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WO2002083293A3 - Banques chimiques fondees sur des particules codees - Google Patents

Banques chimiques fondees sur des particules codees Download PDF

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Publication number
WO2002083293A3
WO2002083293A3 PCT/GB2002/001790 GB0201790W WO02083293A3 WO 2002083293 A3 WO2002083293 A3 WO 2002083293A3 GB 0201790 W GB0201790 W GB 0201790W WO 02083293 A3 WO02083293 A3 WO 02083293A3
Authority
WO
WIPO (PCT)
Prior art keywords
chemical libraries
libraries based
coded particles
library
zone
Prior art date
Application number
PCT/GB2002/001790
Other languages
English (en)
Other versions
WO2002083293A2 (fr
Inventor
Susan Louise Watson
Amit Kumar Som
Nigel Guy Skinner
Original Assignee
3 D Molecular Sciences Ltd
Susan Louise Watson
Amit Kumar Som
Nigel Guy Skinner
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 3 D Molecular Sciences Ltd, Susan Louise Watson, Amit Kumar Som, Nigel Guy Skinner filed Critical 3 D Molecular Sciences Ltd
Publication of WO2002083293A2 publication Critical patent/WO2002083293A2/fr
Publication of WO2002083293A3 publication Critical patent/WO2002083293A3/fr

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Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0046Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/00497Features relating to the solid phase supports
    • B01J2219/005Beads
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/00497Features relating to the solid phase supports
    • B01J2219/00502Particles of irregular geometry
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/0054Means for coding or tagging the apparatus or the reagents
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/0054Means for coding or tagging the apparatus or the reagents
    • B01J2219/00545Colours
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/0054Means for coding or tagging the apparatus or the reagents
    • B01J2219/00547Bar codes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/0054Means for coding or tagging the apparatus or the reagents
    • B01J2219/00554Physical means
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277Apparatus
    • B01J2219/0054Means for coding or tagging the apparatus or the reagents
    • B01J2219/00554Physical means
    • B01J2219/0056Raised or sunken areas
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583Features relative to the processes being carried out
    • B01J2219/00585Parallel processes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583Features relative to the processes being carried out
    • B01J2219/00596Solid-phase processes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/0068Means for controlling the apparatus of the process
    • B01J2219/00686Automatic
    • B01J2219/00689Automatic using computers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718Type of compounds synthesised
    • B01J2219/0072Organic compounds
    • B01J2219/00722Nucleotides
    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00Libraries per se, e.g. arrays, mixtures
    • C40B40/04Libraries containing only organic compounds
    • C40B40/06Libraries containing nucleotides or polynucleotides, or derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B70/00Tags or labels specially adapted for combinatorial chemistry or libraries, e.g. fluorescent tags or bar codes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

La présente invention concerne une banque chimique et un procédé de création de cette banque, qui comprend des particules ayant chacune au moins une première zone et une deuxième zone, chaque zone comportant en surface un élément chimique respectif de ladite banque, chaque particule comprenant des marques servant à identifier la particule et à identifier lesdites zones de la particule et servant ainsi à identifier l'élément chimique de la banque sur n'importe quelle zone sélectionnée.
PCT/GB2002/001790 2001-04-18 2002-04-18 Banques chimiques fondees sur des particules codees WO2002083293A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0109746.8 2001-04-18
GB0109746A GB0109746D0 (en) 2001-04-18 2001-04-18 Chemical libraries based on coded particles

Publications (2)

Publication Number Publication Date
WO2002083293A2 WO2002083293A2 (fr) 2002-10-24
WO2002083293A3 true WO2002083293A3 (fr) 2003-01-09

Family

ID=9913155

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2002/001790 WO2002083293A2 (fr) 2001-04-18 2002-04-18 Banques chimiques fondees sur des particules codees

Country Status (2)

Country Link
GB (1) GB0109746D0 (fr)
WO (1) WO2002083293A2 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0111470D0 (en) * 2001-05-10 2001-07-04 Scient Generics Ltd Homogenous photoresist functionalisation

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2306484A (en) * 1995-10-26 1997-05-07 Univ Hertfordshire Solid support particle marked with a machine-readable code for use in Combinatorial Chemistry Techniques
WO1997019958A1 (fr) * 1995-11-30 1997-06-05 Wlodek Mandecki Criblage des drogues a partir de bibliotheques chimiques combinatoires au moyen de transpondeurs
GB2334347A (en) * 1998-02-13 1999-08-18 Univ Hertfordshire Method of fabricating coded particles
WO2000073504A2 (fr) * 1999-06-01 2000-12-07 Hitachi Software Engineering Co., Ltd. Puce a microreseau et son procede d'indexation
WO2001025002A1 (fr) * 1999-10-01 2001-04-12 Surromed,Inc. Particules de tige colloidales servant de codes nanobar
WO2001051207A1 (fr) * 2000-01-10 2001-07-19 Genospectra, Inc. Support de sondes lineaire

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2306484A (en) * 1995-10-26 1997-05-07 Univ Hertfordshire Solid support particle marked with a machine-readable code for use in Combinatorial Chemistry Techniques
WO1997019958A1 (fr) * 1995-11-30 1997-06-05 Wlodek Mandecki Criblage des drogues a partir de bibliotheques chimiques combinatoires au moyen de transpondeurs
GB2334347A (en) * 1998-02-13 1999-08-18 Univ Hertfordshire Method of fabricating coded particles
WO2000073504A2 (fr) * 1999-06-01 2000-12-07 Hitachi Software Engineering Co., Ltd. Puce a microreseau et son procede d'indexation
WO2001025002A1 (fr) * 1999-10-01 2001-04-12 Surromed,Inc. Particules de tige colloidales servant de codes nanobar
WO2001051207A1 (fr) * 2000-01-10 2001-07-19 Genospectra, Inc. Support de sondes lineaire

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
XIAO-YI XIAO ET AL.: "COMBINATORIAL CHEMISTRY WITH LASER OPTICAL ENCODING", ANGEWANDTE CHEMIE. INTERNATIONAL EDITION, VERLAG CHEMIE, vol. 36, no. 7, 1997, WEINHEIM, DE, pages 780 - 782, XP000198595, ISSN: 0570-0833 *

Also Published As

Publication number Publication date
GB0109746D0 (en) 2001-06-13
WO2002083293A2 (fr) 2002-10-24

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