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WO2002046382A3 - Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof - Google Patents

Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof Download PDF

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Publication number
WO2002046382A3
WO2002046382A3 PCT/US2001/046172 US0146172W WO0246382A3 WO 2002046382 A3 WO2002046382 A3 WO 2002046382A3 US 0146172 W US0146172 W US 0146172W WO 0246382 A3 WO0246382 A3 WO 0246382A3
Authority
WO
WIPO (PCT)
Prior art keywords
kinase proteins
human kinase
nucleic acid
acid molecules
molecules encoding
Prior art date
Application number
PCT/US2001/046172
Other languages
French (fr)
Other versions
WO2002046382A2 (en
Inventor
Ming-Hui Wei
Karl Guegler
Karen A Ketchum
Gennady V Merkulov
Francesco Valentina Di
Ellen M Beasley
Original Assignee
Pe Corp Ny
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/732,025 external-priority patent/US6416990B2/en
Priority claimed from US09/739,455 external-priority patent/US6413756B2/en
Application filed by Pe Corp Ny filed Critical Pe Corp Ny
Priority to CA002430624A priority Critical patent/CA2430624A1/en
Priority to EP01987246A priority patent/EP1414965A2/en
Priority to AU2002239483A priority patent/AU2002239483A1/en
Priority to JP2002548100A priority patent/JP2005500004A/en
Publication of WO2002046382A2 publication Critical patent/WO2002046382A2/en
Publication of WO2002046382A3 publication Critical patent/WO2002046382A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Pain & Pain Management (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the kinase peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the kinase peptides, and methods identifying modulators of the kinase peptides.
PCT/US2001/046172 2000-12-08 2001-12-06 Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof WO2002046382A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
CA002430624A CA2430624A1 (en) 2000-12-08 2001-12-06 Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof
EP01987246A EP1414965A2 (en) 2000-12-08 2001-12-06 Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof
AU2002239483A AU2002239483A1 (en) 2000-12-08 2001-12-06 Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof
JP2002548100A JP2005500004A (en) 2000-12-08 2001-12-06 Isolated human kinase protein, nucleic acid molecule encoding human kinase protein, and methods of use thereof

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US09/732,025 US6416990B2 (en) 2000-06-06 2000-12-08 Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof
US09/732,025 2000-12-08
US09/739,455 2000-12-19
US09/739,455 US6413756B2 (en) 2000-06-06 2000-12-19 Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof

Publications (2)

Publication Number Publication Date
WO2002046382A2 WO2002046382A2 (en) 2002-06-13
WO2002046382A3 true WO2002046382A3 (en) 2004-02-26

Family

ID=27112342

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/046172 WO2002046382A2 (en) 2000-12-08 2001-12-06 Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof

Country Status (5)

Country Link
EP (1) EP1414965A2 (en)
JP (1) JP2005500004A (en)
AU (1) AU2002239483A1 (en)
CA (1) CA2430624A1 (en)
WO (1) WO2002046382A2 (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000073469A2 (en) * 1999-05-28 2000-12-07 Sugen, Inc. Protein kinases

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000073469A2 (en) * 1999-05-28 2000-12-07 Sugen, Inc. Protein kinases

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
ABE M K ET AL: "EXTRACELLULAR SIGNAL-REGULATED KINASE 7 (ERK7), A NOVEL ERK WITH A C-TERMINAL DOMAIN THAT REGULATES ITS ACTIVITY, ITS CELLULAR LOCALIZATION, AND CELL GROWTH", MOLECULAR AND CELLULAR BIOLOGY, WASHINGTON, DC, US, vol. 19, no. 2, February 1999 (1999-02-01), pages 1301 - 1312, XP002172155, ISSN: 0270-7306 *
BARTON G J: "PROTEIN SEQUENCE ALIGMENT AND DATABASE SCANNING", PROTEIN STRUCTURE PREDICTION. A PRACTICAL APPROACH, XX, XX, 1996, pages 31 - 63, XP000829540 *
GEORGE D G ET AL: "CURRENT METHODS IN SEQUENCE COMPARISON AND ANALYSIS", MACROMOLECULAR SEQUENCING AND SYNTHESIS SELECTED METHODS AND APPLICATIONS, XX, XX, 1988, pages 127 - 149, XP000829541 *

Also Published As

Publication number Publication date
WO2002046382A2 (en) 2002-06-13
JP2005500004A (en) 2005-01-06
EP1414965A2 (en) 2004-05-06
AU2002239483A1 (en) 2002-06-18
CA2430624A1 (en) 2002-06-13

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