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WO2002006465A3 - 7677, a novel human atpase family member and uses therefor - Google Patents

7677, a novel human atpase family member and uses therefor Download PDF

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Publication number
WO2002006465A3
WO2002006465A3 PCT/US2001/022165 US0122165W WO0206465A3 WO 2002006465 A3 WO2002006465 A3 WO 2002006465A3 US 0122165 W US0122165 W US 0122165W WO 0206465 A3 WO0206465 A3 WO 0206465A3
Authority
WO
WIPO (PCT)
Prior art keywords
nucleic acid
acid molecules
atpase family
family member
novel human
Prior art date
Application number
PCT/US2001/022165
Other languages
French (fr)
Other versions
WO2002006465A2 (en
WO2002006465A9 (en
Inventor
Rachel Meyers
Mark Williamson
Original Assignee
Millennium Pharm Inc
Rachel Meyers
Mark Williamson
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Millennium Pharm Inc, Rachel Meyers, Mark Williamson filed Critical Millennium Pharm Inc
Priority to AU2001275917A priority Critical patent/AU2001275917A1/en
Priority to EP01953472A priority patent/EP1299551A2/en
Publication of WO2002006465A2 publication Critical patent/WO2002006465A2/en
Publication of WO2002006465A9 publication Critical patent/WO2002006465A9/en
Publication of WO2002006465A3 publication Critical patent/WO2002006465A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

The invention provides isolated nucleic acids molecules, designated 7677 nucleic acid molecules, which encode novel ATPase family members. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 7677 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a 7677 gene has been introduced or disrupted. The invention still further provides isolated 7677 proteins, fusion proteins, antigenic peptides and anti-7677 antibodies. Diagnostic methods utilizing compositions of the invention are also provided.
PCT/US2001/022165 2000-07-13 2001-07-12 7677, a novel human atpase family member and uses therefor WO2002006465A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU2001275917A AU2001275917A1 (en) 2000-07-13 2001-07-12 7677, a novel human atpase family member and uses therefor
EP01953472A EP1299551A2 (en) 2000-07-13 2001-07-12 7677, a novel human atpase family member and uses therefor

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US21805300P 2000-07-13 2000-07-13
US60/218,053 2000-07-13
US71547900A 2000-11-17 2000-11-17
US09/715,479 2000-11-17

Publications (3)

Publication Number Publication Date
WO2002006465A2 WO2002006465A2 (en) 2002-01-24
WO2002006465A9 WO2002006465A9 (en) 2002-09-06
WO2002006465A3 true WO2002006465A3 (en) 2003-01-16

Family

ID=26912515

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/022165 WO2002006465A2 (en) 2000-07-13 2001-07-12 7677, a novel human atpase family member and uses therefor

Country Status (3)

Country Link
EP (1) EP1299551A2 (en)
AU (1) AU2001275917A1 (en)
WO (1) WO2002006465A2 (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999022007A1 (en) * 1997-10-28 1999-05-06 Shanghai Second Medical University Cbfaie10: a human skd1 gene
WO2001011089A1 (en) * 1999-08-05 2001-02-15 Agene Research Institute Co., Ltd. Novel method for screening compound for preventing or treating liver cell injury caused by hepatitis c virus and compound obtained by this method

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999022007A1 (en) * 1997-10-28 1999-05-06 Shanghai Second Medical University Cbfaie10: a human skd1 gene
WO2001011089A1 (en) * 1999-08-05 2001-02-15 Agene Research Institute Co., Ltd. Novel method for screening compound for preventing or treating liver cell injury caused by hepatitis c virus and compound obtained by this method

Non-Patent Citations (9)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL [online] 13 June 2001 (2001-06-13), Y. KAWABE ET AL: "Homo sapiens WHIP mRNA for Werner Helicase interacting protein , complete cds", XP002216583, retrieved from EBI,HINXTON, UK Database accession no. AB056152 *
DATABASE EMBL [online] 6 January 2000 (2000-01-06), NCI-CGAP: "xs46e12.x1 NCI_CGAP-Kid11 Homo sapiens cDNA clone IMAGE:2772718 3' similar to SW:YCAJ_HAEIN p45262 Hypothetical protein HI1590.; contains element TAR1 reptitive element; , mRNA sequence", XP002216582, retrieved from EBI, HINXTON, UK Database accession no. AW271333 *
DATABASE EMBL [online] 6 July 2000 (2000-07-06), A.W. ADAMSON ET AL: "Homo sapiens putative helicase RUVBL mRNA, complete Cds", XP002216580, retrieved from EBI, HINXTON,UK Database accession no. AF218313 *
DATABASE EMBL [online] 7 July 2000 (2000-07-07), NCI-CGAP: "hu11f02.x1 NCI_CGAP_lu24 Homo sapiens cDNA clone IMAGE:3166299 3' similar to SW:YCAJ_HAEIN P45262 Hypothetical protein HI1590.; contains element TAR1 repetitive element;, mRNA sequence", XP002216581, retrieved from EBI, HINXTON, UK Database accession no. BE222378 *
KAWABE YOH-ICHI ET AL: "A novel protein interacts with the Werner's syndrome gene product physically and functionally.", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 276, no. 23, AB056152, 8 June 2001 (2001-06-08), pages 20364 - 20369, XP002216578, ISSN: 0021-9258, Retrieved from the Internet <URL:EBI, HINXTON, UK> *
KAWABE YOH-ICHI ET AL: "Covalent modification of the Werner's syndrome gene product with the ubiquitin-related protein, SUMO-1.", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 275, no. 28, 14 July 2000 (2000-07-14), pages 20963 - 20966, XP002216579, ISSN: 0021-9258 *
See also references of EP1299551A2 *
UNPUBLISHED *
Y. KAWABE ET AL: "A novel protein interacts with the Werner 's syndrome gene product physically and functionally", JOURNAL OF BIOLOGICAL CHEMISTRY., vol. 276, no. 23, 8 June 2001 (2001-06-08), MD US, pages 20364 - 20369 *

Also Published As

Publication number Publication date
WO2002006465A2 (en) 2002-01-24
AU2001275917A1 (en) 2002-01-30
WO2002006465A9 (en) 2002-09-06
EP1299551A2 (en) 2003-04-09

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