+

WO2001036644A3 - Wnt-regulated cytokine-like polypeptide and nucleic acids encoding same - Google Patents

Wnt-regulated cytokine-like polypeptide and nucleic acids encoding same Download PDF

Info

Publication number
WO2001036644A3
WO2001036644A3 PCT/US2000/031629 US0031629W WO0136644A3 WO 2001036644 A3 WO2001036644 A3 WO 2001036644A3 US 0031629 W US0031629 W US 0031629W WO 0136644 A3 WO0136644 A3 WO 0136644A3
Authority
WO
WIPO (PCT)
Prior art keywords
polypeptide
fctrx
wnt
nucleic acids
acids encoding
Prior art date
Application number
PCT/US2000/031629
Other languages
French (fr)
Other versions
WO2001036644A2 (en
Inventor
Luca Rastelli
David Lewin
Bruce Taillon
David P Andrew
Original Assignee
Curagen Corp
Luca Rastelli
David Lewin
Bruce Taillon
David P Andrew
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Curagen Corp, Luca Rastelli, David Lewin, Bruce Taillon, David P Andrew filed Critical Curagen Corp
Priority to AU16194/01A priority Critical patent/AU784859B2/en
Priority to CA002391380A priority patent/CA2391380A1/en
Priority to EP00978769A priority patent/EP1230370A2/en
Publication of WO2001036644A2 publication Critical patent/WO2001036644A2/en
Publication of WO2001036644A3 publication Critical patent/WO2001036644A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

The present invention provides novel polypeptides, termed FCTRX polypeptides, as well as polynucleotides encoding FCTRX polypeptides and antibodies that immunospecifically bind to an FCTRX or a derivative, variant, mutant, or fragment of an FCTRX polypeptide, polynucleotide or antibody. The invention additionally provides methods in which the FCTRX polypeptide, polynucleotide and antibody are used in detection and treatment of a broad range of pathological states, as well as to other uses.
PCT/US2000/031629 1999-11-18 2000-11-17 Wnt-regulated cytokine-like polypeptide and nucleic acids encoding same WO2001036644A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
AU16194/01A AU784859B2 (en) 1999-11-18 2000-11-17 WNT-regulated cytokine-like polypeptide and nucleic acids encoding same
CA002391380A CA2391380A1 (en) 1999-11-18 2000-11-17 Wnt-regulated cytokine-like polypeptide and nucleic acids encoding same
EP00978769A EP1230370A2 (en) 1999-11-18 2000-11-17 Wnt-regulated cytokine-like polypeptide and nucleic acids encoding same

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16617799P 1999-11-18 1999-11-18
US60/166,177 1999-11-18

Publications (2)

Publication Number Publication Date
WO2001036644A2 WO2001036644A2 (en) 2001-05-25
WO2001036644A3 true WO2001036644A3 (en) 2001-11-29

Family

ID=22602126

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/031629 WO2001036644A2 (en) 1999-11-18 2000-11-17 Wnt-regulated cytokine-like polypeptide and nucleic acids encoding same

Country Status (2)

Country Link
EP (1) EP1230370A2 (en)
WO (1) WO2001036644A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002248201A1 (en) * 2000-11-16 2002-08-06 Curagen Corporation Growth factor polypeptides and nucleic acids encoding same
AT412026B (en) * 2002-02-07 2004-08-26 Illmensee Karl Dr METHOD FOR DIAGNOSING A CYSTIC OVARIAL CARCINOMA
DE10361444A1 (en) * 2003-12-23 2005-07-21 Axaron Bioscience Ag Method for in vitro differentiation of neuronal stem cells or cells derived from neuronal stem cells

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997034013A1 (en) * 1996-03-11 1997-09-18 Human Genome Sciences, Inc. Chemotactic cytokine ii
WO1999047669A2 (en) * 1998-03-20 1999-09-23 Metagen Gesellschaft Für Genomforschung Mbh Human nucleic acid sequences from tissue of breast tumors
WO2001000828A2 (en) * 1999-06-30 2001-01-04 Corixa Corporation Compositions and methods for the therapy and diagnosis of lung cancer

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997034013A1 (en) * 1996-03-11 1997-09-18 Human Genome Sciences, Inc. Chemotactic cytokine ii
WO1999047669A2 (en) * 1998-03-20 1999-09-23 Metagen Gesellschaft Für Genomforschung Mbh Human nucleic acid sequences from tissue of breast tumors
WO2001000828A2 (en) * 1999-06-30 2001-01-04 Corixa Corporation Compositions and methods for the therapy and diagnosis of lung cancer

Non-Patent Citations (8)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL 16 May 1997 (1997-05-16), M.M MARRA ET AL: "The WashU-HHMI Mouse EST project", XP002169411 *
DATABASE EMBL 19 April 1997 (1997-04-19), M.D. ADAMS ET AL: "EST186826 HCC cell line (metastasis to liver in mouse ) II Homo sapiens cDNA 5' end, mRNA sequence", XP002169413 *
DATABASE EMBL 30 August 2000 (2000-08-30), A. PIETAS ET AL: "Human cDNA of a new member of the S100 protein family which is down regulated in lung carcinoma cells", XP002169416 *
DATABASE EMBL 31 October 1997 (1997-10-31), M. MARRA ET AL: "The WashU-HHMI Mouse EST Project", XP002169412 *
DATABASE EMBL 8 January 1998 (1998-01-08), M. MARRA ET AL: "The WashU-HHMI Mouse EST project", XP002169414 *
DATABASE EMBL 8 May 1996 (1996-05-08), M. MARRA ET AL: "The WashU-HHMi Mouse EST Project", XP002169415 *
M.D. ADAMS ET AL: "Initial assessment of human gene diversity and expression patterns based upon 83 million nucleotides of cDNA", NATURE, vol. 377, no. 6547 suppl, 1995, pages 3 - 174 *
UNPUBLISHED *

Also Published As

Publication number Publication date
WO2001036644A2 (en) 2001-05-25
EP1230370A2 (en) 2002-08-14

Similar Documents

Publication Publication Date Title
WO2000058473A3 (en) Nucleic acids including open reading frames encoding polypeptides; 'orfx'
WO2001007595A3 (en) Novel fibroblast growth factor and nucleic acids encoding same
WO2001092523A3 (en) Human polynucleotides and polypeptides encoded thereby
WO2003000842A3 (en) Novel proteins and nucleic acids encoding same
WO2001036645A3 (en) Serine/threonine kinase and serine protease polypeptides and nucleic acids encoding same
WO2002081498A3 (en) Novel proteins and nucleic acids encoding same
WO2000053742A3 (en) Polynucleotides and proteins encoded thereby
WO2001049729A3 (en) Novex polypeptides, nucleic acids encoding same and their diagnostic and therapeutic use
WO2002066647A3 (en) Type 2 ctokine receptor and nucleic acids encoding same
WO2001074856A3 (en) Wnt-7b-like polypeptides and nucleic acids encoding same
WO2002002625A3 (en) Novel fibroblast growth factors and nucleic acids encoding same
WO2001070978A3 (en) Polypeptides and nucleic acids encoding same
WO2001062928A3 (en) Polypeptides and nucleic acids encoding same
WO2001061009A3 (en) Polypeptides and nucleic acids encoding same
WO2001044473A3 (en) Polypeptides and nucleic acids encoding same
WO2001036638A3 (en) Polypeptides and nucleic acids encoding same
WO2002072757A3 (en) Novel proteins and nucleic acids encoding same
WO2003025147A3 (en) Novel polynucleotides and proteins encoded thereby
WO2000070046A3 (en) Secreted polypeptides and corresponding polynucleotides
WO2000061754A3 (en) Human proteins and polynucleotides encoding them
WO2001036644A3 (en) Wnt-regulated cytokine-like polypeptide and nucleic acids encoding same
WO2001085767A3 (en) Human proteins polynucleotides encoding them and methods of using the same
WO2001068851A3 (en) Polypeptides and nucleic acids encoding same
WO2003040345A3 (en) Type 2 cytokine receptor and nucleic acids encoding same
WO2001023561A3 (en) Novel polynucleotides encoding proteins containing thrombospondin type 1 repeats

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CR CU CZ DE DK DM DZ EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG US US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
AK Designated states

Kind code of ref document: A3

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CR CU CZ DE DK DM DZ EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG US US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

WWE Wipo information: entry into national phase

Ref document number: 2391380

Country of ref document: CA

Ref document number: 16194/01

Country of ref document: AU

WWE Wipo information: entry into national phase

Ref document number: 2000978769

Country of ref document: EP

WWP Wipo information: published in national office

Ref document number: 2000978769

Country of ref document: EP

REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

NENP Non-entry into the national phase

Ref country code: JP

点击 这是indexloc提供的php浏览器服务，不要输入任何密码和下载