID POLYPEPTIDE Download PDFInfo
- Publication number
- WO2002008427A1 WO2002008427A1 PCT/CN2001/001081 CN0101081W WO0208427A1 WO 2002008427 A1 WO2002008427 A1 WO 2002008427A1 CN 0101081 W CN0101081 W CN 0101081W WO 0208427 A1 WO0208427 A1 WO 0208427A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- polypeptide
- pump
- human
- polynucleotide encoding
- discloses
- Prior art date
Links
- 229920001184 polypeptide Polymers 0.000 title abstract 5
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 5
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 5
- 108091033319 polynucleotide Proteins 0.000 title abstract 3
- 102000040430 polynucleotide Human genes 0.000 title abstract 3
- 239000002157 polynucleotide Substances 0.000 title abstract 3
- 238000000034 method Methods 0.000 abstract 2
- 208000031886 HIV Infections Diseases 0.000 abstract 1
- 208000037357 HIV infectious disease Diseases 0.000 abstract 1
- 206010061218 Inflammation Diseases 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 108020004511 Recombinant DNA Proteins 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000033519 human immunodeficiency virus infectious disease Diseases 0.000 abstract 1
- 208000026278 immune system disease Diseases 0.000 abstract 1
- 230000004054 inflammatory process Effects 0.000 abstract 1
- 230000036210 malignancy Effects 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
The invention discloses a new polypeptide- human Na+/K+ pump 9.57, the polynucleotide encoding said polypeptide, and a process for producing the polypeptide by recombinant DNA technology. It also discloses methods of applying the polypeptide for the treatment of various diseases, such as malignancy, hemopathy, HIV infection, immune disorders, and inflammation. This invention also discloses antagonist against said polypeptide and thereof therapy uses. In addition, it refers to the use of said polynucleotide encoding this new human Na+/K+ pump 9.57.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2002210320A AU2002210320A1 (en) | 2000-06-30 | 2001-06-29 | A novel polypeptide- human na+/k+ pump 9.57 and the polynucleotide encoding saidpolypeptide |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 00116907 CN1331200A (en) | 2000-06-30 | 2000-06-30 | Polypeptide-human Na-K pump 9.57 and polynucleotide for coding it |
| CN00116907.6 | 2000-06-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| WO2002008427A1 true WO2002008427A1 (en) | 2002-01-31 |
Family
ID=4586306
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/CN2001/001081 WO2002008427A1 (en) | 2000-06-30 | 2001-06-29 | A NOVEL POLYPEPTIDE- HUMAN Na+/K+ PUMP 9.57 AND THE POLYNUCLEOTIDE ENCODING SAID POLYPEPTIDE |
Country Status (3)
| Country | Link |
|---|---|
| CN (1) | CN1331200A (en) |
| AU (1) | AU2002210320A1 (en) |
| WO (1) | WO2002008427A1 (en) |
-
2000
- 2000-06-30 CN CN 00116907 patent/CN1331200A/en active Pending
-
2001
- 2001-06-29 WO PCT/CN2001/001081 patent/WO2002008427A1/en active Application Filing
- 2001-06-29 AU AU2002210320A patent/AU2002210320A1/en not_active Abandoned
Non-Patent Citations (3)
| Title |
|---|
| DATABASE PROTEIN [online] 11 June 1999 (1999-06-11), SVERDLOV E.D. ET AL., retrieved from GI:88221 accession no. NCBI Database accession no. S00801 * |
| DATABASE PROTEIN [online] 13 September 1998 (1998-09-13), RUIZ A., BHAT S.P. AND BOK D., retrieved from GI:2136790 accession no. NCBI Database accession no. JC5108 * |
| DATABASE PROTEIN [online] 18 June 1999 (1999-06-18), KAWAKAMI K. ET AL., retrieved from GI:67976 accession no. NCBI Database accession no. PWHUNB * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1331200A (en) | 2002-01-16 |
| AU2002210320A1 (en) | 2002-02-05 |
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