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WO2002052003A3 - Regulation of human calcium channel - Google Patents

Regulation of human calcium channel Download PDF

Info

Publication number
WO2002052003A3
WO2002052003A3 PCT/EP2001/015088 EP0115088W WO02052003A3 WO 2002052003 A3 WO2002052003 A3 WO 2002052003A3 EP 0115088 W EP0115088 W EP 0115088W WO 02052003 A3 WO02052003 A3 WO 02052003A3
Authority
WO
WIPO (PCT)
Prior art keywords
human calcium
calcium channel
regulation
disorders
reagents
Prior art date
Application number
PCT/EP2001/015088
Other languages
French (fr)
Other versions
WO2002052003A2 (en
Inventor
Alex Smolyar
Original Assignee
Bayer Ag
Alex Smolyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag, Alex Smolyar filed Critical Bayer Ag
Publication of WO2002052003A2 publication Critical patent/WO2002052003A2/en
Publication of WO2002052003A3 publication Critical patent/WO2002052003A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Reagents which regulate human calcium channels and reagents which bind to human calcium channel-like gene products can play a role in preventing, ameliorating, or correcting dysfunctions or diseases including, but not limited to, cancer, CNS disorders, cardiovascular disorders, and hemotological disorders.
PCT/EP2001/015088 2000-12-26 2001-12-19 Regulation of human calcium channel WO2002052003A2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US25729700P 2000-12-26 2000-12-26
US60/257,297 2000-12-26
US28011301P 2001-04-02 2001-04-02
US60/280,113 2001-04-02

Publications (2)

Publication Number Publication Date
WO2002052003A2 WO2002052003A2 (en) 2002-07-04
WO2002052003A3 true WO2002052003A3 (en) 2002-12-27

Family

ID=26945881

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2001/015088 WO2002052003A2 (en) 2000-12-26 2001-12-19 Regulation of human calcium channel

Country Status (1)

Country Link
WO (1) WO2002052003A2 (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999046383A1 (en) * 1998-03-13 1999-09-16 Brown University Research Foundation Human n-type calcium channel isoform and uses thereof
WO2002010389A2 (en) * 2000-07-28 2002-02-07 Lexicon Genetics Incorporated Human ion channel proteins and polynucleotides encoding the same

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999046383A1 (en) * 1998-03-13 1999-09-16 Brown University Research Foundation Human n-type calcium channel isoform and uses thereof
WO2002010389A2 (en) * 2000-07-28 2002-02-07 Lexicon Genetics Incorporated Human ion channel proteins and polynucleotides encoding the same

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL NUCLEIC ACIDS [online] 1 July 2000 (2000-07-01), XP002216680, retrieved from EMBL DATABASE Database accession no. BE141734 *
DATABASE EMBL PROTEIN [online] 1 October 2000 (2000-10-01), XP002216679, retrieved from EMBL DATABASE Database accession no. Q9NT82 *
ISHIBASHI KENICHI ET AL: "Molecular cloning of a novel form (two-repeat) protein related to voltage-gated sodium and calcium channels", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, ACADEMIC PRESS INC. ORLANDO, FL, US, vol. 270, no. 2, 13 April 2000 (2000-04-13), pages 370 - 376, XP002178968, ISSN: 0006-291X *

Also Published As

Publication number Publication date
WO2002052003A2 (en) 2002-07-04

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