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WO2002053719A3 - Cytoskeleton-associated proteins - Google Patents

Cytoskeleton-associated proteins Download PDF

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Publication number
WO2002053719A3
WO2002053719A3 PCT/US2002/000178 US0200178W WO02053719A3 WO 2002053719 A3 WO2002053719 A3 WO 2002053719A3 US 0200178 W US0200178 W US 0200178W WO 02053719 A3 WO02053719 A3 WO 02053719A3
Authority
WO
WIPO (PCT)
Prior art keywords
csap
cytoskeleton
associated proteins
provides
polynucleotides
Prior art date
Application number
PCT/US2002/000178
Other languages
French (fr)
Other versions
WO2002053719A2 (en
Inventor
Dyung Aina M Lu
Mariah R Baughn
Monique G Yao
Li Ding
Cynthia D Honchell
Henry Yue
Y Tom Tang
Bridget A Warren
Brendan M Duggan
Yuming Xu
Narinder K Chawla
Jennifer A Griffin
Elizabeth A Stewart
Ameena R Gandhi
Farrah A Khan
Kavitha Thangavelu
Craig H Ison
Yalda Azimzai
April J A Hafalia
Kimberly J Gietzen
Preeti G Lal
Madhusudan M Sanjanwala
Vicki S Elliott
Original Assignee
Incyte Genomics Inc
Dyung Aina M Lu
Mariah R Baughn
Monique G Yao
Li Ding
Cynthia D Honchell
Henry Yue
Y Tom Tang
Bridget A Warren
Brendan M Duggan
Yuming Xu
Narinder K Chawla
Jennifer A Griffin
Elizabeth A Stewart
Ameena R Gandhi
Farrah A Khan
Kavitha Thangavelu
Craig H Ison
Yalda Azimzai
April J A Hafalia
Kimberly J Gietzen
Preeti G Lal
Madhusudan M Sanjanwala
Vicki S Elliott
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Genomics Inc, Dyung Aina M Lu, Mariah R Baughn, Monique G Yao, Li Ding, Cynthia D Honchell, Henry Yue, Y Tom Tang, Bridget A Warren, Brendan M Duggan, Yuming Xu, Narinder K Chawla, Jennifer A Griffin, Elizabeth A Stewart, Ameena R Gandhi, Farrah A Khan, Kavitha Thangavelu, Craig H Ison, Yalda Azimzai, April J A Hafalia, Kimberly J Gietzen, Preeti G Lal, Madhusudan M Sanjanwala, Vicki S Elliott filed Critical Incyte Genomics Inc
Priority to US10/250,613 priority Critical patent/US20040096828A1/en
Publication of WO2002053719A2 publication Critical patent/WO2002053719A2/en
Publication of WO2002053719A3 publication Critical patent/WO2002053719A3/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/93Ligases (6)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/05Animals comprising random inserted nucleic acids (transgenic)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The invention provides human cytoskeleton-associated proteins (CSAP) and polynucleotides which identify and encode CSAP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of CSAP.
PCT/US2002/000178 2001-01-04 2002-01-04 Cytoskeleton-associated proteins WO2002053719A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US10/250,613 US20040096828A1 (en) 2002-01-04 2002-01-04 Cytoskeleton-associated proteins

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US26008501P 2001-01-04 2001-01-04
US60/260,085 2001-01-04
US26855401P 2001-02-13 2001-02-13
US60/268,554 2001-02-13
US26911101P 2001-02-14 2001-02-14
US60/269,111 2001-02-14
US27121101P 2001-02-23 2001-02-23
US60/271,211 2001-02-23

Publications (2)

Publication Number Publication Date
WO2002053719A2 WO2002053719A2 (en) 2002-07-11
WO2002053719A3 true WO2002053719A3 (en) 2003-07-24

Family

ID=27500663

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/000178 WO2002053719A2 (en) 2001-01-04 2002-01-04 Cytoskeleton-associated proteins

Country Status (1)

Country Link
WO (1) WO2002053719A2 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60220621T2 (en) 2001-11-09 2008-03-06 Proteologics, Inc. Posh nucleic acid, polypeptides and related methods
EP1459758B1 (en) 2001-12-28 2009-02-25 Asubio Pharma Co., Ltd. Cofilin for promoting the proliferation and/or differentiation of hematopoietic stem cells and/or hematopoietic precursor cells
US6657054B1 (en) * 2002-06-10 2003-12-02 Origene Technologies, Inc. Regulated angiogenesis genes and polypeptides
WO2003106667A2 (en) * 2002-06-12 2003-12-24 Bayer Healthcare Ag Regulation of human subtilase-like serine protease
WO2006000955A1 (en) 2004-06-24 2006-01-05 Philips Intellectual Property & Standards Gmbh A method for signaling thestatus of a subcarrier in a mc network and a method for adaptively allocating the subcarriers in a mc network
JP5099534B2 (en) * 2005-11-17 2012-12-19 独立行政法人産業技術総合研究所 Use of Kank3 gene for cancer therapy, cancer detection and drug discovery
CN109811061B (en) * 2019-02-20 2023-05-09 新疆农业大学 Detection method and application of COIL gene-specific SNP markers, litter size traits of Hetian Qiaoda red sheep

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000017355A2 (en) * 1998-09-18 2000-03-30 Incyte Pharmaceuticals, Inc. Human cytoskeleton associated proteins
WO2000073450A2 (en) * 1999-05-27 2000-12-07 Incyte Genomics, Inc. Cytoskeleton-associated proteins
WO2001057190A2 (en) * 2000-02-03 2001-08-09 Hyseq, Inc. Novel nucleic acids and polypeptides

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000017355A2 (en) * 1998-09-18 2000-03-30 Incyte Pharmaceuticals, Inc. Human cytoskeleton associated proteins
WO2000073450A2 (en) * 1999-05-27 2000-12-07 Incyte Genomics, Inc. Cytoskeleton-associated proteins
WO2001057190A2 (en) * 2000-02-03 2001-08-09 Hyseq, Inc. Novel nucleic acids and polypeptides

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL [online] EBI; 21 December 1999 (1999-12-21), MAS. C.R. ET AL.: "Rattus norvegicus tubulin tyrosine ligase (Ttl) mRNA, complete cds.", XP002224906, Database accession no. AF207605 *
DATABASE SWISSPROT [online] 1 October 1994 (1994-10-01), ERSFELD K. ET AL.: "Tubulin--tyrosine ligase (EC 6.3.2.25) (TTL).", XP002224905, Database accession no. P38160 *
ERSFELD K ET AL: "Characterization of the tubulin-tyrosine ligase.", THE JOURNAL OF CELL BIOLOGY. UNITED STATES FEB 1993, vol. 120, no. 3, 3 February 1993 (1993-02-03), pages 725 - 732, XP009003321, DOI: doi:10.1083/jcb.120.3.725 *
MOORE J D ET AL: "KINESIN PROTEINS: A PHYLUM OF MOTORS FOR MICROTUBULE-BASED MOTILITY", BIOESSAYS, CAMBRIDGE, GB, vol. 18, no. 3, 1996, pages 207 - 219, XP000952735, ISSN: 0265-9247 *
MURPHY M ET AL: "Suppression subtractive hybridization identifies high glucose levels as a stimulus for expression of connective tissue growth factor and other genes in human mesangial cells", JOURNAL OF BIOLOGICAL CHEMISTRY, AMERICAN SOCIETY OF BIOLOGICAL CHEMISTS, BALTIMORE, MD, US, vol. 274, no. 9, 26 February 1999 (1999-02-26), pages 5830 - 5834, XP002142860, ISSN: 0021-9258 *

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Publication number Publication date
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