+

WO2002096929A3 - Polypeptides réagissant avec les anticorps de patients infectés par le vhc et utilisations - Google Patents

Polypeptides réagissant avec les anticorps de patients infectés par le vhc et utilisations Download PDF

Info

Publication number
WO2002096929A3
WO2002096929A3 PCT/FR2002/001851 FR0201851W WO02096929A3 WO 2002096929 A3 WO2002096929 A3 WO 2002096929A3 FR 0201851 W FR0201851 W FR 0201851W WO 02096929 A3 WO02096929 A3 WO 02096929A3
Authority
WO
WIPO (PCT)
Prior art keywords
antibodies
hcv
seq
infected patients
reacting
Prior art date
Application number
PCT/FR2002/001851
Other languages
English (en)
Other versions
WO2002096929A2 (fr
Inventor
Reynaud Colette Jolivet
Original Assignee
Biomerieux Sa
Reynaud Colette Jolivet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biomerieux Sa, Reynaud Colette Jolivet filed Critical Biomerieux Sa
Priority to AU2002314283A priority Critical patent/AU2002314283A1/en
Publication of WO2002096929A2 publication Critical patent/WO2002096929A2/fr
Publication of WO2002096929A3 publication Critical patent/WO2002096929A3/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/576—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis
    • G01N33/5767—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis non-A, non-B hepatitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
    • C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Food Science & Technology (AREA)
  • Veterinary Medicine (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)

Abstract

L'invention concerne un polypeptide capable de réagir spécifiquement avec les anticorps de patients infectés par levirus VHC et dont la séquence peptidique comprend au moins une séquence choisie parmi SEQ ID NO: 2 ô SEQ ID NO: 17 et SEQ ID NO: 19 ô SEQ ID NO: 29, et leurs séquences équivalentes. L'invention concerne aussi l'utilisation de ce polypeptide pour la détection et la quantification d'anticorps anti-VHC ou de protéine Core, dans un échantillon biologique, et pour l'obtention d'anticorps.
PCT/FR2002/001851 2001-05-31 2002-05-31 Polypeptides réagissant avec les anticorps de patients infectés par le vhc et utilisations WO2002096929A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002314283A AU2002314283A1 (en) 2001-05-31 2002-05-31 Polypeptides reacting with hcv-infected patients' antibodies and uses

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR01/07184 2001-05-31
FR0107184A FR2825363A1 (fr) 2001-05-31 2001-05-31 Polypeptides reagissant avec les anticorps de patients infectes par vhc et utilisations

Publications (2)

Publication Number Publication Date
WO2002096929A2 WO2002096929A2 (fr) 2002-12-05
WO2002096929A3 true WO2002096929A3 (fr) 2003-12-24

Family

ID=8863850

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/FR2002/001851 WO2002096929A2 (fr) 2001-05-31 2002-05-31 Polypeptides réagissant avec les anticorps de patients infectés par le vhc et utilisations

Country Status (3)

Country Link
AU (1) AU2002314283A1 (fr)
FR (1) FR2825363A1 (fr)
WO (1) WO2002096929A2 (fr)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995012677A2 (fr) * 1993-11-04 1995-05-11 Innogenetics N.V. Epitopes de lymphocytes t humains immunodominants du virus de l'hepatite c
WO2000031130A1 (fr) * 1998-11-20 2000-06-02 Bio Merieux Polypeptides synthetiques correspondant au virus de l'hepatite c (hcv) et applications

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995012677A2 (fr) * 1993-11-04 1995-05-11 Innogenetics N.V. Epitopes de lymphocytes t humains immunodominants du virus de l'hepatite c
WO2000031130A1 (fr) * 1998-11-20 2000-06-02 Bio Merieux Polypeptides synthetiques correspondant au virus de l'hepatite c (hcv) et applications

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; March 2001 (2001-03-01), ZUCCHELLI SILVIA ET AL: "Mimotopes of the hepatitis C virus hypervariable region 1, but not the natural sequences, induce cross-reactive antibody response by genetic immunization.", XP002189145, Database accession no. PREV200100152812 *
HEPATOLOGY, vol. 33, no. 3, March 2001 (2001-03-01), pages 692 - 703, ISSN: 0270-9139 *
PUNTORIERO GIULIA ET AL: "Towards a solution for hepatitis C virus hypervariability: Mimotopes of the hypervariable region 1 can induce antibodies cross-reacting with a large number of viral variants.", EMBO (EUROPEAN MOLECULAR BIOLOGY ORGANIZATION) JOURNAL, vol. 17, no. 13, 1 July 1998 (1998-07-01), pages 3521 - 3533, XP002120168, ISSN: 0261-4189 *

Also Published As

Publication number Publication date
FR2825363A1 (fr) 2002-12-06
WO2002096929A2 (fr) 2002-12-05
AU2002314283A1 (en) 2002-12-09

Similar Documents

Publication Publication Date Title
EP2343318A3 (fr) Anticorps se liant à un fragment C-terminal de l'apolipoprotein E
CA2248140A1 (fr) Analyses et reactifs permettant de quantifier le hbnp
SE9500023D0 (sv) Method of detecting cancer
IL210455A0 (en) Novel cytokine zcytor17 ligand
WO2002018443A3 (fr) Anticorps monoclonal de recombinaison dirige contre les proteines contenant de la phosphotyrosine
EP2251356A3 (fr) Test ELISA polyclonal-monoclonal pour la détection de Pro-BNP N-terminal
EP0696640A3 (fr) Antigènes de recombinaison venant de la région NS3 du virus de l'hépatite C
AU2002223044A1 (en) Kit and method for detecting the esm-1 protein
EP1136547A3 (fr) Polypeptides Adamts, acides nucléiques codant pour ces polypeptides et leurs utilisations
WO2003027149A1 (fr) Anticorps et utilisation de ce dernier
WO2002097041A3 (fr) Proteines hybrides constituees de peptides et d'anticorps biologiquement actifs
CY1111763T1 (el) ΑΝΤΙΣΩΜΑΤΑ ΕΝΑΝΤΙΟΝ ΤΗΣ ΠΡΩΤΕΪΝΗΣ p51
EP0816504A3 (fr) Facteur d'activation des plaquettes acétylhydrolase, et gène codant celui-ci
WO1998008866B1 (fr) Bau, une proteine interactive associee a la sequence bin1, et utilisations
WO2002096929A3 (fr) Polypeptides réagissant avec les anticorps de patients infectés par le vhc et utilisations
WO2002102847A1 (fr) Nouveau ligand et son adn
FR2722508B1 (fr) Cassette d'expression d'une proteine p30 de toxoplasma gondii
EP1134286A3 (fr) Adamts polypeptides, acides nucléiques les codant et leurs applications
WO2001065262A3 (fr) Reactifs et methodes de detection des pathologies mammaires
WO2002038607A3 (fr) Recepteur
WO2002030977A3 (fr) Proteine a motif egf, materiaux egfl6 et procedes
JP2003532420A5 (fr)
WO2001042423A3 (fr) Compositions et procedes servant a detecter des proteines de stress
WO2002036633A3 (fr) Nouvelles proteines humaines 7tm et polynucleotides codant pour ces proteines
WO2001036587A3 (fr) Gene codant une proteine de surface de merozoite de plasmodium vivax

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ OM PH PL PT RO RU SD SE SG SI SK SL TJ TM TN TR TT TZ UA UG US UZ VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
121 Ep: the epo has been informed by wipo that ep was designated in this application
REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

122 Ep: pct application non-entry in european phase
NENP Non-entry into the national phase

Ref country code: JP

WWW Wipo information: withdrawn in national office

Country of ref document: JP

点击 这是indexloc提供的php浏览器服务，不要输入任何密码和下载