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WO2002040539A3 - Gpcr-like protein and nucleic acids encoding same - Google Patents

Gpcr-like protein and nucleic acids encoding same Download PDF

Info

Publication number
WO2002040539A3
WO2002040539A3 PCT/US2001/032256 US0132256W WO0240539A3 WO 2002040539 A3 WO2002040539 A3 WO 2002040539A3 US 0132256 W US0132256 W US 0132256W WO 0240539 A3 WO0240539 A3 WO 0240539A3
Authority
WO
WIPO (PCT)
Prior art keywords
nucleic acids
protein
gpcr
acids encoding
encoding same
Prior art date
Application number
PCT/US2001/032256
Other languages
French (fr)
Other versions
WO2002040539A2 (en
Original Assignee
Curagen Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to AU3923502A priority Critical patent/AU3923502A/en
Application filed by Curagen Corp filed Critical Curagen Corp
Priority to AU2002239235A priority patent/AU2002239235A1/en
Publication of WO2002040539A2 publication Critical patent/WO2002040539A2/en
Publication of WO2002040539A3 publication Critical patent/WO2002040539A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Disclosed herein are nucleic acid sequences that encode G-coupled protein-receptor related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.
PCT/US2001/032256 2000-10-16 2001-10-16 Gpcr-like protein and nucleic acids encoding same WO2002040539A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU3923502A AU3923502A (en) 2000-10-16 2001-10-11 Novel gpcr-like protein and nucleic acids encoding same
AU2002239235A AU2002239235A1 (en) 2000-10-16 2001-10-16 Gpcr-like protein and nucleic acids encoding same

Applications Claiming Priority (24)

Application Number Priority Date Filing Date Title
US24070400P 2000-10-16 2000-10-16
US60/240,704 2000-10-16
US24349700P 2000-10-26 2000-10-26
US60/243,497 2000-10-26
US24454200P 2000-10-31 2000-10-31
US60/244,542 2000-10-31
US24548400P 2000-11-03 2000-11-03
US60/245,484 2000-11-03
US25501700P 2000-12-12 2000-12-12
US60/255,017 2000-12-12
US26215901P 2001-01-17 2001-01-17
US60/262,159 2001-01-17
US26321601P 2001-01-22 2001-01-22
US26334001P 2001-01-22 2001-01-22
US60/263,216 2001-01-22
US60/263,340 2001-01-22
US26411801P 2001-01-25 2001-01-25
US60/264,118 2001-01-25
US26822501P 2001-02-12 2001-02-12
US60/268,225 2001-02-12
US28903101P 2001-02-15 2001-02-15
US60/289,031 2001-02-15
US30820301P 2001-07-27 2001-07-27
US60/308,203 2001-07-27

Publications (2)

Publication Number Publication Date
WO2002040539A2 WO2002040539A2 (en) 2002-05-23
WO2002040539A3 true WO2002040539A3 (en) 2003-08-28

Family

ID=27583815

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/032256 WO2002040539A2 (en) 2000-10-16 2001-10-16 Gpcr-like protein and nucleic acids encoding same

Country Status (2)

Country Link
AU (2) AU3923502A (en)
WO (1) WO2002040539A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8883714B2 (en) 2008-04-07 2014-11-11 Arena Pharmaceuticals, Inc. Pharmaceutical compositions comprising GPR119 agonists which act as peptide YY (PYY) secretagogues

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002357322A1 (en) 2001-12-19 2003-07-09 The University Of Chicago Rapidly maturing fluorescent proteins and methods for using the same
JP4755174B2 (en) 2004-04-07 2011-08-24 ザ ユニヴァーシティー オヴ シカゴ Monomeric red fluorescent protein
US8679749B2 (en) 2007-11-01 2014-03-25 The University Of Chicago Red fluorescent proteins with enhanced bacterial expression, increased brightness and reduced aggregation

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001027158A2 (en) * 1999-10-08 2001-04-19 Digiscents Olfactory receptor sequences
WO2001057215A2 (en) * 2000-02-07 2001-08-09 Curagen Corporation Human g-protein coupled receptor polypeptides and polynucleotides having homology with odorant receptors
WO2001059117A2 (en) * 2000-02-11 2001-08-16 Millennium Pharmaceuticals, Inc. Seven-transmembrane proteins/g-protein coupled receptors
WO2001068805A2 (en) * 2000-03-13 2001-09-20 Senomyx, Inc. Human olfactory receptors and genes encoding same

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001027158A2 (en) * 1999-10-08 2001-04-19 Digiscents Olfactory receptor sequences
WO2001057215A2 (en) * 2000-02-07 2001-08-09 Curagen Corporation Human g-protein coupled receptor polypeptides and polynucleotides having homology with odorant receptors
WO2001059117A2 (en) * 2000-02-11 2001-08-16 Millennium Pharmaceuticals, Inc. Seven-transmembrane proteins/g-protein coupled receptors
WO2001068805A2 (en) * 2000-03-13 2001-09-20 Senomyx, Inc. Human olfactory receptors and genes encoding same

Non-Patent Citations (14)

* Cited by examiner, † Cited by third party
Title
BUCK L ET AL: "A NOVEL MULTIGENE FAMILY MAY ENCODE ODORANT RECEPTORS: A MOLECULAR BASIS FOR ODOR RECOGNITION", CELL, CELL PRESS, CAMBRIDGE, NA, US, vol. 65, 5 April 1991 (1991-04-05), pages 175 - 187, XP002029935, ISSN: 0092-8674 *
BUETTNER J A ET AL: "Organization and evolution of olfactory receptor genes on human chromosome 11", GENOMICS, ACADEMIC PRESS, SAN DIEGO, US, vol. 53, no. GE985422, 1 October 1998 (1998-10-01), pages 56 - 68, XP002135640, ISSN: 0888-7543 *
DATABASE EMBL [online] 18 December 2001 (2001-12-18), ZOZULYA, retrieved from EBI Database accession no. AAU24672 *
DATABASE EMBL [online] 30 July 2001 (2001-07-30), BELLENSON ET AL., retrieved from EBI Database accession no. AAG71691 *
DATABASE EMBL [online] 6 September 2001 (2001-09-06), GLUCKSMANN ET AL., retrieved from EBI Database accession no. AX213272 *
DATABASE EMBL 11 December 1998 (1998-12-11), KRAUTWURST ET AL. *
GLUSMAN G ET AL: "SEQUENCE ANALYSIS IN THE OLFACTORY RECEPTOR GENE CLUSTER ON HUMAN CHROMOSOME 17: RECOMBINATORIAL EVENTS AFFECTING RECEPTOR DIVERSITY", GENOMICS, ACADEMIC PRESS, SAN DIEGO, US, vol. 37, no. 2, 1996, pages 147 - 160, XP000886076, ISSN: 0888-7543 *
GLUSMAN GUSTAVO ET AL: "Sequence, structure, and evolution of a complete human olfactory receptor gene cluster", GENOMICS, ACADEMIC PRESS, SAN DIEGO, US, vol. 63, no. 2, 15 January 2000 (2000-01-15), pages 227 - 245, XP002178957, ISSN: 0888-7543 *
KRAUTWURST D ET AL: "Identification of ligands for olfactory receptors by functional expression of a receptor library", CELL, CELL PRESS, CAMBRIDGE, NA, US, vol. 95, AF102523, 25 June 1998 (1998-06-25), pages 917 - 926, XP002153217, ISSN: 0092-8674, Retrieved from the Internet <URL:EBI> *
MALNIC BETTINA ET AL: "Combinatorial receptor codes for odors", CELL, CELL PRESS, CAMBRIDGE, NA, US, vol. 96, no. 5, 5 March 1999 (1999-03-05), pages 713 - 723, XP002188611, ISSN: 0092-8674 *
ROUQUIER S ET AL: "A GENE RECENTLY INACTIVATED IN HUMAN DEFINES A NEW OLFACTORY RECEPTOR FAMILY IN MAMMALS", HUMAN MOLECULAR GENETICS, OXFORD UNIVERSITY PRESS, SURREY, GB, vol. 7, no. 9, September 1998 (1998-09-01), pages 1337 - 1345, XP000974297, ISSN: 0964-6906 *
STERNBERG M J E ET AL: "LOCAL PROTEIN SEQUENCE SIMILARITY DOES NOT IMPLY A STRUCTURAL RELATIONSHIP", PROTEIN ENGINEERING, OXFORD UNIVERSITY PRESS, SURREY, GB, vol. 4, no. 2, December 1990 (1990-12-01), pages 125 - 131, XP001068574, ISSN: 0269-2139 *
TRASK B J ET AL: "Members of the olfactory receptor gene family are contained in large blocks of DNA duplicated polymorphically near the ends of human chromosomes", HUMAN MOLECULAR GENETICS, OXFORD UNIVERSITY PRESS, SURREY, GB, vol. 7, no. 1, January 1998 (1998-01-01), pages 13 - 26, XP002135641, ISSN: 0964-6906 *
WETZEL CHRISTIAN H ET AL: "Specificity and sensitivity of a human olfactory receptor functionally expressed in human embryonic kidney 293 cells and Xenopus laevis oocytes", JOURNAL OF NEUROSCIENCE, NEW YORK, NY, US, vol. 19, no. 17, 1 September 1999 (1999-09-01), pages 7426 - 7433, XP002178954, ISSN: 0270-6474 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8883714B2 (en) 2008-04-07 2014-11-11 Arena Pharmaceuticals, Inc. Pharmaceutical compositions comprising GPR119 agonists which act as peptide YY (PYY) secretagogues

Also Published As

Publication number Publication date
WO2002040539A2 (en) 2002-05-23
AU2002239235A1 (en) 2002-05-27
AU3923502A (en) 2002-05-27

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