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WO2002053115A1 - Composition utilisee dans le cadre de la desaccoutumance au tabac - Google Patents

Composition utilisee dans le cadre de la desaccoutumance au tabac Download PDF

Info

Publication number
WO2002053115A1
WO2002053115A1 PCT/DE2001/004878 DE0104878W WO02053115A1 WO 2002053115 A1 WO2002053115 A1 WO 2002053115A1 DE 0104878 W DE0104878 W DE 0104878W WO 02053115 A1 WO02053115 A1 WO 02053115A1
Authority
WO
WIPO (PCT)
Prior art keywords
agent
preparation
silver
smokers
habit
Prior art date
Application number
PCT/DE2001/004878
Other languages
German (de)
English (en)
Inventor
Michael Mühleisen
Original Assignee
Muehleisen Michael
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Muehleisen Michael filed Critical Muehleisen Michael
Publication of WO2002053115A1 publication Critical patent/WO2002053115A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K6/00—Preparations for dentistry
    • A61K6/20—Protective coatings for natural or artificial teeth, e.g. sealings, dye coatings or varnish
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36—Carboxylic acids; Salts or anhydrides thereof
    • A61K8/365—Hydroxycarboxylic acids; Ketocarboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0063—Periodont

Definitions

  • the invention relates to an agent for application in the throat of a person, in particular for smoking cessation, with a depot for a silver salt.
  • a means of the type mentioned is known for example from DE 40 11 543 AI.
  • a silver salt is suggested there to support smoking cessation. This can be used, for example, as a chewing gum mixture or as mouthwash or as a toothpaste base.
  • metal or silver salts as bactericidal agent is also described in DE 196 40 365 AI and in US 6,153,210.
  • the problem with all the means proposed in these publications is that long-term success in smoking cessation is not ensured.
  • the invention is therefore based on the object of providing an agent of the type mentioned at the outset which has a particularly long-term and sustainable effect.
  • the agent is designed as a tooth varnish for permanent application to the teeth.
  • the result of this is that the test person cannot easily remove the agent himself and that the person who decides to quit smoking is bound to the decision made at least for a certain period of time, thereby significantly increasing the likelihood of quitting smoking.
  • the known agents such as chewing gum and mouthwash, the test subjects have to use the agent again at short intervals. This is avoided according to the invention.
  • the dental enamel is preferably designed as an organic carrier substrate.
  • Preferred silver salt is silver lactate in the highest purity level.
  • Silver lactate is contained in a defined concentration in the agent according to the invention.
  • This silver lactate has the property that when it comes into contact with tobacco smoke it causes an unpleasant taste in the throat of humans. If the silver lactate does not come into contact with tobacco smoke, it is tasteless.
  • the effective agent in the silver lactate is silver or the silver ion.
  • the agent for permanent application according to the invention is thus suitable for supporting a person in the weaning of tobacco smoke. Due to the property of the agent to apply it permanently in the throat for a defined longer period of time, the agent provides a long-term depot for silver lactate. The active agent gradually emerges from this depot in small amounts over a long period of time, for example over a period of four weeks. It is advantageously ensured over this long period that an unpleasant taste arises when a device comes into contact with tobacco smoke.
  • the concentration of the silver lactate in the average is about 0.5 to 2% by weight (% by weight), preferably 1% by weight (% by weight). This concentration has demonstrably shown that the desired effect of the agent according to the invention is ensured over a sufficiently long period of time, for example four weeks.
  • the agent is designed as a lacquer produced from an organic carrier. This can be applied to a person's teeth in particular and forms a long-lasting coating on the teeth. The silver lactate contained in this long-lasting coating is released gradually and in a defined manner.
  • Another aspect of the invention is to provide a toothbrush, in particular a single-use toothbrush, with a pre-applied agent with the above-mentioned features.
  • the agent can be permanently applied to the teeth with the aid of a toothbrush and is easy and safe for the user to apply.

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Nutrition Science (AREA)
  • Birds (AREA)
  • Physiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Emergency Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Cosmetics (AREA)
  • Brushes (AREA)
  • Dental Tools And Instruments Or Auxiliary Dental Instruments (AREA)
  • Dental Preparations (AREA)

Abstract

L'invention concerne un agent s'utilisant dans la désaccoutumance au tabac, qui s'applique dans la cavité pharyngée d'un être humain, avec une réserve pour un sel d'argent. Ledit agent est amélioré du fait qu'il se présente sous forme de vernis dentaire à appliquer de manière durable sur les dents et peut par conséquen être utilisé suffisamment longtemps.
PCT/DE2001/004878 2001-01-04 2001-12-21 Composition utilisee dans le cadre de la desaccoutumance au tabac WO2002053115A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE20100088.1 2001-01-04
DE20100088U DE20100088U1 (de) 2001-01-04 2001-01-04 Mittel zum dauerhaften Auftragen im Rachenraum eines Menschen

Publications (1)

Publication Number Publication Date
WO2002053115A1 true WO2002053115A1 (fr) 2002-07-11

Family

ID=7951201

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/DE2001/004878 WO2002053115A1 (fr) 2001-01-04 2001-12-21 Composition utilisee dans le cadre de la desaccoutumance au tabac

Country Status (2)

Country Link
DE (1) DE20100088U1 (fr)
WO (1) WO2002053115A1 (fr)

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990014076A1 (fr) * 1989-05-25 1990-11-29 A/S Dumex (Dumex Ltd.) Preparation pour le traitement d'infection fongiques
DE4011543A1 (de) * 1990-04-10 1991-10-17 Michael Dipl Ing Radermacher Mittel zur unterstuetzung der raucherentwoehnung
US5122366A (en) * 1989-01-21 1992-06-16 The Arab Pharmaceutical Company Antismoke mouth wash comprising silver nitrate and propylene glycol
WO1995001788A1 (fr) * 1993-07-09 1995-01-19 Trustees Of Tufts College Procedes et articles d'administration de medicament dans la cavite buccale
GB2288119A (en) * 1994-04-05 1995-10-11 Izhak Blank Compositions applied to the oral cavity

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4832994A (en) 1987-09-02 1989-05-23 Fey Michael S Anti-smoking oral composition
US4980172A (en) 1989-05-12 1990-12-25 Fey Michael S Anti-smoking oral composition
DE19640365A1 (de) 1996-09-30 1998-04-02 Basf Ag Polymer-Wasserstoffperoxid-Komplexe
US6153210A (en) 1997-08-14 2000-11-28 Periodontix, Inc. Use of locally delivered metal ions for treatment of periodontal disease

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5122366A (en) * 1989-01-21 1992-06-16 The Arab Pharmaceutical Company Antismoke mouth wash comprising silver nitrate and propylene glycol
WO1990014076A1 (fr) * 1989-05-25 1990-11-29 A/S Dumex (Dumex Ltd.) Preparation pour le traitement d'infection fongiques
DE4011543A1 (de) * 1990-04-10 1991-10-17 Michael Dipl Ing Radermacher Mittel zur unterstuetzung der raucherentwoehnung
WO1995001788A1 (fr) * 1993-07-09 1995-01-19 Trustees Of Tufts College Procedes et articles d'administration de medicament dans la cavite buccale
GB2288119A (en) * 1994-04-05 1995-10-11 Izhak Blank Compositions applied to the oral cavity

Also Published As

Publication number Publication date
DE20100088U1 (de) 2001-03-29

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