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WO2002005641A1 - Composition antiparasitaire enrobee - Google Patents

Composition antiparasitaire enrobee Download PDF

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Publication number
WO2002005641A1
WO2002005641A1 PCT/EP2001/008009 EP0108009W WO0205641A1 WO 2002005641 A1 WO2002005641 A1 WO 2002005641A1 EP 0108009 W EP0108009 W EP 0108009W WO 0205641 A1 WO0205641 A1 WO 0205641A1
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WO
WIPO (PCT)
Prior art keywords
pesticide
active ingredient
releasing
granules
thermoplastic polymer
Prior art date
Application number
PCT/EP2001/008009
Other languages
English (en)
Inventor
Kenichi Kitagaki
Original Assignee
Syngenta Participations Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syngenta Participations Ag filed Critical Syngenta Participations Ag
Priority to JP2002511591A priority Critical patent/JP5016773B2/ja
Priority to AU2001287602A priority patent/AU2001287602A1/en
Publication of WO2002005641A1 publication Critical patent/WO2002005641A1/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/26—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests in coated particulate form

Definitions

  • the instant invention relates to a composition comprising a slow-releasing coated pesticide and a fast-releasing coated pesticide.
  • Coated solid pesticides are well known in the art, being usually applied for controlling the release of their active ingredients as described for example in PCT WO 99/01243.
  • conventional coated pesticides do not exhibit satisfactory release properties if the temperature varies, especially rises, after application thereof due to the temperature dependence of release rates of active ingredients.
  • a pesticidal composition comprising:
  • a slow-releasing coated solid pesticide comprising a pesticidal active ingredient which is formulated together with an inert carrier and a surfactant into granules or powder, which granules or powder are coated with a water-emulsifiable thermoplastic polymer and
  • a fast-releasing coated solid pesticide comprising the same active ingredient as that of the above pesticide (1 ) which is formulated together with an inert carrier and a surfactant into granules or powder, which granules or powder are coated with a water-emulsifiable thermoplastic polymer, characterized in that the slow-releasing and fast-releasing properties are controlled only by adjusting the contents of said thermoplastic polymer, only by adjusting the contents of said active ingredient, or by adjusting the contents of said thermoplastic polymer and contents of said active ingredient, unexpectedly exhibits desired release properties under varying, in particular rising temperature conditions, the temperature rising at least from 15°C to 25°C after application of said composition.
  • the above slow-releasing coated pesticide (1 ) usually exhibits long-lasting pesticidal effects at higher temperatures whilst the fast-releasing coated pesticide (2) usually shows long-lasting pesticidal effects at lower temperatures, in water. Therefore, by properly combining these two types of pesticides (1) and (2) with the same pesticidal active ingredient, it is possible to keep, in water, the release of the active ingredient substantially constant during the period where the temperature is initially low and finally high.
  • the composition of the instant invention as defined above achieves such controlled release even when it is applied only once at the initial stage of seeding / cultivation.
  • the pesticidal active ingredients to be used in the instant invention include herbicides, fungicides and insecticides as well as plant growth regulators and inhibitors and plant activators.
  • herbicides there are for example Pretilachlor, Clomeprop, Bifenox, Pyrazoxyfen, Pyrazolynate, Cinosulfuron, Dimepiperate, Bensulfuron-methyl, Pyrazosulfuron-ethyl, Naproanilide, Bromobutide, Mefenacet, Imazosulfuron, Daimuron, Bentazon, Simetryn, Etobenzanid, Cyhalofop-butyl, cafenstrole, Azimsulfuron, Pyriminobac-methyl, Benzofenap, Pyributicarb, Thenylchlor, MCPB, Benfuresate, Butamifos, Cyclosulfamuron, Dimethametryn, Esprocarb, Fentrazamide, Indanofan, Isoprothiolane, Molinate, Oxadiclomefon, Oxaziclomefone, Paclobutrazol, Pentoxazone, Prohexadi
  • fungicides there are for example Acibenzolar-S-Methyl, Isoprothiolane, Ipconazole, Iprodione, Oxolinic acid, Kasugamycin, Capropamid, Captan, Thiabendazole, Thiram, Thiophanate-methyl, Organocopper, Tricyclazole, Triflumizole, Validamycin, Azoxystrobin, Pyroquilon, Fludioxonil, Prochloraz, Probenazole, Benomyl, Methasulfocarb, TPN, BJL-002, BJL-003, Chlorothalonil, Copper, Diclocymet, Diclomezine, Edifenphos, Fenoxanil, Ferimzone, Flutolanil, Furametpyr, Hymexazol, Mepronil, Metominostrobin, Pefurazoate, Pencycuron, Tecloftalam and Thifluzamide.
  • Isoprothiolane As insecticides there are Isoprothiolane, Imidacloprid, Etofenprox, Cartap, Thiamethoxam, Thiocyclam, Bensultap, Bendiocarb, Monocrotophos, Alprocarb, Pymetrozine, Benfuracarb, Buprofezin, Carbosulfan, Cycloprothrin, Fenitrothion, Fipronil, Isoxathion, Phenthoate, Silafluofen, Triazophos, Trichlorfon, Methoxyfenozide and Clothianidin.
  • the solid carriers suitably used are normally natural mineral fillers, such as zeolite, calcite, talcum, kaolin, montmorillonite, attapulgite or other mineral carriers.
  • zeolite zeolite
  • calcite calcite
  • talcum kaolin
  • montmorillonite attapulgite or other mineral carriers.
  • highly dispersed silisic acid or highly dispersed absorbent polymers Suitable granulated adsorptive carriers are porous types, for example pumice, broken brick, sepiolite or bentonite, and suitable nonsorbent carriers are, for example, calcite or sand.
  • a great number of pregranulated materials of inorganic or organic nature can be used, e.g. especially dolomite or pulverised plant residues.
  • Suitable surfactants and dispersants are non-ionic, cationic and/or anionic having good emulsifying, dispersing and wetting properties.
  • Suitable anionic dispersants/surfactants are for example:
  • Salts of polystyrenesulfonic acid in particular the alkali metal, alkaline earth metal and ammonium salts;
  • Salts of polyvinylsulfonic acid in particular the alkali metal, alkaline earth metal and ammonium salts;
  • Salts of condensates of naphthalenesulfonic acids preferably naphthalene-2-sulfonic acid, with formaldehyde, in particular the alkali metal, alkaline earth metal and ammonium salts;
  • Salts of condensates of naphthalenesulfonic acid with phenolsulfonic acid and formaldehyde in particular the alkali metal, alkaline earth metal and ammonium salts;
  • Salts of ligninsulfonic acid in particular the sodium, potassium, magnesium, calcium or ammonium salts
  • Salts of naphthalenesulfonic acids in particular the alkali metal, alkaline earth metal and ammonium salts.
  • Suitable nonionic dispersants/surfactants are for example polyvinyl alcohol, polyvinyl methyl ether, polyvinylpyrrolidone, alkylated polyvinylpyrrolidone, hydroxyethyl cellulose, hydroxypropyl cellulose, methyl cellulose (degree of substitution: 1.5 to 2), hydroxyethylmethyl cellulose, hydroxypropylmethyl celulose, poly(2-hydroxyethyl)methacrylate, poly[2-(2-hydroxyethoxy)ethyl]methacrylate, polyethylene oxide (polyoxyethylene) and polyallyl alcohol (polyglycidol);
  • the number of ethylene oxide units or ethylene oxide and propylene oxide units is from 1 to 200, preferably from 5 to 100 and, most preferably, from 8 to 40.
  • Suitable cationic dispersants/surfactants are for example quaternary ammonium salts which contain, as N-substituent, at least one C 8 -C 22 alkyl radical and, as further substituents, unsaturated or halogenated lower alkyl, benzyl or hydroxy-lower alkyl radicals.
  • the granules or powders of pesticides of (1) and (2) can be produced by any known method, such as mixing the active ingredient with the carrier materials, dispersants /surfactants and adjuvants, subsequently granulation by means of extrusion, campaction, agglomeration by fluidized bed granulator or agitation granulator; milling by means of mechanical milling, e.g. hammer mill, or by means of wet milling, e.g. beads mill; tabletting by means of roller compactor.
  • the content of active ingredient can vary within a wide range, for example from 1-50wt% based on the total weight of the granules or powder.
  • Bion core GR2.5/2.7/2.8/3.3 which are granules containing Acibenzolar-S-Methyl in an amount of respectively 2.5, 2.7, 2.8 and 3.3wt%
  • Actara core GR2.4/2.5/3.3 which are granules containing Thiamethoxam in an amount of respectively 2.4, 2.5 and 3.3wt%
  • Pyroquilon core GR2.4/4.7/9.4/26.3 /32.2/36.6 which are granules containing Pyroquilon in an amount of respectively 2.4, 4.7, 9.4, 26.3, 32.2 and 36.6wt%, all of which are commercial products of Novartis Agro KK.
  • the above granules or powders Prior to coating with the water-emulsifiable thermoplastic polymer, the above granules or powders may be coated entirely or partially with a hydrophobic liquid, such as olive oil, palm oil, soybean oil, liquid paraffin or the like; preferably with liquid paraffin.
  • a hydrophobic liquid such as olive oil, palm oil, soybean oil, liquid paraffin or the like; preferably with liquid paraffin.
  • the hydrophobic liquid is used in an amount of 0.01-10wt%, preferably 0.05-5wt%, most preferably 0.1 -1wt%, based on the total weight of the composition of the instant invention.
  • Water-emulsifiable thermoplastic polymer accordinging to the instant invention means any polymer which is water-emulsifiable, thermoplastic and film forming. They are well known in the art.
  • polymers examples include polyethylene, polypropylene and copolymers of ethylene and/or propylene with unsubstituted or substituted olefins as comonomers; polyvinyl alcohol and copolymers of vinyl alcohol with unsubstituted or substituted olefins as comonomers; polymethacrylates, polyacrylates and copolymers of methacrylates and/or acrylates with unsubstituted or substituted olefins as comonomers; polymethacrylic acid, polyacrylic acid and polymaleic acid and copolymers of methacrylic acid, acrylic acid and/or maleic acid with unsubstituted or substituted olefins as comonomers; polymaleic acid esters and copolymers of maleic acid esters with unsubstituted or substituted olefins as comonomers; polyvinyl acetate and copolymers of vinyl acetate with unsubstitute
  • Preferred polymers are for example polyethylene, polypropylene and copolymers of ethylene and/or propylene with unsubstituted or substituted olefins as comonomers; polymethacrylates, polyacrylates and copolymers of methacrylates and/or acrylates with unsubstituted or substituted olefins as comonomers; polyvinylacetate and copolymers of vinylacetate with unsubstituted or substituted olefins as comonomers; polyacrylonitrile and copolymers of acrylonitrile with unsubstituted or substituted olefins as comonomers; copolymers of acrylamide or methacrylamide with unsubstituted or substituted olefins as comonomers; polybutadiene, polyisoprene, polychloroprene and copolymers of butadiene, isoprene, chloroprene or
  • Particularly preferred polymers are for example polyacrylates, such as polymethylacrylate and polyethylacrylate; polymethacrylates, such as polymethylmethacrylate and polyethylmethacrylate; polyvinylacetate; polystyrene; styrene/acrylate copolymers, such as styrene/methylacrylate and styrene/ethylacrylate; styrene/methacrylate copolymers, such as styrene/methylmethacrylate and styrene/ethylmethacrylate; vinylacetate/acrylate copolymers, such as vinylacetate/methylacrylate and vinylacetate/ethylacrylate; vinylacetate/methacrylate copolymers, such as vinylacetate/methylmethacrylate and vinylacetate/ethylmethacrylate; ethylene/vinylacetate copolymer; ethylene/vinylacetate/acrylate terpolymers, such as
  • the layers do not necessarily need to be made of identical polymer(s).
  • the first layer can be made of polyvinylacetate
  • the second layer from a polyethylene-polyvinylacetate mixture
  • the third layer from ethylene/vinylacetate/methylmethacrylate copolymer. If the layers are consisting of different polymers, an "inter-phase boundary" is formed between the layers which can be observed for example by using an optical microscope or an electron microscope.
  • the polymer content is 15-50wt%, preferably 20-40wt%, for pesticide (1 ) based on the total weight thereof, and 1-20wt%, preferably 2-15wt%, for pesticide (2) based on the total weight thereof.
  • the polymer contents may be determined empirically for each of pesticides (1 ) and (2) such that desired release property be obtained, said release property being strongly dependent on the nature and active ingredient content in the granules or powder of pesticides (1 ) and (2) as well as natural conditions under which the composition of the instant invention is applied.
  • the number of polymer coating layers varies with the thickness of each layer and can usually be 1-20, preferably 1-15.
  • the content of active ingredient can be chosen within a wide range, for example from 1-50wt% based on the total weight of the granules or powder.
  • the release control is to be achieved only by adjusting the contents of active ingredient, granules or powder with lower active ingredient content is used for pesticide (1) and those with higher active ingredient content for pesticide (2).
  • the active ingredient contents for pesticides (1) and (2) are empirically determined under a predetermined polymer content.
  • the number of polymer layers is 1-20, preferably 1-15.
  • the active ingredient contents of pesticides (1 ) and (2) are respectivelyl -50wt% based on the total weight of respective granules or powders, with the proviso that the former is lower than that of the latter.
  • the polymer content is 15-50wt%, preferably 20-40wt%, for pesticide (1) based on the total weight thereof and 1 -20wt%, preferably 2-15wt%, for pesticide (2) based on the total weight thereof.
  • the polymer contents may be determined empirically for each of pesticides (1) and (2) such that desired release property be obtained, said release property being strongly dependent on the nature and active ingredient content in the granules or powder of pesticides (1) and (2) as well as natural conditions under which the composition of the instant invention is applied.
  • the number of polymer coating layers varies with the thickness of each layer and can usually be 1-20, preferably 1-15.
  • the content of active ingredient can be chosen within a wide range, for example from 1 -50wt% based on the total weight of the granules or powder.
  • the active ingredient contents of pesticides (1) and (2) are respectively from 1-50wt% based on the total weight of respective granules or powders, where the former can be lower or higher than that of the latter. This combination enables the release control within an extraordinary wide range.
  • the granules or powders of pesticides (1) and (2) are preferably non-water-dispersible and may optionally be covered with other ingredients in order to avoid sticking together, for example by inorganic particles, such as talcum, clay, bentonite, calcium carbonate and the like, preferably by talcum.
  • inorganic particles such as talcum, clay, bentonite, calcium carbonate and the like, preferably by talcum.
  • Such ingredients may be added in an amount of 0.01 -10wt%, preferably 0.05-5wt%, most preferred 0.1-2wt%, based on the total weight of respective pesticides.
  • the pesticides (1) and/or (2) may additionally comprise other ingredients, such as fertilizers, binders, carrier materials and the like customarily used in the art.
  • composition of the instant invention may further comprise
  • (1 )' another slow-releasing coated solid pesticide comprising another pesticidal active ingredient (hereinafter, referred to as "another active ingredient”) which is formulated together with an inert carrier and a surfactant into granules or powder, which granules or powder are coated with a water-emulsifiable thermoplastic polymer and
  • (2)' another fast-releasing coated solid pesticide comprising "another active ingredient” which is formulated together with an inert carrier and a surfactant into granules or powder, which granules or powder are coated with a water-emulsifiable thermoplastic polymer, characterized in that the slow-releasing and fast-releasing properties are controlled only by adjusting the contents of said thermoplastic polymer, only by adjusting the contents of "another active ingredient", or by adjusting the contents of said thermoplastic polymer and contents of said "another active ingredient” .
  • Such a composition is particularly useful when desired to keep more than one pesticidal function, e.g. fungicidal function and insecticidal function, substantially constant under varying, in particular rising temperature conditions.
  • the invention further relates to a method for producing the composition as described above, comprising the steps of preparation of pesticides (1) and (2), followed by mixing them.
  • the process for the preparation of pesticide (1 ) comprises the step of:
  • steps 3-4 are carried out simultaneously and continuously.
  • Step 4 is advantageously carried out with pre-dried air kept at a temperature of 25-50°C.
  • a mixer used in step 1 any mixer known in the art, such as an onion pan, may be used. Particularly preferred is a concrete mixer customarily used in construction engineering.
  • the amount of the granules or powder to be charged into the mixer is determined in accordance with the capacity of the mixer as well as the required amount of pesticide (1).
  • Step 2 is an optional step. However, it is preferred to incorporate this step in view of prevention of the formation of agglomerates or flocculation of the granules or powder which eventually causes incomplete coating layers.
  • hydrophobic liquid such as olive oil, palm oil, and soybean oil can be used. Most preferred hydrophobic liquid is a liquid paraffin.
  • the hydrophobic liquid is added in an amount of 0.01 -10wt%, preferably 0.05-5wt%, more preferabny 0.1 -1wt%, based on the total weight of pesticide (1).
  • the aqueous polymer emulsion used in step 3 is prepared from water-emulsifiable thermoplastic polymers by mixing with water. The contact with dried air is usually achieved by means of air blow customarily used in the art. The blow rate can be selected in accordance with the amount of the granules or powder of step 1 and that of the aqueous polymer emulsion of step 2.
  • blow rate of 45 ⁇ VVmin is conveniently employed when the amount of granules (1 mm in diameter and 3 mm in length) of Step 1 is 200Kg and that of an aqueous PVAc (polyvinylacetate) emulsion (a 50% emulsion) of Step 2 is 11.9Kg.
  • Decrease in rate of drying can be detected by any known method, such as humidity detection.
  • Steps 3-4 are repeated until a set of coating layers is formed, which coating layers occupy the predetermined content in the granules or powder .
  • the number of coating layers is chosen in accordance with the above description.
  • rotation speed of 5-100rpm, preferably 5-50rpm, more preferably 5-30rpm is conveniently employed.
  • Step 4 or 5 other ingredients in order to avoid sticking together of the granules or powder may be added as described above.
  • the process for the preparation of pesticide (2) is similar to the above process for pesticide (1 ) except that the granules or powder in Step 1 have an active ingredient content different from that of pesticide (1 ) if the release control includes the adjustment of active ingredient content, that the kind of added polymer emulsion in Step 3 can be different although the polymer to be used for pesticide (2) is usually identical to that for pesticide (1 ), and that the number of coating layers in Step 5 is usually different from that of pesticide (1) if the release control includes the adjustment of polymer contents and every coating layer has the same thickness throughout pesticides (1 ) and (2).
  • the choice of the number of polymer layers and active ingredient content has already been described.
  • the pesticides (1) and (2) thus prepared are then mixed at a desired mixing ratio to thereby obtain a composition of the instant invention.
  • a composition comprising a first slow-releasing pesticide (1), a first fast-releasing pesticide (2), a second slow-releasing pesticide (1)' and a second fast-releasing pesticide (2)', where the active ingredient of (1)' and (2)' is different from that of (1) and (2)
  • the pesticides (1), (2), (1)' and (2)' can be separately prepared and then mixed at a desired mixing ratio.
  • this composition exhibits two different pesticidal functions corresponding to the active ingredients, which functions remain constant under rising temperature conditions.
  • Such a composition can also be prepared by subjecting a mixture of the granules or powders for pesticides (1 ) and (1)' to the above Steps 1-6 to thereby obtain a mixture of slow-releasing pesticides (1) and (1)' having the same polymer coating layers.
  • a mixture of fast-releasing pesticides (2) and (2)' is prepared in the same manner, followed by mixing with the above prepared mixture of the slow-releasing pesticides (1) and (1)'.
  • the mixing ratio between the granules for pesticides (1) and (1)' or (2) and (2)' corresponds to the desired mixing ratio of pesticides (1 ) and (1)' or (2) and (2)'.
  • Such a composition by firstly preparing granules or powder containing active ingredients for pesticides (1) and (1)', then subjecting to the above Steps 1-6 to obtain a mixture of slow-releasing pesticides (1) and (1)' only different in the kind and content of active ingredients.
  • a mixture of fast-releasing pesticides (2) and (2)' is prepared in the same manner, followed by mixing with the above prepared mixture of the slow-releasing pesticides (1) and (1 )'.
  • the mixing ratio between the active ingredients for pesticides (1) and (1)' or (2) and (2)' corresponds to the desired mixing ratio of pesticides (1 ) and (1)' or (2) and (2)'.
  • compositions of the instant invention are prepared and release behavior of some of them is examined.
  • Bion/Actara core GR (2.5+2.5):
  • Rod-like granules having a diameter of about 1mm and a length of about 3mm, consisting of
  • Neoraito Clay a product of NEORAITO KOSAN Co.,Ltd. Bion/Actara core GR (3.3+3.3):
  • Rod-like granules having a diameter of about 1 mm and length of about 3mm, consisting of
  • Rod-like granules having a diameter of about 1 mm and a length of about 3mm, consisting of
  • Rod-like granules having a diameter of about 1 mm and a length of about 3mm, consisting of
  • Rod-like granules having a diameter of about 1 mm and a length of about 3mm, consisting of
  • Rod-like granules having a diameter of about 1 mm and a length of about 3mm, consisting of
  • Rod-like granules having a diamter of about 1 mm and a length of about 3mm, consisting of
  • Rod-like granules having a diamter of about 1 mm and a length of about 3mm, consisting of
  • Rod-like granules having a diamter of about 1 mm and a length of about 3mm, consisting of 63.1 wt% of Pyroquilon,
  • SORPOL5115 (Alkenyl sulfonate) a product of TOHO CHEMICAL INDUSTRY CO., LTD., 5.0wt% of Amycol H (pregelatinized starch), a product of NIPPON STARCH CHEMICAL Co.,
  • Rod-like granules having a diamter of about 1 mm and a length of about 3mm, consisting of
  • Amycol H pregelatinized starch
  • Rod-like granules having a diamter of about 1 mm and a length of about 3mm, consisting of
  • SH-502 a PVAc 50% Emulsion, a product of Showa Kobunshi Co.
  • Moresco white P-70 a liquid paraffin, a product of Matsumura Oil Co.
  • Talcum TA talcum, a product of KUNIMINE INDUSTRIES Co., Ltd.
  • Bion/Actara core GR (2.5+2.5) 89.0wt%
  • Bion/Actara core GR (3.3+3.3) 66.0wt%
  • a composition is produced in the same manner as in Example 1 except that the mixture of fast-releasing coated pesticides and that of slow-releasing coated pesticides are mixed at a weight ratio of 6:4.
  • a composition is produced in the same manner as in Example 1 except that the mixture of fast-releasing coated pesticides and that of slow-releasing coated pesticides are mixed at a weight ratio of 4:6.
  • triply coated Pyroquilon/Actara core GR (2.4+2.4) is subjected to post drying under the conditions of 60°C in inlet air temperature and over 50°C in outlet air temperature.
  • step (10) is repeated four times.
  • step (10) is repeated four times.
  • step (10) is repeated four times.
  • the above prepared mixture of fast-releasing coated pesticides and solo of two slow-releasing coated pesticides are mixed at a weight ratio of 1 :1 :1 to thereby obtain a composition of the instant invention having two active ingredients.
  • the tip of the hole pipette When pipetting the liquid, the tip of the hole pipette is positioned at the medium point between the surface of the liquid and the bottom of the flask. After pipetting the liquid, 10ml of water having a German hardness of 3 degrees are added to the test system. If some granules are floating or flocculating in the liquid transferred to the centrifugation tube, it is centrifuged in order to sediment the granules.
  • Example 8 Experiments are carried out in the same manner as in Example 8 except that 250mg of the composition of step (13) of Example 1 is used instead of the pesticides prepared in step (6) or (12) of Example 1 or the pesticides prepared in step (6) or (17) of Example 4, that the release tests are carried out at 25°C and 15°C, that steps (2)-(3) of Example 7 are repeated 1 , 3, 7, 14, 28, 42, 56, 71 , 80 and 101 days after preparation of the test systems, and that only the concetrations of Thiamethoxam are determined.
  • Example 8 achieves constant release of active ingredient(s) under rising temperature conditions.
  • the fast-releasing pesticides of Example 4 (10% coat) complete the release of Pyroquilon in 14 days
  • the slow-releasing pesticides of the same Example (35% coating) only release 25% of Pyroquilon in 14 days at 25°C. If the temperature rises to a temperature higher than 25°C in 14 days, it is expected that the fast-releasing pesticides complete the release of Pyroquilon within a time shorter than 14 days before the temperature reaches the above temperature.
  • Example 9 is carried out in order to prove the above expectation using the composition of Example 1 , which composition is composed of the fast-releasing and slow-releasing pesticides where active ingredients are Acibenzolar-S-Methyl and Thiamethoxam.
  • Table 2 shows, the release rate of Thiamethoxam at 25°C is about twice as large as that at 15°C. However, the release rate during the first two weeks is about twice as larger as that during the third to fourth weeks both at 15°C and 25°C.
  • the release rate is 8% for the first week, 7% for the second week, 12% for the third week, 10% for the fourth and fifth weeks, 8.5% for the sixth and seventh weeks, and 8% for the eighth and ninth weeks.
  • the composition of the instant invention is also suited to applications where the release rate of active ingredient(s) need to be high at the initial stage but low and long-lasting afterwards.
  • the composition of the instant invention is an indispensible pesticidal composition for the current and future agriculture and horticulture where further reduction of labor of farmers is required.

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  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Agronomy & Crop Science (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

La présente invention concerne une composition antiparasitaire contenant: (1) un pesticide solide enrobé à libération lente, renfermant un ingrédient actif antiparasitaire formulé avec un support inerte et un tensioactif en granules ou en poudre, ces granules ou cette poudre étant enrobée d'un polymère thermoplastique émulsionnable dans l'eau, et (2) un pesticide solide enrobé à libération rapide, comportant le même ingrédient actif que dans le pesticide précité (1), formulé avec un support inerte et un tensioactif en granules ou en poudre, ces granules ou cette poudre étant enrobée d'un polymère thermoplastique émulsionnable dans l'eau. Cette invention est caractérisée en ce que les propriétés de libération lente et de libération rapide sont contrôlées uniquement par l'ajustement des proportions du polymère thermoplastique ou des proportions dudit ingrédient actif, ou alors par l'ajustement des proportions dudit polymère thermoplastique et celles dudit ingrédient actif. Cette composition permet d'obtenir les propriétés de libération voulues dans des conditions variables, particulièrement dans des températures croissantes.
PCT/EP2001/008009 2000-07-13 2001-07-11 Composition antiparasitaire enrobee WO2002005641A1 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2002511591A JP5016773B2 (ja) 2000-07-13 2001-07-11 被覆した有害生物殺滅剤組成物
AU2001287602A AU2001287602A1 (en) 2000-07-13 2001-07-11 Coated pesticidal composition

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0017277.5 2000-07-13
GBGB0017277.5A GB0017277D0 (en) 2000-07-13 2000-07-13 Organic compounds

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WO2002005641A1 true WO2002005641A1 (fr) 2002-01-24

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AU (1) AU2001287602A1 (fr)
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WO (1) WO2002005641A1 (fr)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1454528A1 (fr) * 2003-03-07 2004-09-08 Syngenta Participations AG Composition pesticide et procédé de préparation de pesticides solides enrobés
WO2007042185A2 (fr) * 2005-10-11 2007-04-19 Syngenta Participations Ag Methode de lutte contre les ravageurs et contre les champignons
WO2008151781A2 (fr) * 2007-06-14 2008-12-18 Syngenta Participations Ag Combinaisons pesticides
WO2011160982A1 (fr) * 2010-06-25 2011-12-29 Syngenta Participations Ag Procédés de lutte contre les acariens
EP2545775A2 (fr) 2005-09-29 2013-01-16 Everris International B.V. Compositions agrochimiques à libération contrôlée granulaire et son procédé de préparation
EP3020279A1 (fr) * 2014-11-11 2016-05-18 Lithos Industrial Minerals GmbH Particule de libération d'agents actifs
WO2023156946A1 (fr) * 2022-02-17 2023-08-24 Pi Industries Ltd. Granulés exempts de poussière et leur procédé de production

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6361063A (ja) * 1986-08-30 1988-03-17 Sumitomo Shoji Kk 塗料中に分散したマイクロカプセル殺虫製剤
EP0848906A1 (fr) * 1995-07-28 1998-06-24 Chisso Corporation Granules pesticides enrobes a usage agricole, procede de fabrication et mode d'emploi
EP0953282A1 (fr) * 1998-03-02 1999-11-03 Novartis AG Compositions pesticides
EP0966882A1 (fr) * 1997-01-20 1999-12-29 Chisso Corporation Granules agrochimiques non enrobes et granules agrochimiques enrobes a temps de liberation controle
WO2000007443A1 (fr) * 1998-08-05 2000-02-17 Basf Aktiengesellschaft Granulats pour le sol, a liberation controlee de la matiere active (cr)
EP1063215A2 (fr) * 1999-06-25 2000-12-27 LESCO, Inc. Briquettes à liberation controlée contenant des engrais et des pesticides

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH101405A (ja) * 1996-04-15 1998-01-06 Chisso Corp 被覆農薬粒剤混合物とその使用方法

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6361063A (ja) * 1986-08-30 1988-03-17 Sumitomo Shoji Kk 塗料中に分散したマイクロカプセル殺虫製剤
EP0848906A1 (fr) * 1995-07-28 1998-06-24 Chisso Corporation Granules pesticides enrobes a usage agricole, procede de fabrication et mode d'emploi
EP0966882A1 (fr) * 1997-01-20 1999-12-29 Chisso Corporation Granules agrochimiques non enrobes et granules agrochimiques enrobes a temps de liberation controle
EP0953282A1 (fr) * 1998-03-02 1999-11-03 Novartis AG Compositions pesticides
WO2000007443A1 (fr) * 1998-08-05 2000-02-17 Basf Aktiengesellschaft Granulats pour le sol, a liberation controlee de la matiere active (cr)
EP1063215A2 (fr) * 1999-06-25 2000-12-27 LESCO, Inc. Briquettes à liberation controlée contenant des engrais et des pesticides

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DATABASE WPI Week 198817, Derwent World Patents Index; AN 1988-115476, XP002182102 *
PATENT ABSTRACTS OF JAPAN vol. 012, no. 283 (C - 518) 3 August 1988 (1988-08-03) *

Cited By (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101155939B1 (ko) * 2003-03-07 2012-06-15 신젠타 파티서페이션즈 아게 농약 조성물, 및 피복된 고형 농약을 제조하는 방법
WO2004077947A1 (fr) * 2003-03-07 2004-09-16 Syngenta Participations Ag Composition pesticide et procede de production de pesticides solides enrobes
EP1454528A1 (fr) * 2003-03-07 2004-09-08 Syngenta Participations AG Composition pesticide et procédé de préparation de pesticides solides enrobés
US9012363B2 (en) 2005-09-29 2015-04-21 Everris International B.V. Granular controlled release agrochemical compositions and process for the preparation thereof
US8497229B2 (en) 2005-09-29 2013-07-30 Everris International B.V. Granular controlled release agrochemical compositions and process for the preparation thereof
EP2545775A2 (fr) 2005-09-29 2013-01-16 Everris International B.V. Compositions agrochimiques à libération contrôlée granulaire et son procédé de préparation
WO2007042185A2 (fr) * 2005-10-11 2007-04-19 Syngenta Participations Ag Methode de lutte contre les ravageurs et contre les champignons
WO2007042185A3 (fr) * 2005-10-11 2007-08-09 Syngenta Participations Ag Methode de lutte contre les ravageurs et contre les champignons
WO2008151781A2 (fr) * 2007-06-14 2008-12-18 Syngenta Participations Ag Combinaisons pesticides
CN101730472A (zh) * 2007-06-14 2010-06-09 先正达参股股份有限公司 包含杀虫剂和植物活化剂的农药组合
WO2008151781A3 (fr) * 2007-06-14 2009-02-26 Syngenta Participations Ag Combinaisons pesticides
WO2011160982A1 (fr) * 2010-06-25 2011-12-29 Syngenta Participations Ag Procédés de lutte contre les acariens
CN102958368A (zh) * 2010-06-25 2013-03-06 先正达参股股份有限公司 控制螨的方法
CN102958368B (zh) * 2010-06-25 2014-12-17 先正达参股股份有限公司 控制螨的方法
EP3020279A1 (fr) * 2014-11-11 2016-05-18 Lithos Industrial Minerals GmbH Particule de libération d'agents actifs
WO2016075205A1 (fr) * 2014-11-11 2016-05-19 Lithos Industrial Minerals Gmbh Particule à libération de principes actifs
US10624337B2 (en) 2014-11-11 2020-04-21 Lithos Crop Protect Gmbh Sustained release particles for controlling plant damaging organisms
EA037839B1 (ru) * 2014-11-11 2021-05-26 Литхос Кроп Протект Гмбх Частицы для высвобождения активных ингредиентов
WO2023156946A1 (fr) * 2022-02-17 2023-08-24 Pi Industries Ltd. Granulés exempts de poussière et leur procédé de production

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