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WO2002046230A3 - Récepteurs couplés à la protéine g - Google Patents

Récepteurs couplés à la protéine g Download PDF

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Publication number
WO2002046230A3
WO2002046230A3 PCT/US2001/046659 US0146659W WO0246230A3 WO 2002046230 A3 WO2002046230 A3 WO 2002046230A3 US 0146659 W US0146659 W US 0146659W WO 0246230 A3 WO0246230 A3 WO 0246230A3
Authority
WO
WIPO (PCT)
Prior art keywords
protein coupled
coupled receptors
gcrec
provides
polynucleotides
Prior art date
Application number
PCT/US2001/046659
Other languages
English (en)
Other versions
WO2002046230A2 (fr
Inventor
Deborah A Kallick
Mariah R Baughn
Dyung Aina M Lu
Henry Yue
Richard C Graul
Yan Lu
Li Ding
Catherine M Tribouley
Y Tom Tang
Ameena R Gandhi
Michael Thornton
Original Assignee
Incyte Genomics Inc
Deborah A Kallick
Mariah R Baughn
Dyung Aina M Lu
Henry Yue
Richard C Graul
Yan Lu
Li Ding
Catherine M Tribouley
Y Tom Tang
Ameena R Gandhi
Michael Thornton
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Genomics Inc, Deborah A Kallick, Mariah R Baughn, Dyung Aina M Lu, Henry Yue, Richard C Graul, Yan Lu, Li Ding, Catherine M Tribouley, Y Tom Tang, Ameena R Gandhi, Michael Thornton filed Critical Incyte Genomics Inc
Priority to JP2002547966A priority Critical patent/JP2005501503A/ja
Priority to CA002430993A priority patent/CA2430993A1/fr
Priority to AU2002220231A priority patent/AU2002220231A1/en
Priority to EP01999578A priority patent/EP1339748A2/fr
Priority to US10/433,581 priority patent/US20040059092A1/en
Publication of WO2002046230A2 publication Critical patent/WO2002046230A2/fr
Publication of WO2002046230A3 publication Critical patent/WO2002046230A3/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C07K14/723—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH receptor
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Oncology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Virology (AREA)
  • Diabetes (AREA)
  • Communicable Diseases (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Endocrinology (AREA)
  • Peptides Or Proteins (AREA)

Abstract

L'invention concerne des récepteurs humains couplés à la protéine G (GCREC) et des polynucléotides qui identifient et codent pour CGREC. L'invention concerne également des vecteurs d'expression, des cellules hôtes, des anticorps, des agonistes et des antagonistes. L'invention concerne en outre des méthodes de diagnostic, de traitement ou de prévention de troubles associés à une expression aberrante de GCREC.
PCT/US2001/046659 2000-12-08 2001-12-05 Récepteurs couplés à la protéine g WO2002046230A2 (fr)

Priority Applications (5)

Application Number Priority Date Filing Date Title
JP2002547966A JP2005501503A (ja) 2000-12-08 2001-12-05 Ｇタンパク質共役受容体
CA002430993A CA2430993A1 (fr) 2000-12-08 2001-12-05 Recepteurs couples a la proteine g
AU2002220231A AU2002220231A1 (en) 2000-12-08 2001-12-05 G-protein coupled receptors
EP01999578A EP1339748A2 (fr) 2000-12-08 2001-12-05 Recepteurs couples a la proteine g
US10/433,581 US20040059092A1 (en) 2001-12-05 2001-12-05 G-protein coupled receptors

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US25432300P 2000-12-08 2000-12-08
US60/254,323 2000-12-08
US25556400P 2000-12-13 2000-12-13
US60/255,564 2000-12-13
US25771600P 2000-12-21 2000-12-21
US60/257,716 2000-12-21
US26284801P 2001-01-19 2001-01-19
US60/262,848 2001-01-19

Publications (2)

Publication Number Publication Date
WO2002046230A2 WO2002046230A2 (fr) 2002-06-13
WO2002046230A3 true WO2002046230A3 (fr) 2003-06-05

Family

ID=27500503

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/046659 WO2002046230A2 (fr) 2000-12-08 2001-12-05 Récepteurs couplés à la protéine g

Country Status (5)

Country Link
EP (1) EP1339748A2 (fr)
JP (1) JP2005501503A (fr)
AU (1) AU2002220231A1 (fr)
CA (1) CA2430993A1 (fr)
WO (1) WO2002046230A2 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7803982B2 (en) 2001-04-20 2010-09-28 The Mount Sinai School Of Medicine Of New York University T1R3 transgenic animals, cells and related methods
JP2004242644A (ja) * 2002-12-18 2004-09-02 National Institute Of Advanced Industrial & Technology グアノシン三リン酸結合タンパク質共役型の受容体

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000015793A2 (fr) * 1998-09-17 2000-03-23 Incyte Pharmaceuticals, Inc. Proteines gpcr humaines
WO2000020590A2 (fr) * 1998-10-06 2000-04-13 Incyte Pharmaceuticals, Inc. Proteines de recepteurs couples a des proteines g
WO2001087932A2 (fr) * 2000-05-12 2001-11-22 Lexicon Genetics Incorporated Sept protéines transmembranaires et polynucléotides les codant

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000015793A2 (fr) * 1998-09-17 2000-03-23 Incyte Pharmaceuticals, Inc. Proteines gpcr humaines
WO2000020590A2 (fr) * 1998-10-06 2000-04-13 Incyte Pharmaceuticals, Inc. Proteines de recepteurs couples a des proteines g
WO2001087932A2 (fr) * 2000-05-12 2001-11-22 Lexicon Genetics Incorporated Sept protéines transmembranaires et polynucléotides les codant

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
ABE J ET AL: "Ig-Hepta, a novel member of the G protein-coupled hepta-helical receptor (GPCR) family that has immunoglobulin-like repeats in a long N-terminal extracellular domain and defines a new subfamily of GPCRs", JOURNAL OF BIOLOGICAL CHEMISTRY, AMERICAN SOCIETY OF BIOLOGICAL CHEMISTS, BALTIMORE, MD, US, vol. 274, no. 28, 9 July 1999 (1999-07-09), pages 19957 - 19964, XP002182069, ISSN: 0021-9258 *
NATIONAL CANCER INSTITUTE ET AL: "aa27e08.r1 NCI_CGAP_GCB1 Homo sapiens cDNA clone IMAGE:814502 5', mRNA sequence", EMBL EST, XP002182071 *

Also Published As

Publication number Publication date
WO2002046230A2 (fr) 2002-06-13
JP2005501503A (ja) 2005-01-20
EP1339748A2 (fr) 2003-09-03
CA2430993A1 (fr) 2002-06-13
AU2002220231A1 (en) 2002-06-18

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