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WO2002054078A3 - Method for determining skin ageing in vitro - Google Patents

Method for determining skin ageing in vitro Download PDF

Info

Publication number
WO2002054078A3
WO2002054078A3 PCT/EP2001/014812 EP0114812W WO02054078A3 WO 2002054078 A3 WO2002054078 A3 WO 2002054078A3 EP 0114812 W EP0114812 W EP 0114812W WO 02054078 A3 WO02054078 A3 WO 02054078A3
Authority
WO
WIPO (PCT)
Prior art keywords
skin
ageing
stress
skin ageing
vitro
Prior art date
Application number
PCT/EP2001/014812
Other languages
German (de)
French (fr)
Other versions
WO2002054078A2 (en
Inventor
Dirk Petersohn
Guenter Schmitt
Thomas Foerster
Original Assignee
Henkel Kommandigesellschaft Au
Dirk Petersohn
Guenter Schmitt
Thomas Foerster
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Henkel Kommandigesellschaft Au, Dirk Petersohn, Guenter Schmitt, Thomas Foerster filed Critical Henkel Kommandigesellschaft Au
Priority to AU2002219190A priority Critical patent/AU2002219190A1/en
Publication of WO2002054078A2 publication Critical patent/WO2002054078A2/en
Publication of WO2002054078A3 publication Critical patent/WO2002054078A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/148—Screening for cosmetic compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

The invention relates to a method for determining skin stress and/or skin ageing in humans in vitro. The invention also relates to test-kits and biochips for determining skin stress and/or skin ageing in addition to the uses of proteins, mRNA molecules or fragments of proteins or mRNA molecules as a stress and/or ageing marker on the skin. The invention further relates to a method for analysing the effectiveness of cosmetic or pharmaceutical active substances against skin stress and/or skin ageing, and a screening method for identifying cosmetic or pharmaceutical active ingredients against skin stress and/or skin ageing, in addition to a method for producing a cosmetic or pharmaceutical preparation against skin stress and/or skin ageing.
PCT/EP2001/014812 2001-01-03 2001-12-14 Method for determining skin ageing in vitro WO2002054078A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002219190A AU2002219190A1 (en) 2001-01-03 2001-12-14 Method for determining skin ageing in vitro

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10100122A DE10100122A1 (en) 2001-01-03 2001-01-03 Method for determining skin aging in vitro
DE10100122.3 2001-01-03

Publications (2)

Publication Number Publication Date
WO2002054078A2 WO2002054078A2 (en) 2002-07-11
WO2002054078A3 true WO2002054078A3 (en) 2003-02-27

Family

ID=7669724

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2001/014812 WO2002054078A2 (en) 2001-01-03 2001-12-14 Method for determining skin ageing in vitro

Country Status (3)

Country Link
AU (1) AU2002219190A1 (en)
DE (1) DE10100122A1 (en)
WO (1) WO2002054078A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2847269B1 (en) * 2002-11-19 2006-07-28 Coletica METHOD FOR IDENTIFYING AN EVENTUAL MODIFICATION OF AT LEAST ONE BIOLOGICAL PARAMETER USING YOUNG AND AGE LIVING CELLS
FR2847268B1 (en) * 2002-11-19 2006-09-29 Coletica METHOD FOR IDENTIFYING AN EVENTUALLY MODIFICATION OF AT LEAST ONE BIOLOGICAL PARAMETER USING LIVING CELLS SUBJECT TO STRESS AND LIVING CELLS NOT SUBJECT TO THIS SAME STRESS
FR2924613B1 (en) * 2007-12-10 2012-12-21 Oreal COSMETIC USE OF PROTEINS OF HSP27 TYPE.
JP5653684B2 (en) * 2010-08-21 2015-01-14 日本メナード化粧品株式会社 How to check the degree of skin damage

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992015700A1 (en) * 1991-02-28 1992-09-17 Anticancer, Inc. A native-state histoculturing method for skin
WO1998053103A1 (en) * 1997-05-21 1998-11-26 Clontech Laboratories, Inc. Nucleic acid arrays
WO1999039210A1 (en) * 1998-01-29 1999-08-05 Miller, Samuel High density arrays for proteome analysis and methods and compositions therefor

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4603146A (en) * 1984-05-16 1986-07-29 Kligman Albert M Methods for retarding the effects of aging of the skin
DE69131692T3 (en) * 1991-05-16 2004-09-23 Senetek, Plc METHOD AND COMPOSITION FOR IMPROVING THE UNEFFECTIVE IMPACT OF AGING
WO1995016659A1 (en) * 1993-12-15 1995-06-22 Avon Products, Inc. Novel retinoid conjugate compounds and methods for treating skin aging
DE19742025A1 (en) * 1997-09-24 1999-03-25 Beiersdorf Ag Use of flavone or flavanone derivatives to treat or prevent undesirable skin pigmentation

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992015700A1 (en) * 1991-02-28 1992-09-17 Anticancer, Inc. A native-state histoculturing method for skin
WO1998053103A1 (en) * 1997-05-21 1998-11-26 Clontech Laboratories, Inc. Nucleic acid arrays
WO1999039210A1 (en) * 1998-01-29 1999-08-05 Miller, Samuel High density arrays for proteome analysis and methods and compositions therefor

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
BOXMAN I L A ET AL: "Proteomic analysis of skin irritation reveals the induction of HSP27 by sodium lauryl sulphate in human skin.", THE BRITISH JOURNAL OF DERMATOLOGY. ENGLAND MAY 2002, vol. 146, no. 5, May 2002 (2002-05-01), pages 777 - 785, XP002217295, ISSN: 0007-0963 *
COURCHESNE P L ET AL: "Identification of Proteins by Matrix-Assisted Laser Desorption/Ionization Mass Spectroscopy Using Peptide and Fragment Ion Masses (from 2-D Proteome Analysis Protocols, Ed. A. J. Link)", METHODS IN MOLECULAR BIOLOGY, HUMANA PRESS INC., CLIFTON, NJ, US, vol. 112, 1999, pages 487 - 511, XP002103063 *
FENGA C ET AL: "Heat Shock Protein 27 is overexpressed in the skin of bitumen exposed workers. Early observations.", BOLLETTINO DELLA SOCIETA ITALIANA DI BIOLOGIA SPERIMENTALE. ITALY 2000 NOV-DEC, vol. 76, no. 11-12, November 2000 (2000-11-01), pages 81 - 86, XP001117652, ISSN: 0037-8771 *
HAYDEN P J ET AL: "Changes in cancer-related gene expression in an in vitro human skin model following UVB-irradiation.", JOURNAL OF INVESTIGATIVE DERMATOLOGY, vol. 114, no. 4, April 2000 (2000-04-01), 61st Annual Meeting of the Society for Investigative Dermatology.;Chicago, Illinois, USA; May 10-14, 2000, pages 824, XP002217294, ISSN: 0022-202X *
KATZ ANNE B ET AL: "A partial catalog of proteins secreted by epidermal keratinocytes in culture.", JOURNAL OF INVESTIGATIVE DERMATOLOGY, vol. 112, no. 5, May 1999 (1999-05-01), pages 818 - 821, XP002217163, ISSN: 0022-202X *
TRAUTINGER FRANZ ET AL: "Stress proteins in the cellular response to ultraviolet radiation.", JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B BIOLOGY, vol. 35, no. 3, 1996, pages 141 - 148, XP002217161, ISSN: 1011-1344 *
WEIDNER CHRISTIAN ET AL: "Acute effects of substance P and calcitonin gene-related peptide in human skin: A microdialysis study.", JOURNAL OF INVESTIGATIVE DERMATOLOGY, vol. 115, no. 6, December 2000 (2000-12-01), pages 1015 - 1020, XP002217162, ISSN: 0022-202X *

Also Published As

Publication number Publication date
DE10100122A1 (en) 2002-07-11
AU2002219190A1 (en) 2002-07-16
WO2002054078A2 (en) 2002-07-11

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