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WO2002092001A3 - Compositions and methods for the therapy and diagnosis of lung cancer - Google Patents

Compositions and methods for the therapy and diagnosis of lung cancer Download PDF

Info

Publication number
WO2002092001A3
WO2002092001A3 PCT/US2002/014975 US0214975W WO02092001A3 WO 2002092001 A3 WO2002092001 A3 WO 2002092001A3 US 0214975 W US0214975 W US 0214975W WO 02092001 A3 WO02092001 A3 WO 02092001A3
Authority
WO
WIPO (PCT)
Prior art keywords
compositions
diagnosis
lung cancer
therapy
polypeptides
Prior art date
Application number
PCT/US2002/014975
Other languages
French (fr)
Other versions
WO2002092001A2 (en
Inventor
Michael J Lodes
Tongtong Wang
Liqun Fan
Paul A Algate
Patricia D Mcneill
Heather Secrist
Darin R Benson
Robert A Henderson
Raodoh Mohamath
Original Assignee
Corixa Corp
Michael J Lodes
Tongtong Wang
Liqun Fan
Paul A Algate
Patricia D Mcneill
Heather Secrist
Darin R Benson
Robert A Henderson
Raodoh Mohamath
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/854,133 external-priority patent/US6759508B2/en
Application filed by Corixa Corp, Michael J Lodes, Tongtong Wang, Liqun Fan, Paul A Algate, Patricia D Mcneill, Heather Secrist, Darin R Benson, Robert A Henderson, Raodoh Mohamath filed Critical Corixa Corp
Priority to AU2002311909A priority Critical patent/AU2002311909A1/en
Priority to EP02739247A priority patent/EP1516049A4/en
Publication of WO2002092001A2 publication Critical patent/WO2002092001A2/en
Publication of WO2002092001A3 publication Critical patent/WO2002092001A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/30—Cellular immunotherapy characterised by the recombinant expression of specific molecules in the cells of the immune system
    • A61K40/32—T-cell receptors [TCR]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41—Vertebrate antigens
    • A61K40/42—Cancer antigens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57423—Specifically defined cancers of lung
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
    • A61K2239/46—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the cancer treated
    • A61K2239/55—Lung
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • Microbiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Compositions and methods for the therapy and diagnosis of cancer, particularly lung cancer, are disclosed. Illustrative compositions comprise one or more lung tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly lung cancer.
PCT/US2002/014975 2001-05-11 2002-05-10 Compositions and methods for the therapy and diagnosis of lung cancer WO2002092001A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU2002311909A AU2002311909A1 (en) 2001-05-11 2002-05-10 Compositions and methods for the therapy and diagnosis of lung cancer
EP02739247A EP1516049A4 (en) 2001-05-11 2002-05-10 COMPOSITIONS AND METHODS FOR THE THERAPY AND DIAGNOSIS OF LUNG CANCER

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/854,133 2001-05-11
US09/854,133 US6759508B2 (en) 2000-09-01 2001-05-11 Compositions and methods for the therapy and diagnosis of lung cancer

Publications (2)

Publication Number Publication Date
WO2002092001A2 WO2002092001A2 (en) 2002-11-21
WO2002092001A3 true WO2002092001A3 (en) 2005-01-13

Family

ID=25317820

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/014975 WO2002092001A2 (en) 2001-05-11 2002-05-10 Compositions and methods for the therapy and diagnosis of lung cancer

Country Status (3)

Country Link
EP (1) EP1516049A4 (en)
AU (1) AU2002311909A1 (en)
WO (1) WO2002092001A2 (en)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004016733A2 (en) 2002-08-16 2004-02-26 Agensys, Inc. Nucleic acid and corresponding protein entitled 251p5g2 useful in treatment and detection of cancer
US7226791B2 (en) * 2003-06-02 2007-06-05 Bristol-Myers Squibb Company Polynucleotides encoding novel guanylate binding proteins (GBP's)
MX337991B (en) 2008-08-05 2016-03-30 Toray Industries Cancer detection method.
AU2009278386B2 (en) 2008-08-05 2015-05-21 Toray Industries, Inc. Pharmaceutical composition for treatment and prevention of cancers
RU2603742C2 (en) 2010-02-04 2016-11-27 Торэй Индастриз, Инк. Pharmaceutical composition for treatment and/or prevention of cancer
BR112012018947B8 (en) 2010-02-04 2020-06-02 Toray Industries monoclonal anti-caprin-1 antibody, pharmaceutical composition, pharmaceutical combination and uses of a pharmaceutical composition, an antibody and a pharmaceutical combination
BR112012019098B8 (en) 2010-02-04 2021-08-17 Toray Industries antibody, pharmaceutical composition, pharmaceutical combination and uses of an antibody, a pharmaceutical composition and a pharmaceutical combination
JP5923985B2 (en) 2010-02-04 2016-05-25 東レ株式会社 Pharmaceutical composition for treatment and / or prevention of cancer
CN102844048A (en) 2010-02-04 2012-12-26 东丽株式会社 Pharmaceutical agent for treatment and/or prevention of cancer
AU2011211698B2 (en) 2010-02-04 2015-07-16 Toray Industries, Inc. Pharmaceutical composition for treating and/or preventing cancer
JP6094220B2 (en) 2011-08-04 2017-03-15 東レ株式会社 Method for detecting pancreatic cancer
US9181334B2 (en) 2011-08-04 2015-11-10 Toray Industries, Inc. Pharmaceutical composition for treatment and/or prophylaxis of cancer
DK2740795T3 (en) 2011-08-04 2017-01-16 Toray Industries Pharmaceutical composition for the treatment and / or prevention of cancer
CN103717739B (en) 2011-08-04 2015-07-29 东丽株式会社 Cancer treat and/or prevent pharmaceutical composition
US9180188B2 (en) 2011-08-04 2015-11-10 Toray Industries, Inc. Pharmaceutical composition for treatment and/or prophylaxis of cancer
PT2740489T (en) 2011-08-04 2017-01-10 Toray Industries Pharmaceutical composition for treatment and/or prevention of pancreatic cancer
HUE047006T2 (en) 2011-08-04 2020-04-28 Toray Industries Pharmaceutical composition comprising anti caprin-1 antibodies for treating and/or preventing cancer
JP6187256B2 (en) 2012-02-21 2017-08-30 東レ株式会社 Pharmaceutical composition for treatment and / or prevention of cancer
AU2013223137B2 (en) 2012-02-21 2017-10-19 Toray Industries, Inc. Pharmaceutical composition for treatment and/or prevention of cancer
US9266958B2 (en) 2012-02-21 2016-02-23 Toray Industries, Inc. Pharmaceutical composition for treatment and/or prevention of cancer
HUE044611T2 (en) 2012-02-21 2019-11-28 Toray Industries Pharmaceutical composition for treatment of cancer
BR112014023937A2 (en) 2012-03-30 2018-04-17 Toray Industries pharmaceutical composition, pharmaceutical combination and treatment method
BR112014024209A2 (en) 2012-03-30 2018-04-10 Toray Industries pharmaceutical composition, pharmaceutical agent and method of treating and / or preventing gallbladder cancer
CA2879304C (en) 2012-07-19 2020-07-14 Toray Industries, Inc. Method for detecting cancer
CN104471404B (en) 2012-07-19 2017-03-01 东丽株式会社 The detection method of cancer
RU2678138C2 (en) 2013-08-09 2019-01-23 Торэй Индастриз, Инк. Pharmaceutical composition for treatment and/or prevention of cancer

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5834248A (en) * 1995-02-10 1998-11-10 Millennium Pharmaceuticals Inc. Compositions and methods using rchd534, a gene uregulated by shear stress

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001000828A2 (en) * 1999-06-30 2001-01-04 Corixa Corporation Compositions and methods for the therapy and diagnosis of lung cancer
WO2001072295A2 (en) * 2000-03-29 2001-10-04 Corixa Corporation Compositions and methods for the therapy and diagnosis of lung cancer
CA2411278A1 (en) * 2000-06-09 2001-12-20 Corixa Corporation Compositions and methods for the therapy and diagnosis of colon cancer

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5834248A (en) * 1995-02-10 1998-11-10 Millennium Pharmaceuticals Inc. Compositions and methods using rchd534, a gene uregulated by shear stress

Also Published As

Publication number Publication date
EP1516049A2 (en) 2005-03-23
EP1516049A4 (en) 2006-01-11
AU2002311909A1 (en) 2002-11-25
WO2002092001A2 (en) 2002-11-21

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