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WO2002063004A3 - G-protein coupled receptors - Google Patents

G-protein coupled receptors Download PDF

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Publication number
WO2002063004A3
WO2002063004A3 PCT/US2002/003635 US0203635W WO02063004A3 WO 2002063004 A3 WO2002063004 A3 WO 2002063004A3 US 0203635 W US0203635 W US 0203635W WO 02063004 A3 WO02063004 A3 WO 02063004A3
Authority
WO
WIPO (PCT)
Prior art keywords
protein coupled
coupled receptors
gcrec
provides
polynucleotides
Prior art date
Application number
PCT/US2002/003635
Other languages
French (fr)
Other versions
WO2002063004A2 (en
Inventor
Mariah R Baughn
Catherine M Tribouley
Danniel B Nguyen
Michael Thornton
Original Assignee
Incyte Genomics Inc
Mariah R Baughn
Catherine M Tribouley
Danniel B Nguyen
Michael Thornton
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Genomics Inc, Mariah R Baughn, Catherine M Tribouley, Danniel B Nguyen, Michael Thornton filed Critical Incyte Genomics Inc
Priority to EP02718924A priority Critical patent/EP1366165A2/en
Priority to CA002437717A priority patent/CA2437717A1/en
Priority to JP2002562741A priority patent/JP2005503111A/en
Priority to US10/467,252 priority patent/US20040115676A1/en
Publication of WO2002063004A2 publication Critical patent/WO2002063004A2/en
Publication of WO2002063004A3 publication Critical patent/WO2002063004A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C07K14/723—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH receptor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Neurology (AREA)
  • Virology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Endocrinology (AREA)
  • Peptides Or Proteins (AREA)

Abstract

The invention provides human G-protein coupled receptors (GCREC) and polynucleotides which identify and encode GCREC. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of GCREC.
PCT/US2002/003635 2001-02-07 2002-02-06 G-protein coupled receptors WO2002063004A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
EP02718924A EP1366165A2 (en) 2001-02-07 2002-02-06 G-protein coupled receptors
CA002437717A CA2437717A1 (en) 2001-02-07 2002-02-06 G-protein coupled receptors
JP2002562741A JP2005503111A (en) 2001-02-07 2002-02-06 G protein coupled receptor
US10/467,252 US20040115676A1 (en) 2002-02-06 2002-02-06 G-protein coupled receptors

Applications Claiming Priority (14)

Application Number Priority Date Filing Date Title
US26732201P 2001-02-07 2001-02-07
US60/267,322 2001-02-07
US27121501P 2001-02-23 2001-02-23
US60/271,215 2001-02-23
US27455101P 2001-03-08 2001-03-08
US60/274,551 2001-03-08
US27850701P 2001-03-23 2001-03-23
US60/278,507 2001-03-23
US28059701P 2001-03-30 2001-03-30
US60/280,597 2001-03-30
US28110701P 2001-04-02 2001-04-02
US60/281,107 2001-04-02
US28212101P 2001-04-06 2001-04-06
US60/282,121 2001-04-06

Publications (2)

Publication Number Publication Date
WO2002063004A2 WO2002063004A2 (en) 2002-08-15
WO2002063004A3 true WO2002063004A3 (en) 2003-09-25

Family

ID=27569524

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/003635 WO2002063004A2 (en) 2001-02-07 2002-02-06 G-protein coupled receptors

Country Status (4)

Country Link
EP (1) EP1366165A2 (en)
JP (1) JP2005503111A (en)
CA (1) CA2437717A1 (en)
WO (1) WO2002063004A2 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1372690A4 (en) * 2001-03-01 2005-08-24 Millennium Pharm Inc 93870, a human g-protein coupled receptor and uses therefor
US7803982B2 (en) 2001-04-20 2010-09-28 The Mount Sinai School Of Medicine Of New York University T1R3 transgenic animals, cells and related methods
AU2003236351A1 (en) * 2002-04-03 2003-10-27 Banyu Pharmaceutical Co., Ltd. Novel g protein-coupled receptor gene and protein bg8
JP2004242644A (en) * 2002-12-18 2004-09-02 National Institute Of Advanced Industrial & Technology Guanosine triphosphate binding protein coupled receptor
WO2004056866A1 (en) * 2002-12-20 2004-07-08 Geneos Oy Asthma susceptibility locus
WO2004104596A2 (en) * 2003-05-22 2004-12-02 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with igs70 (igs70)
US7189539B2 (en) 2003-11-25 2007-03-13 Bristol-Myers Squibb Company Polynucleotide encoding a human relaxin receptor, HGPRBMY5v1

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999048921A1 (en) * 1998-03-26 1999-09-30 The Board Of Trustees Of The Leland Stanford Junior University Novel mammalian g-protein coupled receptors having extracellular leucine rich repeat regions
WO2000015793A2 (en) * 1998-09-17 2000-03-23 Incyte Pharmaceuticals, Inc. Human gpcr proteins
WO2001036471A2 (en) * 1999-11-17 2001-05-25 Arena Pharmaceuticals, Inc. Endogenous and non-endogenous versions of human g protein-coupled receptors
WO2002004640A1 (en) * 2000-07-07 2002-01-17 Takeda Chemical Industries, Ltd. Novel g protein-coupled receptor protein and dna thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999048921A1 (en) * 1998-03-26 1999-09-30 The Board Of Trustees Of The Leland Stanford Junior University Novel mammalian g-protein coupled receptors having extracellular leucine rich repeat regions
WO2000015793A2 (en) * 1998-09-17 2000-03-23 Incyte Pharmaceuticals, Inc. Human gpcr proteins
WO2001036471A2 (en) * 1999-11-17 2001-05-25 Arena Pharmaceuticals, Inc. Endogenous and non-endogenous versions of human g protein-coupled receptors
WO2002004640A1 (en) * 2000-07-07 2002-01-17 Takeda Chemical Industries, Ltd. Novel g protein-coupled receptor protein and dna thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
DATABASE GENESEQ [online] 23 May 2002 (2002-05-23), "Human G protein-coupled receptor TGR17-6 protein SEQ ID NO:15", XP002233600, retrieved from GENESEQ Database accession no. ABB06255 *

Also Published As

Publication number Publication date
JP2005503111A (en) 2005-02-03
EP1366165A2 (en) 2003-12-03
WO2002063004A2 (en) 2002-08-15
CA2437717A1 (en) 2002-08-15

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