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WO2001038846A1 - Sampling device - Google Patents

Sampling device Download PDF

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Publication number
WO2001038846A1
WO2001038846A1 PCT/GB2000/004521 GB0004521W WO0138846A1 WO 2001038846 A1 WO2001038846 A1 WO 2001038846A1 GB 0004521 W GB0004521 W GB 0004521W WO 0138846 A1 WO0138846 A1 WO 0138846A1
Authority
WO
WIPO (PCT)
Prior art keywords
barrel
plunger
sampling device
filter
liquid
Prior art date
Application number
PCT/GB2000/004521
Other languages
French (fr)
Inventor
Martin Reilly
Nerys Bennion
Original Assignee
Biotrace Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biotrace Limited filed Critical Biotrace Limited
Priority to AU17151/01A priority Critical patent/AU1715101A/en
Publication of WO2001038846A1 publication Critical patent/WO2001038846A1/en

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/021—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids
    • B01L3/0217—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids of the plunger pump type
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/02—Devices for withdrawing samples
    • G01N1/10—Devices for withdrawing samples in the liquid or fluent state
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/02—Food
    • G01N33/14—Beverages

Definitions

  • the present invention relates to a sampling device, particularly but not solely to a sampling device for carrying out a hygiene test using ATP-biolummescence .
  • a sampling device which enables beer or other liquid to be tested for the presence of bacteria or other micro-organisms particularly where such beer or other liquid is delivered through a dispensing system.
  • a sampling device which comprises a plunger longitudinally displaceable m a barrel, the plunger being displaceable m one direction to draw a volume of liquid into the barrel, then being displaceable m the opposite direction to expel the volume of liquid through a filter and also to expel a volume of a reagent through the filter.
  • the expelled liquid may be collected m a vessel where it is further processed or tested
  • the reagent may comprise an ATP release reagent, which serves to release ATP from the microbial cells m passing through the filter: the expelled liquid, collected m the collection vessel, is then mixed with the enzyme luciferase, to react with the ATP and cause luminescence: the vessel may then be inserted into a photometer or lummometer, to measure the degree of luminescence.
  • the device is arranged so that the reagent is expelled through the filter only during a final portion of travel of the plunger m the expelling direction.
  • the reagent is contained m a compartment of the plunger, which is normally sealed by an impermeable membrane arranged to be ruptured at a predetermined point m the plunger's travel.
  • the barrel is formed w th a projection which cooperates with the plunger to rupture the membrane when the plunger reaches the predetermined point m its travel.
  • the device includes a one-way valve through which the sample of liquid is drawn into the barrel.
  • the device includes a nozzle through which the sample of liquid is drawn into the barrel, and through which the liquid is subsequently expelled.
  • the one-way valve and the filter are provided m respective compartments positioned at the lower end of the barrel.
  • these compartments are defined between the outer bottom surface of the barrel and a generally disc-shaped member secured to the bottom of the barrel.
  • the plunger is screw-threadedly engaged to the barrel, such that the plunger is displaced longitudinally of the barrel by turning the plunger relative to the barrel . This arrangement ensures that the longitudinal displacement of the plunger will be gradual, and so minimise the risk of the beer or other liquid foaming as it is drawn into or expelled from the barrel .
  • the plunger is formed with a helical formation on its outer surface, for co-operating with a projection provided adjacent the upper end of the barrel, to provide the screw-threaded engagement between the plunger and the barrel .
  • a sampling device which comprises a plunger longitudinally displaceable in a barrel by turning the plunger relative to the barrel .
  • a sampling device which comprises a plunger longitudinally displaceable in a barrel, the plunger being formed with a compartment which contains a reagent and is arranged to release the reagent when the plunger reaches a predetermined point m its travel relative to the barrel.
  • a sampling device which comprises a plunger longitudinally displaceable in a barrel, the barrel being provided with a one-way valve for inlet of fluid into the barrel and a filter through which fluid may be expelled from the barrel, the one-way valve and filter being disposed side- by-side at the lower end of the barrel.
  • FIGURE 1 is a side view of a sampling device in accordance with the present invention
  • FIGURE 2 is a view of the device in the direction of arrow A shown in Figure 1 ;
  • FIGURE 3 is a section through the device on the line III -III shown in Figure 2;
  • FIGURE 4 is a section through a cuvette with which the device of Figures 1 to 3 is used.
  • the device comprises a plunger 10 displaceable in a cylindrical generally cup- shaped barrel 20, from which a nozzle 30 extends.
  • the plunger 10 is hollow and formed with an open upper end 11 of an enlarged diameter: the outer surface of the plunger 10 is formed with a helical rib 12 which co-operates with a projection (not shown) provided on the inner surface of a collar 22 which is ultrasonically welded to the upper end of the barrel 20; the arrangement is such that the plunger 10 may be displaced longitudinally within the barrel 20 by turning the plunger relative to the barrel.
  • An 0-r ⁇ ng seal 13 is carried in a peripheral groove formed in the outer surface of the plunger 10, adjacent its lower end, to maintain a seal between the plunger and the barrel as the plunger is displaced.
  • the plunger 10 is formed with a cylindrical recess 14, providing a compartment which is filled with an ATP-release reagent and is closed by a foil membrane 15.
  • a projection is formed at the centre of the bottom of the barrel 20, comprising an upstanding tubular section 21 which receives a cap 23 as a push-fit: this projection is arranged to rupture the membrane 15 as the plunger 10 is displaced almost fully into the barrel 20, so releasing the liquid from the compartment 14.
  • a generally disc-shaped housing member 24 is carried on the outer bottom side of the barrel 20, the member 24 having a rim 25 by which it is ultrasonically welded to the barrel.
  • the member 24 and the bottom surface of the barrel 20 cooperate to define two generally circular, planar compartments 26, 28 respectively housing a flat valve seal 27 and a filter membrane 29.
  • the two compartments 26, 28 each communicate with the interior of the barrel 20 and also with a transverse passage 31 m the top end of the nozzle 30: the passage 31 m turn communicates with a longitudinal passage 32 of the nozzle.
  • valve and filter are conveniently positioned side-by-side and formed m a common structure .
  • the nozzle 30 of the device is dipped into a volume of beer or other liquid which has been dispensed from a system to be tested.
  • the plunger 10 is then turned by hand m order to displace it longitudinally, m the retracting direction, relative to the barrel 20: a corresponding volume of the beer or other liquid is accordingly drawn through the nozzle 30 and into the barrel 20, via the valve compartment 26.
  • the plunger 10 is displaced m the opposite direction, into the barrel 20, to expel the sample of beer or other liquid from the barrel:
  • the valve 26, 27 is a one-way valve which prevents the liquid being expelled through it, and instead the liquid is expelled through the filter 29. If the sample of liquid includes bacteria cells, these are captured on the filter 29.
  • the foil membrane 15 of its reagent compartment 14 makes contact with the projection 21,23 on the inside bottom of the barrel 20, and is ruptured, so releasing the reagent.
  • the reagent is expelled, together with the final volume of the beer or other sample liquid, through the nozzle 30 via the filter 29.
  • the reagent which is then passed through the filter serves to release ATP from those cells.
  • the liquid expelled from the device is now mixed with a solution of the enzyme luciferase, m order to promote a reaction with any ATP which has been released, and so cause luminescence.
  • a transparent vessel or cuvette 40 as shown m Figure 4 is used: the cuvette 40 includes a cylindrical compartment 42 which is sealed across its top and bottom by foil membranes 41,43, the compartment containing the enzyme solution.
  • the nozzle 30 of the device Prior to expelling the final volume of sample , and the reagent, from the device, the nozzle 30 of the device is introduced into the cuvette to pierce and rupture the membranes 41,43: the final volume of sample liquid and the reagent are then expelled from the device and into the cuvette 40, for mixing with the enzyme solution. Then the nozzle of the device is removed from the cuvette and one end of a rod is inserted into the top of the cuvette, as an interference fit: the rod provides a convenient handling means for positioning the cuvette 40 m a lummometer, for the measurement of the photon emission.
  • this device which has been described enables beer or other liquid to be tested on-site m an easy and quick manner, to provide a hygiene test m relation to the delivery system through which the beer or other liquid is dispensed.
  • the device may be used m relation to a wide variety of liquids, including all filterable beverages (e.g. water, soft drinks, juices) and other filterable liquids, where the detection of micro-organisms may be desired, e.g. process, cooling and rinse water m food, beverage, pharmaceutical and industrial processes, or for water in the flower industry (where poor quality water is known the curtail the life of cut flowers) .
  • the device which has been described may be used to test for the presence of bacteria or other microbial sources of ATP, including but not limited to yeast, mould, algae and microbial biofllm made up of such organisms embedded m complex carbohydrate structures.
  • bacteria or other microbial sources of ATP including but not limited to yeast, mould, algae and microbial biofllm made up of such organisms embedded m complex carbohydrate structures.
  • the device may be used with other reagent systems.

Landscapes

  • Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

A sampling device comprises a plunger (10) longitudinally displaceable in one direction in a barrel (20) to draw a volume of liquid into the barrel, and then displaceable in the opposite direction to expel the volume of liquid, and also a volume of reagent contained in a compartment (14) of the plunger, through a filter (29). The device may be used to test for the presence of micro-organisms picked up by the liquid being sampled, which are captured by the filter upon expelling the sample from the device.

Description

Sampling device
The present invention relates to a sampling device, particularly but not solely to a sampling device for carrying out a hygiene test using ATP-biolummescence .
In systems for dispensing beer or other liquids, it is possible for bacteria or other micro-organisms to accumulate m the conduits through which the liquid is dispensed, despite carrying out periodic cleaning. This has been known for many years to cause quality problems m the brewing industry but no convenient method has been developed to measure the extent of the problem or to overcome it .
We have now devised a sampling device which enables beer or other liquid to be tested for the presence of bacteria or other micro-organisms particularly where such beer or other liquid is delivered through a dispensing system. In accordance with the present invention, there is provided a sampling device which comprises a plunger longitudinally displaceable m a barrel, the plunger being displaceable m one direction to draw a volume of liquid into the barrel, then being displaceable m the opposite direction to expel the volume of liquid through a filter and also to expel a volume of a reagent through the filter.
It will be appreciated that, if the sample of liquid (e.g. beer) is contaminated with microbial cells, picked up from the dispensing system or otherwise, then these cells will be captured by the filter. Then by passing the reagent through the filter, this will serve to react with the microbial cells so that the presence of such cells may be indicated. The expelled liquid may be collected m a vessel where it is further processed or tested For example, the reagent may comprise an ATP release reagent, which serves to release ATP from the microbial cells m passing through the filter: the expelled liquid, collected m the collection vessel, is then mixed with the enzyme luciferase, to react with the ATP and cause luminescence: the vessel may then be inserted into a photometer or lummometer, to measure the degree of luminescence.
Preferably the device is arranged so that the reagent is expelled through the filter only during a final portion of travel of the plunger m the expelling direction. Preferably the reagent is contained m a compartment of the plunger, which is normally sealed by an impermeable membrane arranged to be ruptured at a predetermined point m the plunger's travel. Preferably the barrel is formed w th a projection which cooperates with the plunger to rupture the membrane when the plunger reaches the predetermined point m its travel. Preferably the device includes a one-way valve through which the sample of liquid is drawn into the barrel.
Preferably the device includes a nozzle through which the sample of liquid is drawn into the barrel, and through which the liquid is subsequently expelled. Preferably the one-way valve and the filter are provided m respective compartments positioned at the lower end of the barrel. Preferably these compartments are defined between the outer bottom surface of the barrel and a generally disc-shaped member secured to the bottom of the barrel. Preferably the plunger is screw-threadedly engaged to the barrel, such that the plunger is displaced longitudinally of the barrel by turning the plunger relative to the barrel . This arrangement ensures that the longitudinal displacement of the plunger will be gradual, and so minimise the risk of the beer or other liquid foaming as it is drawn into or expelled from the barrel . Preferably the plunger is formed with a helical formation on its outer surface, for co-operating with a projection provided adjacent the upper end of the barrel, to provide the screw-threaded engagement between the plunger and the barrel .
Also in accordance with the present invention, there is provided a sampling device which comprises a plunger longitudinally displaceable in a barrel by turning the plunger relative to the barrel .
Further in accordance with the present invention, there is provided a sampling device which comprises a plunger longitudinally displaceable in a barrel, the plunger being formed with a compartment which contains a reagent and is arranged to release the reagent when the plunger reaches a predetermined point m its travel relative to the barrel.
Yet further in accordance with the present invention, there is provided a sampling device which comprises a plunger longitudinally displaceable in a barrel, the barrel being provided with a one-way valve for inlet of fluid into the barrel and a filter through which fluid may be expelled from the barrel, the one-way valve and filter being disposed side- by-side at the lower end of the barrel. An embodiment of the present invention will now be described by way of example only and with reference to the accompanying drawings, m which:
FIGURE 1 is a side view of a sampling device in accordance with the present invention; FIGURE 2 is a view of the device in the direction of arrow A shown in Figure 1 ;
FIGURE 3 is a section through the device on the line III -III shown in Figure 2; and
FIGURE 4 is a section through a cuvette with which the device of Figures 1 to 3 is used.
Referring to the drawings, there is shown a disposable sampling device assembled from components of plastics material. The device comprises a plunger 10 displaceable in a cylindrical generally cup- shaped barrel 20, from which a nozzle 30 extends. The plunger 10 is hollow and formed with an open upper end 11 of an enlarged diameter: the outer surface of the plunger 10 is formed with a helical rib 12 which co-operates with a projection (not shown) provided on the inner surface of a collar 22 which is ultrasonically welded to the upper end of the barrel 20; the arrangement is such that the plunger 10 may be displaced longitudinally within the barrel 20 by turning the plunger relative to the barrel. An 0-rιng seal 13 is carried in a peripheral groove formed in the outer surface of the plunger 10, adjacent its lower end, to maintain a seal between the plunger and the barrel as the plunger is displaced.
In the centre of its lower end, the plunger 10 is formed with a cylindrical recess 14, providing a compartment which is filled with an ATP-release reagent and is closed by a foil membrane 15. A projection is formed at the centre of the bottom of the barrel 20, comprising an upstanding tubular section 21 which receives a cap 23 as a push-fit: this projection is arranged to rupture the membrane 15 as the plunger 10 is displaced almost fully into the barrel 20, so releasing the liquid from the compartment 14.
A generally disc-shaped housing member 24 is carried on the outer bottom side of the barrel 20, the member 24 having a rim 25 by which it is ultrasonically welded to the barrel. The member 24 and the bottom surface of the barrel 20 cooperate to define two generally circular, planar compartments 26, 28 respectively housing a flat valve seal 27 and a filter membrane 29. The two compartments 26, 28 each communicate with the interior of the barrel 20 and also with a transverse passage 31 m the top end of the nozzle 30: the passage 31 m turn communicates with a longitudinal passage 32 of the nozzle.
It will be noted that the valve and filter are conveniently positioned side-by-side and formed m a common structure .
In use, the nozzle 30 of the device is dipped into a volume of beer or other liquid which has been dispensed from a system to be tested. The plunger 10 is then turned by hand m order to displace it longitudinally, m the retracting direction, relative to the barrel 20: a corresponding volume of the beer or other liquid is accordingly drawn through the nozzle 30 and into the barrel 20, via the valve compartment 26.
Next the plunger 10 is displaced m the opposite direction, into the barrel 20, to expel the sample of beer or other liquid from the barrel: the valve 26, 27 is a one-way valve which prevents the liquid being expelled through it, and instead the liquid is expelled through the filter 29. If the sample of liquid includes bacteria cells, these are captured on the filter 29.
Towards the end of the plunger's travel, the foil membrane 15 of its reagent compartment 14 makes contact with the projection 21,23 on the inside bottom of the barrel 20, and is ruptured, so releasing the reagent. During the final travel of the plunger 10, the reagent is expelled, together with the final volume of the beer or other sample liquid, through the nozzle 30 via the filter 29.
In the event of bacteria cells being captured on the filter 29, the reagent which is then passed through the filter serves to release ATP from those cells. The liquid expelled from the device is now mixed with a solution of the enzyme luciferase, m order to promote a reaction with any ATP which has been released, and so cause luminescence. For this purpose, a transparent vessel or cuvette 40 as shown m Figure 4 is used: the cuvette 40 includes a cylindrical compartment 42 which is sealed across its top and bottom by foil membranes 41,43, the compartment containing the enzyme solution. Prior to expelling the final volume of sample , and the reagent, from the device, the nozzle 30 of the device is introduced into the cuvette to pierce and rupture the membranes 41,43: the final volume of sample liquid and the reagent are then expelled from the device and into the cuvette 40, for mixing with the enzyme solution. Then the nozzle of the device is removed from the cuvette and one end of a rod is inserted into the top of the cuvette, as an interference fit: the rod provides a convenient handling means for positioning the cuvette 40 m a lummometer, for the measurement of the photon emission.
It will be appreciated that this device which has been described enables beer or other liquid to be tested on-site m an easy and quick manner, to provide a hygiene test m relation to the delivery system through which the beer or other liquid is dispensed. The device may be used m relation to a wide variety of liquids, including all filterable beverages (e.g. water, soft drinks, juices) and other filterable liquids, where the detection of micro-organisms may be desired, e.g. process, cooling and rinse water m food, beverage, pharmaceutical and industrial processes, or for water in the flower industry (where poor quality water is known the curtail the life of cut flowers) . The device which has been described may be used to test for the presence of bacteria or other microbial sources of ATP, including but not limited to yeast, mould, algae and microbial biofllm made up of such organisms embedded m complex carbohydrate structures. However, it will be appreciated that the device may be used with other reagent systems.

Claims

Claims
1) A sampling device which comprises a plunger longitudinally displaceable m a barrel, the plunger being displaceable m one direction to draw a volume of liquid into the barrel, the plunger then being displaceable m the opposition direction to expel the volume of liquid through a filter and also to expel a volume of a reagent through the filter.
2) A sampling device as claimed m claim 1, arranged so that said reagent is expelled through said filter only during a final position of travel of said plunger m said opposite direction.
3) A sampling device as claimed m claim 2, m which said reagent is contained m a compartment of said plunger.
4) A sampling device as claimed in claim 3, in which said compartment is normally sealed by an impermeable membrane arranged to be ruptured at a predetermined point m the travel of said plunger m said opposite direction.
5) A sampling device as claimed m claim 4, m which said barrel is formed with a projection which co-operates with said plunger to rupture said membrane when said plunger reaches said predetermined point of travel .
6) A sampling device as claimed in any preceding claim, including a one-way valve through which said volume of liquid is drawn into said barrel .
7) A sampling device as claimed m claim 6, m which said one-way valve and filter are provided m respective compartments positioned at a lower end of said barrel.
8) A sampling device as claimed in claim 7, in which said one-way valve and filter compartments are formed between the outer surface of the barrel, at said lower end thereof, and a
5 member secured to said lower end of the barrel .
9) A sampling device as claimed in any preceding claim, further comprising a nozzle through which, in use, said volume of liquid is drawn into said barrel, and through which said volume of liquid is subsequently expelled.
10 10) A sampling device as claimed in any preceding claim, in which said plunger is screw-threadedly engaged to said barrel, such that said plunger is displaceable longitudinally of said barrel by turning said plunger relative to said barrel.
11) A sampling device as claimed in claim 10, in which said 15 plunger is formed with a helical formation on its outer surface, co-operating with a projection provided adjacent an upper end of said barrel .
12) A sampling device which comprises a plunger longitudinally displaceable in a barrel by turning said plunger 0 relative to said barrel .
13) A sampling device which comprises a plunger longitudinally displaceable in a barrel, said plunger being formed with a compartment which contains a reagent and is arranged to release said reagent when said plunger reaches a 5 predetermined point in its travel relative to said barrel.
14) A sampling device which comprises a plunger longitudinally displaceable in a barrel, said barrel being provided with a one-way valve for inlet of fluid into said barrel and a filter through which fluid may be expelled from said barrel, said one-way valve and filter being disposed side- by-side at a lower end of said barrel.
PCT/GB2000/004521 1999-11-25 2000-11-27 Sampling device WO2001038846A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU17151/01A AU1715101A (en) 1999-11-25 2000-11-27 Sampling device

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9927836A GB2356702A (en) 1999-11-25 1999-11-25 Liquid sampling device
GB9927836.8 1999-11-25

Publications (1)

Publication Number Publication Date
WO2001038846A1 true WO2001038846A1 (en) 2001-05-31

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ID=10865101

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2000/004521 WO2001038846A1 (en) 1999-11-25 2000-11-27 Sampling device

Country Status (3)

Country Link
AU (1) AU1715101A (en)
GB (1) GB2356702A (en)
WO (1) WO2001038846A1 (en)

Cited By (4)

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Publication number Priority date Publication date Assignee Title
US6924498B2 (en) 2002-04-24 2005-08-02 Biocontrol Systems, Inc. Sample collection and testing system
US7030403B2 (en) 2001-12-06 2006-04-18 Biocontrol Systems, Inc. Sample collection and bioluminescent sample testing system
US9446406B2 (en) 2012-06-29 2016-09-20 Biocontrol Systems, Inc. Sample collection and bioluminescent analysis system
CN114858526A (en) * 2022-03-22 2022-08-05 贵州大学 A kind of ginger and ginger blast pathogen detection and sampling equipment

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GB0222160D0 (en) * 2002-09-24 2002-10-30 Cybersense Biosystems Ltd Soil sampling and extraction unit

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CA2214233A1 (en) * 1997-08-29 1999-02-28 Eng-Hong Lee Method for assessing viability of live microbial therapeutic agents
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US4960130A (en) * 1989-01-10 1990-10-02 Cancer Diagnostics, Inc. Modular fluid sample preparation assembly
EP0509158A1 (en) * 1991-04-10 1992-10-21 La Mina Ltd. Method of testing for urine antigen
US5431884A (en) * 1994-02-22 1995-07-11 Sage Products, Inc. Specimen transporting and processing system
US5919356A (en) * 1994-12-24 1999-07-06 Fsm Technologies Ltd. Fluid sampling device
JPH1084941A (en) * 1996-09-18 1998-04-07 Kirin Brewery Co Ltd Sampling device for content in beer barrel and sampling method therefor
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Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7030403B2 (en) 2001-12-06 2006-04-18 Biocontrol Systems, Inc. Sample collection and bioluminescent sample testing system
US7399984B2 (en) 2001-12-06 2008-07-15 Biocontrol Systems Inc. Sample collection and testing system having a displacement member causing reagent to come into contact with a sample collection surface
US7544961B2 (en) 2001-12-06 2009-06-09 Biocontrol Systems, Inc. Sample collection and testing system including a rotatable shaft with a helical guiding member to translate longitudinal motion of a slidable shaft into rotational motion
US6924498B2 (en) 2002-04-24 2005-08-02 Biocontrol Systems, Inc. Sample collection and testing system
US9446406B2 (en) 2012-06-29 2016-09-20 Biocontrol Systems, Inc. Sample collection and bioluminescent analysis system
US10684232B2 (en) 2012-06-29 2020-06-16 Biocontrol Systems, Inc. Sample collection and bioluminescent analysis system
CN114858526A (en) * 2022-03-22 2022-08-05 贵州大学 A kind of ginger and ginger blast pathogen detection and sampling equipment

Also Published As

Publication number Publication date
AU1715101A (en) 2001-06-04
GB9927836D0 (en) 2000-01-26
GB2356702A (en) 2001-05-30

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