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WO2002006479A3 - Apoptosis-inducing dna sequences - Google Patents

Apoptosis-inducing dna sequences Download PDF

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Publication number
WO2002006479A3
WO2002006479A3 PCT/EP2001/008170 EP0108170W WO0206479A3 WO 2002006479 A3 WO2002006479 A3 WO 2002006479A3 EP 0108170 W EP0108170 W EP 0108170W WO 0206479 A3 WO0206479 A3 WO 0206479A3
Authority
WO
WIPO (PCT)
Prior art keywords
apoptosis
dna sequences
inducing dna
relates
sequences
Prior art date
Application number
PCT/EP2001/008170
Other languages
German (de)
French (fr)
Other versions
WO2002006479A2 (en
Inventor
Stefan Grimm
Manuel Bauer
Nicole Schoenfeld
Erik Braziulis
Ursula Cramer
Andreas Gewies
Frank Voss
Thomas Mund
Timur Albayrak
Hendrik Gille
Matthias Klein
Original Assignee
Max Planck Gesellschaft
Stefan Grimm
Manuel Bauer
Nicole Schoenfeld
Erik Braziulis
Ursula Cramer
Andreas Gewies
Frank Voss
Thomas Mund
Timur Albayrak
Hendrik Gille
Matthias Klein
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE10126344A external-priority patent/DE10126344A1/en
Application filed by Max Planck Gesellschaft, Stefan Grimm, Manuel Bauer, Nicole Schoenfeld, Erik Braziulis, Ursula Cramer, Andreas Gewies, Frank Voss, Thomas Mund, Timur Albayrak, Hendrik Gille, Matthias Klein filed Critical Max Planck Gesellschaft
Priority to US10/332,859 priority Critical patent/US20040088746A1/en
Priority to EP01954041A priority patent/EP1349929A2/en
Priority to AU2001276406A priority patent/AU2001276406A1/en
Publication of WO2002006479A2 publication Critical patent/WO2002006479A2/en
Publication of WO2002006479A3 publication Critical patent/WO2002006479A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4747—Apoptosis related proteins
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)

Abstract

The invention relates to novel apoptosis-associated and especially apoptosis-inducing nucleic acid sequences, polypeptides which are coded by said sequences, and the use of the same for preparing diagnostic and therapeutic agents. The invention also relates to cell systems, transgenic animals and the use thereof for genetic and/or pharmacological research into apoptosis-associated illnesses.
PCT/EP2001/008170 2000-07-14 2001-07-13 Apoptosis-inducing dna sequences WO2002006479A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
US10/332,859 US20040088746A1 (en) 2000-07-14 2001-07-13 Apoptosis-inducing dna sequences
EP01954041A EP1349929A2 (en) 2000-07-14 2001-07-13 Apoptosis-inducing dna sequences
AU2001276406A AU2001276406A1 (en) 2000-07-14 2001-07-13 Apoptosis-inducing dna sequences

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE10034303 2000-07-14
DE10034303.1 2000-07-14
DE10126344.9 2001-05-30
DE10126344A DE10126344A1 (en) 2000-07-14 2001-05-30 Apoptosis-inducing DNA sequences

Publications (2)

Publication Number Publication Date
WO2002006479A2 WO2002006479A2 (en) 2002-01-24
WO2002006479A3 true WO2002006479A3 (en) 2003-07-17

Family

ID=26006388

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2001/008170 WO2002006479A2 (en) 2000-07-14 2001-07-13 Apoptosis-inducing dna sequences

Country Status (3)

Country Link
EP (1) EP1349929A2 (en)
AU (1) AU2001276406A1 (en)
WO (1) WO2002006479A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8486428B2 (en) 2006-03-27 2013-07-16 Board Of Regents, The University Of Texas System Compositions and methods for making and using acyclic N-halamine-based biocidal polymeric materials and articles
KR102637496B1 (en) 2013-03-13 2024-02-19 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 Stapled and stitched polypeptides and uses thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995015084A1 (en) * 1993-11-30 1995-06-08 Lxr Biotechnology Inc. Novel apoptosis-modulating proteins, dna encoding the proteins and methods of use thereof
WO2001012660A2 (en) * 1999-08-17 2001-02-22 Sagami Chemical Research Center HUMAN PROTEINS HAVING HYDROPHOBIC DOMAINS AND DNAs ENCODING THESE PROTEINS

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995015084A1 (en) * 1993-11-30 1995-06-08 Lxr Biotechnology Inc. Novel apoptosis-modulating proteins, dna encoding the proteins and methods of use thereof
WO2001012660A2 (en) * 1999-08-17 2001-02-22 Sagami Chemical Research Center HUMAN PROTEINS HAVING HYDROPHOBIC DOMAINS AND DNAs ENCODING THESE PROTEINS

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
BAUER MANUEL K A ET AL: "Adenine nucleotide translocase-1, a component of the permeability transition pore, can dominantly induce apoptosis.", JOURNAL OF CELL BIOLOGY, vol. 147, no. 7, 27 December 1999 (1999-12-27), pages 1493 - 1501, XP002210088, ISSN: 0021-9525 *
DATABASE EMBL [online] 12 December 1996 (1996-12-12), MARRA M. ET AL.: "mq28f04.r1 Barstead MPLRB1 Mus musculus cDNA clone IMAGE:580063 5', mRNA sequence", XP002210091, retrieved from EBI Database accession no. AA137662 *
DATABASE EMBL [online] 29 March 1997 (1997-03-29), MARRA M. ET AL.: "vc15d05.r1 Barstead MPLRB1 Mus musculus cDNA clone IMAGE:766569 5', mRNA sequence", XP002210089, retrieved from EBI Database accession no. AA273529 *
DATABASE EMBL [online] MARRA M. ET AL.: "uc81e12.y1 Sugano mouse kidney mkia Mus musculus cDNA clone IMAGE:1432078 5', mRNA sequence.", XP002210090, retrieved from EBI Database accession no. AA986577 *
GRIMM STEFAN ET AL: "An apoptosis-inducing isoform of neu differentiation factor (NDS) identified using a novel screen for dominant, apoptosis-inducing genes.", JOURNAL OF EXPERIMENTAL MEDICINE, vol. 185, no. 6, 1997, pages 1137 - 1142, XP000982878, ISSN: 0022-1007 *

Also Published As

Publication number Publication date
EP1349929A2 (en) 2003-10-08
WO2002006479A2 (en) 2002-01-24
AU2001276406A1 (en) 2002-01-30

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