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WO2002061425A3 - Diagnostic method and apparatus for detecting biogenic amines - Google Patents

Diagnostic method and apparatus for detecting biogenic amines Download PDF

Info

Publication number
WO2002061425A3
WO2002061425A3 PCT/IL2002/000087 IL0200087W WO02061425A3 WO 2002061425 A3 WO2002061425 A3 WO 2002061425A3 IL 0200087 W IL0200087 W IL 0200087W WO 02061425 A3 WO02061425 A3 WO 02061425A3
Authority
WO
WIPO (PCT)
Prior art keywords
biogenic amines
amounts
derived
measured parameters
diagnostic
Prior art date
Application number
PCT/IL2002/000087
Other languages
French (fr)
Other versions
WO2002061425A2 (en
Inventor
Avraham Lorber
Zeev Karpas
Original Assignee
Scent Ltd Q
Avraham Lorber
Zeev Karpas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IL14123301A external-priority patent/IL141233A0/en
Priority claimed from IL14669801A external-priority patent/IL146698A0/en
Application filed by Scent Ltd Q, Avraham Lorber, Zeev Karpas filed Critical Scent Ltd Q
Priority to AU2002230059A priority Critical patent/AU2002230059A1/en
Priority to US10/079,624 priority patent/US20020120406A1/en
Publication of WO2002061425A2 publication Critical patent/WO2002061425A2/en
Publication of WO2002061425A3 publication Critical patent/WO2002061425A3/en
Priority to US12/456,591 priority patent/US8942926B2/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)

Abstract

Diagnostic method, based on the amounts of biogenic amines that are contained in a body fluid or other sample. A number of measured parameters related to the desired diagnostic information are derived from the amounts. For each diagnostic information desired, an input consisting of the identification of the diagnostic information is provided. The input is compared to the measured parameters and a diagnostic response is derived from the comparison. The measured parameters may be derived from the amounts of the biogenic amines according to a program stored in a memory. The detection of the less volatile amines and their separation from the more volatile ones may advantageously be enhanced by successively adding a base and an acid, in either possible succession, to the sample and analyzing the vapors emitted by the sample under heating.
PCT/IL2002/000087 2001-02-01 2002-01-31 Diagnostic method and apparatus for detecting biogenic amines WO2002061425A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
AU2002230059A AU2002230059A1 (en) 2001-02-01 2002-01-31 Diagnostic method and apparatus for detecting biogenic amines
US10/079,624 US20020120406A1 (en) 2001-02-01 2002-02-20 Diagnostic method and apparatus
US12/456,591 US8942926B2 (en) 2001-02-01 2009-06-18 Method for the diagnosis of pathological conditions in animals

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
IL14123301A IL141233A0 (en) 2001-02-01 2001-02-01 Diagnostic method and apparatus
IL141233 2001-02-01
IL146698 2001-11-22
IL14669801A IL146698A0 (en) 2001-11-22 2001-11-22 Method for selectively determining semi-volatile biogenic amines

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US09/813,523 Continuation-In-Part US7056745B2 (en) 2001-02-01 2001-03-21 Diagnostic method and apparatus

Publications (2)

Publication Number Publication Date
WO2002061425A2 WO2002061425A2 (en) 2002-08-08
WO2002061425A3 true WO2002061425A3 (en) 2003-02-27

Family

ID=26324004

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IL2002/000087 WO2002061425A2 (en) 2001-02-01 2002-01-31 Diagnostic method and apparatus for detecting biogenic amines

Country Status (2)

Country Link
AU (1) AU2002230059A1 (en)
WO (1) WO2002061425A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020120406A1 (en) 2001-02-01 2002-08-29 Avraham Lorber Diagnostic method and apparatus
US8942926B2 (en) * 2001-02-01 2015-01-27 Q-Scent Ltd. Method for the diagnosis of pathological conditions in animals
FR3008317B1 (en) * 2013-07-15 2017-04-28 Univ D'auvergne Clermont I USE OF MICROORGANISMS TO DECREASE THE TRIMETHYLAMINE RATE IN A HUMAN BODY CAVITY, IN PARTICULAR FOR THE TREATMENT OF TRIMETHYLAMINURIA OR BACTERIAL VAGINOSIS AND THE PREVENTION OF CARDIOVASCULAR DISEASES
WO2014082773A1 (en) 2012-11-30 2014-06-05 Universite D'auvergne Clermont I Use of microorganisms for reducing the level of trimethylamine in a human body cavity, in particular for the treatment of trimethylaminuria or of bacterial vaginosis and the prevention of cardiovascular diseases
WO2017178032A1 (en) * 2015-04-22 2017-10-19 Lachlak Nassira Procedure for detecting infections or diseases in the field of gynaecology using volatile organic compounds from vaginal exudates

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5856616A (en) * 1997-03-21 1999-01-05 The United States Of America As Represented By The Secretary Of The Army Hand-held temperature programmable modular gas chromatograph
WO2000020852A1 (en) * 1998-10-02 2000-04-13 California Institute Of Technology Conductive organic sensors, arrays and methods of use

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5856616A (en) * 1997-03-21 1999-01-05 The United States Of America As Represented By The Secretary Of The Army Hand-held temperature programmable modular gas chromatograph
WO2000020852A1 (en) * 1998-10-02 2000-04-13 California Institute Of Technology Conductive organic sensors, arrays and methods of use

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
LAWRENCE P J ET AL: "Spectrophotometric quantitation of vaginal fluid trimethylamine and comparative performance of olfactory trimethylamine (KOH whiff test) detection and a new colorimetric chemical test.", CLINICAL CHEMISTRY, vol. 45, no. 6 PART 2, June 1999 (1999-06-01), 51st Annual Meeting of the American Association of Clinical Chemistry;New Orleans, Louisiana, USA; July 25-29, 1999, pages A162, XP001118327, ISSN: 0009-9147 *

Also Published As

Publication number Publication date
WO2002061425A2 (en) 2002-08-08
AU2002230059A1 (en) 2002-08-12

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