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WO2002056991A3 - Systems and methods for performing electrokinetic chromatography - Google Patents

Systems and methods for performing electrokinetic chromatography Download PDF

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Publication number
WO2002056991A3
WO2002056991A3 PCT/US2002/001259 US0201259W WO02056991A3 WO 2002056991 A3 WO2002056991 A3 WO 2002056991A3 US 0201259 W US0201259 W US 0201259W WO 02056991 A3 WO02056991 A3 WO 02056991A3
Authority
WO
WIPO (PCT)
Prior art keywords
methods
systems
electrokinetic chromatography
performing electrokinetic
reagents
Prior art date
Application number
PCT/US2002/001259
Other languages
French (fr)
Other versions
WO2002056991A2 (en
Inventor
Wolfgang K Goetzinger
Cai Hong
Original Assignee
Arqule Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arqule Inc filed Critical Arqule Inc
Priority to AU2002239939A priority Critical patent/AU2002239939A1/en
Publication of WO2002056991A2 publication Critical patent/WO2002056991A2/en
Publication of WO2002056991A3 publication Critical patent/WO2002056991A3/en

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/26Conditioning of the fluid carrier; Flow patterns
    • G01N30/28Control of physical parameters of the fluid carrier
    • G01N30/34Control of physical parameters of the fluid carrier of fluid composition, e.g. gradient
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416Systems
    • G01N27/447Systems using electrophoresis
    • G01N27/44704Details; Accessories
    • G01N27/44747Composition of gel or of carrier mixture
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/26Conditioning of the fluid carrier; Flow patterns
    • G01N30/28Control of physical parameters of the fluid carrier
    • G01N2030/285Control of physical parameters of the fluid carrier electrically driven carrier

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)

Abstract

Reagents and methods for performing electrokinetic chromatography are provided. The reagents of the invention comprise at least one organic acid and at least one organic base, and are substantially free of inorganic ions.
PCT/US2002/001259 2001-01-16 2002-01-16 Systems and methods for performing electrokinetic chromatography WO2002056991A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002239939A AU2002239939A1 (en) 2001-01-16 2002-01-16 Systems and methods for performing electrokinetic chromatography

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US26198701P 2001-01-16 2001-01-16
US60/261,987 2001-01-16

Publications (2)

Publication Number Publication Date
WO2002056991A2 WO2002056991A2 (en) 2002-07-25
WO2002056991A3 true WO2002056991A3 (en) 2003-05-01

Family

ID=22995704

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/001259 WO2002056991A2 (en) 2001-01-16 2002-01-16 Systems and methods for performing electrokinetic chromatography

Country Status (2)

Country Link
AU (1) AU2002239939A1 (en)
WO (1) WO2002056991A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002951153A0 (en) * 2002-09-02 2002-09-19 Proteome Systems Intellectual Property Pty Ltd An electrophoresis gel having improved swelling properties

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6083372A (en) * 1995-07-18 2000-07-04 Waters Investments Limited Reagents and methods for performing electrokinetic chromatography

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6083372A (en) * 1995-07-18 2000-07-04 Waters Investments Limited Reagents and methods for performing electrokinetic chromatography

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
MUIJSELAAR P G ET AL: "Micelles as pseudo-stationary phases in micellar electrokinetic chromatography", JOURNAL OF CHROMATOGRAPHY A, ELSEVIER SCIENCE, NL, vol. 780, no. 1-2, 12 September 1997 (1997-09-12), pages 41 - 61, XP004092092, ISSN: 0021-9673 *
MUIJSELAAR P G ET AL: "Separation of hydrophobic compounds by electrokinetic chromatography with tetraalkylammonium ions", JOURNAL OF CHROMATOGRAPHY A, ELSEVIER SCIENCE, NL, vol. 764, no. 2, 14 March 1997 (1997-03-14), pages 323 - 329, XP004057245, ISSN: 0021-9673 *
PETERSON A G ET AL: "Enantiomeric separations of basic pharmaceutical drugs by micellar electrokinetic chromatography using a chiral surfactant, N-dodecoxycarbonylvaline", JOURNAL OF CHROMATOGRAPHY B: BIOMEDICAL APPLICATIONS, ELSEVIER SCIENCE PUBLISHERS, NL, vol. 683, no. 1, 9 August 1996 (1996-08-09), pages 15 - 28, XP004044236, ISSN: 0378-4347 *
REN H ET AL: "Capillary electrophoretic separation of polynuclear aromatic hydrocarbons using sodium cholate in mixed aqueous-organic buffers", JOURNAL OF CHROMATOGRAPHY A, ELSEVIER SCIENCE, NL, vol. 817, no. 1-2, 21 August 1998 (1998-08-21), pages 307 - 311, XP004139751, ISSN: 0021-9673 *
TRONE M D ET AL: "Characterization of chemical selectivity in micellar electrokinetic chromatography - VI. Effects of surfactant counter-ion", JOURNAL OF CHROMATOGRAPHY, ELSEVIER SCIENCE PUBLISHERS B.V. AMSTERDAM, NL, vol. 888, no. 1-2, 4 August 2000 (2000-08-04), pages 229 - 240, XP004209878, ISSN: 0021-9673 *

Also Published As

Publication number Publication date
AU2002239939A1 (en) 2002-07-30
WO2002056991A2 (en) 2002-07-25

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